Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q2 2023 (← Previous) (Next →)
Filing Date: Aug 14, 2023
Total Value: $17.28B (99.2% shares, 0.8% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | Seagen Inc. | 44,554,162 | $8.575B | 49.6% | $195.69 | — | COM | 81181C104 |
| INCY | Incyte Corporation | 36,178,056 | $2.252B | 13.0% | $72.80 | -8.2% | COM | 45337C102 |
| ONC | BeiGene, Ltd. | 11,668,897 | $2.081B | 12.0% | $136.93 | — | SPONSORED ADR | 07725L102 |
| ACAD | ACADIA Pharmaceuticals Inc. | 42,864,612 | $1.027B | 5.9% | $18.93 | +17.4% | COM | 004225108 |
| MDGL | Madrigal Pharmaceuticals, Inc. | 1,545,113 | $357M | 2.1% | $104.60 | +158.9% | COM | 558868105 |
| BMRN | BioMarin Pharmaceutical Inc. | 3,810,248 | $330M | 1.9% | $81.02 | +16.1% | COM | 09061G101 |
| IMCR | Immunocore Holdings plc | 2,520,731 | $151M | 0.9% | $42.57 | — | ADS | 45258D105 |
| — | Invitae Corporation | 300,000,000 | $135M | 0.8% | $0.45 | — | Note 1.5% 4/1/2028 | 46185LAD5 |
| KOD | Kodiak Sciences Inc. | 17,310,490 | $119M | 0.7% | $30.30 | -79.8% | COM | 50015M109 |
| — | Akero Therapeutics, Inc. | 2,368,378 | $111M | 0.6% | $33.89 | — | COM | 00973Y108 |
| ARGX | argenx SE | 280,159 | $109M | 0.6% | $79.01 | — | SPONSORED ADR | 04016X101 |
| RYTM | Rhythm Pharmaceuticals, Inc. | 6,498,267 | $107M | 0.6% | $23.52 | -23.3% | COM | 76243J105 |
| REPL | Replimune Group, Inc. | 4,578,280 | $106M | 0.6% | $19.30 | +1.2% | COM | 76029N106 |
| ABCL | AbCellera Biologics Inc. | 16,450,180 | $106M | 0.6% | $31.54 | -78.4% | COM | 00288U106 |
| KYMR | Kymera Therapeutics, Inc. | 4,375,340 | $101M | 0.6% | $31.74 | -9.7% | COM | 501575104 |
| ROIV | Roivant Sciences Ltd. | 9,428,592 | $95.04M | 0.6% | $8.38 | +6.7% | SHS | G76279101 |
| BCRX | BioCryst Pharmaceuticals, Inc. | 12,710,818 | $89.48M | 0.5% | $6.35 | +26.3% | COM | 09058V103 |
| — | SpringWorks Therapeutics, Inc. | 2,999,846 | $78.66M | 0.5% | $25.92 | — | COM | 85205L107 |
| TRDA | Entrada Therapeutics, Inc. | 4,865,819 | $73.67M | 0.4% | $16.96 | — | COM | 29384C108 |
| RVMD | Revolution Medicines, Inc. | 2,691,493 | $72M | 0.4% | $26.29 | -6.7% | COM | 76155X100 |
| IMTX | Immatics N.V. | 5,640,816 | $65.1M | 0.4% | $10.84 | -13.9% | SHS | N44445109 |
| — | Chinook Therapeutics, Inc. | 1,455,202 | $55.91M | 0.3% | $14.83 | — | COM | 16961L106 |
| — | Mirati Therapeutics, Inc. | 1,409,784 | $50.94M | 0.3% | $22.85 | — | COM | 60468T105 |
| — | DICE Therapeutics, Inc. | 1,035,786 | $48.12M | 0.3% | $31.65 | — | COM | 23345J104 |
| BMEA | Biomea Fusion, Inc. | 2,108,949 | $46.29M | 0.3% | $8.56 | +265.5% | COM | 09077A106 |
| PRLD | Prelude Therapeutics Inc. | 10,123,824 | $45.56M | 0.3% | $28.24 | -78.8% | COM | 74065P101 |
| DNLI | Denali Therapeutics Inc. | 1,455,322 | $42.95M | 0.2% | $27.58 | +2.0% | COM | 24823R105 |
| — | Kiniksa Pharmaceuticals, Ltd. | 2,809,577 | $39.56M | 0.2% | $17.35 | — | COM CL A | G5269C101 |
| CERS | Cerus Corporation | 16,067,558 | $39.53M | 0.2% | $4.69 | -49.4% | COM | 157085101 |
| NRIX | Nurix Therapeutics, Inc. | 3,882,125 | $38.78M | 0.2% | $22.27 | -54.2% | COM | 67080M103 |
| RARE | Ultragenyx Pharmaceutical Inc. | 783,059 | $36.12M | 0.2% | $87.90 | -47.2% | COM | 90400D108 |
| — | Aerovate Therapeutics, Inc. | 1,963,479 | $33.67M | 0.2% | $21.15 | — | COM | 008064107 |
| — | IGM Biosciences, Inc. | 3,157,210 | $29.14M | 0.2% | $17.75 | — | COM | 449585108 |
| XENE | Xenon Pharmaceuticals Inc. | 751,639 | $28.94M | 0.2% | $13.09 | +203.7% | COM | 98420N105 |
| — | ImmunoGen, Inc. | 1,520,097 | $28.68M | 0.2% | $18.87 | — | COM | 45253H101 |
| — | DBV Technologies S.A. | 14,614,264 | $27.77M | 0.2% | $19.06 | — | SPONSORED ADR | 23306J101 |
| — | Verve Therapeutics, Inc. | 1,416,530 | $26.56M | 0.2% | $60.25 | — | COM | 92539P101 |
| — | 2seventy bio, Inc. | 2,497,526 | $25.27M | 0.1% | $18.72 | — | COMMON STOCK | 901384107 |
| IDYA | IDEAYA Biosciences, Inc. | 1,062,123 | $24.96M | 0.1% | $14.62 | +40.6% | COM | 45166A102 |
| STOK | Stoke Therapeutics, Inc. | 2,130,238 | $22.64M | 0.1% | $10.71 | -0.7% | COM | 86150R107 |
| BCYC | Bicycle Therapeutics plc | 843,814 | $21.53M | 0.1% | $23.26 | — | SPONSORED ADS | 088786108 |
| GLUE | Monte Rosa Therapeutics, Inc. | 3,023,951 | $20.71M | 0.1% | $6.53 | -0.9% | COM | 61225M102 |
| CABA | Cabaletta Bio, Inc. | 1,594,000 | $20.58M | 0.1% | $8.14 | +33.4% | COM | 12674W109 |
| KRYS | Krystal Biotech, Inc. | 169,934 | $19.95M | 0.1% | $34.45 | +196.4% | COM | 501147102 |
| SMMT | Summit Therapeutics Inc. | 6,304,705 | $15.82M | 0.1% | $2.44 | -25.2% | COM | 86627T108 |
| ANAB | AnaptysBio, Inc. | 775,924 | $15.78M | 0.1% | $27.04 | -25.0% | COM | 032724106 |
| PRME | Prime Medicine, Inc. | 1,028,466 | $15.07M | 0.1% | $18.06 | -22.7% | COM | 74168J101 |
| PACB | Pacific Biosciences of California, Inc. | 1,127,782 | $15M | 0.1% | $15.59 | -22.0% | COM | 69404D108 |
| RLAY | Relay Therapeutics, Inc. | 1,160,117 | $14.57M | 0.1% | $13.78 | -9.8% | COM | 75943R102 |
| SPRY | ARS Pharmaceuticals, Inc. | 2,006,451 | $13.44M | 0.1% | $6.49 | +2.3% | COM | 82835W108 |
| DAWN | Day One Biopharmaceuticals, Inc. | 1,000,000 | $11.94M | 0.1% | $13.06 | 0.0% | COM | 23954D109 |
| SANA | Sana Biotechnology, Inc. | 2,000,000 | $11.92M | 0.1% | $4.00 | +44.2% | COM | 799566104 |
| COGT | Cogent Biosciences, Inc. | 979,600 | $11.6M | 0.1% | $11.47 | 0.0% | COM | 19240Q201 |
| — | POINT Biopharma Global Inc. | 1,169,103 | $10.59M | 0.1% | $7.73 | — | COM | 730541109 |
| ADAPY | Adaptimmune Therapeutics plc | 10,969,282 | $10.15M | 0.1% | $5.27 | — | SPONSORED ADR | 00653A107 |
| — | Invitae Corporation | 8,881,104 | $10.04M | 0.1% | $24.10 | — | COM | 46185L103 |
| VSTM | Verastem, Inc. | 1,336,485 | $9.943M | 0.1% | $6.94 | 0.0% | COM | 92337C203 |
| GERN | Geron Corporation | 3,061,224 | $9.827M | 0.1% | $2.84 | +0.2% | COM | 374163103 |
| HRTX | Heron Therapeutics, Inc. | 8,131,678 | $9.433M | 0.1% | $17.29 | -89.7% | COM | 427746102 |
| — | Athira Pharma, Inc. | 3,153,807 | $9.304M | 0.1% | $6.91 | — | COM | 04746L104 |
| RNAM | Avidity Biosciences, Inc. | 799,451 | $8.866M | 0.1% | $18.93 | -33.7% | COM | 05370A108 |
| — | bluebird bio, Inc. | 2,499,715 | $8.224M | 0.0% | $22.65 | — | COM | 09609G100 |
| FATE | Fate Therapeutics, Inc. | 1,671,717 | $7.957M | 0.0% | $8.98 | -38.6% | COM | 31189P102 |
| ALLO | Allogene Therapeutics, Inc. | 1,576,901 | $7.837M | 0.0% | $6.41 | -15.7% | COM | 019770106 |
| OPTEY | Opthea Limited | 2,691,391 | $7.536M | 0.0% | $11.12 | — | SPONSORED ADS | 68386J208 |
| INSM | Insmed Incorporated | 343,000 | $7.237M | 0.0% | $19.59 | -3.1% | COM PAR $.01 | 457669307 |
| TCRX | TScan Therapeutics, Inc. | 2,784,792 | $6.962M | 0.0% | $6.08 | -55.9% | COM | 89854M101 |
| WHWK | Aadi Bioscience, Inc. | 989,928 | $6.771M | 0.0% | $13.14 | -40.8% | COM | 00032Q104 |
| SERA | Sera Prognostics, Inc. | 1,777,435 | $5.857M | 0.0% | $3.50 | -2.0% | CLASS A COM | 81749D107 |
| ALEC | Alector, Inc. | 964,851 | $5.799M | 0.0% | $12.71 | -45.1% | COM | 014442107 |
| CMPX | Compass Therapeutics, Inc. | 1,557,630 | $4.953M | 0.0% | $3.99 | -21.3% | COM | 20454B104 |
| NTRA | Natera, Inc. | 100,000 | $4.866M | 0.0% | $37.02 | +37.8% | COM | 632307104 |
| MGNX | MacroGenics, Inc. | 892,579 | $4.775M | 0.0% | $14.35 | -57.0% | COM | 556099109 |
| MREO | Mereo BioPharma Group PLC | 3,554,979 | $4.693M | 0.0% | $1.32 | — | SPONSORED ADS | 589492107 |
| — | Aravive, Inc. | 3,261,224 | $4.109M | 0.0% | $1.32 | — | COM | 03890D108 |
| — | Affimed N.V. | 6,596,830 | $3.946M | 0.0% | $4.50 | — | COM | N01045108 |
| — | HOOKIPA Pharma Inc. | 4,425,535 | $3.894M | 0.0% | $2.33 | — | COM | 43906K100 |
| EWTX | Edgewise Therapeutics, Inc. | 500,000 | $3.875M | 0.0% | $32.43 | -74.0% | COM | 28036F105 |
| — | Gracell Biotechnologies Inc. | 1,000,000 | $3.81M | 0.0% | $3.81 | — | SPONSORED ADS | 38406L103 |
| CYPH | Leap Therapeutics, Inc. | 1,172,175 | $3.669M | 0.0% | $5.02 | 0.0% | COM | 52187K200 |
| TLIS | Talis Biomedical Corporation | 7,624,835 | $3.66M | 0.0% | $7.25 | 0.0% | COM | 87424L207 |
| IPSC | Century Therapeutics, Inc. | 1,149,340 | $3.632M | 0.0% | $9.79 | -67.1% | COM | 15673T100 |
| — | Mersana Therapeutics, Inc. | 1,086,115 | $3.573M | 0.0% | $4.11 | — | COM | 59045L106 |
| — | Atreca, Inc. | 3,532,760 | $3.462M | 0.0% | $18.84 | — | CL A COM | 04965G109 |
| — | Neoleukin Therapeutics, Inc. | 3,821,740 | $3.172M | 0.0% | $3.87 | — | COM | 64049K104 |
| DSGN | Design Therapeutics, Inc. | 500,000 | $3.15M | 0.0% | $31.14 | -80.4% | COM | 25056L103 |
| XNCR | Xencor, Inc. | 123,127 | $3.074M | 0.0% | $27.96 | -2.7% | COM | 98401F105 |
| — | Instil Bio, Inc. | 5,273,789 | $2.906M | 0.0% | $18.68 | — | COM | 45783C101 |
| TNGX | Tango Therapeutics, Inc. | 750,000 | $2.49M | 0.0% | $11.99 | -70.0% | COM | 87583X109 |
| PCVX | Vaxcyte, Inc. | 48,885 | $2.441M | 0.0% | $39.24 | +20.8% | COM | 92243G108 |
| — | Achilles Therapeutics plc | 2,557,149 | $2.417M | 0.0% | $16.55 | — | SPONSORED ADS | 00449L102 |
| VERA | Vera Therapeutics, Inc. | 146,464 | $2.351M | 0.0% | $21.52 | -58.0% | CL A | 92337R101 |
| — | Praxis Precision Medicines, Inc. | 1,879,915 | $2.162M | 0.0% | $2.34 | — | COM | 74006W108 |
| — | Aligos Therapeutics, Inc. | 2,076,400 | $2.016M | 0.0% | $24.92 | — | COM | 01626L105 |
| PMVP | PMV Pharmaceuticals, Inc. | 322,024 | $2.016M | 0.0% | $14.45 | -63.7% | COM | 69353Y103 |
| — | iTeos Therapeutics, Inc. | 150,346 | $1.991M | 0.0% | $24.67 | — | COM | 46565G104 |
| — | Vor Biopharma Inc. | 633,848 | $1.959M | 0.0% | $4.75 | — | COM | 929033108 |
| KALA | Kala Pharmaceuticals, Inc. | 116,213 | $1.696M | 0.0% | $10.50 | +47.9% | COM | 483119202 |
| — | Perspective Therapeutics, Inc. | 2,319,286 | $1.549M | 0.0% | $0.67 | — | COM | 46489V104 |
| — | Aeglea BioTherapeutics, Inc. | 3,410,106 | $1.536M | 0.0% | $7.84 | — | COM | 00773J103 |
| — | FibroGen, Inc. | 238,084 | $643K | 0.0% | $16.38 | — | COM | 31572Q808 |
| NKTX | Nkarta, Inc. | 271,329 | $594K | 0.0% | $13.12 | -66.5% | COM | 65487U108 |
| TARA | Protara Therapeutics, Inc. | 199,671 | $477K | 0.0% | $30.96 | -90.4% | COM STK | 74365U107 |
| — | Genetron Holdings Limited | 455,306 | $423K | 0.0% | $13.55 | — | ADS | 37186H100 |
| FHTX | Foghorn Therapeutics Inc. | 45,027 | $317K | 0.0% | $14.37 | -51.4% | COM | 344174107 |
| — | Vincerx Pharma, Inc. | 225,579 | $293K | 0.0% | $16.17 | — | COM | 92731L106 |
| SRZNW | Surrozen, Inc. | 833,333 | $46,000 | 0.0% | $1.14 | — | W EXP 8/11/2026 | 86889P117 |