Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q3 2021 (← Previous) (Next →)
Filing Date: Nov 15, 2021
Total Value: $4.756B (98.9% shares, 1.1% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| AGL | AGILON HEALTH INC | 7,075,000 | $185M | 3.9% | $35.03 | -2.5% | COM | 00857U107 |
| HUM | HUMANA INC | 342,000 | $133M | 2.8% | $346.48 | +17.4% | COM | 444859102 |
| ALGN | ALIGN TECHNOLOGY INC | 200,000 | $133M | 2.8% | $304.27 | +123.2% | COM | 016255101 |
| PODD | INSULET CORP | 437,566 | $124M | 2.6% | $162.03 | +76.0% | COM | 45784P101 |
| ISRG | INTUITIVE SURGICAL INC | 120,000 | $119M | 2.5% | $105.96 | +216.9% | COM NEW | 46120E602 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,556,179 | $118M | 2.5% | $42.90 | +12.6% | COM | 00847X104 |
| ZLAB | ZAI LAB LTD | 1,077,750 | $114M | 2.4% | $61.95 | — | ADR | 98887Q104 |
| IDXX | IDEXX LABS INC | 180,000 | $112M | 2.4% | $292.33 | +129.9% | COM | 45168D104 |
| HCA | HCA HEALTHCARE INC | 450,000 | $109M | 2.3% | $96.26 | +144.5% | COM | 40412C101 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,051,500 | $101M | 2.1% | $73.81 | +28.0% | COM | 64125C109 |
| ARGX | ARGENX SE | 315,000 | $95.13M | 2.0% | $135.42 | — | SPONSORED ADR | 04016X101 |
| NVAX | NOVAVAX INC | 455,000 | $94.33M | 2.0% | $40.40 | +445.5% | COM NEW | 670002401 |
| UNH | UNITEDHEALTH GROUP INC | 240,000 | $93.78M | 2.0% | $189.39 | +103.2% | COM | 91324P102 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,445,155 | $90.64M | 1.9% | $42.31 | — | ADS | 45258D105 |
| — | BLUEPRINT MEDICINES CORP | 849,659 | $87.35M | 1.8% | $72.65 | — | COM | 09627Y109 |
| — | HORIZON THERAPEUTICS PUB L | 702,000 | $76.9M | 1.6% | $81.17 | — | SHS | G46188101 |
| FRPT | FRESHPET INC | 527,000 | $75.2M | 1.6% | $53.76 | +166.0% | COM | 358039105 |
| — | INVITAE CORP | 2,605,829 | $74.08M | 1.6% | $24.00 | — | COM | 46185L103 |
| — | NEVRO CORP | 635,700 | $73.98M | 1.6% | $104.34 | — | COM | 64157F103 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 801,109 | $72.25M | 1.5% | $70.87 | +27.5% | COM | 90400D108 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,803,232 | $68.46M | 1.4% | $10.72 | +49.5% | COM | 00461U105 |
| EW | EDWARDS LIFESCIENCES CORP | 582,000 | $65.89M | 1.4% | $59.31 | +92.4% | COM | 28176E108 |
| ASND | ASCENDIS PHARMA A/S | 400,000 | $63.76M | 1.3% | $83.68 | — | SPONSORED ADR | 04351P101 |
| — | MIRATI THERAPEUTICS INC | 353,514 | $62.54M | 1.3% | $83.63 | — | COM | 60468T105 |
| PHR | PHREESIA INC | 970,000 | $59.85M | 1.3% | $31.31 | +113.1% | COM | 71944F106 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 311,000 | $58.72M | 1.2% | $89.51 | +109.6% | COM | 02043Q107 |
| EVH | EVOLENT HEALTH INC | 1,875,000 | $58.13M | 1.2% | $19.62 | +22.3% | CL A | 30050B101 |
| PCRX | PACIRA BIOSCIENCES INC | 1,000,000 | $56M | 1.2% | $48.35 | +19.2% | COM | 695127100 |
| EXAS | EXACT SCIENCES CORP | 570,000 | $54.41M | 1.1% | $56.53 | +86.8% | COM | 30063P105 |
