Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q2 2022 (← Previous) (Next →)
Filing Date: Aug 15, 2022
Total Value: $3.436B (99.6% shares, 0.4% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| HUM | HUMANA INC | 426,358 | $200M | 5.8% | $361.45 | +18.6% | COM | 444859102 |
| AGL | AGILON HEALTH INC | 7,681,000 | $168M | 4.9% | $34.17 | -40.8% | COM | 00857U107 |
| UNH | UNITEDHEALTH GROUP INC | 268,500 | $138M | 4.0% | $219.29 | +114.8% | COM | 91324P102 |
| ARGX | ARGENX SE | 350,000 | $133M | 3.9% | $153.41 | — | SPONSORED ADR | 04016X101 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,122,500 | $109M | 3.2% | $74.96 | +23.1% | COM | 64125C109 |
| PODD | INSULET CORP | 502,000 | $109M | 3.2% | $174.33 | +30.4% | COM | 45784P101 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,671,652 | $99.68M | 2.9% | $41.63 | — | ADS | 45258D105 |
| EVH | EVOLENT HEALTH INC | 2,738,000 | $84.08M | 2.4% | $22.23 | +31.1% | CL A | 30050B101 |
| ALGN | ALIGN TECHNOLOGY INC | 354,500 | $83.9M | 2.4% | $313.91 | -2.1% | COM | 016255101 |
| IDXX | IDEXX LABS INC | 223,750 | $78.48M | 2.3% | $335.38 | +21.6% | COM | 45168D104 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,093,030 | $65.21M | 1.9% | $70.94 | -13.3% | COM | 90400D108 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,928,458 | $64.92M | 1.9% | $41.00 | -44.9% | COM | 00847X104 |
| — | SIERRA ONCOLOGY INC | 1,174,786 | $64.6M | 1.9% | $17.77 | — | COM NEW | 82640U404 |
| ISRG | INTUITIVE SURGICAL INC | 298,500 | $59.91M | 1.7% | $264.69 | -11.4% | COM NEW | 46120E602 |
| — | HORIZON THERAPEUTICS PUB L | 746,000 | $59.5M | 1.7% | $82.74 | — | SHS | G46188101 |
| PCRX | PACIRA BIOSCIENCES INC | 1,017,500 | $59.32M | 1.7% | $48.65 | +34.6% | COM | 695127100 |
| EW | EDWARDS LIFESCIENCES CORP | 602,000 | $57.24M | 1.7% | $60.60 | +70.8% | COM | 28176E108 |
| — | MIRATI THERAPEUTICS INC | 844,977 | $56.72M | 1.7% | $82.06 | — | COM | 60468T105 |
| — | KARUNA THERAPEUTICS INC | 441,893 | $55.9M | 1.6% | $75.86 | — | COM | 48576A100 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,927,149 | $54.82M | 1.6% | $10.84 | +29.3% | COM | 00461U105 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 753,500 | $50.96M | 1.5% | $45.81 | +52.3% | COM | 00404A109 |
| PEN | PENUMBRA INC | 401,500 | $49.99M | 1.5% | $129.25 | +22.8% | COM | 70975L107 |
| — | BLUEPRINT MEDICINES CORP | 979,174 | $49.46M | 1.4% | $71.50 | — | COM | 09627Y109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 332,500 | $48.49M | 1.4% | $95.74 | +48.2% | COM | 02043Q107 |
| — | SEAGEN INC | 272,000 | $48.13M | 1.4% | $173.02 | — | COM | 81181C104 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,767,141 | $46.72M | 1.4% | $22.36 | — | COM | 15678U128 |
| — | SHOCKWAVE MED INC | 240,500 | $45.98M | 1.3% | $79.81 | — | COM | 82489T104 |
| BAX | BAXTER INTL INC | 701,600 | $45.06M | 1.3% | $72.28 | -8.1% | COM | 071813109 |
| ZLAB | ZAI LAB LTD | 1,215,900 | $42.17M | 1.2% | $61.65 | — | ADR | 98887Q104 |
| ASND | ASCENDIS PHARMA A/S | 425,500 | $39.55M | 1.2% | $85.24 | — | SPONSORED ADR | 04351P101 |
| DXCM | DEXCOM INC | 472,800 | $35.24M | 1.0% | $94.67 | -3.6% | COM | 252131107 |
| — | COVETRUS INC | 1,678,800 | $34.84M | 1.0% | $21.18 | — | COM | 22304C100 |
| XENE | XENON PHARMACEUTICALS INC | 1,123,604 | $34.18M | 1.0% | $22.01 | +37.4% | COM | 98420N105 |
| — | NEVRO CORP | 773,300 | $33.89M | 1.0% | $97.62 | — | COM | 64157F103 |
| WST | WEST PHARMACEUTICAL SVSC INC | 111,000 | $33.56M | 1.0% | $294.05 | +9.6% | COM | 955306105 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,717,733 | $33.43M | 1.0% | $13.79 | +71.1% | COM | 604749101 |
| FRPT | FRESHPET INC | 637,600 | $33.09M | 1.0% | $62.04 | +24.3% | COM | 358039105 |
| PHR | PHREESIA INC | 1,298,200 | $32.47M | 0.9% | $28.73 | -23.3% | COM | 71944F106 |
| SRPT | SAREPTA THERAPEUTICS INC | 428,000 | $32.08M | 0.9% | $60.98 | +20.6% | COM | 803607100 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 270,000 | $29.17M | 0.8% | $55.70 | +137.8% | COM | 450056106 |
| XLV | SELECT SECTOR SPDR TR | 200,000 | $25.65M | 0.7% | $128.24 | — | SBI HEALTHCARE | 81369Y209 |
| NVAX | NOVAVAX INC | 475,100 | $24.43M | 0.7% | $43.43 | +19.1% | COM NEW | 670002401 |
| — | ABCAM PLC | 1,620,500 | $23.43M | 0.7% | $20.21 | — | ADS | 000380204 |
| TVTX | TRAVERE THERAPEUTICS INC | 951,650 | $23.06M | 0.7% | $24.60 | +2.2% | COM | 89422G107 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 317,485 | $22.73M | 0.7% | $47.33 | +55.3% | COM | 558868105 |
| EXAS | EXACT SCIENCES CORP | 572,700 | $22.56M | 0.7% | $56.53 | -5.4% | COM | 30063P105 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 264,500 | $21.92M | 0.6% | $85.70 | -7.1% | COM | 09061G101 |
| CNMD | CONMED CORP | 223,000 | $21.35M | 0.6% | $115.02 | +0.8% | COM | 207410101 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,681,458 | $21.17M | 0.6% | $7.76 | — | COM NEW | 268158201 |
| — | TURNING POINT THERAPEUTICS I | 271,787 | $20.45M | 0.6% | $75.25 | — | COM | 90041T108 |
| LEGN | LEGEND BIOTECH CORP | 355,567 | $19.56M | 0.6% | $39.86 | — | SPONSORED ADS | 52490G102 |
| — | CINCOR PHARMA INC | 1,021,159 | $19.24M | 0.6% | $17.54 | — | COM | 17240Y109 |
| — | MERSANA THERAPEUTICS INC | 4,075,958 | $18.83M | 0.5% | $13.04 | — | COM | 59045L106 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 974,107 | $18.76M | 0.5% | $22.45 | -47.1% | COM | 03237H101 |
| — | OLINK HLDG AB | 1,231,800 | $18.72M | 0.5% | $23.90 | — | SPONSORED ADS | 680710100 |
| PRTA | PROTHENA CORP PLC | 678,462 | $18.42M | 0.5% | $12.70 | +130.3% | SHS | G72800108 |
| — | PROMETHEUS BIOSCIENCES INC | 644,507 | $18.19M | 0.5% | $19.18 | — | COM | 74349U108 |
| — | ACCOLADE INC | 2,200,000 | $16.28M | 0.5% | $25.79 | — | COM | 00437E102 |
| CYTK | CYTOKINETICS INC | 400,000 | $15.72M | 0.5% | $40.26 | 0.0% | COM NEW | 23282W605 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1,461,091 | $15.46M | 0.4% | $10.32 | 0.0% | COM | 09058V103 |
| KYMR | KYMERA THERAPEUTICS INC | 775,879 | $15.28M | 0.4% | $34.64 | -32.6% | COM | 501575104 |
| WRBY | WARBY PARKER INC | 1,273,500 | $14.34M | 0.4% | $42.16 | -52.3% | CL A COM | 93403J106 |
| AURA | AURA BIOSCIENCES INC | 1,008,814 | $14.29M | 0.4% | $17.87 | -7.4% | COM | 05153U107 |
