Location: Larkspur, CA
CIK: 0001425738 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $4.399B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FATE | FATE THERAPEUTICS INC | 12,957,222 | $758M | 17.2% | $58.51 * | $13.22 | +328.7% | COM | 31189P102 |
| FOLD | AMICUS THERAPEUTICS INC | 22,716,086 | $262M | 6.0% | $11.55 * | $10.66 | +4.6% | COM | 03152W109 |
| — | SCIENCE 37 HOLDINGS INC | 19,808,234 | $247M | 5.6% | $12.47 | $12.47 | — | COM | 808644108 |
| ARGX | ARGENX SE | 521,643 | $183M | 4.2% | $350.19 | $87.46 | — | SPONSORED ADR | 04016X101 |
| LIVN | LIVANOVA PLC | 2,057,178 | $180M | 4.1% | $87.43 * | $76.69 | +8.7% | SHS | G5509L101 |
| KYMR | KYMERA THERAPEUTICS INC | 2,587,730 | $164M | 3.7% | $63.49 * | $33.10 | +76.0% | COM | 501575104 |
| ADCT | ADC THERAPEUTICS SA | 7,451,029 | $151M | 3.4% | $20.20 * | $37.38 | -35.5% | SHS | H0036K147 |
| BEAM | BEAM THERAPEUTICS INC | 1,885,850 | $150M | 3.4% | $79.69 * | $25.01 | +242.4% | COM | 07373V105 |
| KRYS | KRYSTAL BIOTECH INC | 1,820,898 | $127M | 2.9% | $69.95 * | $43.09 | +35.1% | COM | 501147102 |
| SKIN | THE BEAUTY HEALTH COMPANY | 5,082,805 | $123M | 2.8% | $24.16 * | $14.93 | +72.6% | COM CL A | 88331L108 |
| REPL | REPLIMUNE GROUP INC | 3,866,512 | $105M | 2.4% | $27.10 * | $21.94 | +36.3% | COM | 76029N106 |
| — | ATARA BIOTHERAPEUTICS INC | 6,437,777 | $101M | 2.3% | $15.76 | $23.37 | — | COM | 046513107 |
| — | IGM BIOSCIENCES INC | 3,334,355 | $97.8M | 2.2% | $29.33 | $22.36 | — | COM | 449585108 |
| NRIX | NURIX THERAPEUTICS INC | 2,958,284 | $85.64M | 1.9% | $28.95 * | $27.59 | +9.9% | COM | 67080M103 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 2,165,586 | $83.68M | 1.9% | $38.64 * | $11.39 | +282.6% | COM NEW | 15117B202 |
| ABSI | ABSCI CORPORATION | 8,031,094 | $65.86M | 1.5% | $8.20 * | $19.41 | -41.3% | COM | 00091E109 |
| — | VERVE THERAPEUTICS INC | 1,708,536 | $62.99M | 1.4% | $36.87 | $60.25 | — | COM | 92539P101 |
| RGNX | REGENXBIO INC | 1,897,223 | $62.04M | 1.4% | $32.70 * | $33.61 | +1.3% | COM | 75901B107 |
| — | IMMUNOGEN INC | 8,258,345 | $61.28M | 1.4% | $7.42 | $5.36 | — | COM | 45253H101 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,447,926 | $60.81M | 1.4% | $24.84 * | $20.60 | +34.0% | COM | 80706P103 |
| — | REPARE THERAPEUTICS INC | 2,789,496 | $58.83M | 1.3% | $21.09 | $30.51 | — | COM | 760273102 |
| — | INVITAE CORP | 3,805,403 | $58.11M | 1.3% | $15.27 | $39.75 | — | COM | 46185L103 |
| — | SEAGEN INC | 371,839 | $57.49M | 1.3% | $154.60 | $138.86 | — | COM | 81181C104 |
| STOK | STOKE THERAPEUTICS INC | 2,246,668 | $53.9M | 1.2% | $23.99 | $26.54 | -10.1% | COM | 86150R107 |
| UNH | UNITEDHEALTH GROUP INC | 104,488 | $52.47M | 1.2% | $502.14 * | $324.86 | +30.0% | COM | 91324P102 |
| ICUI | ICU MED INC | 219,926 | $52.2M | 1.2% | $237.34 | $197.02 | +18.6% | COM | 44930G107 |
| ELV | ANTHEM INC | 110,289 | $51.12M | 1.2% | $463.54 * | $296.65 | +33.9% | COM | 036752103 |
| — | SOMALOGIC INC | 4,142,770 | $48.22M | 1.1% | $11.64 | $12.36 | — | CLASS A COM | 83444K105 |
| STTK | SHATTUCK LABS INC | 5,619,914 | $47.83M | 1.1% | $8.51 * | $32.14 | -57.1% | COM | 82024L103 |
| — | AUGMEDIX INC | 14,380,327 | $45.3M | 1.0% | $3.15 | $3.15 | — | COM | 05105P107 |
| — | GRITSTONE BIO INC | 3,429,171 | $44.1M | 1.0% | $12.86 | $12.85 | — | COM | 39868T105 |
| PLRX | PLIANT THERAPEUTICS INC | 3,083,501 | $41.63M | 0.9% | $13.50 * | $26.54 | -40.1% | COM | 729139105 |
| — | OAK STR HEALTH INC | 1,203,619 | $39.89M | 0.9% | $33.14 | $54.16 | — | COM | 67181A107 |
| PRTA | PROTHENA CORP PLC | 765,675 | $37.82M | 0.9% | $49.40 * | $18.81 | +194.7% | SHS | G72800108 |
