Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q2 2024 (← Previous) (Next →)
Filing Date: Aug 14, 2024
Total Value: $7.825B (98.1% shares, 1.9% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| INCY | Incyte Corporation | 30,738,524 | $1.863B | 23.8% | $72.80 | -22.2% | COM | 45337C102 |
| ONC | BeiGene, Ltd. | 10,568,897 | $1.508B | 19.3% | $136.93 | — | SPONSORED ADR | 07725L102 |
| ACAD | ACADIA Pharmaceuticals Inc. | 42,877,916 | $697M | 8.9% | $18.93 | -14.7% | COM | 004225108 |
| MDGL | Madrigal Pharmaceuticals, Inc. | 1,974,590 | $553M | 7.1% | $119.77 | +98.7% | COM | 558868105 |
| RVMD | Revolution Medicines, Inc. | 7,569,090 | $294M | 3.8% | $26.62 | +40.4% | COM | 76155X100 |
| RYTM | Rhythm Pharmaceuticals, Inc. | 6,398,365 | $263M | 3.4% | $23.49 | +70.0% | COM | 76243J105 |
| INSM | Insmed Incorporated | 3,576,038 | $240M | 3.1% | $36.94 | +5.0% | COM PAR $.01 | 457669307 |
| BCYC | Bicycle Therapeutics plc | 9,399,960 | $190M | 2.4% | $21.86 | — | SPONSORED ADS | 088786108 |
| SMMT | Summit Therapeutics Inc. | 23,222,222 | $181M | 2.3% | $5.40 | 0.0% | COM | 86627T108 |
| KYMR | Kymera Therapeutics, Inc. | 5,995,928 | $179M | 2.3% | $28.14 | +23.1% | COM | 501575104 |
| EWTX | Edgewise Therapeutics, Inc. | 5,840,059 | $105M | 1.3% | $13.32 | +31.0% | COM | 28036F105 |
| ALKS | Alkermes plc | 4,181,751 | $101M | 1.3% | $24.53 | 0.0% | SHS | G01767105 |
| — | Insmed Incorporated | 42,850,000 | $90.41M | 1.2% | $2.11 | — | Note 0.75% 6/1/2028 | 457669AB5 |
| REPL | Replimune Group, Inc. | 10,045,336 | $90.41M | 1.2% | $14.88 | -53.2% | COM | 76029N106 |
| DNLI | Denali Therapeutics Inc. | 3,731,695 | $86.65M | 1.1% | $23.78 | -19.3% | COM | 24823R105 |
| ABCL | AbCellera Biologics Inc. | 27,525,640 | $81.48M | 1.0% | $21.02 | -82.0% | COM | 00288U106 |
| NRIX | Nurix Therapeutics, Inc. | 3,882,125 | $81.02M | 1.0% | $22.27 | -30.1% | COM | 67080M103 |
| IMTX | Immatics N.V. | 6,443,398 | $74.87M | 1.0% | $10.87 | +3.7% | SHS | N44445109 |
| TRDA | Entrada Therapeutics, Inc. | 4,865,819 | $69.34M | 0.9% | $16.96 | — | COM | 29384C108 |
| RARE | Ultragenyx Pharmaceutical Inc. | 1,466,547 | $60.28M | 0.8% | $65.34 | -34.7% | COM | 90400D108 |
| STOK | Stoke Therapeutics, Inc. | 4,368,443 | $59.02M | 0.8% | $9.12 | +48.0% | COM | 86150R107 |
| — | Insmed Incorporated | 32,887,000 | $56.19M | 0.7% | $1.71 | — | Note 1.75% 1/15/2025 | 457669AA7 |
| KNSA | Kiniksa Pharmaceuticals International, plc | 2,818,323 | $52.62M | 0.7% | $18.73 | 0.0% | ORD SHS CL A | G52694109 |
| IMCR | Immunocore Holdings plc | 1,515,318 | $51.35M | 0.7% | $42.57 | — | ADS | 45258D105 |
| ARGX | argenx SE | 111,904 | $48.12M | 0.6% | $79.01 | — | SPONSORED ADR | 04016X101 |
| KOD | Kodiak Sciences Inc. | 17,310,490 | $40.68M | 0.5% | $30.30 | -88.8% | COM | 50015M109 |
| XENE | Xenon Pharmaceuticals Inc. | 993,679 | $38.74M | 0.5% | $18.51 | +116.0% | COM | 98420N105 |
| PRLD | Prelude Therapeutics Inc. | 10,123,824 | $38.57M | 0.5% | $28.24 | -85.6% | COM | 74065P101 |
| IDYA | IDEAYA Biosciences, Inc. | 1,062,123 | $37.29M | 0.5% | $14.62 | +170.8% | COM | 45166A102 |
| CERS | Cerus Corporation | 19,477,339 | $34.28M | 0.4% | $4.19 | -57.3% | COM | 157085101 |
| SERA | Sera Prognostics, Inc. | 5,434,399 | $32.17M | 0.4% | $3.07 | +191.1% | CLASS A COM | 81749D107 |
| KRYS | Krystal Biotech, Inc. | 169,934 | $31.21M | 0.4% | $34.45 | +387.4% | COM | 501147102 |
| CELC | Celcuity Inc. | 1,874,978 | $30.71M | 0.4% | $14.35 | +16.6% | COM | 15102K100 |
| ROIV | Roivant Sciences Ltd. | 2,798,716 | $29.58M | 0.4% | $8.98 | +22.0% | SHS | G76279101 |
| — | IGM Biosciences, Inc. | 4,090,316 | $28.1M | 0.4% | $15.73 | — | COM | 449585108 |
| — | Cerevel Therapeutics Holdings, Inc. | 683,588 | $27.95M | 0.4% | $42.40 | — | COM | 15678U128 |
| — | Akero Therapeutics, Inc. | 1,097,082 | $25.74M | 0.3% | $32.79 | — | COM | 00973Y108 |
| DYN | Dyne Therapeutics, Inc. | 672,096 | $23.72M | 0.3% | $26.33 | +10.4% | COM | 26818M108 |
| ALMS | Alumis Inc. | 1,562,500 | $20.78M | 0.3% | $13.30 | 0.0% | COM | 022307102 |
| GLUE | Monte Rosa Therapeutics, Inc. | 4,916,095 | $18.39M | 0.2% | $6.49 | -21.5% | COM | 61225M102 |
| — | Merus N.V. | 300,000 | $17.75M | 0.2% | $59.17 | — | COM | N5749R100 |
| NGNE | Neurogene Inc. | 456,015 | $16.59M | 0.2% | $14.32 | +146.3% | COM | 64135M105 |
| TCRX | TScan Therapeutics, Inc. | 2,784,792 | $16.29M | 0.2% | $6.08 | +29.5% | COM | 89854M101 |
| SANA | Sana Biotechnology, Inc. | 2,380,949 | $13M | 0.2% | $4.55 | +74.9% | COM | 799566104 |
| IMVT | Immunovant, Inc. | 464,718 | $12.27M | 0.2% | $23.10 | +23.1% | COM | 45258J102 |
| XNCR | Xencor, Inc. | 545,431 | $10.33M | 0.1% | $22.46 | -4.4% | COM | 98401F105 |
| NMRA | Neumora Therapeutics, Inc. | 1,034,600 | $10.17M | 0.1% | $13.91 | -25.6% | COM | 640979100 |
| FATE | Fate Therapeutics, Inc. | 2,997,772 | $9.833M | 0.1% | $5.48 | -20.1% | COM | 31189P102 |
| — | 2seventy bio, Inc. | 2,497,526 | $9.615M | 0.1% | $18.72 | — | COMMON STOCK | 901384107 |
| BMEA | Biomea Fusion, Inc. | 2,108,949 | $9.49M | 0.1% | $8.56 | +18.7% | COM | 09077A106 |
| CLDX | Celldex Therapeutics, Inc. | 247,644 | $9.165M | 0.1% | $29.41 | +28.3% | COM | 15117B202 |
| TSHA | Taysha Gene Therapies, Inc. | 4,004,756 | $8.971M | 0.1% | $1.91 | +52.0% | COM SHS | 877619106 |
| — | Athira Pharma, Inc. | 3,153,807 | $8.358M | 0.1% | $6.91 | — | COM | 04746L104 |
| — | Verve Therapeutics, Inc. | 1,691,530 | $8.255M | 0.1% | $52.72 | — | COM | 92539P101 |
| RLAY | Relay Therapeutics, Inc. | 1,160,117 | $7.564M | 0.1% | $13.78 | -50.4% | COM | 75943R102 |
| MIRM | Mirum Pharmaceuticals, Inc. | 190,476 | $6.512M | 0.1% | $27.38 | -4.3% | COM | 604749101 |
| TNGX | Tango Therapeutics, Inc. | 750,000 | $6.435M | 0.1% | $11.99 | -35.5% | COM | 87583X109 |
| KALA | KALA BIO, Inc. | 891,335 | $6.32M | 0.1% | $8.21 | -19.6% | COM | 483119202 |
| — | DBV Technologies S.A. | 7,307,131 | $5.853M | 0.1% | $0.80 | — | SPONSORED ADR | 23306J200 |
| DSGN | Design Therapeutics, Inc. | 1,695,294 | $5.679M | 0.1% | $12.27 | -68.2% | COM | 25056L103 |
| CTNM | Contineum Therapeutics, Inc. | 312,500 | $5.503M | 0.1% | $16.10 | 0.0% | CL A | 21217B100 |
| PRAX | Praxis Precision Medicines, Inc. | 131,533 | $5.44M | 0.1% | $44.86 | +5.3% | COM | 74006W207 |
| CRSP | CRISPR Therapeutics AG | 100,000 | $5.401M | 0.1% | $57.84 | 0.0% | NAMEN AKT | H17182108 |
| PRME | Prime Medicine, Inc. | 1,028,466 | $5.286M | 0.1% | $18.06 | -66.4% | COM | 74168J101 |
| CNTA | Centessa Pharmaceuticals plc | 549,212 | $4.959M | 0.1% | $9.03 | — | SPONSORED ADS | 152309100 |
| HOOK | HOOKIPA Pharma Inc. | 8,128,151 | $4.81M | 0.1% | $7.93 | 0.0% | COM | 43906K209 |
| SGMT | Sagimet Biosciences Inc. | 1,381,898 | $4.726M | 0.1% | $9.53 | -51.9% | COM SER A | 786700104 |
| CRNX | Crinetics Pharmaceuticals, Inc. | 103,927 | $4.655M | 0.1% | $46.18 | 0.0% | COM | 22663K107 |
| TLIS | Talis Biomedical Corporation | 508,323 | $4.403M | 0.1% | $7.25 | +22.1% | COM | 87424L207 |
| ALEC | Alector, Inc. | 927,264 | $4.21M | 0.1% | $5.15 | 0.0% | COM | 014442107 |
| OPTEY | Opthea Limited | 2,173,622 | $4.195M | 0.1% | $11.12 | — | SPONSORED ADS | 68386J208 |
| SKYE | Skye Bioscience, Inc. | 500,000 | $4.005M | 0.1% | $11.84 | 0.0% | COM | 83086J200 |
| PCVX | Vaxcyte, Inc. | 48,885 | $3.691M | 0.0% | $39.24 | +73.5% | COM | 92243G108 |
| ARCT | Arcturus Therapeutics Holdings Inc. | 151,329 | $3.685M | 0.0% | $30.32 | 0.0% | COM | 03969T109 |
| — | Generation Bio Co. | 1,206,957 | $3.404M | 0.0% | $3.20 | — | COM | 37148K100 |
| ELVN | Enliven Therapeutics, Inc. | 114,833 | $2.684M | 0.0% | $15.34 | +37.2% | COM | 29337E102 |
| CYPH | Leap Therapeutics, Inc. | 1,172,175 | $2.297M | 0.0% | $5.02 | -47.8% | COM | 52187K200 |
| ADAPY | Adaptimmune Therapeutics plc | 2,343,695 | $2.285M | 0.0% | $5.27 | — | SPONSORED ADR | 00653A107 |
| — | Mersana Therapeutics, Inc. | 1,086,115 | $2.183M | 0.0% | $4.11 | — | COM | 59045L106 |
| IPSC | Century Therapeutics, Inc. | 797,460 | $2.034M | 0.0% | $9.79 | -67.7% | COM | 15673T100 |
| NAMS | NewAmsterdam Pharma Company N.V. | 96,827 | $1.86M | 0.0% | $20.30 | -1.2% | ORDINARY SHARES | N62509109 |
| — | Sage Therapeutics, Inc. | 171,026 | $1.857M | 0.0% | $18.74 | — | COM | 78667J108 |
| VTVT | vTv Therapeutics, Inc. | 97,314 | $1.719M | 0.0% | $12.72 | +86.8% | CL A | 918385204 |
| CMPX | Compass Therapeutics, Inc. | 1,557,630 | $1.558M | 0.0% | $3.99 | -63.4% | COM | 20454B104 |
| TARA | Protara Therapeutics, Inc. | 536,832 | $1.117M | 0.0% | $13.35 | -78.1% | COM STK | 74365U107 |
| — | Aerovate Therapeutics, Inc. | 628,939 | $1.044M | 0.0% | $21.15 | — | COM | 008064107 |
| PFE | Pfizer Inc. | 35,000 | $979K | 0.0% | $26.40 | -6.2% | COM | 717081103 |
| — | Achilles Therapeutics plc | 1,108,767 | $904K | 0.0% | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | Aligos Therapeutics, Inc. | 2,076,400 | $727K | 0.0% | $24.92 | — | COM | 01626L105 |
| PMVP | PMV Pharmaceuticals, Inc. | 322,024 | $522K | 0.0% | $14.45 | -87.5% | COM | 69353Y103 |
| BCRX | BioCryst Pharmaceuticals, Inc. | 75,778 | $468K | 0.0% | $6.35 | -13.1% | COM | 09058V103 |
| ACRV | Acrivon Therapeutics, Inc. | 52,885 | $307K | 0.0% | $4.64 | +73.5% | COMMON STOCK | 004890109 |
| FHTX | Foghorn Therapeutics Inc. | 45,027 | $259K | 0.0% | $14.37 | -58.6% | COM | 344174107 |
| TYRA | Tyra Biosciences, Inc. | 10,607 | $170K | 0.0% | $12.95 | +33.0% | COM | 90240B106 |
| SRZNW | Surrozen, Inc. | 833,333 | $13,833 | 0.0% | $1.14 | — | W EXP 8/11/2026 | 86889P117 |