Location: San Francisco, CA
CIK: 0001587114 · Show all filings
Period: Q3 2022 (← Previous) (Next →)
Filing Date: Nov 14, 2022
Total Value: $3.388B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | 11,584,280 | $702M | 20.7% | $11.63 | +171.7% | SHS | G72800108 |
| APLS | APELLIS PHARMACEUTICALS INC | 5,183,431 | $354M | 10.4% | $40.43 | +46.4% | COM | 03753U106 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,999,453 | $332M | 9.8% | $76.84 | +31.2% | COM | 803607100 |
| ANAB | ANAPTYSBIO INC | 7,521,024 | $192M | 5.7% | $23.15 | +1.3% | COM | 032724106 |
| ARVN | ARVINAS INC | 3,123,300 | $139M | 4.1% | $59.39 | -18.2% | COM | 04335A105 |
| XNCR | XENCOR INC | 5,282,516 | $137M | 4.1% | $33.50 | -14.5% | COM | 98401F105 |
| GLPG | GALAPAGOS NV | 3,197,500 | $136M | 4.0% | $55.99 | — | SPON ADR | 36315X101 |
| — | MORPHIC HLDG INC | 3,951,566 | $112M | 3.3% | $29.75 | — | COM | 61775R105 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,460,208 | $98.72M | 2.9% | $28.53 | — | COM | 85205L107 |
| ACAD | ACADIA PHARMACEUTICALS INC | 5,991,479 | $98.02M | 2.9% | $22.11 | -26.8% | COM | 004225108 |
| RLAY | RELAY THERAPEUTICS INC | 4,163,824 | $93.14M | 2.7% | $28.03 | -21.7% | COM | 75943R102 |
| KURA | KURA ONCOLOGY INC | 6,638,371 | $90.68M | 2.7% | $18.76 | -17.8% | COM | 50127T109 |
| — | MIRATI THERAPEUTICS INC | 1,015,572 | $70.93M | 2.1% | $69.84 | — | COM | 60468T105 |
| ZLAB | ZAI LAB LTD | 2,030,252 | $69.44M | 2.0% | $43.18 | — | ADR | 98887Q104 |
| GOSS | GOSSAMER BIO INC | 4,160,887 | $49.85M | 1.5% | $12.41 | 0.0% | COM | 38341P102 |
| ALLO | ALLOGENE THERAPEUTICS INC | 4,488,200 | $48.47M | 1.4% | $8.88 | +53.1% | COM | 019770106 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,899,285 | $47.34M | 1.4% | $26.76 | -28.5% | COM | 05370A108 |
| DSGN | DESIGN THERAPEUTICS INC | 2,519,268 | $42.12M | 1.2% | $22.94 | -13.2% | COM | 25056L103 |
| — | SEAGEN INC | 285,793 | $39.1M | 1.2% | $176.94 | — | COM | 81181C104 |
| ALEC | ALECTOR INC | 4,056,548 | $38.38M | 1.1% | $19.56 | -44.7% | COM | 014442107 |
| RVMD | REVOLUTION MEDICINES INC | 1,801,847 | $35.53M | 1.0% | $20.15 | +9.1% | COM | 76155X100 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,184,861 | $35.19M | 1.0% | $14.25 | -46.3% | COM | 04683R106 |
| EWTX | EDGEWISE THERAPEUTICS INC | 3,493,194 | $34.37M | 1.0% | $18.91 | -46.6% | COM | 28036F105 |
| — | 2SEVENTY BIO INC | 2,341,313 | $34.07M | 1.0% | $21.76 | — | COMMON STOCK | 901384107 |
| NUVB | NUVATION BIO INC | 13,896,543 | $31.13M | 0.9% | $11.16 | -74.4% | COM CL A | 67080N101 |
| VYGR | VOYAGER THERAPEUTICS INC | 4,753,907 | $28.14M | 0.8% | $3.51 | — | COM | 92915B106 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1,330,263 | $26.13M | 0.8% | $22.08 | -7.7% | COM | 22663K107 |
| JANX | JANUX THERAPEUTICS INC | 1,421,319 | $19.25M | 0.6% | $22.27 | -40.0% | COM | 47103J105 |
| KYMR | KYMERA THERAPEUTICS INC | 796,093 | $17.33M | 0.5% | $26.36 | 0.0% | COM | 501575104 |
| TNGX | TANGO THERAPEUTICS INC | 4,201,414 | $15.21M | 0.4% | $6.32 | -32.5% | COM | 87583X109 |
| CGEM | CULLINAN ONCOLOGY INC | 1,143,218 | $14.66M | 0.4% | $11.34 | +18.8% | COM | 230031106 |
| VTYX | VENTYX BIOSCIENCES INC | 400,000 | $13.96M | 0.4% | $18.95 | +16.8% | COM | 92332V107 |
| — | CHINOOK THERAPEUTICS INC | 690,000 | $13.56M | 0.4% | $16.36 | — | COM | 16961L106 |
| — | AKOUOS INC | 1,975,984 | $13.36M | 0.4% | $22.50 | — | COM | 00973J101 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 3,236,352 | $13.01M | 0.4% | $5.52 | — | SPONSORED ADS | 152309100 |
| OVID | OVID THERAPEUTICS INC | 6,117,400 | $11.26M | 0.3% | $3.32 | -37.0% | COM | 690469101 |
