Frazier Life Sciences Management, L.P. Diversified Active

CIK: 0001892134 · Show all filings

Period: Q4 2023 (← Previous) (Next →)

Filing Date: Feb 14, 2024

Total Value ($000): $1,870,349 (100.0% shares, 0.0% debt)

Holdings (49)

MIRM MIRUM PHARMACEUTICALS INC 10.3%
Value ($000) $191,744 Shares 6,495,392 Est. Cost $23.31 Unrealized +29.9%
— HILLEVAX INC 8.4%
Value ($000) $156,993 Shares 9,781,472 Est. Cost $11.23 Unrealized —
NAMS NEWAMSTERDAM PHARMA COMPANY 7.2%
Value ($000) $135,511 Shares 12,131,705 Est. Cost $10.46 Unrealized -12.4%
KRYS KRYSTAL BIOTECH INC 6.6%
Value ($000) $122,628 Shares 988,460 Est. Cost $64.17 Unrealized +72.8%
BBIO BRIDGEBIO PHARMA INC 5.9%
Value ($000) $110,047 Shares 2,725,949 Est. Cost $17.20 Unrealized +74.7%
RYTM RHYTHM PHARMACEUTICALS INC 5.8%
Value ($000) $109,009 Shares 2,371,304 Est. Cost $19.67 Unrealized +60.4%
PHAT PHATHOM PHARMACEUTICALS INC 4.9%
Value ($000) $92,298 Shares 10,109,279 Est. Cost $13.68 Unrealized -37.0%
PCVX VAXCYTE INC 3.9%
Value ($000) $73,125 Shares 1,164,405 Est. Cost $21.85 Unrealized +137.7%
— VERONA PHARMA PLC 3.2%
Value ($000) $59,925 Shares 3,014,349 Est. Cost $14.56 Unrealized —
— ALPINE IMMUNE SCIENCES INC 3.2%
Value ($000) $59,677 Shares 3,131,008 Est. Cost $9.44 Unrealized —
APLS APELLIS PHARMACEUTICALS INC 2.8%
Value ($000) $52,986 Shares 885,165 Est. Cost $46.01 Unrealized +10.3%
RCKT ROCKET PHARMACEUTICALS INC 2.4%
Value ($000) $45,645 Shares 1,523,013 Est. Cost $18.48 Unrealized +19.4%
IRON DISC MEDICINE INC 2.4%
Value ($000) $45,342 Shares 785,000 Est. Cost $38.09 Unrealized +34.4%
KALV KALVISTA PHARMACEUTICALS INC 2.4%
Value ($000) $44,373 Shares 3,622,294 Est. Cost $9.66 Unrealized -5.9%
TARS TARSUS PHARMACEUTICALS INC 1.9%
Value ($000) $36,197 Shares 1,787,527 Est. Cost $17.82 Unrealized -6.3%
EWTX EDGEWISE THERAPEUTICS INC 1.6%
Value ($000) $29,179 Shares 2,667,203 Est. Cost $7.62 Unrealized -7.9%
RVMD REVOLUTION MEDICINES INC 1.5%
Value ($000) $28,607 Shares 997,455 Est. Cost $25.35 Unrealized -5.2%
ANTX AN2 THERAPEUTICS INC 1.5%
Value ($000) $28,458 Shares 1,388,889 Est. Cost $11.32 Unrealized +47.7%
ARQT ARCUTIS BIOTHERAPEUTICS INC 1.5%
Value ($000) $28,308 Shares 8,764,232 Est. Cost $17.08 Unrealized -84.1%
— AEROVATE THERAPEUTICS INC 1.5%
Value ($000) $27,266 Shares 1,204,867 Est. Cost $17.37 Unrealized —
AUTL AUTOLUS THERAPEUTICS PLC 1.3%
Value ($000) $24,130 Shares 3,746,857 Est. Cost $4.17 Unrealized —
MGNX MACROGENICS INC 1.2%
Value ($000) $23,104 Shares 2,401,704 Est. Cost $6.25 Unrealized +10.6%
ACAD ACADIA PHARMACEUTICALS INC 1.2%
Value ($000) $22,885 Shares 730,917 Est. Cost $17.25 Unrealized +38.5%
— 89BIO INC 1.2%
Value ($000) $22,340 Shares 2,000,000 Est. Cost $11.17 Unrealized —
— MERUS N V 1.1%
Value ($000) $20,528 Shares 746,479 Est. Cost $25.59 Unrealized —
ORIC ORIC PHARMACEUTICALS INC 1.1%
Value ($000) $19,714 Shares 2,142,855 Est. Cost $5.68 Unrealized +27.3%
ANAB ANAPTYSBIO INC 1.0%
Value ($000) $19,272 Shares 899,700 Est. Cost $30.26 Unrealized -43.0%
SVRA SAVARA INC 1.0%
Value ($000) $18,800 Shares 4,000,000 Est. Cost $3.56 Unrealized +7.5%
SLNO SOLENO THERAPEUTICS INC 1.0%
Value ($000) $18,714 Shares 464,937 Est. Cost $6.05 Unrealized +370.0%
— CEREVEL THERAPEUTICS HLDNG I 0.9%
Value ($000) $16,663 Shares 393,000 Est. Cost $28.54 Unrealized —
— DECIPHERA PHARMACEUTICALS IN 0.9%
Value ($000) $16,482 Shares 1,021,800 Est. Cost $15.39 Unrealized —
MDGL MADRIGAL PHARMACEUTICALS INC 0.9%
Value ($000) $16,059 Shares 69,406 Est. Cost $174.99 Unrealized 0.0%
DYN DYNE THERAPEUTICS INC 0.8%
Value ($000) $15,758 Shares 1,184,840 Est. Cost $9.77 Unrealized 0.0%
SLN SILENCE THERAPEUTICS PLC 0.8%
Value ($000) $15,306 Shares 881,173 Est. Cost $19.00 Unrealized —
TYRA TYRA BIOSCIENCES INC 0.8%
Value ($000) $14,216 Shares 1,026,420 Est. Cost $11.75 Unrealized +10.2%
CRNX CRINETICS PHARMACEUTICALS IN 0.8%
Value ($000) $14,142 Shares 397,483 Est. Cost $20.28 Unrealized +51.2%
GPCR STRUCTURE THERAPEUTICS INC 0.7%
Value ($000) $12,929 Shares 317,190 Est. Cost $40.76 Unrealized —
ARVN ARVINAS INC 0.6%
Value ($000) $11,744 Shares 285,331 Est. Cost $67.21 Unrealized -65.2%
COGT COGENT BIOSCIENCES INC 0.6%
Value ($000) $11,732 Shares 1,995,267 Est. Cost $7.30 Unrealized +4.9%
AGIO AGIOS PHARMACEUTICALS INC 0.6%
Value ($000) $11,651 Shares 523,166 Est. Cost $24.67 Unrealized -9.1%
APGE APOGEE THERAPEUTICS INC 0.6%
Value ($000) $11,176 Shares 400,000 Est. Cost $22.03 Unrealized -9.0%
TRVI TREVI THERAPEUTICS INC 0.5%
Value ($000) $9,891 Shares 7,381,090 Est. Cost $2.78 Unrealized -45.6%
— THESEUS PHARMACEUTICALS INC 0.5%
Value ($000) $8,578 Shares 2,118,051 Est. Cost $6.45 Unrealized —
NTLA INTELLIA THERAPEUTICS INC 0.3%
Value ($000) $6,210 Shares 203,684 Est. Cost $84.72 Unrealized -66.1%
— MIRATI THERAPEUTICS INC 0.3%
Value ($000) $4,700 Shares 80,000 Est. Cost $58.75 Unrealized —
— BLUEBIRD BIO INC 0.1%
Value ($000) $2,360 Shares 1,709,907 Est. Cost $5.85 Unrealized —
— GRITSTONE BIO INC 0.1%
Value ($000) $2,103 Shares 1,030,878 Est. Cost $4.12 Unrealized —
NAMSW NEWAMSTERDAM PHARMA COMPANY 0.1%
Value ($000) $1,566 Shares 500,333 Est. Cost $0.87 Unrealized —
ACRS ACLARIS THERAPEUTICS INC 0.0%
Value ($000) $278 Shares 264,377 Est. Cost $13.64 Unrealized -77.6%