SIONNA THERAPEUTICS INC

Ticker: SION CUSIP: 829401108 Class: Common Stock

Note: Option positions (PUT/CALL) are excluded.

New Positions (29)

Increased Positions (38)

Longaeva Partners L.P.
Value ($000) $3,280 (+81.5%) Shares 79,729 (+29.7%)
CITADEL ADVISORS LLC
Value ($000) $44,733 (+4134.1%) Shares 1,087,325 (+2926.8%)
China Universal Asset Management Co., Ltd.
Value ($000) $423 (+187.4%) Shares 10,272 (+105.4%)
JENNISON ASSOCIATES LLC
Value ($000) $45,883 (+56.4%) Shares 1,115,278 (+11.8%)
STATE STREET CORP
Value ($000) $28,526 (+303.8%) Shares 693,395 (+188.7%)
BlackRock, Inc.
Value ($000) $53,136 (+113.9%) Shares 1,291,599 (+52.9%)
MANUFACTURERS LIFE INSURANCE COMPANY, THE
Value ($000) $2,872 (+204.4%) Shares 69,424 (+116.4%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $15,638 (+67.9%) Shares 380,042 (+20.1%)
UBS Group AG
Value ($000) $3,669 (+167.3%) Shares 89,177 (+91.1%)
TD Asset Management Inc
Value ($000) $4,663 (+82.1%) Shares 113,352 (+30.2%)
VANGUARD GROUP INC
Value ($000) $48,749 (+45.0%) Shares 1,184,951 (+3.7%)
BANK OF AMERICA CORP /DE/
Value ($000) $1,792 (+831.7%) Shares 43,567 (+566.1%)
Russell Investments Group, Ltd.
Value ($000) $903 (+2903.3%) Shares 21,941 (+2046.9%)
MORGAN STANLEY
Value ($000) $2,052 (+205.5%) Shares 49,876 (+118.4%)
GOLDMAN SACHS GROUP INC
Value ($000) $1,492 (+316.6%) Shares 36,269 (+197.8%)
NORTHERN TRUST CORP
Value ($000) $4,612 (+60.5%) Shares 112,116 (+14.7%)
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
Value ($000) $5,088 (+55.2%) Shares 123,686 (+10.9%)
WELLS FARGO & COMPANY/MN
Value ($000) $722 (+224.1%) Shares 17,551 (+131.7%)
Nuveen, LLC
Value ($000) $976 (+107.0%) Shares 23,734 (+48.0%)
Bank of New York Mellon Corp
Value ($000) $1,445 (+79.0%) Shares 35,134 (+27.9%)

Decreased Positions (20)

Atlas Venture Life Science Advisors, LLC
Value ($000) $123,239 (+15.9%) Shares 2,995,602 (-17.1%)
RA CAPITAL MANAGEMENT, L.P.
Value ($000) $407,494 (+32.6%) Shares 9,905,045 (-5.2%)
ORBIMED ADVISORS LLC
Value ($000) $146,526 (+34.5%) Shares 3,561,655 (-3.9%)
SILVERARC CAPITAL MANAGEMENT, LLC
Value ($000) $1,706 (-46.7%) Shares 41,460 (-61.9%)
Soleus Capital Management, L.P.
Value ($000) $11,046 (-9.2%) Shares 268,500 (-35.1%)
Siren, L.L.C.
Value ($000) $12,342 (+29.1%) Shares 300,000 (-7.7%)
abrdn plc
Value ($000) $34,556 (+23.6%) Shares 839,960 (-11.6%)
JPMORGAN CHASE & CO
Value ($000) $50,677 (-12.9%) Shares 1,231,819 (-37.7%)
Alyeska Investment Group, L.P.
Value ($000) $5,604 (+2.3%) Shares 136,222 (-26.8%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $3,314 (-47.4%) Shares 80,546 (-62.4%)
FRANKLIN RESOURCES INC
Value ($000) $7,219 (+1.4%) Shares 175,483 (-27.5%)
AMERIPRISE FINANCIAL INC
Value ($000) $4,182 (-7.2%) Shares 101,643 (-33.6%)
Tower Research Capital LLC (TRC)
Value ($000) $46 (-64.8%) Shares 1,129 (-74.9%)
Virtus Investment Advisers, LLC
Value ($000) $256 (+29.9%) Shares 6,220 (-7.1%)
Aster Capital Management (DIFC) Ltd
Value ($000) $2 (-87.3%) Shares 37 (-91.0%)
Legal & General Group Plc
Value ($000) $69 (-68.1%) Shares 1,682 (-77.2%)
WELLINGTON MANAGEMENT GROUP LLP
Value ($000) $1,578 (+27.0%) Shares 38,347 (-9.2%)
BNP PARIBAS ARBITRAGE, SA
Value ($000) $93 (+33.1%) Shares 2,264 (-4.9%)
US BANCORP \DE\
Value ($000) $3 (-18.1%) Shares 65 (-41.4%)
Hughes Financial Services, LLC
Value ($000) $1 (-34.6%) Shares 25 (-43.2%)