Frazier Life Sciences Management, L.P. Diversified Active

Location: Palo Alto, CA

CIK: 0001892134 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 13, 2026

Total Value: $3.723B (100.0% shares, 0.0% debt)

Holdings (40)

NAMS NEWAMSTERDAM PHARMA COMPANY 16.0%
Value $594M Shares 16,943,774 Est. Cost $13.41 Unrealized +171.4%
MIRM MIRUM PHARMACEUTICALS INC 14.4%
Value $537M Shares 6,795,121 Est. Cost $24.28 Unrealized +195.7%
ARQT ARCUTIS BIOTHERAPEUTICS INC 7.7%
Value $287M Shares 9,874,511 Est. Cost $16.74 Unrealized +52.9%
BBIO BRIDGEBIO PHARMA INC 7.3%
Value $271M Shares 3,545,557 Est. Cost $21.54 Unrealized +204.7%
MBX MBX BIOSCIENCES INC 5.6%
Value $210M Shares 6,652,013 Est. Cost $21.92 Unrealized +10.7%
PHAT PHATHOM PHARMACEUTICALS INC 5.6%
Value $207M Shares 12,466,489 Est. Cost $12.14 Unrealized +17.6%
MAZE MAZE THERAPEUTICS INC 5.1%
Value $189M Shares 4,567,274 Est. Cost $11.88 Unrealized +189.3%
TRVI TREVI THERAPEUTICS INC 3.4%
Value $128M Shares 10,259,409 Est. Cost $2.91 Unrealized +296.9%
KRYS KRYSTAL BIOTECH INC 3.2%
Value $120M Shares 488,460 Est. Cost $64.17 Unrealized +228.0%
IRON DISC MEDICINE INC 2.7%
Value $100M Shares 1,260,000 Est. Cost $35.82 Unrealized +135.9%
ERAS ERASCA INC 2.3%
Value $84.55M Shares 22,729,436 Est. Cost $2.19 Unrealized +28.5%
KALV KALVISTA PHARMACEUTICALS INC 2.2%
Value $81.39M Shares 5,039,867 Est. Cost $10.00 Unrealized +32.4%
PVLA PALVELLA THERAPEUTICS INC NE 2.0%
Value $75.61M Shares 722,400 Est. Cost $16.23 Unrealized +425.5%
RNAM AVIDITY BIOSCIENCES INC 1.9%
Value $70.91M Shares 983,125 Est. Cost $43.19 Unrealized +49.5%
RVMD REVOLUTION MEDICINES INC 1.7%
Value $63.52M Shares 797,455 Est. Cost $25.35 Unrealized +158.7%
DYN DYNE THERAPEUTICS INC 1.7%
Value $61.67M Shares 3,153,082 Est. Cost $13.76 Unrealized +37.6%
TARS TARSUS PHARMACEUTICALS INC 1.6%
Value $59.66M Shares 728,644 Est. Cost $17.82 Unrealized +318.9%
SVRA SAVARA INC 1.6%
Value $59.47M Shares 9,862,301 Est. Cost $3.69 Unrealized +32.9%
CYTK CYTOKINETICS INC 1.6%
Value $59.39M Shares 934,642 Est. Cost $38.38 Unrealized +62.1%
ABVX ABIVAX SA 1.4%
Value $51.02M Shares 378,300 Est. Cost $84.90 Unrealized —
LXEO LEXEO THERAPEUTICS INC 1.2%
Value $43.94M Shares 4,424,725 Est. Cost $5.15 Unrealized +77.1%
AGIO AGIOS PHARMACEUTICALS INC 0.9%
Value $34.83M Shares 1,279,754 Est. Cost $31.94 Unrealized +9.8%
ACAD ACADIA PHARMACEUTICALS INC 0.9%
Value $34.65M Shares 1,297,198 Est. Cost $23.78 Unrealized +0.5%
ZLAB ZAI LAB LTD 0.9%
Value $33.56M Shares 1,902,320 Est. Cost $32.50 Unrealized —
RAPT RAPT THERAPEUTICS INC 0.9%
Value $33.31M Shares 983,333 Est. Cost $31.06 Unrealized 0.0%
VOR VOR BIOPHARMA INC 0.9%
Value $33.27M Shares 2,543,939 Est. Cost $18.62 Unrealized 0.0%
ASND ASCENDIS PHARMA A/S 0.8%
Value $28.43M Shares 133,333 Est. Cost $149.31 Unrealized —
AURA AURA BIOSCIENCES INC 0.7%
Value $27.8M Shares 5,100,000 Est. Cost $5.85 Unrealized +1.5%
MNKD MANNKIND CORP 0.6%
Value $23.96M Shares 4,225,000 Est. Cost $5.51 Unrealized 0.0%
VALN VALNEVA SE 0.5%
Value $20.21M Shares 2,291,666 Est. Cost $8.03 Unrealized —
ALKS ALKERMES PLC 0.5%
Value $19.6M Shares 700,647 Est. Cost $27.95 Unrealized +7.2%
EOLS EVOLUS INC 0.5%
Value $17.49M Shares 2,630,665 Est. Cost $10.05 Unrealized -32.6%
IMCR IMMUNOCORE HLDGS PLC 0.4%
Value $13.36M Shares 384,782 Est. Cost $31.23 Unrealized —
NAMSW NEWAMSTERDAM PHARMA COMPANY 0.3%
Value $11.51M Shares 500,333 Est. Cost $0.87 Unrealized —
TVTX TRAVERE THERAPEUTICS INC 0.2%
Value $9.231M Shares 241,592 Est. Cost $16.57 Unrealized +96.2%
AUTL AUTOLUS THERAPEUTICS PLC 0.2%
Value $9.2M Shares 4,623,324 Est. Cost $4.59 Unrealized —
ALLO ALLOGENE THERAPEUTICS INC 0.1%
Value $5.3M Shares 3,868,750 Est. Cost $3.58 Unrealized -63.2%
DSGN DESIGN THERAPEUTICS INC 0.1%
Value $4.887M Shares 521,000 Est. Cost $4.24 Unrealized +84.5%
XLO XILIO THERAPEUTICS INC 0.1%
Value $3.787M Shares 5,915,091 Est. Cost $0.75 Unrealized 0.0%
IBIO IBIO INC 0.1%
Value $3.77M Shares 1,953,467 Est. Cost $1.36 Unrealized 0.0%