| ORIC | ORIC PHARMACEUTICALS INC | 3,418,068 | $10.94M | 0.3% | $30.24 | -86.8% | COM | 68622P109 |
| — | POSEIDA THERAPEUTICS INC | 2,650,000 | $9.355M | 0.3% | $3.53 | — | COM | 73730P108 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 415,322 | $7.937M | 0.2% | $16.92 | +33.9% | COM | 03969K108 |
| — | NGM BIOPHARMACEUTICALS INC | 541,108 | $7.078M | 0.2% | $15.25 | — | COM | 62921N105 |
| — | HOOKIPA PHARMA INC | 5,000,000 | $6.7M | 0.2% | $2.28 | — | COM | 43906K100 |
| — | PRECISION BIOSCIENCES INC | 5,035,971 | $6.547M | 0.2% | $1.60 | — | COM | 74019P108 |
| ARGX | ARGENX SE | 17,527 | $6.188M | 0.2% | $315.31 | — | SPONSORED ADR | 04016X101 |
| — | GRACELL BIOTECHNOLOGIES INC | 1,921,310 | $6.187M | 0.2% | $2.93 | — | SPONSORED ADS | 38406L103 |
| — | SELECTA BIOSCIENCES INC | 3,500,000 | $5.74M | 0.2% | $1.31 | — | COM | 816212104 |
| GERN | GERON CORP | 2,301,980 | $5.387M | 0.2% | $1.11 | +100.8% | COM | 374163103 |
| — | AVEO PHARMACEUTICALS INC | 650,489 | $5.354M | 0.2% | $6.56 | — | COM NEW | 053588307 |
| ERAS | ERASCA INC | 678,441 | $5.292M | 0.2% | $20.63 | -61.0% | COM | 29479A108 |
| — | GRAPHITE BIO INC | 1,582,135 | $5.015M | 0.1% | $7.57 | — | COM | 38870X104 |
| — | JIYA ACQUISITION CORP | 500,000 | $4.985M | 0.1% | $10.30 | — | COM CL A | 47760M102 |
| — | FRAZIER LIFESCIENCES ACQU CO | 487,615 | $4.862M | 0.1% | $9.80 | — | CL A SHS | G3710A105 |
| — | ALIGOS THERAPEUTICS INC | 3,948,360 | $4.343M | 0.1% | $2.37 | — | COM | 01626L105 |
| — | SURFACE ONCOLOGY INC | 3,924,713 | $4.082M | 0.1% | $2.94 | — | COM | 86877M209 |
| — | HEALTH SCIENCES ACQ CORP 2 | 400,000 | $3.96M | 0.1% | $11.00 | — | ORD SHS | G4411D109 |
| — | PRAXIS PRECISION MEDICINES I | 1,496,324 | $3.397M | 0.1% | $2.30 | — | COM | 74006W108 |
| MGNX | MACROGENICS INC | 930,955 | $3.221M | 0.1% | $3.83 | 0.0% | COM | 556099109 |
| ASND | ASCENDIS PHARMA A/S | 27,208 | $2.809M | 0.1% | $103.24 | — | SPONSORED ADR | 04351P101 |
| — | NUVATION BIO INC | 963,333 | $2.158M | 0.1% | $10.45 | — | *W EXP 07/07/202 | 67080N119 |
| — | KINNATE BIOPHARMA INC | 175,000 | $2.091M | 0.1% | $25.42 | — | COM | 49705R105 |
| — | EUCRATES BIOMEDICAL ACQU COR | 200,000 | $2.004M | 0.1% | $9.98 | — | SHS | G3141W106 |
| — | BCLS ACQUISITION CORP | 200,000 | $2.004M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | 5 01 ACQUISITION CORP | 200,000 | $2M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | TEMPEST THERAPEUTICS INC | 1,031,268 | $1.794M | 0.1% | $2.15 | — | COM | 87978U108 |
| — | ARYA SCIENCES ACQU CORP IV | 150,000 | $1.487M | 0.0% | $10.47 | — | CL A | G31659108 |
| — | KRONOS BIO INC | 326,780 | $1.095M | 0.0% | $29.87 | — | COM | 50107A104 |
| DSGN | DESIGN THERAPEUTICS INC | 63,400 | $1.06M | 0.0% | $22.94 | -13.2% | Call | 25056L103 |
| — | TURMERIC ACQUISITION CORP | 100,000 | $1M | 0.0% | $9.77 | — | CL A | G9127T108 |
| — | REATA PHARMACEUTICALS INC | 38,467 | $967K | 0.0% | $32.76 | — | CL A | 75615P103 |
| NUVL | NUVALENT INC | 40,970 | $796K | 0.0% | $16.74 | 0.0% | COM | 670703107 |
| — | ITEOS THERAPEUTICS INC | 40,480 | $771K | 0.0% | $21.93 | — | COM | 46565G104 |
| — | CAREMAX INC | 100,000 | $709K | 0.0% | $12.90 | — | *W EXP 06/08/202 | 14171W111 |
| — | EUCRATES BIOMEDICAL ACQU COR | 66,666 | $668K | 0.0% | $9.90 | — | *W EXP 10/23/202 | G3141W122 |
| — | FRAZIER LIFESCIENCES ACQU CO | 66,665 | $665K | 0.0% | $9.77 | — | *W EXP 11/30/202 | G3710A113 |
| — | OMEGA ALPHA SPAC | 50,000 | $497K | 0.0% | $9.90 | — | CL A | G6749V107 |
| — | TURMERIC ACQUISITION CORP | 33,333 | $333K | 0.0% | $9.78 | — | *W EXP 10/08/202 | G9127T124 |
| SRZNW | SURROZEN INC | 66,665 | $135K | 0.0% | $7.07 | — | *W EXP 08/01/203 | 86889P117 |