RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value: $1.011B (100.0% shares, 0.0% debt)

Holdings (37)

— ACHILLION PHARMACEUTICALS INC 12.0%

Value $121M Shares 11,222,893 Share Price $10.79 Est. Cost/Share $6.36 Unrealized @ Report Date —

WVE WAVE LIFE SCIENCES LTD 11.2%

Value $113M Shares 7,088,651 Share Price $15.95 Est. Cost/Share $15.68 Unrealized @ Report Date 0.0%

— DYAX CORP 10.1%

Value $102M Shares 2,717,618 Share Price $37.62 Est. Cost/Share $10.04 Unrealized @ Report Date —

— AXOVANT SCIENCES LTD 8.9%

Value $90.15M Shares 5,000,000 Share Price $18.03 Est. Cost/Share $20.38 Unrealized @ Report Date —

ACRS ACLARIS THERAPEUTICS INC 6.8%

Value $69.09M Shares 2,564,553 Share Price $26.94 * Est. Cost/Share $19.34 Unrealized @ Report Date 0.0%

TGTX TG THERAPEUTICS INC 3.3%

Value $33.57M Shares 2,813,779 Share Price $11.93 * Est. Cost/Share $10.99 Unrealized @ Report Date +15.0%

— ZOGENIX INC 3.3%

Value $33.21M Shares 2,253,237 Share Price $14.74 Est. Cost/Share $13.82 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 3.2%

Value $31.93M Shares 3,094,064 Share Price $10.32 * Est. Cost/Share $9.58 Unrealized @ Report Date +3.8%

ASND ASCENDIS PHARMA A S 3.0%

Value $30.62M Shares 1,671,447 Share Price $18.32 Est. Cost/Share $17.61 Unrealized @ Report Date —

— REGULUS THERAPEUTICS INC 3.0%

Value $30.37M Shares 3,482,924 Share Price $8.72 Est. Cost/Share $15.20 Unrealized @ Report Date —

CHRS COHERUS BIOSCIENCES INC 2.9%

Value $29.21M Shares 1,272,048 Share Price $22.96 * Est. Cost/Share $14.11 Unrealized @ Report Date +82.4%

— DICERNA PHARMACEUTICALS INC 2.9%

Value $28.83M Shares 2,428,571 Share Price $11.87 Est. Cost/Share $28.25 Unrealized @ Report Date —

COLL COLLEGIUM PHARMACEUTICAL INC 2.3%

Value $23.59M Shares 857,683 Share Price $27.50 * Est. Cost/Share $17.29 Unrealized @ Report Date +21.8%

— BLUEPRINT MEDICINES CORP 2.3%

Value $23.14M Shares 878,348 Share Price $26.34 Est. Cost/Share $26.49 Unrealized @ Report Date —

— PROTEON THERAPEUTICS INC 2.3%

Value $22.91M Shares 1,476,931 Share Price $15.51 Est. Cost/Share $11.67 Unrealized @ Report Date —

— STRONGBRIDGE BIOPHARMA PLC 2.0%

Value $20.45M Shares 2,690,702 Share Price $7.60 Est. Cost/Share $7.60 Unrealized @ Report Date —

— AQUINOX PHARMACEUTICALS INC 2.0%

Value $20.22M Shares 1,619,977 Share Price $12.48 Est. Cost/Share $13.98 Unrealized @ Report Date —

SGMO SANGAMO BIOSCIENCES INC 2.0%

Value $20.2M Shares 2,212,036 Share Price $9.13 * Est. Cost/Share $8.61 Unrealized @ Report Date -10.5%

— CIDARA THERAPEUTICS INC 2.0%

Value $20.15M Shares 1,174,219 Share Price $17.16 Est. Cost/Share $13.98 Unrealized @ Report Date —

— ALCOBRA LTD 1.9%

Value $19.05M Shares 3,032,911 Share Price $6.28 Est. Cost/Share $6.39 Unrealized @ Report Date —

— ARENA PHARMACEUTICAL S INC 1.6%

Value $16.56M Shares 8,714,482 Share Price $1.90 Est. Cost/Share $1.90 Unrealized @ Report Date —

— GLOBAL BLOOD THERAPEUTICS INC 1.5%

Value $14.78M Shares 457,142 Share Price $32.33 Est. Cost/Share $42.16 Unrealized @ Report Date —

— AIMMUNE THERAPEUTICS INC 1.4%

Value $14.58M Shares 790,200 Share Price $18.45 Est. Cost/Share $25.32 Unrealized @ Report Date —

— DIMENSION THERAPEUTICS INC 1.2%

Value $12.27M Shares 1,087,930 Share Price $11.28 Est. Cost/Share $11.28 Unrealized @ Report Date —

ARDX ARDELYX INC 1.0%

Value $10.36M Shares 571,444 Share Price $18.12 * Est. Cost/Share $12.61 Unrealized @ Report Date +47.7%

— PRONAI THERAPEUTICS INC 0.9%

Value $9.099M Shares 604,982 Share Price $15.04 Est. Cost/Share $20.52 Unrealized @ Report Date —

NTRA NATERA INC 0.8%

Value $8.462M Shares 783,520 Share Price $10.80 * Est. Cost/Share $16.90 Unrealized @ Report Date -43.7%

— TENAX THERAPEUTICS INC 0.8%

Value $7.838M Shares 2,389,700 Share Price $3.28 Est. Cost/Share $3.92 Unrealized @ Report Date —

— VITAE PHARMACEUTICALS INC 0.6%

Value $5.813M Shares 321,161 Share Price $18.10 Est. Cost/Share $11.01 Unrealized @ Report Date —

— ZYNERBA PHARMACEUTICALS INC 0.5%

Value $5.107M Shares 507,191 Share Price $10.07 Est. Cost/Share $14.31 Unrealized @ Report Date —

— APPLIED GENETIC TECHNOL CORP 0.5%

Value $4.816M Shares 236,059 Share Price $20.40 Est. Cost/Share $16.68 Unrealized @ Report Date —

— NIVALIS THERAPEUTICS INC 0.5%

Value $4.744M Shares 612,863 Share Price $7.74 Est. Cost/Share $15.15 Unrealized @ Report Date —

— AKARI THERAPEUTICS PLC 0.4%

Value $3.827M Shares 263,921 Share Price $14.50 Est. Cost/Share $24.00 Unrealized @ Report Date —

— ARCA BIOPHARMA INC 0.4%

Value $3.619M Shares 778,211 Share Price $4.65 Est. Cost/Share $4.96 Unrealized @ Report Date —

— DERMA SCIENCES INC 0.3%

Value $2.93M Shares 641,236 Share Price $4.57 Est. Cost/Share $4.57 Unrealized @ Report Date —

— NEURODERM LTD 0.2%

Value $2.467M Shares 144,671 Share Price $17.05 Est. Cost/Share $20.67 Unrealized @ Report Date —

— AMPLIPHI BIOSCIENCES CORP 0.0%

Value $213K Shares 53,600 Share Price $3.97 Est. Cost/Share $3.95 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
—	ACHILLION PHARMACEUTICALS INC	11,222,893	$121M	12.0%	$10.79	$6.36	—	COM	00448Q201
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$113M	11.2%	$15.95	$15.68	0.0%	SHS	Y95308105
—	DYAX CORP	2,717,618	$102M	10.1%	$37.62	$10.04	—	COM	26746E103
—	AXOVANT SCIENCES LTD	5,000,000	$90.15M	8.9%	$18.03	$20.38	—	COM	G0750W104
ACRS	ACLARIS THERAPEUTICS INC	2,564,553	$69.09M	6.8%	$26.94 *	$19.34	0.0%	COM	00461U105
TGTX	TG THERAPEUTICS INC	2,813,779	$33.57M	3.3%	$11.93 *	$10.99	+15.0%	COM	88322Q108
—	ZOGENIX INC	2,253,237	$33.21M	3.3%	$14.74	$13.82	—	COM NEW	98978L204
BCRX	BIOCRYST PHARMACEUTICALS	3,094,064	$31.93M	3.2%	$10.32 *	$9.58	+3.8%	COM	09058V103
ASND	ASCENDIS PHARMA A S	1,671,447	$30.62M	3.0%	$18.32	$17.61	—	SPONSORED ADR	04351P101
—	REGULUS THERAPEUTICS INC	3,482,924	$30.37M	3.0%	$8.72	$15.20	—	COM	75915K101
CHRS	COHERUS BIOSCIENCES INC	1,272,048	$29.21M	2.9%	$22.96 *	$14.11	+82.4%	COM	19249H103
—	DICERNA PHARMACEUTICALS INC	2,428,571	$28.83M	2.9%	$11.87	$28.25	—	COM	253031108
COLL	COLLEGIUM PHARMACEUTICAL INC	857,683	$23.59M	2.3%	$27.50 *	$17.29	+21.8%	COM	19459J104
—	BLUEPRINT MEDICINES CORP	878,348	$23.14M	2.3%	$26.34	$26.49	—	COM	09627Y109
—	PROTEON THERAPEUTICS INC	1,476,931	$22.91M	2.3%	$15.51	$11.67	—	COM	74371L109
—	STRONGBRIDGE BIOPHARMA PLC	2,690,702	$20.45M	2.0%	$7.60	$7.60	—	SHS USD	G85347105
—	AQUINOX PHARMACEUTICALS INC	1,619,977	$20.22M	2.0%	$12.48	$13.98	—	COM	03842B101
SGMO	SANGAMO BIOSCIENCES INC	2,212,036	$20.2M	2.0%	$9.13 *	$8.61	-10.5%	COM	800677106
—	CIDARA THERAPEUTICS INC	1,174,219	$20.15M	2.0%	$17.16	$13.98	—	COM	171757107
—	ALCOBRA LTD	3,032,911	$19.05M	1.9%	$6.28	$6.39	—	SHS	M2239P109
—	ARENA PHARMACEUTICAL S INC	8,714,482	$16.56M	1.6%	$1.90	$1.90	—	COM	040047102
—	GLOBAL BLOOD THERAPEUTICS INC	457,142	$14.78M	1.5%	$32.33	$42.16	—	COM	37890U108
—	AIMMUNE THERAPEUTICS INC	790,200	$14.58M	1.4%	$18.45	$25.32	—	COM	00900T107
—	DIMENSION THERAPEUTICS INC	1,087,930	$12.27M	1.2%	$11.28	$11.28	—	COM	25433V105
ARDX	ARDELYX INC	571,444	$10.36M	1.0%	$18.12 *	$12.61	+47.7%	COM	039697107
—	PRONAI THERAPEUTICS INC	604,982	$9.099M	0.9%	$15.04	$20.52	—	COM	74346L101
NTRA	NATERA INC	783,520	$8.462M	0.8%	$10.80 *	$16.90	-43.7%	COM	632307104
—	TENAX THERAPEUTICS INC	2,389,700	$7.838M	0.8%	$3.28	$3.92	—	COM	88032L100
—	VITAE PHARMACEUTICALS INC	321,161	$5.813M	0.6%	$18.10	$11.01	—	COM	92847N103
—	ZYNERBA PHARMACEUTICALS INC	507,191	$5.107M	0.5%	$10.07	$14.31	—	COM	98986X109
—	APPLIED GENETIC TECHNOL CORP	236,059	$4.816M	0.5%	$20.40	$16.68	—	COM	03820J100
—	NIVALIS THERAPEUTICS INC	612,863	$4.744M	0.5%	$7.74	$15.15	—	COM	65481J109
—	AKARI THERAPEUTICS PLC	263,921	$3.827M	0.4%	$14.50	$24.00	—	SPONSORED ADR	00972G108
—	ARCA BIOPHARMA INC	778,211	$3.619M	0.4%	$4.65	$4.96	—	COM PAR$.001	00211Y407
—	DERMA SCIENCES INC	641,236	$2.93M	0.3%	$4.57	$4.57	—	COM PAR $.01	249827502
—	NEURODERM LTD	144,671	$2.467M	0.2%	$17.05	$20.67	—	ORD SHS	M74231107
—	AMPLIPHI BIOSCIENCES CORP	53,600	$213K	0.0%	$3.97	$3.95	—	COM NEW	03211P202