Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q3 2024 (← Previous) (Next →)
Filing Date: Nov 14, 2024
Total Value: $6.911B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,993,687 | $423M | 6.1% | $231.65 | +10.4% | COM | 558868105 |
| AXSM | AXSOME THERAPEUTICS INC | 4,189,557 | $377M | 5.4% | $56.00 | +55.9% | COM | 05464T104 |
| RNAM | AVIDITY BIOSCIENCES INC | 8,132,870 | $374M | 5.4% | $23.99 | +80.9% | COM | 05370A108 |
| ARGX | ARGENX SE | 654,430 | $355M | 5.1% | $344.30 | — | SPONSORED ADR | 04016X101 |
| NTRA | NATERA INC | 2,593,323 | $329M | 4.8% | $42.76 | +168.5% | COM | 632307104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 17,687,772 | $327M | 4.7% | $17.75 | +15.4% | COM | 77313F106 |
| PTCT | PTC THERAPEUTICS INC | 7,393,127 | $274M | 4.0% | $38.04 | -12.0% | COM | 69366J200 |
| DYN | DYNE THERAPEUTICS INC | 6,818,641 | $245M | 3.5% | $26.82 | +48.4% | COM | 26818M108 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 5,426,112 | $244M | 3.5% | $22.45 | +80.0% | COM | 74366E102 |
| BRKR | BRUKER CORP | 3,481,119 | $240M | 3.5% | $72.91 | -12.0% | COM | 116794108 |
| INSM | INSMED INC | 3,272,008 | $239M | 3.5% | $29.56 | +149.7% | COM PAR $.01 | 457669307 |
| ACAD | ACADIA PHARMACEUTICALS INC | 13,707,506 | $211M | 3.1% | $21.38 | -22.0% | COM | 004225108 |
| — | MERUS N V | 4,169,393 | $208M | 3.0% | $34.07 | — | COM | N5749R100 |
| GERN | GERON CORP | 44,111,916 | $200M | 2.9% | $4.55 | 0.0% | COM | 374163103 |
| MASI | MASIMO CORP | 1,462,400 | $195M | 2.8% | $166.52 | -30.3% | COM | 574795100 |
| ALKS | ALKERMES PLC | 6,654,033 | $186M | 2.7% | $26.93 | -1.0% | SHS | G01767105 |
| — | AKERO THERAPEUTICS INC | 5,919,435 | $170M | 2.5% | $24.38 | — | COM | 00973Y108 |
| APGE | APOGEE THERAPEUTICS INC | 2,712,096 | $159M | 2.3% | $27.01 | +77.4% | COM | 03770N101 |
| PEN | PENUMBRA INC | 795,750 | $155M | 2.2% | $249.29 | -24.2% | COM | 70975L107 |
| IMCR | IMMUNOCORE HLDGS PLC | 4,869,798 | $152M | 2.2% | $43.23 | — | ADS | 45258D105 |
| CYTK | CYTOKINETICS INC | 2,721,158 | $144M | 2.1% | $29.14 | +91.2% | COM NEW | 23282W605 |
| SYK | STRYKER CORPORATION | 396,921 | $143M | 2.1% | $340.46 | 0.0% | COM | 863667101 |
| RDNT | RADNET INC | 1,808,604 | $125M | 1.8% | $38.35 | +64.4% | COM | 750491102 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,645,703 | $114M | 1.7% | $28.18 | +54.3% | COM | G31249108 |
| IMTX | IMMATICS N.V | 10,000,000 | $114M | 1.7% | $11.40 | +3.9% | SHS | N44445109 |
| TARS | TARSUS PHARMACEUTICALS INC | 3,412,486 | $112M | 1.6% | $24.90 | +12.9% | COM | 87650L103 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,968,002 | $109M | 1.6% | $50.54 | +0.8% | COM | 90400D108 |
| SYRE | SPYRE THERAPEUTICS INC | 3,258,360 | $95.83M | 1.4% | $20.06 | +38.8% | COM NEW | 00773J202 |
| — | CARGO THERAPEUTICS INC | 4,098,955 | $75.63M | 1.1% | $22.58 | — | COM | 14179K101 |
| ARVN | ARVINAS INC | 2,782,329 | $68.53M | 1.0% | $23.38 | +11.7% | COM | 04335A105 |
| STOK | STOKE THERAPEUTICS INC | 4,652,285 | $57.18M | 0.8% | $23.21 | -39.0% | COM | 86150R107 |
| — | 89BIO INC | 7,378,548 | $54.6M | 0.8% | $11.28 | — | COM | 282559103 |
| CGON | CG ONCOLOGY INC | 1,344,074 | $50.71M | 0.7% | $36.56 | -4.1% | COM | 156944100 |
| GKOS | GLAUKOS CORP | 386,291 | $50.33M | 0.7% | $103.61 | +20.1% | COM | 377322102 |
| URGN | UROGEN PHARMA LTD | 3,787,347 | $48.1M | 0.7% | $15.20 | -2.4% | COM | M96088105 |
| NGNE | NEUROGENE INC | 1,135,256 | $47.64M | 0.7% | $34.20 | +13.4% | COM | 64135M105 |
| ORKA | ORUKA THERAPEUTICS INC | 1,850,648 | $45.36M | 0.7% | $34.79 | 0.0% | COM | 687604108 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 8,206,159 | $42.18M | 0.6% | $10.21 | -36.0% | COM | 68572M106 |
| — | SAGE THERAPEUTICS INC | 5,591,700 | $40.37M | 0.6% | $20.22 | — | COM | 78667J108 |
| TSHA | TAYSHA GENE THERAPIES INC | 14,946,420 | $30.04M | 0.4% | $1.90 | +15.6% | COM SHS | 877619106 |
| CGEM | CULLINAN THERAPEUTICS INC | 1,705,960 | $28.56M | 0.4% | $19.93 | -11.0% | COM | 230031106 |
| TEM | TEMPUS AI INC | 400,000 | $22.64M | 0.3% | $30.66 | +52.5% | CL A | 88023B103 |
| GHRS | GH RESEARCH PLC | 3,327,129 | $22.26M | 0.3% | $17.34 | -40.9% | ORDINARY SHARES | G3855L106 |
| LENZ | LENZ THERAPEUTICS INC | 863,389 | $20.5M | 0.3% | $20.79 | +6.8% | COM | 52635N103 |
| — | ESSA PHARMA INC | 3,261,496 | $19.76M | 0.3% | $6.44 | — | COM NEW | 29668H708 |
| — | TOURMALINE BIO INC | 741,656 | $19.07M | 0.3% | $24.66 | — | COM | 89157D105 |
| DNTH | DIANTHUS THERAPEUTICS INC | 666,667 | $18.25M | 0.3% | $21.73 | +28.2% | COM | 252828108 |
| ROIV | ROIVANT SCIENCES LTD | 1,454,273 | $16.78M | 0.2% | $8.28 | +37.5% | SHS | G76279101 |
| BIOA | BIOAGE LABS INC | 786,353 | $16.36M | 0.2% | $20.04 | 0.0% | COM | 09077V100 |
| REPL | REPLIMUNE GROUP INC | 1,133,787 | $12.43M | 0.2% | $6.97 | +45.7% | COM | 76029N106 |
| XNCR | XENCOR INC | 575,000 | $11.56M | 0.2% | $18.77 | 0.0% | COM | 98401F105 |
| TXG | 10X GENOMICS INC | 502,856 | $11.35M | 0.2% | $60.97 | -66.1% | CL A COM | 88025U109 |
| IMUX | IMMUNIC INC | 4,567,717 | $7.537M | 0.1% | $8.52 | -83.3% | COM | 4525EP101 |
| PCSC | PERCEPTIVE CAP SOLUTIONS COR | 742,500 | $7.432M | 0.1% | $10.07 | -0.1% | CL A ORD SHS | G70077105 |
| WVE | WAVE LIFE SCIENCES LTD | 900,000 | $7.38M | 0.1% | $5.98 | 0.0% | SHS | Y95308105 |
| IDYA | IDEAYA BIOSCIENCES INC | 200,000 | $6.336M | 0.1% | $37.92 | 0.0% | COM | 45166A102 |
| GPCR | STRUCTURE THERAPEUTICS INC | 125,000 | $5.486M | 0.1% | $39.27 | — | SPONSORED ADS | 86366E106 |
| MIST | MILESTONE PHARMACEUTICALS IN | 3,256,102 | $4.949M | 0.1% | $20.06 | -92.7% | COM | 59935V107 |
| — | ACELYRIN INC | 978,310 | $4.823M | 0.1% | $20.90 | — | COM | 00445A100 |
| XGN | EXAGEN INC | 1,511,866 | $4.672M | 0.1% | $11.83 | -78.1% | COM | 30068X103 |
| RGNX | REGENXBIO INC | 350,000 | $3.671M | 0.1% | $17.79 | -31.5% | COM | 75901B107 |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | 148,844 | $2.3M | 0.0% | $11.59 | 0.0% | COM | 04317A107 |
| — | ALLURION TECHNOLOGIES INC | 3,697,549 | $2.267M | 0.0% | $4.09 | — | COM SHS | 02008G102 |
| SABS | SAB BIOTHERAPEUTICS INC | 635,276 | $1.715M | 0.0% | $5.51 | -49.7% | COM NEW | 78397T202 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 50,000 | $800K | 0.0% | $15.99 | — | SPONSORED ADS | 152309100 |
| ADGM | ADAGIO MED HLDGS INC | 209,361 | $540K | 0.0% | $4.76 | 0.0% | COM | 00534B100 |
| QURE | UNIQURE NV | 10,000 | $49,300 | 0.0% | $6.51 | 0.0% | SHS | N90064101 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 350,000 | $22,575 | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |