Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q2 2016 (← Previous) (Next →)

Filing Date: Aug 16, 2016

Total Value: $1.324B (100.0% shares, 0.0% debt)

Holdings (45)

— ABIOMED INC 17.1%
Value $226M Shares 2,066,919 Share Price $109.29 Est. Cost/Share $29.48 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP DEL 13.8%
Value $182M Shares 1,718,658 Share Price $105.92 * Est. Cost/Share $85.10 Unrealized @ Report Date +31.1%
BMRN BIOMARIN PHARMACEUTICAL INC 10.2%
Value $135M Shares 1,737,399 Share Price $77.80 * Est. Cost/Share $75.83 Unrealized @ Report Date +12.1%
— AMAG PHARMACEUTICALS INC 5.9%
Value $78.3M Shares 3,273,220 Share Price $23.92 Est. Cost/Share $30.03 Unrealized @ Report Date —
— CLOVIS ONCOLOGY INC 3.9%
Value $52.19M Shares 3,804,088 Share Price $13.72 Est. Cost/Share $53.87 Unrealized @ Report Date —
INSM INSMED INC 3.8%
Value $49.84M Shares 5,054,713 Share Price $9.86 * Est. Cost/Share $14.63 Unrealized @ Report Date -20.2%
VNDA VANDA PHARMACEUTICALS INC 3.6%
Value $47.28M Shares 4,225,608 Share Price $11.19 * Est. Cost/Share $8.54 Unrealized @ Report Date +13.4%
ACAD ACADIA PHARMACEUTICALS INC 3.5%
Value $46.67M Shares 1,437,730 Share Price $32.46 * Est. Cost/Share $29.54 Unrealized @ Report Date +13.3%
— CEMPRA INC 3.5%
Value $45.97M Shares 2,787,542 Share Price $16.49 Est. Cost/Share $22.68 Unrealized @ Report Date —
— WRIGHT MED GROUP N V 3.2%
Value $41.83M Shares 2,408,393 Share Price $17.37 Est. Cost/Share $23.38 Unrealized @ Report Date —
— ALEXION PHARMACEUTICALS INC 3.0%
Value $39.63M Shares 339,400 Share Price $116.76 Est. Cost/Share $116.76 Unrealized @ Report Date —
— ZELTIQ AESTHETICS INC 2.9%
Value $38.02M Shares 1,391,079 Share Price $27.33 Est. Cost/Share $26.85 Unrealized @ Report Date —
— EPIZYME INC 2.1%
Value $27.77M Shares 2,711,381 Share Price $10.24 Est. Cost/Share $13.69 Unrealized @ Report Date —
— CELGENE CORP 2.1%
Value $27.58M Shares 279,600 Share Price $98.63 Est. Cost/Share $97.18 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 2.1%
Value $27.57M Shares 788,618 Share Price $34.96 * Est. Cost/Share $24.71 Unrealized @ Report Date +76.3%
GILD GILEAD SCIENCES INC 2.0%
Value $26.56M Shares 318,400 Share Price $83.42 * Est. Cost/Share $63.20 Unrealized @ Report Date -0.7%
— SHIRE PLC 1.7%
Value $21.96M Shares 119,300 Share Price $184.08 Est. Cost/Share $222.37 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.7%
Value $21.89M Shares 4,009,375 Share Price $5.46 * Est. Cost/Share $5.86 Unrealized @ Report Date +19.4%
— KARYOPHARM THERAPEUTICS INC 1.6%
Value $21.07M Shares 3,139,433 Share Price $6.71 Est. Cost/Share $20.75 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 1.4%
Value $18.73M Shares 2,535,117 Share Price $7.39 Est. Cost/Share $6.88 Unrealized @ Report Date —
STAA STAAR SURGICAL CO 1.3%
Value $17.67M Shares 3,207,210 Share Price $5.51 * Est. Cost/Share $7.82 Unrealized @ Report Date -17.4%
— MOMENTA PHARMACEUTICALS INC 1.3%
Value $17.59M Shares 1,629,076 Share Price $10.80 Est. Cost/Share $14.08 Unrealized @ Report Date —
— MEDIVATION INC 1.2%
Value $16.52M Shares 273,983 Share Price $60.30 Est. Cost/Share $57.74 Unrealized @ Report Date —
— HEARTWARE INTL INC 1.2%
Value $15.77M Shares 272,986 Share Price $57.75 Est. Cost/Share $84.25 Unrealized @ Report Date —
— ENDO INTL PLC 1.1%
Value $14.39M Shares 923,230 Share Price $15.59 Est. Cost/Share $80.28 Unrealized @ Report Date —
— SAGE THERAPEUTICS INC 1.0%
Value $12.59M Shares 417,878 Share Price $30.13 Est. Cost/Share $30.13 Unrealized @ Report Date —
— RIGEL PHARMACEUTICALS INC 0.9%
Value $12.01M Shares 5,386,534 Share Price $2.23 Est. Cost/Share $3.39 Unrealized @ Report Date —
— SEQUENOM INC 0.7%
Value $9.432M Shares 10,322,377 Share Price $0.91 Est. Cost/Share $3.82 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.4%
Value $4.854M Shares 396,276 Share Price $12.25 * Est. Cost/Share $12.83 Unrealized @ Report Date -41.3%
— ACELRX PHARMACEUTICALS INC 0.3%
Value $3.834M Shares 1,425,439 Share Price $2.69 Est. Cost/Share $5.78 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.3%
Value $3.82M Shares 6,974,854 Share Price $0.55 Est. Cost/Share $1.05 Unrealized @ Report Date —
— ALIMERA SCIENCES INC 0.3%
Value $3.707M Shares 3,013,793 Share Price $1.23 Est. Cost/Share $4.88 Unrealized @ Report Date —
— AIMMUNE THERAPEUTICS INC 0.3%
Value $3.523M Shares 325,599 Share Price $10.82 Est. Cost/Share $25.32 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.2%
Value $2.929M Shares 36,357 Share Price $80.56 * Est. Cost/Share $58.82 Unrealized @ Report Date +30.0%
— IDERA PHARMACEUTICALS INC 0.1%
Value $1.924M Shares 1,257,748 Share Price $1.53 Est. Cost/Share $3.70 Unrealized @ Report Date —
— ALCOBRA LTD 0.1%
Value $1.225M Shares 272,788 Share Price $4.49 Est. Cost/Share $5.98 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.1%
Value $1.174M Shares 123,686 Share Price $9.49 * Est. Cost/Share $6.71 Unrealized @ Report Date +22.2%
— INTREXON CORP 0.1%
Value $1.159M Shares 47,100 Share Price $24.61 Est. Cost/Share $28.82 Unrealized @ Report Date —
— SOPHIRIS BIO INC 0.1%
Value $1.062M Shares 494,000 Share Price $2.15 Est. Cost/Share $2.60 Unrealized @ Report Date —
— DICERNA PHARMACEUTICALS INC 0.1%
Value $804K Shares 267,890 Share Price $3.00 Est. Cost/Share $9.72 Unrealized @ Report Date —
— HISTOGENICS CORP 0.1%
Value $777K Shares 454,545 Share Price $1.71 Est. Cost/Share $11.00 Unrealized @ Report Date —
— OREXIGEN THERAPEUTICS INC 0.1%
Value $719K Shares 1,673,024 Share Price $0.43 Est. Cost/Share $6.46 Unrealized @ Report Date —
— ZOGENIX INC 0.0%
Value $237K Shares 29,500 Share Price $8.03 Est. Cost/Share $13.36 Unrealized @ Report Date —
QURE UNIQURE NV 0.0%
Value $151K Shares 20,453 Share Price $7.38 * Est. Cost/Share $26.34 Unrealized @ Report Date -54.6%
— MARINUS PHARMACEUTICALS INC 0.0%
Value $81,000 Shares 63,517 Share Price $1.28 Est. Cost/Share $7.84 Unrealized @ Report Date —