| ANNX | ANNEXON INC | 3,228,917 | $37.1M | 0.8% | $11.49 * | $23.46 | -31.1% | COM | 03589W102 |
| — | AKERO THERAPEUTICS INC | 1,602,285 | $33.89M | 0.8% | $21.15 | $28.43 | — | COM | 00973Y108 |
| TRDA | ENTRADA THERAPEUTICS INC | 1,954,420 | $33.46M | 0.8% | $17.12 | $17.12 | — | COM | 29384C108 |
| NUVB | NUVATION BIO INC | 3,671,009 | $31.2M | 0.7% | $8.50 * | $11.18 | -17.8% | COM CL A | 67080N101 |
| CNC | CENTENE CORP DEL | 361,139 | $29.76M | 0.7% | $82.40 * | $73.27 | 0.0% | COM | 15135B101 |
| STVN | STEVANATO GROUP S P A | 1,170,225 | $26.27M | 0.6% | $22.45 * | $23.29 | +0.7% | ORD SHS | T9224W109 |
| GMAB | GENMAB A/S | 661,621 | $26.17M | 0.6% | $39.56 | $32.83 | — | SPONSORED ADS | 372303206 |
| — | IVERIC BIO INC | 1,500,000 | $25.08M | 0.6% | $16.72 | $16.72 | — | COM | 46583P102 |
| TOI | THE ONCOLOGY INSTITUTE INC | 2,500,000 | $24.38M | 0.6% | $9.75 * | $8.92 | 0.0% | COM | 68236X100 |
| IMTX | IMMATICS N.V | 1,765,692 | $23.73M | 0.5% | $13.44 * | $10.53 | +18.7% | SHS | N44445109 |
| — | NEVRO CORP | 270,116 | $21.9M | 0.5% | $81.07 | $110.34 | — | COM | 64157F103 |
| — | ALLAKOS INC | 2,077,875 | $20.34M | 0.5% | $9.79 | $61.43 | — | COM | 01671P100 |
| BVS | BIOVENTUS INC | 1,325,139 | $19.2M | 0.4% | $14.49 | $14.24 | -0.2% | COM CL A | 09075A108 |
| — | NEOLEUKIN THERAPEUTICS INC | 3,490,835 | $16.83M | 0.4% | $4.82 | $11.83 | — | COM | 64049K104 |
| ALXO | ALX ONCOLOGY HLDGS INC | 782,097 | $16.81M | 0.4% | $21.49 * | $51.82 | -16.8% | COM | 00166B105 |
| — | ZOGENIX INC | 998,114 | $16.22M | 0.4% | $16.25 | $15.19 | — | COM NEW | 98978L204 |
| — | MEDAVAIL HOLDINGS INC | 11,075,105 | $15.51M | 0.4% | $1.40 | $15.05 | — | COM | 58406B103 |
| — | LAVA THERAPEUTICS NV | 2,816,196 | $15.49M | 0.4% | $5.50 | $15.19 | — | SHS | N51517105 |
| TKNO | ALPHA TEKNOVA INC | 725,000 | $14.85M | 0.3% | $20.48 * | $25.30 | -12.4% | COM | 02080L102 |
| — | ZYMEWORKS INC | 874,397 | $14.33M | 0.3% | $16.39 | $38.68 | — | COM | 98985W102 |
| IVVD | ADAGIO THERAPEUTICS INC | 1,920,960 | $13.95M | 0.3% | $7.26 * | $37.11 | -29.9% | COM | 00534A102 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 98,064 | $12.49M | 0.3% | $127.40 * | $164.87 | -20.3% | SHS USD | G50871105 |
| — | ALLOVIR INC | 823,371 | $10.65M | 0.2% | $12.94 | $27.50 | — | COM | 019818103 |
| STXS | STEREOTAXIS INC | 1,698,204 | $10.53M | 0.2% | $6.20 * | $3.05 | +95.8% | COM NEW | 85916J409 |
| — | ACHILLES THERAPEUTICS PLC | 2,088,089 | $10.46M | 0.2% | $5.01 | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | NGM BIOPHARMACEUTICALS INC | 582,805 | $10.32M | 0.2% | $17.71 | $28.93 | — | COM | 62921N105 |
| RCEL | AVITA MEDICAL INC | 672,411 | $8.055M | 0.2% | $11.98 * | $24.93 | -38.8% | COM | 05380C102 |
| — | DECIPHERA PHARMACEUTICALS IN | 664,817 | $6.495M | 0.1% | $9.77 | $30.83 | — | COM | 24344T101 |
| — | TCR2 THERAPEUTICS INC | 1,346,058 | $6.273M | 0.1% | $4.66 | $17.10 | — | COM | 87808K106 |
| — | AYALA PHARMACEUTICALS INC | 667,816 | $5.683M | 0.1% | $8.51 | $10.03 | — | COM | 05465V108 |
| — | HOOKIPA PHARMA INC | 2,385,136 | $5.557M | 0.1% | $2.33 | $5.73 | — | COM | 43906K100 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 1,046,587 | $3.066M | 0.1% | $2.93 * | $2.16 | 0.0% | COM | 98422E103 |
| CTSO | CYTOSORBENTS CORP | 717,244 | $3.005M | 0.1% | $4.19 * | $9.04 | -37.9% | COM NEW | 23283X206 |
| — | SONENDO INC | 498,131 | $2.869M | 0.1% | $5.76 | $5.76 | — | COM | 835431107 |
| CABA | CABALETTA BIO INC | 696,377 | $2.639M | 0.1% | $3.79 * | $11.85 | -10.0% | COM | 12674W109 |
| — | ATRECA INC | 800,306 | $2.425M | 0.1% | $3.03 | $15.87 | — | CL A COM | 04965G109 |
| — | EPIZYME INC | 454,475 | $1.136M | 0.0% | $2.50 | $10.46 | — | COM | 29428V104 |