Tri Locum Partners LP Quant / Systematic

Location: New York, NY

CIK: 0001826434 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 18, 2026

Total Value: $713M (100.0% shares, 0.0% debt)

Holdings (17)

New Positions (6)

ISRG INTUITIVE SURGICAL INC 9.9%

Value $70.65M Shares 153,250 Est. Cost $520.97 Unrealized 0.0%

TMO THERMO FISHER SCIENTIFIC INC 9.1%

Value $65.08M Shares 132,413 Est. Cost $574.61 Unrealized 0.0%

VRTX VERTEX PHARMACEUTICALS INC 8.1%

Value $57.74M Shares 129,314 Est. Cost $467.55 Unrealized 0.0%

JAZZ JAZZ PHARMACEUTICALS PLC 4.2%

Value $30M Shares 158,663 Est. Cost $169.07 Unrealized 0.0%

TARS TARSUS PHARMACEUTICALS INC 2.5%

Value $17.72M Shares 252,588 Est. Cost $69.71 Unrealized 0.0%

DFTX DEFINIUM THERAPEUTICS INC 1.0%

Value $6.985M Shares 369,588 Est. Cost $16.29 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ISRG	INTUITIVE SURGICAL INC	153,250	$70.65M	9.9%	$520.97	0.0%	COM NEW	46120E602
TMO	THERMO FISHER SCIENTIFIC INC	132,413	$65.08M	9.1%	$574.61	0.0%	COM	883556102
VRTX	VERTEX PHARMACEUTICALS INC	129,314	$57.74M	8.1%	$467.55	0.0%	COM	92532F100
JAZZ	JAZZ PHARMACEUTICALS PLC	158,663	$30M	4.2%	$169.07	0.0%	SHS USD	G50871105
TARS	TARSUS PHARMACEUTICALS INC	252,588	$17.72M	2.5%	$69.71	0.0%	COM	87650L103
DFTX	DEFINIUM THERAPEUTICS INC	369,588	$6.985M	1.0%	$16.29	0.0%	COM SHS	24477V105

Increased Positions (2)

DXCM DEXCOM INC 6.2%

Value $43.84M (+56.7%) Shares 698,158 (+65.6%) Est. Cost $67.13 Unrealized +5.6%

MDGL MADRIGAL PHARMACEUTICALS INC 7.6%

Value $54.07M (+7.9%) Shares 103,288 (+20.1%) Est. Cost $348.56 Unrealized +41.3%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
DXCM	DEXCOM INC	698,158 (+65.6%)	$43.84M (+56.7%)	6.2%	$67.13	+5.6%	COM	252131107
MDGL	MADRIGAL PHARMACEUTICALS INC	103,288 (+20.1%)	$54.07M (+7.9%)	7.6%	$348.56	+41.3%	COM	558868105

Exited Positions (4)

DHR DANAHER CORPORATION 11.1%

Value $79.41M Shares 346,875 Est. Cost $219.54 Unrealized +2.3%

BSX BOSTON SCIENTIFIC CORP 7.0%

Value $49.63M Shares 520,508 Est. Cost $98.04 Unrealized -12.5%

IONS IONIS PHARMACEUTICALS INC 6.2%

Value $44.08M Shares 557,174 Est. Cost $75.30 Unrealized +8.6%

VERA VERA THERAPEUTICS INC 5.7%

Value $40.8M Shares 805,689 Est. Cost $24.12 Unrealized +86.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
DHR	DANAHER CORPORATION	346,875	$79.41M	11.1%	$219.54	+2.3%	—	235851102
BSX	BOSTON SCIENTIFIC CORP	520,508	$49.63M	7.0%	$98.04	-12.5%	—	101137107
IONS	IONIS PHARMACEUTICALS INC	557,174	$44.08M	6.2%	$75.30	+8.6%	—	462222100
VERA	VERA THERAPEUTICS INC	805,689	$40.8M	5.7%	$24.12	+86.4%	—	92337R101

Decreased Positions (8)

AXSM AXSOME THERAPEUTICS INC. 1.5%

Value $10.5M (-71.5%) Shares 62,116 (-69.2%) Est. Cost $101.43 Unrealized +77.7%

JNJ JOHNSON & JOHNSON 14.2%

Value $101M (-18.8%) Shares 414,503 (-31.3%) Est. Cost $183.20 Unrealized +24.4%

UTHR UNITED THERAPEUTICS CORP DEL 5.9%

Value $41.73M (-29.2%) Shares 70,370 (-41.8%) Est. Cost $336.31 Unrealized +42.9%

TEVA TEVA PHARMACEUTICAL INDS LTD 4.3%

Value $30.75M (-31.4%) Shares 1,021,008 (-28.9%) Est. Cost $31.21 Unrealized —

DNTH DIANTHUS THERAPEUTICS INC 1.7%

Value $12.21M (-52.4%) Shares 145,543 (-76.6%) Est. Cost $34.89 Unrealized +36.4%

LLY ELI LILLY & CO 8.0%

Value $56.84M (-16.4%) Shares 61,795 (-2.4%) Est. Cost $955.55 Unrealized +9.6%

ARGX ARGENX SE 3.2%

Value $23.1M (-27.0%) Shares 31,635 (-16.0%) Est. Cost $507.27 Unrealized —

ASND ASCENDIS PHARMA A/S 8.2%

Value $58.4M (+3.3%) Shares 255,332 (-3.7%) Est. Cost $187.08 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
AXSM	AXSOME THERAPEUTICS INC.	62,116 (-69.2%)	$10.5M (-71.5%)	1.5%	$101.43	+77.7%	COM	05464T104
JNJ	JOHNSON & JOHNSON	414,503 (-31.3%)	$101M (-18.8%)	14.2%	$183.20	+24.4%	COM	478160104
UTHR	UNITED THERAPEUTICS CORP DEL	70,370 (-41.8%)	$41.73M (-29.2%)	5.9%	$336.31	+42.9%	COM	91307C102
TEVA	TEVA PHARMACEUTICAL INDS LTD	1,021,008 (-28.9%)	$30.75M (-31.4%)	4.3%	$31.21	—	SPONSORED ADS	881624209
DNTH	DIANTHUS THERAPEUTICS INC	145,543 (-76.6%)	$12.21M (-52.4%)	1.7%	$34.89	+36.4%	COM	252828108
LLY	ELI LILLY & CO	61,795 (-2.4%)	$56.84M (-16.4%)	8.0%	$955.55	+9.6%	COM	532457108
ARGX	ARGENX SE	31,635 (-16.0%)	$23.1M (-27.0%)	3.2%	$507.27	—	SPONSORED ADR	04016X101
ASND	ASCENDIS PHARMA A/S	255,332 (-3.7%)	$58.4M (+3.3%)	8.2%	$187.08	—	SPONSORED ADR	04351P101

Unchanged Positions (1)

NUVL NUVALENT INC 4.4%

Value $31.61M Shares 308,506 Est. Cost $98.60 Unrealized +5.1%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
NUVL	NUVALENT INC	308,506	$31.61M	4.4%	$98.60	+5.1%	COM	670703107