Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q1 2015 (← Previous) (Next →)

Filing Date: May 15, 2015

Total Value: $2.023B (100.0% shares, 0.0% debt)

Holdings (46)

UTHR UNITED THERAPEUTICS CORP DEL 12.2%
Value $247M Shares 1,429,928 Share Price $172.44 * Est. Cost/Share $77.14 Unrealized @ Report Date +97.6%
BMRN BIOMARIN PHARMACEUTICAL INC 10.2%
Value $206M Shares 1,649,792 Share Price $124.62 * Est. Cost/Share $73.11 Unrealized @ Report Date +44.9%
— ANACOR PHARMACEUTICALS INC 9.3%
Value $189M Shares 3,259,045 Share Price $57.85 Est. Cost/Share $23.70 Unrealized @ Report Date —
— ABIOMED INC 8.8%
Value $177M Shares 2,473,624 Share Price $71.58 Est. Cost/Share $21.84 Unrealized @ Report Date —
— CLOVIS ONCOLOGY INC 7.8%
Value $158M Shares 2,121,857 Share Price $74.23 Est. Cost/Share $47.24 Unrealized @ Report Date —
— AMAG PHARMACEUTICALS INC 5.9%
Value $120M Shares 2,187,041 Share Price $54.66 Est. Cost/Share $28.67 Unrealized @ Report Date —
— THORATEC CORP 5.3%
Value $106M Shares 2,538,203 Share Price $41.89 Est. Cost/Share $40.89 Unrealized @ Report Date —
INSM INSMED INC 4.8%
Value $96.71M Shares 4,649,448 Share Price $20.80 * Est. Cost/Share $14.64 Unrealized @ Report Date +20.3%
— ENDO INTL PLC 3.8%
Value $77.16M Shares 860,204 Share Price $89.70 Est. Cost/Share $89.70 Unrealized @ Report Date —
— KYTHERA BIOPHARMACEUTICALS I 3.4%
Value $69.34M Shares 1,382,722 Share Price $50.15 Est. Cost/Share $40.00 Unrealized @ Report Date —
— WRIGHT MED GROUP INC 2.6%
Value $52.87M Shares 2,049,251 Share Price $25.80 Est. Cost/Share $28.27 Unrealized @ Report Date —
— SEQUENOM INC 1.9%
Value $39.41M Shares 9,977,642 Share Price $3.95 Est. Cost/Share $3.91 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 1.7%
Value $35.37M Shares 3,803,408 Share Price $9.30 * Est. Cost/Share $8.33 Unrealized @ Report Date +35.7%
— KARYOPHARM THERAPEUTICS INC 1.4%
Value $29.11M Shares 951,032 Share Price $30.61 Est. Cost/Share $30.61 Unrealized @ Report Date —
— CELGENE CORP 1.4%
Value $28.75M Shares 249,400 Share Price $115.28 Est. Cost/Share $95.80 Unrealized @ Report Date —
GILD GILEAD SCIENCES INC 1.4%
Value $28.56M Shares 291,000 Share Price $98.13 * Est. Cost/Share $62.00 Unrealized @ Report Date +13.8%
— CELLADON CORP 1.4%
Value $27.37M Shares 1,445,100 Share Price $18.94 Est. Cost/Share $12.12 Unrealized @ Report Date —
— CYBERONICS INC 1.3%
Value $26.75M Shares 412,000 Share Price $64.92 Est. Cost/Share $52.15 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 1.3%
Value $26.54M Shares 695,918 Share Price $38.14 * Est. Cost/Share $22.18 Unrealized @ Report Date +15.6%
— SHIRE PLC 1.1%
Value $22.73M Shares 95,000 Share Price $239.29 Est. Cost/Share $228.93 Unrealized @ Report Date —
— MEDIVATION INC 1.1%
Value $22.16M Shares 171,700 Share Price $129.07 Est. Cost/Share $85.24 Unrealized @ Report Date —
— MOMENTA PHARMACEUTICALS INC 1.1%
Value $22.12M Shares 1,455,176 Share Price $15.20 Est. Cost/Share $14.44 Unrealized @ Report Date —
— HEARTWARE INTL INC 1.1%
Value $21.4M Shares 243,868 Share Price $87.77 Est. Cost/Share $87.77 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.1%
Value $21.29M Shares 1,956,376 Share Price $10.88 * Est. Cost/Share $3.07 Unrealized @ Report Date +186.8%
STAA STAAR SURGICAL CO 1.0%
Value $19.64M Shares 2,642,922 Share Price $7.43 Est. Cost/Share $8.11 Unrealized @ Report Date -9.9%
— RIGEL PHARMACEUTICALS INC 0.9%
Value $18.48M Shares 5,176,319 Share Price $3.57 Est. Cost/Share $3.43 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 0.9%
Value $18.39M Shares 2,231,717 Share Price $8.24 Est. Cost/Share $6.82 Unrealized @ Report Date —
— ZELTIQ AESTHETICS INC 0.9%
Value $17.52M Shares 568,436 Share Price $30.83 Est. Cost/Share $26.16 Unrealized @ Report Date —
— INTUITIVE SURGICAL INC 0.8%
Value $16.34M Shares 32,350 Share Price $505.04 Est. Cost/Share $447.59 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.7%
Value $15.17M Shares 282,057 Share Price $53.78 * Est. Cost/Share $53.35 Unrealized @ Report Date +6.8%
— OREXIGEN THERAPEUTICS INC 0.7%
Value $15.12M Shares 1,931,324 Share Price $7.83 Est. Cost/Share $6.46 Unrealized @ Report Date —
— ALIMERA SCIENCES INC 0.7%
Value $15.1M Shares 3,013,793 Share Price $5.01 Est. Cost/Share $4.88 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.4%
Value $8.647M Shares 392,676 Share Price $22.02 * Est. Cost/Share $12.83 Unrealized @ Report Date +97.7%
— ACELRX PHARMACEUTICALS INC 0.4%
Value $8.244M Shares 2,135,739 Share Price $3.86 Est. Cost/Share $5.78 Unrealized @ Report Date —
— HISTOGENICS CORP 0.2%
Value $4.541M Shares 454,545 Share Price $9.99 Est. Cost/Share $11.00 Unrealized @ Report Date —
— IDERA PHARMACEUTICALS INC 0.2%
Value $4.342M Shares 1,170,248 Share Price $3.71 Est. Cost/Share $3.71 Unrealized @ Report Date —
— XOMA CORP DEL 0.1%
Value $2.892M Shares 794,500 Share Price $3.64 Est. Cost/Share $4.07 Unrealized @ Report Date —
— INTREXON CORP 0.1%
Value $2.137M Shares 47,100 Share Price $45.37 Est. Cost/Share $28.82 Unrealized @ Report Date —
— BIOSPECIFICS TECHNOLOGIES CO 0.1%
Value $1.975M Shares 50,436 Share Price $39.16 Est. Cost/Share $34.45 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.1%
Value $1.478M Shares 603,400 Share Price $2.45 Est. Cost/Share $2.45 Unrealized @ Report Date —
— QLT INC 0.1%
Value $1.235M Shares 315,906 Share Price $3.91 Est. Cost/Share $4.40 Unrealized @ Report Date —
— SALIX PHARMACEUTICALS INC 0.0%
Value $916K Shares 5,300 Share Price $172.83 Est. Cost/Share $114.94 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.0%
Value $839K Shares 123,686 Share Price $6.78 * Est. Cost/Share $6.71 Unrealized @ Report Date +11.2%
— MALLINCKRODT PUB LTD CO 0.0%
Value $454K Shares 3,588 Share Price $126.53 Est. Cost/Share $90.02 Unrealized @ Report Date —
— ALCOBRA LTD 0.0%
Value $412K Shares 73,188 Share Price $5.63 Est. Cost/Share $5.63 Unrealized @ Report Date —
— SOPHIRIS BIO INC 0.0%
Value $111K Shares 191,600 Share Price $0.58 Est. Cost/Share $3.88 Unrealized @ Report Date —