| CMPX | COMPASS THERAPEUTICS INC | 5,328,088 | $14.12M | 0.4% | $3.29 | -34.0% | COM | 20454B104 |
| HCAT | HEALTH CATALYST INC | 945,400 | $13.7M | 0.4% | $34.41 | -50.5% | COM | 42225T107 |
| BMEA | BIOMEA FUSION INC | 1,085,740 | $13.01M | 0.4% | $17.65 | -66.8% | COM | 09077A106 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 725,000 | $12.85M | 0.4% | $15.97 | +5.3% | COM | 19459J104 |
| — | INOZYME PHARMA INC | 2,640,056 | $12.59M | 0.4% | $11.53 | — | COM | 45790W108 |
| NVCR | NOVOCURE LTD | 175,000 | $12.16M | 0.4% | $37.58 | +100.4% | ORD SHS | G6674U108 |
| ARVN | ARVINAS INC | 280,100 | $11.79M | 0.3% | $32.84 | +52.8% | COM | 04335A105 |
| AZTA | AZENTA INC | 162,000 | $11.68M | 0.3% | $74.74 | 0.0% | COM | 114340102 |
| ANAB | ANAPTYSBIO INC | 572,300 | $11.62M | 0.3% | $28.23 | -21.5% | COM | 032724106 |
| LFST | LIFESTANCE HEALTH GROUP INC | 2,000,000 | $11.12M | 0.3% | $23.27 | -67.1% | COM | 53228F101 |
| — | EPIZYME INC | 7,485,543 | $11M | 0.3% | $6.51 | — | COM | 29428V104 |
| FOLD | AMICUS THERAPEUTICS INC | 1,012,506 | $10.87M | 0.3% | $11.49 | -28.3% | COM | 03152W109 |
| RLAY | RELAY THERAPEUTICS INC | 618,267 | $10.36M | 0.3% | $34.51 | -37.9% | COM | 75943R102 |
| LUNG | PULMONX CORP | 702,400 | $10.34M | 0.3% | $48.60 | -57.6% | COM | 745848101 |
| IMTX | IMMATICS N.V | 1,127,970 | $9.825M | 0.3% | $7.91 | 0.0% | SHS | N44445109 |
| — | ORION ACQUISITION CORP | 1,000,000 | $9.81M | 0.3% | $10.00 | — | UNIT 02/19/2026 | 68626A207 |
| — | AMRYT PHARMA PLC | 1,312,625 | $9.175M | 0.3% | $12.05 | — | SPONSORED ADS | 03217L106 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 335,477 | $9.044M | 0.3% | $29.89 | -2.8% | COM NEW | 15117B202 |
| — | CHINOOK THERAPEUTICS INC | 507,512 | $8.876M | 0.3% | $15.86 | — | COM | 16961L106 |
| — | INVITAE CORP | 3,494,721 | $8.527M | 0.2% | $20.06 | — | COM | 46185L103 |
| AUPH | AURINIA PHARMACEUTICALS INC | 815,126 | $8.192M | 0.2% | $14.68 | -23.9% | COM | 05156V102 |
| GH | GUARDANT HEALTH INC | 200,000 | $8.068M | 0.2% | $42.73 | +16.0% | COM | 40131M109 |
| — | KINNATE BIOPHARMA INC | 618,384 | $7.798M | 0.2% | $27.15 | — | COM | 49705R105 |
| — | VERVE THERAPEUTICS INC | 504,037 | $7.702M | 0.2% | $60.25 | — | COM | 92539P101 |
| NKTX | NKARTA INC | 616,277 | $7.593M | 0.2% | $26.66 | -50.8% | COM | 65487U108 |
| — | GOSSAMER BIO INC | 9,573,000 | $7.156M | 0.2% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| MREO | MEREO BIOPHARMA GROUP PLC | 6,230,275 | $6.978M | 0.2% | $2.88 | — | ADS | 589492107 |
| DSGN | DESIGN THERAPEUTICS INC | 460,391 | $6.445M | 0.2% | $26.33 | -48.7% | COM | 25056L103 |
| — | AKERO THERAPEUTICS INC | 679,514 | $6.421M | 0.2% | $22.70 | — | COM | 00973Y108 |
| EDAP | EDAP TMS S A | 910,000 | $6.188M | 0.2% | $7.07 | — | SPONSORED ADR | 268311107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 1,403,298 | $5.824M | 0.2% | $15.08 | -63.7% | COM | 76243J105 |
| — | F-STAR THERAPEUTICS INC | 751,889 | $4.707M | 0.1% | $8.59 | — | COM | 30315R107 |
| — | EQRX INC | 1,000,000 | $4.69M | 0.1% | $4.13 | — | COM | 26886C107 |
| — | ICOSAVAX INC | 761,557 | $4.364M | 0.1% | $28.82 | — | COM | 45114M109 |
| BEAM | BEAM THERAPEUTICS INC | 111,430 | $4.313M | 0.1% | $39.75 | 0.0% | COM | 07373V105 |
| — | LEAP THERAPEUTICS INC | 3,652,947 | $4.201M | 0.1% | $3.92 | — | COM | 52187K101 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,357,544 | $4.008M | 0.1% | $8.15 | — | SPONDS ADR | 00653A107 |
| XLO | XILIO THERAPEUTICS INC | 1,362,878 | $3.98M | 0.1% | $15.36 | -75.4% | COM | 98422T100 |
| — | GAMIDA CELL LTD | 2,175,000 | $3.85M | 0.1% | $4.94 | — | SHS | M47364100 |
| — | PARATEK PHARMACEUTICALS INC | 1,734,037 | $3.347M | 0.1% | $6.08 | — | COM | 699374302 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $3.221M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | BCLS ACQUISITION CORP | 309,000 | $3.059M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | RENEO PHARMACEUTICALS INC | 1,143,185 | $3.029M | 0.1% | $9.31 | — | COM | 75974E103 |
| — | SPRUCE BIOSCIENCES INC | 1,622,689 | $2.823M | 0.1% | $24.10 | — | COM | 85209E109 |
| MGNX | MACROGENICS INC | 954,728 | $2.816M | 0.1% | $21.05 | -75.0% | COM | 556099109 |
| FATE | FATE THERAPEUTICS INC | 110,000 | $2.726M | 0.1% | $89.50 | -69.2% | COM | 31189P102 |
| — | THESEUS PHARMACEUTICALS INC | 437,329 | $2.418M | 0.1% | $12.68 | — | COM | 88369M101 |
| CGEN | COMPUGEN LTD | 1,289,990 | $2.386M | 0.1% | $6.12 | -64.8% | ORD | M25722105 |
| — | JIYA ACQUISITION CORP | 206,200 | $2.037M | 0.1% | $10.30 | — | COM CL A | 47760M102 |
| — | FUSION PHARMACEUTICALS INC | 809,854 | $2.017M | 0.1% | $17.41 | — | COM | 36118A100 |
| PRLD | PRELUDE THERAPEUTICS INC | 368,959 | $1.926M | 0.1% | $29.85 | -83.0% | COM | 74065P101 |
| FULC | FULCRUM THERAPEUTICS INC | 384,590 | $1.884M | 0.1% | $18.95 | -48.4% | COM | 359616109 |
| — | TEMPEST THERAPEUTICS INC | 823,654 | $1.771M | 0.1% | $7.50 | — | COM | 87978U108 |
| — | PHASEBIO PHARMACEUTICALS INC | 2,774,869 | $1.665M | 0.0% | $4.30 | — | COM | 717224109 |
| — | ESSA PHARMA INC | 524,944 | $1.654M | 0.0% | $28.44 | — | COM NEW | 29668H708 |
| — | AEGLEA BIOTHERAPEUTICS INC | 3,072,034 | $1.552M | 0.0% | $4.39 | — | COM | 00773J103 |
| — | ACELRX PHARMACEUTICALS INC | 6,329,202 | $1.546M | 0.0% | $1.08 | — | COM | 00444T100 |
| — | RADIUS HEALTH INC | 1,500,000 | $1.473M | 0.0% | $1.01 | — | NOTE 3.000% 9/0 | 750469AA6 |
| — | THERAVANCE BIOPHARMA INC | 1,500,000 | $1.381M | 0.0% | $1.14 | — | NOTE 3.250%11/0 | 88339KAA0 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.328M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | VIGIL NEUROSCIENCE INC | 471,958 | $1.218M | 0.0% | $7.03 | — | COM | 92673K108 |
| — | VINCERX PHARMA INC | 814,194 | $1.075M | 0.0% | $16.10 | — | COM NEW | 92731L106 |
| — | IMARA INC | 842,402 | $1.028M | 0.0% | $4.05 | — | COM | 45249V107 |
| — | ATRECA INC | 462,530 | $828K | 0.0% | $13.90 | — | CL A COM | 04965G109 |
| — | APPLIED THERAPEUTICS INC | 701,680 | $665K | 0.0% | $31.74 | — | COM | 03828A101 |
| SPRO | SPERO THERAPEUTICS INC | 770,710 | $571K | 0.0% | $11.75 | -75.2% | COM | 84833T103 |
| — | NEVRO CORP | 500,000 | $466K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NUVATION BIO INC | 134,028 | $38,000 | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |