Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q1 2025 (← Previous) (Next →)
Filing Date: May 15, 2025
Total Value: $6.538B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,993,687 | $660M | 10.1% | $231.65 | +41.8% | COM | 558868105 |
| ARGX | ARGENX SE | 673,497 | $399M | 6.1% | $351.97 | — | SPONSORED ADR | 04016X101 |
| PTCT | PTC THERAPEUTICS INC | 7,483,127 | $381M | 5.8% | $38.18 | +30.7% | COM | 69366J200 |
| NTRA | NATERA INC | 2,593,546 | $367M | 5.6% | $42.76 | +275.9% | COM | 632307104 |
| AXSM | AXSOME THERAPEUTICS INC | 2,922,729 | $341M | 5.2% | $56.00 | +103.5% | COM | 05464T104 |
| — | AKERO THERAPEUTICS INC | 7,419,340 | $300M | 4.6% | $26.03 | — | COM | 00973Y108 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 5,719,415 | $277M | 4.2% | $23.47 | +78.6% | COM | 74366E102 |
| RNAM | AVIDITY BIOSCIENCES INC | 8,746,926 | $258M | 3.9% | $24.66 | +26.3% | COM | 05370A108 |
| PEN | PENUMBRA INC | 862,770 | $231M | 3.5% | $247.59 | +9.3% | COM | 70975L107 |
| INSM | INSMED INC | 3,014,558 | $230M | 3.5% | $29.56 | +158.8% | COM PAR $.01 | 457669307 |
| ALKS | ALKERMES PLC | 6,884,698 | $227M | 3.5% | $27.15 | +20.1% | SHS | G01767105 |
| SYK | STRYKER CORPORATION | 590,221 | $220M | 3.4% | $348.93 | +8.1% | COM | 863667101 |
| — | VERONA PHARMA PLC | 2,848,800 | $181M | 2.8% | $52.59 | — | SPONSORED ADS | 925050106 |
| — | MERUS N V | 4,169,393 | $175M | 2.7% | $34.07 | — | COM | N5749R100 |
| TARS | TARSUS PHARMACEUTICALS INC | 3,316,032 | $170M | 2.6% | $25.49 | +93.9% | COM | 87650L103 |
| IMCR | IMMUNOCORE HLDGS PLC | 4,869,798 | $144M | 2.2% | $43.23 | — | ADS | 45258D105 |
| ACAD | ACADIA PHARMACEUTICALS INC | 8,540,117 | $142M | 2.2% | $21.38 | -15.1% | COM | 004225108 |
| RCKT | ROCKET PHARMACEUTICALS INC | 17,687,772 | $118M | 1.8% | $17.75 | -44.4% | COM | 77313F106 |
| RDNT | RADNET INC | 2,317,582 | $115M | 1.8% | $43.99 | +34.5% | COM | 750491102 |
| MASI | MASIMO CORP | 683,294 | $114M | 1.7% | $166.52 | +4.2% | COM | 574795100 |
| ZLAB | ZAI LAB LTD | 3,136,680 | $113M | 1.7% | $28.18 | — | ADR | 98887Q104 |
| CYTK | CYTOKINETICS INC | 2,721,158 | $109M | 1.7% | $29.14 | +57.7% | COM NEW | 23282W605 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,583,887 | $105M | 1.6% | $28.18 | +32.3% | COM | G31249108 |
| APGE | APOGEE THERAPEUTICS INC | 2,712,097 | $101M | 1.5% | $27.01 | +43.1% | COM | 03770N101 |
| ISRG | INTUITIVE SURGICAL INC | 202,456 | $100M | 1.5% | $553.02 | 0.0% | COM NEW | 46120E602 |
| GMED | GLOBUS MED INC | 1,125,000 | $82.35M | 1.3% | $79.38 | +4.1% | CL A | 379577208 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,707,402 | $61.83M | 0.9% | $50.54 | -17.7% | COM | 90400D108 |
| GHRS | GH RESEARCH PLC | 5,499,769 | $60.66M | 0.9% | $14.91 | -25.0% | ORDINARY SHARES | G3855L106 |
| SYRE | SPYRE THERAPEUTICS INC | 3,621,996 | $58.44M | 0.9% | $20.99 | -0.9% | COM NEW | 00773J202 |
| QURE | UNIQURE NV | 4,265,428 | $45.21M | 0.7% | $12.88 | +8.9% | SHS | N90064101 |
| URGN | UROGEN PHARMA LTD | 3,834,794 | $42.41M | 0.6% | $15.16 | -29.7% | COM | M96088105 |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 520,000 | $41.97M | 0.6% | $85.82 | 0.0% | COMMON STOCK | 36266G107 |
| CGON | CG ONCOLOGY INC | 1,701,216 | $41.66M | 0.6% | $36.07 | -22.0% | COM | 156944100 |
| BBNX | BETA BIONICS INC | 3,299,870 | $40.39M | 0.6% | $18.64 | 0.0% | COM | 08659B102 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 8,206,162 | $35.12M | 0.5% | $10.21 | -51.3% | COM | 68572M106 |
| STOK | STOKE THERAPEUTICS INC | 5,123,525 | $34.07M | 0.5% | $22.20 | -58.0% | COM | 86150R107 |
| IMTX | IMMATICS N.V | 6,909,510 | $31.16M | 0.5% | $11.07 | -52.9% | SHS | N44445109 |
| TSHA | TAYSHA GENE THERAPIES INC | 18,787,866 | $26.12M | 0.4% | $1.78 | -5.9% | COM SHS | 877619106 |
| VSTM | VERASTEM INC | 4,245,476 | $25.6M | 0.4% | $6.11 | 0.0% | COM NEW | 92337C203 |
| XNCR | XENCOR INC | 2,402,883 | $25.57M | 0.4% | $21.97 | -24.8% | COM | 98401F105 |
| ARVN | ARVINAS INC | 3,334,308 | $23.41M | 0.4% | $23.53 | -33.4% | COM | 04335A105 |
| LENZ | LENZ THERAPEUTICS INC | 863,389 | $22.2M | 0.3% | $20.79 | +18.5% | COM | 52635N103 |
| REPL | REPLIMUNE GROUP INC | 2,065,010 | $20.13M | 0.3% | $9.31 | +33.0% | COM | 76029N106 |
| ORKA | ORUKA THERAPEUTICS INC | 1,945,649 | $19.96M | 0.3% | $34.29 | -63.6% | COM | 687604108 |
| TEM | TEMPUS AI INC | 400,000 | $19.3M | 0.3% | $53.98 | 0.0% | CL A | 88023B103 |
| GKOS | GLAUKOS CORP | 190,000 | $18.7M | 0.3% | $133.38 | 0.0% | COM | 377322102 |
| DYN | DYNE THERAPEUTICS INC | 1,690,567 | $17.68M | 0.3% | $26.82 | -46.7% | COM | 26818M108 |
| — | CARGO THERAPEUTICS INC | 4,124,859 | $16.79M | 0.3% | $22.58 | — | COM | 14179K101 |
| DGX | QUEST DIAGNOSTICS INC | 98,997 | $16.75M | 0.3% | $161.93 | 0.0% | COM | 74834L100 |
| CMPS | COMPASS PATHWAYS PLC | 5,538,168 | $15.84M | 0.2% | $3.37 | — | SPONSORED ADS | 20451W101 |
| NGNE | NEUROGENE INC | 1,348,656 | $15.79M | 0.2% | $34.68 | -49.9% | COM | 64135M105 |
| — | RAPT THERAPEUTICS INC | 11,764,000 | $14.35M | 0.2% | $1.58 | — | COM | 75382E109 |
| — | 89BIO INC | 1,967,527 | $14.3M | 0.2% | $11.24 | — | COM | 282559103 |
| CGEM | CULLINAN THERAPEUTICS INC | 1,705,960 | $12.91M | 0.2% | $19.93 | -51.9% | COM | 230031106 |
| BEAM | BEAM THERAPEUTICS INC | 438,659 | $8.567M | 0.1% | $26.20 | 0.0% | COM | 07373V105 |
| CRVS | CORVUS PHARMACEUTICALS INC | 2,679,479 | $8.521M | 0.1% | $7.47 | -36.9% | COM | 221015100 |
| PCSC | PERCEPTIVE CAP SOLUTIONS COR | 742,500 | $7.648M | 0.1% | $10.07 | +1.8% | CL A ORD SHS | G70077105 |
| WVE | WAVE LIFE SCIENCES LTD | 900,000 | $7.272M | 0.1% | $5.98 | +83.0% | SHS | Y95308105 |
| XGN | EXAGEN INC | 1,511,866 | $5.428M | 0.1% | $11.83 | -68.1% | COM | 30068X103 |
| KMTS | KESTRA MED TECHNOLOGIES LTD | 200,000 | $4.984M | 0.1% | $22.98 | 0.0% | SHS | G52441105 |
| ALUR | ALLURION TECHNOLOGIES INC | 1,050,063 | $3.371M | 0.1% | $4.30 | 0.0% | COMMON STOCK | 02008G201 |
| BIOA | BIOAGE LABS INC | 786,353 | $2.957M | 0.0% | $20.04 | -76.9% | COM | 09077V100 |
| CBLL | CERIBELL INC | 150,000 | $2.881M | 0.0% | $27.25 | -18.4% | COM | 15678C102 |
| TENX | TENAX THERAPEUTICS INC | 378,346 | $2.478M | 0.0% | $6.41 | 0.0% | COM NEW | 88032L605 |
| MIST | MILESTONE PHARMACEUTICALS IN | 2,506,102 | $2.005M | 0.0% | $20.06 | -90.1% | COM | 59935V107 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 50,000 | $719K | 0.0% | $15.99 | — | SPONSORED ADS | 152309100 |
| ADGM | ADAGIO MED HLDGS INC | 209,361 | $169K | 0.0% | $4.76 | -77.7% | COM | 00534B100 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 350,000 | $16,450 | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |