Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value: $1.797B (100.0% shares, 0.0% debt)

Holdings (43)

— ABIOMED INC 14.5%
Value $261M Shares 2,889,505 Share Price $90.28 Est. Cost/Share $29.48 Unrealized @ Report Date —
— ANACOR PHARMACEUTICALS INC 13.8%
Value $247M Shares 2,187,242 Share Price $112.97 Est. Cost/Share $23.70 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP DEL 13.2%
Value $238M Shares 1,518,654 Share Price $156.61 * Est. Cost/Share $81.75 Unrealized @ Report Date +78.1%
BMRN BIOMARIN PHARMACEUTICAL INC 7.8%
Value $140M Shares 1,336,847 Share Price $104.76 Est. Cost/Share $73.11 Unrealized @ Report Date +42.7%
— CLOVIS ONCOLOGY INC 6.9%
Value $124M Shares 3,547,719 Share Price $35.00 Est. Cost/Share $57.85 Unrealized @ Report Date —
INSM INSMED INC 4.8%
Value $86.95M Shares 4,790,800 Share Price $18.15 * Est. Cost/Share $14.79 Unrealized @ Report Date +19.1%
— AMAG PHARMACEUTICALS INC 4.8%
Value $85.61M Shares 2,835,792 Share Price $30.19 Est. Cost/Share $30.99 Unrealized @ Report Date —
— WRIGHT MED GROUP N V 2.9%
Value $51.56M Shares 2,132,157 Share Price $24.18 Est. Cost/Share $24.18 Unrealized @ Report Date —
— ENDO INTL PLC 2.7%
Value $49.05M Shares 801,230 Share Price $61.22 Est. Cost/Share $89.70 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 2.6%
Value $47.37M Shares 695,518 Share Price $68.11 * Est. Cost/Share $22.18 Unrealized @ Report Date +171.9%
— EPIZYME INC 2.4%
Value $42.63M Shares 2,660,979 Share Price $16.02 Est. Cost/Share $13.76 Unrealized @ Report Date —
— KARYOPHARM THERAPEUTICS INC 2.3%
Value $41.24M Shares 3,112,645 Share Price $13.25 Est. Cost/Share $20.94 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 2.1%
Value $37.53M Shares 4,030,908 Share Price $9.31 * Est. Cost/Share $8.48 Unrealized @ Report Date +17.7%
— CEMPRA INC 2.0%
Value $36.6M Shares 1,175,733 Share Price $31.13 Est. Cost/Share $31.13 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.9%
Value $34.45M Shares 3,551,173 Share Price $9.70 * Est. Cost/Share $5.71 Unrealized @ Report Date +57.8%
— CELGENE CORP 1.8%
Value $32.43M Shares 270,800 Share Price $119.76 Est. Cost/Share $97.13 Unrealized @ Report Date —
GILD GILEAD SCIENCES INC 1.7%
Value $30.65M Shares 302,900 Share Price $101.19 * Est. Cost/Share $63.23 Unrealized @ Report Date +15.3%
— MEDIVATION INC 1.4%
Value $24.65M Shares 509,862 Share Price $48.34 Est. Cost/Share $58.10 Unrealized @ Report Date —
— MOMENTA PHARMACEUTICALS INC 1.2%
Value $21.8M Shares 1,468,776 Share Price $14.84 Est. Cost/Share $14.44 Unrealized @ Report Date —
— SHIRE PLC 1.2%
Value $21.46M Shares 104,700 Share Price $205.00 Est. Cost/Share $227.87 Unrealized @ Report Date —
STAA STAAR SURGICAL CO 1.1%
Value $19.04M Shares 2,666,722 Share Price $7.14 * Est. Cost/Share $8.11 Unrealized @ Report Date -0.1%
— SEQUENOM INC 0.9%
Value $16.44M Shares 10,023,842 Share Price $1.64 Est. Cost/Share $3.91 Unrealized @ Report Date —
— ZELTIQ AESTHETICS INC 0.9%
Value $16.37M Shares 573,636 Share Price $28.53 Est. Cost/Share $26.16 Unrealized @ Report Date —
— RIGEL PHARMACEUTICALS INC 0.9%
Value $15.88M Shares 5,239,119 Share Price $3.03 Est. Cost/Share $3.43 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 0.8%
Value $14.11M Shares 2,257,217 Share Price $6.25 Est. Cost/Share $6.81 Unrealized @ Report Date —
— HEARTWARE INTL INC 0.7%
Value $12.4M Shares 246,068 Share Price $50.40 Est. Cost/Share $87.77 Unrealized @ Report Date —
— ALIMERA SCIENCES INC 0.4%
Value $7.293M Shares 3,013,793 Share Price $2.42 Est. Cost/Share $4.88 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.3%
Value $6.26M Shares 6,974,854 Share Price $0.90 Est. Cost/Share $1.05 Unrealized @ Report Date —
— AIMMUNE THERAPEUTICS INC 0.3%
Value $6.007M Shares 325,599 Share Price $18.45 Est. Cost/Share $25.32 Unrealized @ Report Date —
— ACELRX PHARMACEUTICALS INC 0.3%
Value $5.488M Shares 1,425,439 Share Price $3.85 Est. Cost/Share $5.78 Unrealized @ Report Date —
— IDERA PHARMACEUTICALS INC 0.2%
Value $3.886M Shares 1,257,748 Share Price $3.09 Est. Cost/Share $3.70 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.2%
Value $3.658M Shares 396,276 Share Price $9.23 Est. Cost/Share $12.83 Unrealized @ Report Date -27.5%
— DICERNA PHARMACEUTICALS INC 0.2%
Value $3.18M Shares 267,890 Share Price $11.87 Est. Cost/Share $9.72 Unrealized @ Report Date —
— OREXIGEN THERAPEUTICS INC 0.2%
Value $2.878M Shares 1,673,024 Share Price $1.72 Est. Cost/Share $6.46 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.1%
Value $1.828M Shares 27,757 Share Price $65.86 * Est. Cost/Share $53.35 Unrealized @ Report Date +20.3%
— ALCOBRA LTD 0.1%
Value $1.596M Shares 254,188 Share Price $6.28 Est. Cost/Share $6.09 Unrealized @ Report Date —
— HISTOGENICS CORP 0.1%
Value $1.591M Shares 454,545 Share Price $3.50 Est. Cost/Share $11.00 Unrealized @ Report Date —
— INTREXON CORP 0.1%
Value $1.42M Shares 47,100 Share Price $30.15 Est. Cost/Share $28.82 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.1%
Value $1.294M Shares 123,686 Share Price $10.46 * Est. Cost/Share $6.71 Unrealized @ Report Date +46.1%
— SOPHIRIS BIO INC 0.0%
Value $879K Shares 494,000 Share Price $1.78 Est. Cost/Share $2.60 Unrealized @ Report Date —
— MARINUS PHARMACEUTICALS INC 0.0%
Value $451K Shares 59,017 Share Price $7.64 Est. Cost/Share $8.34 Unrealized @ Report Date —
— ZOGENIX INC 0.0%
Value $422K Shares 28,600 Share Price $14.76 Est. Cost/Share $13.52 Unrealized @ Report Date —
QURE UNIQURE NV 0.0%
Value $338K Shares 20,453 Share Price $16.53 * Est. Cost/Share $26.34 Unrealized @ Report Date -29.7%