Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q3 2016 (← Previous) (Next →)

Filing Date: Nov 14, 2016

Total Value: $1.722B (100.0% shares, 0.0% debt)

Holdings (42)

— ABIOMED INC 14.1%
Value $242M Shares 1,884,384 Share Price $128.58 Est. Cost/Share $29.48 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP DEL 12.1%
Value $208M Shares 1,763,458 Share Price $118.08 Est. Cost/Share $85.99 Unrealized @ Report Date +39.7%
BMRN BIOMARIN PHARMACEUTICAL INC 9.6%
Value $166M Shares 1,790,899 Share Price $92.52 Est. Cost/Share $76.38 Unrealized @ Report Date +23.3%
— CLOVIS ONCOLOGY INC 8.0%
Value $137M Shares 3,804,088 Share Price $36.05 Est. Cost/Share $53.87 Unrealized @ Report Date —
— AMAG PHARMACEUTICALS INC 4.7%
Value $81.54M Shares 3,326,720 Share Price $24.51 Est. Cost/Share $29.94 Unrealized @ Report Date —
INSM INSMED INC 4.3%
Value $73.93M Shares 5,091,298 Share Price $14.52 * Est. Cost/Share $14.63 Unrealized @ Report Date -14.4%
— CEMPRA INC 4.0%
Value $68.84M Shares 2,844,483 Share Price $24.20 Est. Cost/Share $22.71 Unrealized @ Report Date —
— ALEXION PHARMACEUTICALS INC 4.0%
Value $68.83M Shares 561,700 Share Price $122.54 Est. Cost/Share $119.05 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 4.0%
Value $68.4M Shares 4,110,708 Share Price $16.64 * Est. Cost/Share $8.54 Unrealized @ Report Date +57.7%
— WRIGHT MED GROUP N V 3.5%
Value $59.87M Shares 2,440,493 Share Price $24.53 Est. Cost/Share $23.40 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 3.3%
Value $56.04M Shares 934,455 Share Price $59.97 * Est. Cost/Share $29.22 Unrealized @ Report Date +83.6%
— ZELTIQ AESTHETICS INC 3.2%
Value $55.48M Shares 1,414,563 Share Price $39.22 Est. Cost/Share $27.05 Unrealized @ Report Date —
ACAD ACADIA PHARMACEUTICALS INC 2.7%
Value $47.14M Shares 1,481,930 Share Price $31.81 * Est. Cost/Share $29.67 Unrealized @ Report Date +14.3%
FOLD AMICUS THERAPEUTICS INC 2.4%
Value $42.07M Shares 5,685,388 Share Price $7.40 * Est. Cost/Share $6.12 Unrealized @ Report Date +10.3%
— SAGE THERAPEUTICS INC 2.4%
Value $41.54M Shares 902,051 Share Price $46.05 Est. Cost/Share $38.68 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 2.1%
Value $35.42M Shares 2,587,617 Share Price $13.69 Est. Cost/Share $7.02 Unrealized @ Report Date —
— CELGENE CORP 1.8%
Value $30.6M Shares 292,700 Share Price $104.53 Est. Cost/Share $97.51 Unrealized @ Report Date —
STAA STAAR SURGICAL CO 1.8%
Value $30.5M Shares 3,244,610 Share Price $9.40 * Est. Cost/Share $7.82 Unrealized @ Report Date +2.7%
— KARYOPHARM THERAPEUTICS INC 1.7%
Value $30.02M Shares 3,085,849 Share Price $9.73 Est. Cost/Share $20.75 Unrealized @ Report Date —
— EPIZYME INC 1.6%
Value $27.7M Shares 2,814,540 Share Price $9.84 Est. Cost/Share $13.55 Unrealized @ Report Date —
GILD GILEAD SCIENCES INC 1.5%
Value $25.19M Shares 318,400 Share Price $79.12 * Est. Cost/Share $63.20 Unrealized @ Report Date -8.6%
— SHIRE PLC 1.4%
Value $23.88M Shares 123,200 Share Price $193.86 Est. Cost/Share $221.47 Unrealized @ Report Date —
— MOMENTA PHARMACEUTICALS INC 1.1%
Value $19.3M Shares 1,650,876 Share Price $11.69 Est. Cost/Share $14.05 Unrealized @ Report Date —
— ENDO INTL PLC 1.1%
Value $19.05M Shares 945,330 Share Price $20.15 Est. Cost/Share $78.87 Unrealized @ Report Date —
— RIGEL PHARMACEUTICALS INC 1.1%
Value $19.03M Shares 5,186,088 Share Price $3.67 Est. Cost/Share $3.39 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.4%
Value $7.372M Shares 396,976 Share Price $18.57 * Est. Cost/Share $12.83 Unrealized @ Report Date +37.3%
— ACELRX PHARMACEUTICALS INC 0.4%
Value $6.359M Shares 1,634,608 Share Price $3.89 Est. Cost/Share $5.54 Unrealized @ Report Date —
— AIMMUNE THERAPEUTICS INC 0.3%
Value $5.696M Shares 379,727 Share Price $15.00 Est. Cost/Share $23.85 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.3%
Value $5.08M Shares 1,162,473 Share Price $4.37 Est. Cost/Share $4.37 Unrealized @ Report Date —
— ALIMERA SCIENCES INC 0.3%
Value $4.491M Shares 3,013,793 Share Price $1.49 Est. Cost/Share $4.88 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.2%
Value $3.512M Shares 37,457 Share Price $93.76 * Est. Cost/Share $59.75 Unrealized @ Report Date +51.4%
— IDERA PHARMACEUTICALS INC 0.2%
Value $3.22M Shares 1,257,748 Share Price $2.56 Est. Cost/Share $3.70 Unrealized @ Report Date —
— DICERNA PHARMACEUTICALS INC 0.1%
Value $1.575M Shares 267,890 Share Price $5.88 Est. Cost/Share $9.72 Unrealized @ Report Date —
— HISTOGENICS CORP 0.1%
Value $1.459M Shares 454,545 Share Price $3.21 Est. Cost/Share $11.00 Unrealized @ Report Date —
— INTREXON CORP 0.1%
Value $1.32M Shares 47,100 Share Price $28.03 Est. Cost/Share $28.82 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.1%
Value $1.135M Shares 123,686 Share Price $9.18 * Est. Cost/Share $6.71 Unrealized @ Report Date +55.5%
— SOPHIRIS BIO INC 0.0%
Value $768K Shares 247,000 Share Price $3.11 Est. Cost/Share $2.60 Unrealized @ Report Date —
— ALCOBRA LTD 0.0%
Value $674K Shares 272,788 Share Price $2.47 Est. Cost/Share $5.98 Unrealized @ Report Date —
— OREXIGEN THERAPEUTICS INC 0.0%
Value $555K Shares 167,302 Share Price $3.32 Est. Cost/Share $3.32 Unrealized @ Report Date —
— ZOGENIX INC 0.0%
Value $337K Shares 29,500 Share Price $11.42 Est. Cost/Share $13.36 Unrealized @ Report Date —
QURE UNIQURE NV 0.0%
Value $156K Shares 20,453 Share Price $7.63 * Est. Cost/Share $26.34 Unrealized @ Report Date -69.9%
— MARINUS PHARMACEUTICALS INC 0.0%
Value $116K Shares 63,517 Share Price $1.83 Est. Cost/Share $7.84 Unrealized @ Report Date —