5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q2 2024 (← Previous) (Next →)

Filing Date: Aug 14, 2024

Total Value: $447M (100.0% shares, 0.0% debt)

Holdings (28)

SKYE SKYE BIOSCIENCE INC 18.2%

Value $81.54M Shares 10,179,505 Est. Cost $11.84 Unrealized 0.0%

TRDA ENTRADA THERAPEUTICS INC 14.1%

Value $62.82M Shares 4,408,379 Est. Cost $17.12 Unrealized —

ELVN ENLIVEN THERAPEUTICS INC 13.6%

Value $61.02M Shares 2,610,875 Est. Cost $20.34 Unrealized +3.5%

DNTH DIANTHUS THERAPEUTICS INC 7.1%

Value $31.91M Shares 1,232,965 Est. Cost $12.62 Unrealized +90.5%

CLDX CELLDEX THERAPEUTICS INC NEW 4.1%

Value $18.4M Shares 497,270 Est. Cost $32.09 Unrealized +17.6%

BHVN BIOHAVEN LTD 3.6%

Value $16.31M Shares 469,972 Est. Cost $33.79 Unrealized +17.0%

TYRA TYRA BIOSCIENCES INC 3.4%

Value $15.02M Shares 939,298 Est. Cost $15.18 Unrealized +13.4%

PHVS PHARVARIS N V 3.4%

Value $14.99M Shares 797,600 Est. Cost $19.05 Unrealized +6.8%

PRAX PRAXIS PRECISION MEDICINES I 3.1%

Value $14.06M Shares 340,000 Est. Cost $44.86 Unrealized +5.3%

ERAS ERASCA INC 2.9%

Value $12.76M Shares 5,405,404 Est. Cost $2.16 Unrealized 0.0%

VKTX VIKING THERAPEUTICS INC 2.8%

Value $12.59M Shares 237,560 Est. Cost $14.60 Unrealized +349.1%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 2.8%

Value $12.41M Shares 282,313 Est. Cost $25.81 Unrealized +64.1%

CNTA CENTESSA PHARMACEUTICALS PLC 2.5%

Value $11.24M Shares 1,245,000 Est. Cost $11.30 Unrealized —

TECX TECTONIC THERAPEUTIC INC 2.4%

Value $10.65M Shares 646,524 Est. Cost $15.77 Unrealized 0.0%

VRDN VIRIDIAN THERAPEUTICS INC 2.1%

Value $9.583M Shares 736,595 Est. Cost $17.93 Unrealized -22.8%

SLN SILENCE THERAPEUTICS PLC 2.0%

Value $9.048M Shares 476,200 Est. Cost $21.60 Unrealized —

ANAB ANAPTYSBIO INC 2.0%

Value $8.965M Shares 357,733 Est. Cost $28.24 Unrealized -17.6%

GHRS GH RESEARCH PLC 1.5%

Value $6.677M Shares 572,665 Est. Cost $10.15 Unrealized +18.3%

COGT COGENT BIOSCIENCES INC 1.5%

Value $6.663M Shares 790,440 Est. Cost $6.91 Unrealized +9.7%

— VOR BIOPHARMA INC 1.4%

Value $6.362M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— SCPHARMACEUTICALS INC 1.2%

Value $5.223M Shares 1,200,647 Est. Cost $5.92 Unrealized —

— RALLYBIO CORP 1.1%

Value $4.865M Shares 3,630,724 Est. Cost $17.58 Unrealized —

QTTB Q32 BIO INC 1.0%

Value $4.523M Shares 251,994 Est. Cost $13.78 Unrealized +73.6%

— ADVERUM BIOTECHNOLOGIES INC 0.8%

Value $3.716M Shares 541,666 Est. Cost $14.14 Unrealized —

— MERSANA THERAPEUTICS INC 0.6%

Value $2.623M Shares 1,305,000 Est. Cost $4.03 Unrealized —

ZNTL ZENTALIS PHARMACEUTICALS INC 0.4%

Value $2.004M Shares 490,000 Est. Cost $23.99 Unrealized -53.5%

— CIDARA THERAPEUTICS INC 0.2%

Value $677K Shares 56,725 Est. Cost $11.94 Unrealized —

EYPT EYEPOINT PHARMACEUTICALS INC 0.1%

Value $435K Shares 50,000 Est. Cost $13.97 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SKYE	SKYE BIOSCIENCE INC	10,179,505	$81.54M	18.2%	$11.84	0.0%	COM NEW	83086J200
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$62.82M	14.1%	$17.12	—	COM	29384C108
ELVN	ENLIVEN THERAPEUTICS INC	2,610,875	$61.02M	13.6%	$20.34	+3.5%	COM	29337E102
DNTH	DIANTHUS THERAPEUTICS INC	1,232,965	$31.91M	7.1%	$12.62	+90.5%	COM	252828108
CLDX	CELLDEX THERAPEUTICS INC NEW	497,270	$18.4M	4.1%	$32.09	+17.6%	COM NEW	15117B202
BHVN	BIOHAVEN LTD	469,972	$16.31M	3.6%	$33.79	+17.0%	COM	G1110E107
TYRA	TYRA BIOSCIENCES INC	939,298	$15.02M	3.4%	$15.18	+13.4%	COM	90240B106
PHVS	PHARVARIS N V	797,600	$14.99M	3.4%	$19.05	+6.8%	COM	N69605108
PRAX	PRAXIS PRECISION MEDICINES I	340,000	$14.06M	3.1%	$44.86	+5.3%	COM NEW	74006W207
ERAS	ERASCA INC	5,405,404	$12.76M	2.9%	$2.16	0.0%	COM	29479A108
VKTX	VIKING THERAPEUTICS INC	237,560	$12.59M	2.8%	$14.60	+349.1%	COM	92686J106
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	282,313	$12.41M	2.8%	$25.81	+64.1%	CLASS A ORD	61559X104
CNTA	CENTESSA PHARMACEUTICALS PLC	1,245,000	$11.24M	2.5%	$11.30	—	SPONSORED ADS	152309100
TECX	TECTONIC THERAPEUTIC INC	646,524	$10.65M	2.4%	$15.77	0.0%	COM	878972108
VRDN	VIRIDIAN THERAPEUTICS INC	736,595	$9.583M	2.1%	$17.93	-22.8%	COM	92790C104
SLN	SILENCE THERAPEUTICS PLC	476,200	$9.048M	2.0%	$21.60	—	ADS	82686Q101
ANAB	ANAPTYSBIO INC	357,733	$8.965M	2.0%	$28.24	-17.6%	COM	032724106
GHRS	GH RESEARCH PLC	572,665	$6.677M	1.5%	$10.15	+18.3%	ORDINARY SHARES	G3855L106
COGT	COGENT BIOSCIENCES INC	790,440	$6.663M	1.5%	$6.91	+9.7%	COM	19240Q201
—	VOR BIOPHARMA INC	6,361,723	$6.362M	1.4%	$43.10	—	COM	929033108
—	SCPHARMACEUTICALS INC	1,200,647	$5.223M	1.2%	$5.92	—	COM	810648105
—	RALLYBIO CORP	3,630,724	$4.865M	1.1%	$17.58	—	COM	75120L100
QTTB	Q32 BIO INC	251,994	$4.523M	1.0%	$13.78	+73.6%	COM	746964105
—	ADVERUM BIOTECHNOLOGIES INC	541,666	$3.716M	0.8%	$14.14	—	COM NEW	00773U207
—	MERSANA THERAPEUTICS INC	1,305,000	$2.623M	0.6%	$4.03	—	COM	59045L106
ZNTL	ZENTALIS PHARMACEUTICALS INC	490,000	$2.004M	0.4%	$23.99	-53.5%	COM	98943L107
—	CIDARA THERAPEUTICS INC	56,725	$677K	0.2%	$11.94	—	COM	171757206
EYPT	EYEPOINT PHARMACEUTICALS INC	50,000	$435K	0.1%	$13.97	0.0%	COM NEW	30233G209