RA CAPITAL MANAGEMENT, L.P. Diversified Active

CIK: 0001346824 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value ($000): $1,010,538 (100.0% shares, 0.0% debt)

Holdings (37)

— ACHILLION PHARMACEUTICALS INC 12.0%

Value ($000) $121,095 Shares 11,222,893 Est. Cost $6.36 Unrealized —

WVE WAVE LIFE SCIENCES LTD 11.2%

Value ($000) $113,064 Shares 7,088,651 Est. Cost $15.68 Unrealized 0.0%

— DYAX CORP 10.1%

Value ($000) $102,237 Shares 2,717,618 Est. Cost $10.04 Unrealized —

— AXOVANT SCIENCES LTD 8.9%

Value ($000) $90,150 Shares 5,000,000 Est. Cost $20.38 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 6.8%

Value ($000) $69,089 Shares 2,564,553 Est. Cost $19.34 Unrealized 0.0%

TGTX TG THERAPEUTICS INC 3.3%

Value ($000) $33,568 Shares 2,813,779 Est. Cost $10.99 Unrealized +15.0%

— ZOGENIX INC 3.3%

Value ($000) $33,213 Shares 2,253,237 Est. Cost $13.82 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 3.2%

Value ($000) $31,931 Shares 3,094,064 Est. Cost $9.58 Unrealized +3.8%

ASND ASCENDIS PHARMA A S 3.0%

Value ($000) $30,621 Shares 1,671,447 Est. Cost $17.61 Unrealized —

— REGULUS THERAPEUTICS INC 3.0%

Value ($000) $30,371 Shares 3,482,924 Est. Cost $15.20 Unrealized —

CHRS COHERUS BIOSCIENCES INC 2.9%

Value ($000) $29,206 Shares 1,272,048 Est. Cost $14.11 Unrealized +82.4%

— DICERNA PHARMACEUTICALS INC 2.9%

Value ($000) $28,827 Shares 2,428,571 Est. Cost $28.25 Unrealized —

COLL COLLEGIUM PHARMACEUTICAL INC 2.3%

Value ($000) $23,586 Shares 857,683 Est. Cost $17.29 Unrealized +21.8%

— BLUEPRINT MEDICINES CORP 2.3%

Value ($000) $23,136 Shares 878,348 Est. Cost $26.49 Unrealized —

— PROTEON THERAPEUTICS INC 2.3%

Value ($000) $22,907 Shares 1,476,931 Est. Cost $11.67 Unrealized —

— STRONGBRIDGE BIOPHARMA PLC 2.0%

Value ($000) $20,449 Shares 2,690,702 Est. Cost $7.60 Unrealized —

— AQUINOX PHARMACEUTICALS INC 2.0%

Value ($000) $20,217 Shares 1,619,977 Est. Cost $13.98 Unrealized —

SGMO SANGAMO BIOSCIENCES INC 2.0%

Value ($000) $20,196 Shares 2,212,036 Est. Cost $8.61 Unrealized -10.5%

— CIDARA THERAPEUTICS INC 2.0%

Value ($000) $20,150 Shares 1,174,219 Est. Cost $13.98 Unrealized —

— ALCOBRA LTD 1.9%

Value ($000) $19,047 Shares 3,032,911 Est. Cost $6.39 Unrealized —

— ARENA PHARMACEUTICAL S INC 1.6%

Value ($000) $16,558 Shares 8,714,482 Est. Cost $1.90 Unrealized —

— GLOBAL BLOOD THERAPEUTICS INC 1.5%

Value ($000) $14,779 Shares 457,142 Est. Cost $42.16 Unrealized —

— AIMMUNE THERAPEUTICS INC 1.4%

Value ($000) $14,579 Shares 790,200 Est. Cost $25.32 Unrealized —

— DIMENSION THERAPEUTICS INC 1.2%

Value ($000) $12,272 Shares 1,087,930 Est. Cost $11.28 Unrealized —

ARDX ARDELYX INC 1.0%

Value ($000) $10,355 Shares 571,444 Est. Cost $12.61 Unrealized +47.7%

— PRONAI THERAPEUTICS INC 0.9%

Value ($000) $9,099 Shares 604,982 Est. Cost $20.52 Unrealized —

NTRA NATERA INC 0.8%

Value ($000) $8,462 Shares 783,520 Est. Cost $16.90 Unrealized -43.7%

— TENAX THERAPEUTICS INC 0.8%

Value ($000) $7,838 Shares 2,389,700 Est. Cost $3.92 Unrealized —

— VITAE PHARMACEUTICALS INC 0.6%

Value ($000) $5,813 Shares 321,161 Est. Cost $11.01 Unrealized —

— ZYNERBA PHARMACEUTICALS INC 0.5%

Value ($000) $5,107 Shares 507,191 Est. Cost $14.31 Unrealized —

— APPLIED GENETIC TECHNOL CORP 0.5%

Value ($000) $4,816 Shares 236,059 Est. Cost $16.68 Unrealized —

— NIVALIS THERAPEUTICS INC 0.5%

Value ($000) $4,744 Shares 612,863 Est. Cost $15.15 Unrealized —

— AKARI THERAPEUTICS PLC 0.4%

Value ($000) $3,827 Shares 263,921 Est. Cost $24.00 Unrealized —

— ARCA BIOPHARMA INC 0.4%

Value ($000) $3,619 Shares 778,211 Est. Cost $4.96 Unrealized —

— DERMA SCIENCES INC 0.3%

Value ($000) $2,930 Shares 641,236 Est. Cost $4.57 Unrealized —

— NEURODERM LTD 0.2%

Value ($000) $2,467 Shares 144,671 Est. Cost $20.67 Unrealized —

— AMPLIPHI BIOSCIENCES CORP 0.0%

Value ($000) $213 Shares 53,600 Est. Cost $3.95 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	ACHILLION PHARMACEUTICALS INC	11,222,893	$121,095	12.0%	$6.36	—	COM	00448Q201
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$113,064	11.2%	$15.68	0.0%	SHS	Y95308105
—	DYAX CORP	2,717,618	$102,237	10.1%	$10.04	—	COM	26746E103
—	AXOVANT SCIENCES LTD	5,000,000	$90,150	8.9%	$20.38	—	COM	G0750W104
ACRS	ACLARIS THERAPEUTICS INC	2,564,553	$69,089	6.8%	$19.34	0.0%	COM	00461U105
TGTX	TG THERAPEUTICS INC	2,813,779	$33,568	3.3%	$10.99	+15.0%	COM	88322Q108
—	ZOGENIX INC	2,253,237	$33,213	3.3%	$13.82	—	COM NEW	98978L204
BCRX	BIOCRYST PHARMACEUTICALS	3,094,064	$31,931	3.2%	$9.58	+3.8%	COM	09058V103
ASND	ASCENDIS PHARMA A S	1,671,447	$30,621	3.0%	$17.61	—	SPONSORED ADR	04351P101
—	REGULUS THERAPEUTICS INC	3,482,924	$30,371	3.0%	$15.20	—	COM	75915K101
CHRS	COHERUS BIOSCIENCES INC	1,272,048	$29,206	2.9%	$14.11	+82.4%	COM	19249H103
—	DICERNA PHARMACEUTICALS INC	2,428,571	$28,827	2.9%	$28.25	—	COM	253031108
COLL	COLLEGIUM PHARMACEUTICAL INC	857,683	$23,586	2.3%	$17.29	+21.8%	COM	19459J104
—	BLUEPRINT MEDICINES CORP	878,348	$23,136	2.3%	$26.49	—	COM	09627Y109
—	PROTEON THERAPEUTICS INC	1,476,931	$22,907	2.3%	$11.67	—	COM	74371L109
—	STRONGBRIDGE BIOPHARMA PLC	2,690,702	$20,449	2.0%	$7.60	—	SHS USD	G85347105
—	AQUINOX PHARMACEUTICALS INC	1,619,977	$20,217	2.0%	$13.98	—	COM	03842B101
SGMO	SANGAMO BIOSCIENCES INC	2,212,036	$20,196	2.0%	$8.61	-10.5%	COM	800677106
—	CIDARA THERAPEUTICS INC	1,174,219	$20,150	2.0%	$13.98	—	COM	171757107
—	ALCOBRA LTD	3,032,911	$19,047	1.9%	$6.39	—	SHS	M2239P109
—	ARENA PHARMACEUTICAL S INC	8,714,482	$16,558	1.6%	$1.90	—	COM	040047102
—	GLOBAL BLOOD THERAPEUTICS INC	457,142	$14,779	1.5%	$42.16	—	COM	37890U108
—	AIMMUNE THERAPEUTICS INC	790,200	$14,579	1.4%	$25.32	—	COM	00900T107
—	DIMENSION THERAPEUTICS INC	1,087,930	$12,272	1.2%	$11.28	—	COM	25433V105
ARDX	ARDELYX INC	571,444	$10,355	1.0%	$12.61	+47.7%	COM	039697107
—	PRONAI THERAPEUTICS INC	604,982	$9,099	0.9%	$20.52	—	COM	74346L101
NTRA	NATERA INC	783,520	$8,462	0.8%	$16.90	-43.7%	COM	632307104
—	TENAX THERAPEUTICS INC	2,389,700	$7,838	0.8%	$3.92	—	COM	88032L100
—	VITAE PHARMACEUTICALS INC	321,161	$5,813	0.6%	$11.01	—	COM	92847N103
—	ZYNERBA PHARMACEUTICALS INC	507,191	$5,107	0.5%	$14.31	—	COM	98986X109
—	APPLIED GENETIC TECHNOL CORP	236,059	$4,816	0.5%	$16.68	—	COM	03820J100
—	NIVALIS THERAPEUTICS INC	612,863	$4,744	0.5%	$15.15	—	COM	65481J109
—	AKARI THERAPEUTICS PLC	263,921	$3,827	0.4%	$24.00	—	SPONSORED ADR	00972G108
—	ARCA BIOPHARMA INC	778,211	$3,619	0.4%	$4.96	—	COM PAR$.001	00211Y407
—	DERMA SCIENCES INC	641,236	$2,930	0.3%	$4.57	—	COM PAR $.01	249827502
—	NEURODERM LTD	144,671	$2,467	0.2%	$20.67	—	ORD SHS	M74231107
—	AMPLIPHI BIOSCIENCES CORP	53,600	$213	0.0%	$3.95	—	COM NEW	03211P202