TYRA BIOSCIENCES INC

Ticker: TYRA CUSIP: 90240B106 Class: Common Stock

Note: Option positions (PUT/CALL) are excluded.

New Positions (23)

Increased Positions (42)

5AM Venture Management, LLC
Value ($000) $27,060 (+105.9%) Shares 1,029,298 (+9.6%)
Caligan Partners LP
Value ($000) $24,825 (+154.6%) Shares 944,257 (+35.5%)
Sio Capital Management, LLC
Value ($000) $13,829 (+92.0%) Shares 526,002 (+2.1%)
FARALLON CAPITAL MANAGEMENT LLC
Value ($000) $54,337 (+239.6%) Shares 2,066,818 (+80.7%)
Point72 Asset Management, L.P.
Value ($000) $22,983 (+482.5%) Shares 874,192 (+210.0%)
Eversept Partners, LP
Value ($000) $7,323 (+92.0%) Shares 278,564 (+2.1%)
BOOTHBAY FUND MANAGEMENT, LLC
Value ($000) $5,815 (+122.7%) Shares 221,177 (+18.5%)
MARSHALL WACE, LLP
Value ($000) $18,716 (+122.2%) Shares 711,891 (+18.3%)
STATE STREET CORP
Value ($000) $19,703 (+228.7%) Shares 749,463 (+74.9%)
BlackRock, Inc.
Value ($000) $54,852 (+109.7%) Shares 2,086,423 (+11.6%)
Invesco Ltd.
Value ($000) $3,403 (+1468.2%) Shares 129,435 (+734.5%)
JANUS HENDERSON GROUP PLC
Value ($000) $77,085 (+91.6%) Shares 2,935,442 (+2.1%)
ALPS ADVISORS INC
Value ($000) $1,152 (+233.4%) Shares 43,827 (+77.4%)
GOLDMAN SACHS GROUP INC
Value ($000) $4,795 (+242.2%) Shares 182,387 (+82.1%)
Squarepoint Ops LLC
Value ($000) $1,431 (+737.3%) Shares 54,424 (+345.6%)
DIMENSIONAL FUND ADVISORS LP
Value ($000) $2,514 (+353.0%) Shares 95,640 (+141.0%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $17,296 (+106.9%) Shares 657,756 (+10.1%)
BARCLAYS PLC
Value ($000) $2,006 (+126.8%) Shares 76,309 (+102.8%)
RAYMOND JAMES FINANCIAL INC
Value ($000) $4,470 (+152.8%) Shares 170,032 (+34.5%)
VANGUARD GROUP INC
Value ($000) $41,349 (+94.4%) Shares 1,572,785 (+3.5%)

Decreased Positions (36)

Canaan Partners XI LLC
Value ($000) $88,711 (+75.7%) Shares 3,374,329 (-6.5%)
Alta Partners Management Company, L.P.
Value ($000) $100,518 (+76.1%) Shares 3,823,425 (-6.3%)
Kynam Capital Management, LP
Value ($000) $41,130 (+26.2%) Shares 1,564,492 (-32.9%)
BVF INC/IL
Value ($000) $55,936 (+9.5%) Shares 2,127,665 (-41.7%)
HighVista Strategies LLC
Value ($000) $922 (+0.2%) Shares 35,086 (-46.7%)
AlphaQuest LLC
Value ($000) $56 (-86.6%) Shares 2,139 (-92.9%)
JACOBS LEVY EQUITY MANAGEMENT, INC
Value ($000) $3,411 (-3.1%) Shares 129,753 (-48.4%)
TWO SIGMA INVESTMENTS, LP
Value ($000) $2,814 (+0.8%) Shares 107,023 (-46.3%)
TWO SIGMA ADVISERS, LP
Value ($000) $1,548 (-2.2%) Shares 58,900 (-48.0%)
MORGAN STANLEY
Value ($000) $3,126 (-30.6%) Shares 118,898 (-63.1%)
BANK OF AMERICA CORP /DE/
Value ($000) $1,007 (-46.4%) Shares 38,310 (-71.5%)
BALYASNY ASSET MANAGEMENT L.P.
Value ($000) $21,514 (+81.6%) Shares 818,326 (-3.3%)
Nuveen, LLC
Value ($000) $1,245 (+10.6%) Shares 47,349 (-41.1%)
AMERIPRISE FINANCIAL INC
Value ($000) $1,436 (+17.8%) Shares 54,625 (-37.3%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $3,007 (+49.3%) Shares 114,388 (-20.6%)
XTX Topco Ltd
Value ($000) $800 (+69.6%) Shares 30,414 (-9.8%)
BNP PARIBAS ARBITRAGE, SA
Value ($000) $3,162 (+75.4%) Shares 120,278 (-6.7%)
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO
Value ($000) $487 (+39.6%) Shares 18,542 (-25.7%)
NORTHERN TRUST CORP
Value ($000) $5,283 (+81.1%) Shares 200,956 (-3.6%)
PDT Partners, LLC
Value ($000) $1,112 (+83.5%) Shares 42,284 (-2.4%)