| PRTA | PROTHENA CORP PLC | 710,430 | $50.6M | 1.1% | $11.75 | +428.6% | SHS | G72800108 |
| TFX | TELEFLEX INCORPORATED | 130,000 | $48.95M | 1.0% | $242.14 | +56.0% | COM | 879369106 |
| — | KARUNA THERAPEUTICS INC | 391,917 | $47.94M | 1.0% | $68.99 | — | COM | 48576A100 |
| ARVN | ARVINAS INC | 577,500 | $47.46M | 1.0% | $32.84 | +169.1% | COM | 04335A105 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,600,589 | $47.22M | 1.0% | $21.36 | — | COM | 15678U128 |
| — | SHOCKWAVE MED INC | 220,000 | $45.29M | 1.0% | $50.28 | — | COM | 82489T104 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 710,000 | $45.28M | 1.0% | $45.06 | +40.1% | COM | 00404A109 |
| — | VERVE THERAPEUTICS INC | 962,826 | $45.25M | 1.0% | $60.25 | — | COM | 92539P101 |
| KYMR | KYMERA THERAPEUTICS INC | 732,927 | $43.05M | 0.9% | $34.51 | +68.0% | COM | 501575104 |
| HCAT | HEALTH CATALYST INC | 850,000 | $42.51M | 0.9% | $35.51 | +53.6% | COM | 42225T107 |
| — | SEAGEN INC | 250,000 | $42.45M | 0.9% | $175.14 | — | COM | 81181C104 |
| PEN | PENUMBRA INC | 147,500 | $39.31M | 0.8% | $55.16 | +387.3% | COM | 70975L107 |
| — | ACCOLADE INC | 923,000 | $38.92M | 0.8% | $42.22 | — | COM | 00437E102 |
| EHC | ENCOMPASS HEALTH CORP | 500,000 | $37.52M | 0.8% | $45.98 | +30.6% | COM | 29261A100 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,496,817 | $36.3M | 0.8% | $24.60 | -25.3% | COM | 89422G107 |
| BAX | BAXTER INTL INC | 450,000 | $36.19M | 0.8% | $71.56 | 0.0% | COM | 071813109 |
| WRBY | WARBY PARKER INC | 650,000 | $34.48M | 0.7% | $53.77 | 0.0% | CL A COM | 93403J106 |
| — | GRAPHITE BIO INC | 2,076,710 | $34.04M | 0.7% | $30.73 | — | COM | 38870X104 |
| — | INTERSECT ENT INC | 1,220,000 | $33.18M | 0.7% | $22.46 | — | COM | 46071F103 |
| SRPT | SAREPTA THERAPEUTICS INC | 350,000 | $32.37M | 0.7% | $55.80 | +38.0% | COM | 803607100 |
| — | ALLAKOS INC | 305,706 | $32.37M | 0.7% | $73.38 | — | COM | 01671P100 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,525,623 | $30.39M | 0.6% | $12.91 | +26.0% | COM | 604749101 |
| — | COVETRUS INC | 1,623,500 | $29.45M | 0.6% | $21.21 | — | COM | 22304C100 |
| IMRX | IMMUNEERING CORP | 1,089,816 | $28.93M | 0.6% | $26.87 | 0.0% | CLASS A COM | 45254E107 |
| — | SIERRA ONCOLOGY INC | 1,313,997 | $28.8M | 0.6% | $17.77 | — | COM NEW | 82640U404 |
| — | MERSANA THERAPEUTICS INC | 3,020,702 | $28.48M | 0.6% | $15.97 | — | COM | 59045L106 |
| — | CYTOKINETICS INC | 8,000,000 | $28.32M | 0.6% | $1.32 | — | NOTE 4.000%11/1 | 23282WAA8 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,429,921 | $27.47M | 0.6% | $6.81 | — | COM NEW | 268158201 |
| AVIR | ATEA PHARMACEUTICALS INC | 750,307 | $26.31M | 0.6% | $32.23 | -14.0% | COM | 04683R106 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 448,000 | $26.23M | 0.6% | $55.70 | -4.9% | COM | 450056106 |
| DXCM | DEXCOM INC | 46,500 | $25.43M | 0.5% | $95.92 | +31.5% | COM | 252131107 |
| LUNG | PULMONX CORP | 700,000 | $25.19M | 0.5% | $48.60 | -19.0% | COM | 745848101 |
| GH | GUARDANT HEALTH INC | 200,000 | $25M | 0.5% | $42.73 | +178.1% | COM | 40131M109 |
| LFST | LIFESTANCE HEALTH GROUP INC | 1,687,500 | $24.47M | 0.5% | $25.62 | -24.8% | COM | 53228F101 |
| CGEM | CULLINAN ONCOLOGY INC | 1,075,912 | $24.28M | 0.5% | $40.60 | -34.1% | COM | 230031106 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 1,579,191 | $23.47M | 0.5% | $16.64 | 0.0% | COM | 00509G209 |
| — | ABCAM PLC | 1,147,588 | $23.26M | 0.5% | $21.14 | — | ADS | 000380204 |
| WHWK | AADI BIOSCIENCES INC | 764,701 | $22.46M | 0.5% | $30.48 | 0.0% | COM | 00032Q104 |
| — | AMARIN CORP PLC | 4,320,000 | $22.03M | 0.5% | $4.93 | — | SPONS ADR NEW | 023111206 |
| — | ICOSAVAX INC | 734,215 | $21.73M | 0.5% | $29.59 | — | COM | 45114M109 |
| CNMD | CONMED CORP | 162,500 | $21.26M | 0.4% | $109.65 | +14.7% | COM | 207410101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 262,500 | $20.95M | 0.4% | $41.45 | +108.4% | COM | 558868105 |
| — | BOLT BIOTHERAPEUTICS INC | 1,649,248 | $20.86M | 0.4% | $31.91 | — | COM | 097702104 |
| NVCR | NOVOCURE LTD | 175,000 | $20.33M | 0.4% | $37.58 | +302.3% | ORD SHS | G6674U108 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 253,500 | $19.59M | 0.4% | $85.83 | -8.1% | COM | 09061G101 |
| — | OAK STR HEALTH INC | 441,000 | $18.76M | 0.4% | $53.12 | — | COM | 67181A107 |
| — | EPIZYME INC | 3,593,885 | $18.4M | 0.4% | $12.21 | — | COM | 29428V104 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 900,000 | $17.77M | 0.4% | $15.97 | +35.4% | COM | 19459J104 |
| — | RIGEL PHARMACEUTICALS INC | 4,793,400 | $17.4M | 0.4% | $2.87 | — | COM NEW | 766559603 |
| SPRO | SPERO THERAPEUTICS INC | 941,543 | $17.33M | 0.4% | $11.82 | +35.8% | COM | 84833T103 |
| — | GOSSAMER BIO INC | 15,573,000 | $16.25M | 0.3% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| LEGN | LEGEND BIOTECH CORP | 315,218 | $15.94M | 0.3% | $38.05 | — | SPONSORED ADS | 52490G102 |
| — | AMRYT PHARMA PLC | 1,295,225 | $15.6M | 0.3% | $12.05 | — | SPONSORED ADS | 03217L106 |
| KURA | KURA ONCOLOGY INC | 822,500 | $15.4M | 0.3% | $32.93 | -42.8% | COM | 50127T109 |
| RLAY | RELAY THERAPEUTICS INC | 469,560 | $14.8M | 0.3% | $35.76 | -5.9% | COM | 75943R102 |
| ANAB | ANAPTYSBIO INC | 535,832 | $14.53M | 0.3% | $28.24 | -10.1% | COM | 032724106 |
| — | PROMETHEUS BIOSCIENCES INC | 610,136 | $14.47M | 0.3% | $18.60 | — | COM | 74349U108 |
| — | BRIGHT HEALTH GROUP INC | 1,765,000 | $14.4M | 0.3% | $17.16 | — | COM | 10920V107 |
| — | LEAP THERAPEUTICS INC | 3,508,270 | $14.07M | 0.3% | $4.01 | — | COM | 52187K101 |
| NKTX | NKARTA INC | 503,148 | $13.99M | 0.3% | $29.49 | +7.4% | COM | 65487U108 |
| BMEA | BIOMEA FUSION INC | 1,165,582 | $13.95M | 0.3% | $17.65 | -27.9% | COM | 09077A106 |
| AUPH | AURINIA PHARMACEUTICALS INC | 613,269 | $13.57M | 0.3% | $14.49 | +9.5% | COM | 05156V102 |
| MGNX | MACROGENICS INC | 641,816 | $13.44M | 0.3% | $23.52 | +2.4% | COM | 556099109 |
| — | VINCERX PHARMA INC | 800,295 | $12.94M | 0.3% | $16.17 | — | COM NEW | 92731L106 |
| FULC | FULCRUM THERAPEUTICS INC | 455,290 | $12.84M | 0.3% | $18.95 | 0.0% | COM | 359616109 |
| WST | WEST PHARMACEUTICAL SVSC INC | 30,000 | $12.74M | 0.3% | $112.53 | +270.5% | COM | 955306105 |
| — | AKERO THERAPEUTICS INC | 568,701 | $12.71M | 0.3% | $24.50 | — | COM | 00973Y108 |
| — | AEGLEA BIOTHERAPEUTICS INC | 1,577,296 | $12.54M | 0.3% | $7.80 | — | COM | 00773J103 |
| — | OLINK HLDG AB | 505,000 | $12.25M | 0.3% | $34.06 | — | SPONSORED ADS | 680710100 |
| RCKT | ROCKET PHARMACEUTICALS INC | 403,270 | $12.05M | 0.3% | $36.45 | -0.2% | COM | 77313F106 |
| MREO | MEREO BIOPHARMA GROUP PLC | 4,832,978 | $11.7M | 0.2% | $3.31 | — | ADS | 589492107 |
| — | APPLIED THERAPEUTICS INC | 701,680 | $11.65M | 0.2% | $31.74 | — | COM | 03828A101 |
| PRLD | PRELUDE THERAPEUTICS INC | 362,359 | $11.32M | 0.2% | $30.10 | +7.6% | COM | 74065P101 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,189,788 | $11.32M | 0.2% | $8.61 | — | SPONDS ADR | 00653A107 |
| — | TRILLIUM THERAPEUTICS INC | 628,500 | $11.04M | 0.2% | $4.28 | — | COM NEW | 89620X506 |
| — | ORION ACQUISITION CORP | 1,000,000 | $9.895M | 0.2% | $10.00 | — | UNIT 02/19/2026 | 68626A207 |
| — | INOZYME PHARMA INC | 850,015 | $9.852M | 0.2% | $25.99 | — | COM | 45790W108 |
| — | SPRUCE BIOSCIENCES INC | 1,617,601 | $9.722M | 0.2% | $24.10 | — | COM | 85209E109 |
| FOLD | AMICUS THERAPEUTICS INC | 1,012,506 | $9.669M | 0.2% | $11.49 | -11.0% | COM | 03152W109 |
| NRIX | NURIX THERAPEUTICS INC | 318,450 | $9.541M | 0.2% | $27.41 | +12.6% | COM | 67080M103 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 376,439 | $8.933M | 0.2% | $20.76 | +15.4% | COM | 23954D109 |
| XENE | XENON PHARMACEUTICALS INC | 583,100 | $8.91M | 0.2% | $14.52 | +19.6% | COM | 98420N105 |
| — | CHINOOK THERAPEUTICS INC | 688,149 | $8.781M | 0.2% | $15.84 | — | COM | 16961L106 |
| — | RENEO PHARMACEUTICALS INC | 1,143,185 | $8.517M | 0.2% | $9.31 | — | COM | 75974E103 |
| — | GAMIDA CELL LTD | 2,147,400 | $8.418M | 0.2% | $4.94 | — | SHS | M47364100 |
| — | PARATEK PHARMACEUTICALS INC | 1,665,014 | $8.092M | 0.2% | $6.16 | — | COM | 699374302 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 612,180 | $7.995M | 0.2% | $24.07 | -36.6% | COM | 76243J105 |
| — | F-STAR THERAPEUTICS INC | 1,054,232 | $7.717M | 0.2% | $8.59 | — | COM | 30315R107 |
| — | KINNATE BIOPHARMA INC | 332,986 | $7.665M | 0.2% | $39.52 | — | COM | 49705R105 |
| CGEN | COMPUGEN LTD | 1,283,790 | $7.664M | 0.2% | $6.12 | +9.4% | ORD | M25722105 |
| — | FUSION PHARMACEUTICALS INC | 948,327 | $7.511M | 0.2% | $17.41 | — | COM | 36118A100 |
| — | EARGO INC | 975,000 | $6.562M | 0.1% | $42.79 | — | COM | 270087109 |
| FATE | FATE THERAPEUTICS INC | 110,000 | $6.52M | 0.1% | $89.50 | -12.4% | COM | 31189P102 |
| STTK | SHATTUCK LABS INC | 313,499 | $6.389M | 0.1% | $32.14 | -33.4% | COM | 82024L103 |
| — | PHASEBIO PHARMACEUTICALS INC | 1,843,764 | $5.734M | 0.1% | $5.35 | — | COM | 717224109 |
| — | ATHIRA PHARMA INC | 552,252 | $5.18M | 0.1% | $18.46 | — | COM | 04746L104 |
| TBPH | THERAVANCE BIOPHARMA INC | 687,500 | $5.088M | 0.1% | $21.11 | -47.0% | COM | G8807B106 |
| DSGN | DESIGN THERAPEUTICS INC | 334,050 | $4.907M | 0.1% | $31.06 | -46.5% | COM | 25056L103 |
| EDAP | EDAP TMS S A | 760,900 | $4.855M | 0.1% | $7.09 | — | SPONSORED ADR | 268311107 |
| — | ATAI LIFE SCIENCES NV | 317,628 | $4.698M | 0.1% | $18.50 | — | SHS | N0731H103 |
| GRTX | GALERA THERAPEUTICS INC | 568,252 | $4.603M | 0.1% | $12.01 | -28.6% | COM | 36338D108 |
| — | TEMPEST THERAPEUTICS INC | 310,161 | $4.488M | 0.1% | $11.18 | — | COM | 87978U108 |
| — | ESSA PHARMA INC | 508,044 | $4.064M | 0.1% | $29.05 | — | COM NEW | 29668H708 |
| — | ACELRX PHARMACEUTICALS INC | 3,819,402 | $3.896M | 0.1% | $1.42 | — | COM | 00444T100 |
| INNV | INNOVAGE HLDG CORP | 525,000 | $3.47M | 0.1% | $23.81 | -35.0% | COM | 45784A104 |
| — | IMARA INC | 829,102 | $3.383M | 0.1% | $4.08 | — | COM | 45249V107 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $3.276M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | BCLS ACQUISITION CORP | 309,000 | $3.078M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | ATRECA INC | 459,830 | $2.865M | 0.1% | $13.90 | — | CL A COM | 04965G109 |
| NUVB | NUVATION BIO INC | 236,609 | $2.352M | 0.0% | $11.18 | -18.9% | COM CL A | 67080N101 |
| — | POSEIDA THERAPEUTICS INC | 289,754 | $2.112M | 0.0% | $8.87 | — | COM | 73730P108 |
| — | FS DEVELOPMENT CORP II | 209,332 | $2.083M | 0.0% | $9.96 | — | COM CL A | 30318F100 |
| — | EUCRATES BIOMEDICAL ACQU COR | 206,000 | $2.05M | 0.0% | $10.66 | — | UNIT 10/23/2027 | G3141W114 |
| — | TURMERIC ACQUISITION CORP | 206,000 | $2.046M | 0.0% | $10.27 | — | UNIT 10/08/2025 | G9127T116 |
| — | POPULATION HEALTH INVS CO IN | 201,044 | $2.011M | 0.0% | $10.45 | — | UNIT 99/99/9999 | G71716123 |
| — | JIYA ACQUISITION CORP | 206,200 | $2.01M | 0.0% | $10.30 | — | COM CL A | 47760M102 |
| MLTX | HELIX ACQUISITION CORP | 154,500 | $1.537M | 0.0% | $11.37 | — | COM CL A | G4444C102 |
| — | THERAVANCE BIOPHARMA INC | 1,500,000 | $1.391M | 0.0% | $1.14 | — | NOTE 3.250%11/0 | 88339KAA0 |
| — | RADIUS HEALTH INC | 1,500,000 | $1.37M | 0.0% | $1.01 | — | NOTE 3.000% 9/0 | 750469AA6 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.336M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | PACIRA BIOSCIENCES INC | 1,000,000 | $1.038M | 0.0% | $0.91 | — | NOTE 2.375% 4/0 | 695127AD2 |
| APLS | APELLIS PHARMACEUTICALS INC | 26,458 | $872K | 0.0% | $56.19 | 0.0% | COM | 03753U106 |
| — | NEVRO CORP | 500,000 | $675K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NUVATION BIO INC | 134,028 | $343K | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |