Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q2 2015 (← Previous) (Next →)

Filing Date: Aug 14, 2015

Total Value: $2.249B (100.0% shares, 0.0% debt)

Holdings (45)

UTHR UNITED THERAPEUTICS CORP DEL 11.1%
Value $250M Shares 1,439,928 Share Price $173.95 * Est. Cost/Share $77.14 Unrealized @ Report Date +133.2%
— ANACOR PHARMACEUTICALS INC 10.7%
Value $240M Shares 3,103,027 Share Price $77.43 Est. Cost/Share $23.70 Unrealized @ Report Date —
BMRN BIOMARIN PHARMACEUTICAL INC 10.1%
Value $227M Shares 1,660,092 Share Price $136.78 * Est. Cost/Share $73.11 Unrealized @ Report Date +69.5%
— CLOVIS ONCOLOGY INC 9.4%
Value $211M Shares 2,401,117 Share Price $87.88 Est. Cost/Share $51.97 Unrealized @ Report Date —
— ABIOMED INC 8.0%
Value $180M Shares 2,742,305 Share Price $65.73 Est. Cost/Share $26.14 Unrealized @ Report Date —
— AMAG PHARMACEUTICALS INC 6.7%
Value $151M Shares 2,192,141 Share Price $69.06 Est. Cost/Share $28.67 Unrealized @ Report Date —
INSM INSMED INC 5.1%
Value $116M Shares 4,733,601 Share Price $24.42 * Est. Cost/Share $14.79 Unrealized @ Report Date +53.5%
— THORATEC CORP 5.1%
Value $114M Shares 2,560,303 Share Price $44.57 Est. Cost/Share $40.89 Unrealized @ Report Date —
— KYTHERA BIOPHARMACEUTICALS I 4.3%
Value $97.17M Shares 1,290,292 Share Price $75.31 Est. Cost/Share $40.00 Unrealized @ Report Date —
— ENDO INTL PLC 3.1%
Value $68.87M Shares 864,604 Share Price $79.65 Est. Cost/Share $89.70 Unrealized @ Report Date —
— WRIGHT MED GROUP INC 2.4%
Value $54M Shares 2,056,251 Share Price $26.26 Est. Cost/Share $28.27 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 2.2%
Value $49.46M Shares 3,897,408 Share Price $12.69 * Est. Cost/Share $8.39 Unrealized @ Report Date +28.6%
— KARYOPHARM THERAPEUTICS INC 2.1%
Value $47.12M Shares 1,731,530 Share Price $27.21 Est. Cost/Share $29.08 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 1.6%
Value $36.65M Shares 695,918 Share Price $52.67 * Est. Cost/Share $22.18 Unrealized @ Report Date +77.9%
GILD GILEAD SCIENCES INC 1.6%
Value $35.06M Shares 299,500 Share Price $117.08 * Est. Cost/Share $62.40 Unrealized @ Report Date +21.8%
— MOMENTA PHARMACEUTICALS INC 1.5%
Value $33.19M Shares 1,455,176 Share Price $22.81 Est. Cost/Share $14.44 Unrealized @ Report Date —
— SEQUENOM INC 1.4%
Value $30.47M Shares 10,023,842 Share Price $3.04 Est. Cost/Share $3.91 Unrealized @ Report Date —
— CELGENE CORP 1.3%
Value $30.35M Shares 262,200 Share Price $115.74 Est. Cost/Share $96.77 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.2%
Value $27.94M Shares 1,974,376 Share Price $14.15 * Est. Cost/Share $3.07 Unrealized @ Report Date +291.2%
STAA STAAR SURGICAL CO 1.1%
Value $25.53M Shares 2,642,922 Share Price $9.66 * Est. Cost/Share $8.11 Unrealized @ Report Date +14.3%
— CYBERONICS INC 1.1%
Value $24.5M Shares 412,000 Share Price $59.46 Est. Cost/Share $52.15 Unrealized @ Report Date —
— SHIRE PLC 1.1%
Value $23.74M Shares 98,300 Share Price $241.49 Est. Cost/Share $229.35 Unrealized @ Report Date —
— MEDIVATION INC 0.9%
Value $20.59M Shares 180,300 Share Price $114.20 Est. Cost/Share $86.62 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 0.8%
Value $18.46M Shares 2,231,717 Share Price $8.27 Est. Cost/Share $6.82 Unrealized @ Report Date —
— HEARTWARE INTL INC 0.8%
Value $17.73M Shares 243,868 Share Price $72.69 Est. Cost/Share $87.77 Unrealized @ Report Date —
— ZELTIQ AESTHETICS INC 0.7%
Value $16.75M Shares 568,436 Share Price $29.47 Est. Cost/Share $26.16 Unrealized @ Report Date —
— RIGEL PHARMACEUTICALS INC 0.7%
Value $16.62M Shares 5,176,319 Share Price $3.21 Est. Cost/Share $3.43 Unrealized @ Report Date —
ISRG INTUITIVE SURGICAL INC 0.7%
Value $15.67M Shares 32,350 Share Price $484.51 * Est. Cost/Share $55.94 Unrealized @ Report Date 0.0%
— ALIMERA SCIENCES INC 0.6%
Value $13.89M Shares 3,013,793 Share Price $4.61 Est. Cost/Share $4.88 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.5%
Value $11.68M Shares 392,676 Share Price $29.74 * Est. Cost/Share $12.83 Unrealized @ Report Date +95.8%
— OREXIGEN THERAPEUTICS INC 0.4%
Value $9.56M Shares 1,931,324 Share Price $4.95 Est. Cost/Share $6.46 Unrealized @ Report Date —
— ACELRX PHARMACEUTICALS INC 0.4%
Value $9.056M Shares 2,135,739 Share Price $4.24 Est. Cost/Share $5.78 Unrealized @ Report Date —
— IDERA PHARMACEUTICALS INC 0.2%
Value $4.551M Shares 1,226,748 Share Price $3.71 Est. Cost/Share $3.71 Unrealized @ Report Date —
— XOMA CORP DEL 0.1%
Value $3.1M Shares 799,000 Share Price $3.88 Est. Cost/Share $4.07 Unrealized @ Report Date —
— HISTOGENICS CORP 0.1%
Value $2.936M Shares 454,545 Share Price $6.46 Est. Cost/Share $11.00 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.1%
Value $2.728M Shares 906,263 Share Price $3.01 Est. Cost/Share $2.64 Unrealized @ Report Date —
— BIOSPECIFICS TECHNOLOGIES CO 0.1%
Value $2.602M Shares 50,436 Share Price $51.59 Est. Cost/Share $34.45 Unrealized @ Report Date —
— INTREXON CORP 0.1%
Value $2.298M Shares 47,100 Share Price $48.79 Est. Cost/Share $28.82 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.1%
Value $1.741M Shares 27,757 Share Price $62.72 * Est. Cost/Share $53.35 Unrealized @ Report Date +10.7%
— EPIZYME INC 0.1%
Value $1.47M Shares 61,265 Share Price $23.99 Est. Cost/Share $23.99 Unrealized @ Report Date —
— ALCOBRA LTD 0.0%
Value $1.024M Shares 156,588 Share Price $6.54 Est. Cost/Share $6.11 Unrealized @ Report Date —
— DICERNA PHARMACEUTICALS INC 0.0%
Value $986K Shares 70,706 Share Price $13.95 Est. Cost/Share $13.95 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.0%
Value $831K Shares 123,686 Share Price $6.72 * Est. Cost/Share $6.71 Unrealized @ Report Date -2.3%
— MALLINCKRODT PUB LTD CO 0.0%
Value $422K Shares 3,588 Share Price $117.61 Est. Cost/Share $90.02 Unrealized @ Report Date —
— SOPHIRIS BIO INC 0.0%
Value $150K Shares 191,600 Share Price $0.78 Est. Cost/Share $3.88 Unrealized @ Report Date —