Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q2 2025 (← Previous) (Next →)
Filing Date: Aug 14, 2025
Total Value: $7.021B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,993,687 | $603M | 8.6% | $231.65 | +28.6% | COM | 558868105 |
| NTRA | NATERA INC | 2,593,645 | $438M | 6.2% | $42.76 | +264.4% | COM | 632307104 |
| PTCT | PTC THERAPEUTICS INC | 7,746,415 | $378M | 5.4% | $38.50 | +23.3% | COM | 69366J200 |
| ARGX | ARGENX SE | 673,497 | $371M | 5.3% | $351.97 | — | SPONSORED ADR | 04016X101 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 5,756,277 | $318M | 4.5% | $23.47 | +104.5% | COM | 74366E102 |
| INSM | INSMED INC | 3,084,558 | $310M | 4.4% | $30.62 | +149.7% | COM PAR $.01 | 457669307 |
| — | AKERO THERAPEUTICS INC | 5,477,561 | $292M | 4.2% | $26.03 | — | COM | 00973Y108 |
| — | VERONA PHARMA PLC | 3,051,878 | $289M | 4.1% | $55.39 | — | SPONSORED ADS | 925050106 |
| RNAM | AVIDITY BIOSCIENCES INC | 9,618,845 | $273M | 3.9% | $25.13 | +18.6% | COM | 05370A108 |
| SYK | STRYKER CORPORATION | 590,517 | $234M | 3.3% | $348.93 | +6.5% | COM | 863667101 |
| PEN | PENUMBRA INC | 863,553 | $222M | 3.2% | $247.59 | +9.9% | COM | 70975L107 |
| — | MERUS N V | 4,000,553 | $210M | 3.0% | $34.07 | — | COM | N5749R100 |
| ACAD | ACADIA PHARMACEUTICALS INC | 8,995,547 | $194M | 2.8% | $21.24 | -12.5% | COM | 004225108 |
| ZLAB | ZAI LAB LTD | 5,536,876 | $194M | 2.8% | $31.12 | — | ADR | 98887Q104 |
| AXSM | AXSOME THERAPEUTICS INC | 1,516,903 | $158M | 2.3% | $56.00 | +89.1% | COM | 05464T104 |
| RDNT | RADNET INC | 2,690,344 | $153M | 2.2% | $45.50 | +20.7% | COM | 750491102 |
| IMCR | IMMUNOCORE HLDGS PLC | 4,869,798 | $153M | 2.2% | $43.23 | — | ADS | 45258D105 |
| ALKS | ALKERMES PLC | 4,682,289 | $134M | 1.9% | $27.15 | +9.6% | SHS | G01767105 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,062,072 | $133M | 1.9% | $114.68 | 0.0% | COM | 64125C109 |
| TARS | TARSUS PHARMACEUTICALS INC | 3,111,680 | $126M | 1.8% | $25.49 | +76.6% | COM | 87650L103 |
| APGE | APOGEE THERAPEUTICS INC | 2,712,097 | $118M | 1.7% | $27.01 | +40.8% | COM | 03770N101 |
| MASI | MASIMO CORP | 683,294 | $115M | 1.6% | $166.52 | -4.1% | COM | 574795100 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,584,131 | $110M | 1.6% | $28.18 | +23.7% | COM | G31249108 |
| ISRG | INTUITIVE SURGICAL INC | 202,456 | $110M | 1.6% | $553.02 | -5.5% | COM NEW | 46120E602 |
| CYTK | CYTOKINETICS INC | 2,721,158 | $89.91M | 1.3% | $29.14 | +19.3% | COM NEW | 23282W605 |
| DGX | QUEST DIAGNOSTICS INC | 500,000 | $89.81M | 1.3% | $170.08 | +1.2% | COM | 74834L100 |
| QURE | UNIQURE NV | 5,158,231 | $71.91M | 1.0% | $12.98 | +3.7% | SHS | N90064101 |
| GHRS | GH RESEARCH PLC | 5,540,457 | $67.54M | 1.0% | $14.91 | -26.4% | ORDINARY SHARES | G3855L106 |
| URGN | UROGEN PHARMA LTD | 4,543,895 | $62.25M | 0.9% | $14.29 | -32.9% | COM | M96088105 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,707,402 | $62.08M | 0.9% | $50.54 | -28.7% | COM | 90400D108 |
| ABT | ABBOTT LABS | 444,000 | $60.39M | 0.9% | $130.60 | 0.0% | COM | 002824100 |
| STOK | STOKE THERAPEUTICS INC | 5,123,525 | $58.15M | 0.8% | $22.20 | -57.2% | COM | 86150R107 |
| TSHA | TAYSHA GENE THERAPIES INC | 25,021,584 | $57.8M | 0.8% | $1.88 | +15.8% | COM SHS | 877619106 |
| SYRE | SPYRE THERAPEUTICS INC | 3,621,996 | $54.22M | 0.8% | $20.99 | -29.5% | COM NEW | 00773J202 |
| BBNX | BETA BIONICS INC | 3,299,191 | $48.04M | 0.7% | $18.64 | -24.1% | COM | 08659B102 |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 626,000 | $46.37M | 0.7% | $83.06 | -16.3% | COMMON STOCK | 36266G107 |
| GH | GUARDANT HEALTH INC | 856,501 | $44.57M | 0.6% | $44.66 | 0.0% | COM | 40131M109 |
| CGON | CG ONCOLOGY INC | 1,701,216 | $44.23M | 0.6% | $36.07 | -33.2% | COM | 156944100 |
| RCKT | ROCKET PHARMACEUTICALS INC | 17,687,772 | $43.34M | 0.6% | $17.75 | -71.5% | COM | 77313F106 |
| IMTX | IMMATICS N.V | 6,970,152 | $37.5M | 0.5% | $11.07 | -55.2% | SHS | N44445109 |
| SLNO | SOLENO THERAPEUTICS INC | 424,408 | $35.56M | 0.5% | $74.85 | 0.0% | COM | 834203309 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 741,090 | $34.98M | 0.5% | $40.73 | 0.0% | CLASS A ORD | 61559X104 |
| TEM | TEMPUS AI INC | 400,000 | $25.42M | 0.4% | $53.98 | +6.2% | CL A | 88023B103 |
| LENZ | LENZ THERAPEUTICS INC | 863,389 | $25.31M | 0.4% | $20.79 | +30.9% | COM | 52635N103 |
| CMPS | COMPASS PATHWAYS PLC | 8,221,929 | $23.02M | 0.3% | $3.19 | — | SPONSORED ADS | 20451W101 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 8,306,062 | $22.26M | 0.3% | $10.12 | -71.2% | COM | 68572M106 |
| ORKA | ORUKA THERAPEUTICS INC | 1,945,649 | $21.81M | 0.3% | $34.29 | -69.6% | COM | 687604108 |
| NGNE | NEUROGENE INC | 1,362,456 | $20.37M | 0.3% | $34.49 | -54.5% | COM | 64135M105 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 1,529,836 | $20.1M | 0.3% | $13.23 | — | SPONSORED ADS | 152309100 |
| — | 89BIO INC | 1,967,527 | $19.32M | 0.3% | $11.24 | — | COM | 282559103 |
| REPL | REPLIMUNE GROUP INC | 2,065,010 | $19.18M | 0.3% | $9.31 | -6.2% | COM | 76029N106 |
| XNCR | XENCOR INC | 2,402,883 | $18.89M | 0.3% | $21.97 | -59.2% | COM | 98401F105 |
| VSTM | VERASTEM INC | 4,251,616 | $17.64M | 0.3% | $6.11 | +2.5% | COM NEW | 92337C203 |
| DYN | DYNE THERAPEUTICS INC | 1,690,567 | $16.09M | 0.2% | $26.82 | -58.9% | COM | 26818M108 |
| JBIO | JADE BIOSCIENCES INC | 1,449,273 | $14.48M | 0.2% | $33.31 | 0.0% | COM NEW | 008064206 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 467,000 | $13.43M | 0.2% | $30.88 | 0.0% | COM | 22663K107 |
| CGEM | CULLINAN THERAPEUTICS INC | 1,705,960 | $12.85M | 0.2% | $19.93 | -59.7% | COM | 230031106 |
| XGN | EXAGEN INC | 1,696,866 | $11.84M | 0.2% | $11.21 | -45.8% | COM | 30068X103 |
| RAPT | RAPT THERAPEUTICS INC | 1,470,499 | $11.76M | 0.2% | $7.63 | 0.0% | COM NEW | 75382E208 |
| CRVS | CORVUS PHARMACEUTICALS INC | 2,679,479 | $10.72M | 0.2% | $7.47 | -51.3% | COM | 221015100 |
| PCSC | PERCEPTIVE CAP SOLUTIONS COR | 742,500 | $7.885M | 0.1% | $10.07 | +3.8% | CL A ORD SHS | G70077105 |
| CTMX | CYTOMX THERAPEUTICS INC | 3,461,500 | $7.858M | 0.1% | $1.61 | 0.0% | COM | 23284F105 |
| ALUR | ALLURION TECHNOLOGIES INC | 2,542,603 | $6.179M | 0.1% | $3.30 | -21.4% | COMMON STOCK | 02008G201 |
| WVE | WAVE LIFE SCIENCES LTD | 900,000 | $5.85M | 0.1% | $5.98 | +10.5% | SHS | Y95308105 |
| — | CARGO THERAPEUTICS INC | 1,212,562 | $4.996M | 0.1% | $22.58 | — | COM | 14179K101 |
| MIST | MILESTONE PHARMACEUTICALS IN | 2,506,102 | $4.862M | 0.1% | $20.06 | -93.4% | COM | 59935V107 |
| OMDA | OMADA HEALTH INC | 200,000 | $3.66M | 0.1% | $17.31 | 0.0% | COM | 68170A108 |
| KMTS | KESTRA MED TECHNOLOGIES LTD | 200,000 | $3.316M | 0.0% | $22.98 | -5.0% | SHS | G52441105 |
| CBLL | CERIBELL INC | 150,000 | $2.809M | 0.0% | $27.25 | -37.6% | COM | 15678C102 |
| TENX | TENAX THERAPEUTICS INC | 378,346 | $2.179M | 0.0% | $6.41 | -9.9% | COM NEW | 88032L605 |
| IMUX | IMMUNIC INC | 402,107 | $280K | 0.0% | $0.92 | 0.0% | COM | 4525EP101 |
| ADGM | ADAGIO MED HLDGS INC | 209,361 | $272K | 0.0% | $4.76 | -76.1% | COM | 00534B100 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 350,000 | $10,080 | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |