Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $4.328B (98.6% shares, 1.4% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| AGL | AGILON HEALTH INC | 7,495,000 | $202M | 4.7% | $34.43 | -29.3% | COM | 00857U107 |
| HUM | HUMANA INC | 349,000 | $162M | 3.7% | $348.05 | +22.1% | COM | 444859102 |
| ALGN | ALIGN TECHNOLOGY INC | 200,000 | $131M | 3.0% | $304.27 | +111.3% | COM | 016255101 |
| ISRG | INTUITIVE SURGICAL INC | 360,000 | $129M | 3.0% | $264.69 | +30.0% | COM NEW | 46120E602 |
| PODD | INSULET CORP | 463,750 | $123M | 2.9% | $169.26 | +71.4% | COM | 45784P101 |
| UNH | UNITEDHEALTH GROUP INC | 240,000 | $121M | 2.8% | $189.39 | +122.9% | COM | 91324P102 |
| IDXX | IDEXX LABS INC | 180,000 | $119M | 2.7% | $292.33 | +114.7% | COM | 45168D104 |
| HCA | HCA HEALTHCARE INC | 450,000 | $116M | 2.7% | $96.26 | +145.2% | COM | 40412C101 |
| ARGX | ARGENX SE | 315,000 | $110M | 2.5% | $135.42 | — | SPONSORED ADR | 04016X101 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,105,000 | $94.11M | 2.2% | $74.69 | +23.2% | COM | 64125C109 |
| — | BLUEPRINT MEDICINES CORP | 859,755 | $92.09M | 2.1% | $73.05 | — | COM | 09627Y109 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,646,625 | $87M | 2.0% | $42.81 | -6.0% | COM | 00847X104 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,471,555 | $84.63M | 2.0% | $42.22 | — | ADS | 45258D105 |
| — | HORIZON THERAPEUTICS PUB L | 746,000 | $80.39M | 1.9% | $82.74 | — | SHS | G46188101 |
| EW | EDWARDS LIFESCIENCES CORP | 582,000 | $75.4M | 1.7% | $59.31 | +96.7% | COM | 28176E108 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 883,921 | $74.33M | 1.7% | $71.86 | +13.2% | COM | 90400D108 |
| ZLAB | ZAI LAB LTD | 1,180,700 | $74.21M | 1.7% | $62.03 | — | ADR | 98887Q104 |
| BAX | BAXTER INTL INC | 733,803 | $62.99M | 1.5% | $72.19 | +1.4% | COM | 071813109 |
| NVAX | NOVAVAX INC | 425,000 | $60.8M | 1.4% | $40.40 | +325.3% | COM NEW | 670002401 |
| — | MIRATI THERAPEUTICS INC | 410,415 | $60.2M | 1.4% | $92.37 | — | COM | 60468T105 |
| PCRX | PACIRA BIOSCIENCES INC | 1,000,000 | $60.17M | 1.4% | $48.35 | +14.0% | COM | 695127100 |
| — | NEVRO CORP | 714,000 | $57.88M | 1.3% | $101.78 | — | COM | 64157F103 |
| EVH | EVOLENT HEALTH INC | 2,038,000 | $56.39M | 1.3% | $20.35 | +41.0% | CL A | 30050B101 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 332,500 | $56.38M | 1.3% | $95.74 | +94.1% | COM | 02043Q107 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,861,347 | $56.14M | 1.3% | $10.79 | +40.5% | COM | 00461U105 |
| — | KARUNA THERAPEUTICS INC | 426,843 | $55.92M | 1.3% | $74.07 | — | COM | 48576A100 |
| FRPT | FRESHPET INC | 580,000 | $55.26M | 1.3% | $60.18 | +106.1% | COM | 358039105 |
| ASND | ASCENDIS PHARMA A/S | 400,000 | $53.81M | 1.2% | $83.68 | — | SPONSORED ADR | 04351P101 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,648,435 | $53.44M | 1.2% | $21.68 | — | COM | 15678U128 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 433,000 | $50.96M | 1.2% | $55.70 | +64.7% | COM | 450056106 |
| KYMR | KYMERA THERAPEUTICS INC | 742,065 | $47.11M | 1.1% | $34.80 | +67.4% | COM | 501575104 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 748,500 | $45.43M | 1.0% | $45.81 | +30.2% | COM | 00404A109 |
| EXAS | EXACT SCIENCES CORP | 570,000 | $44.36M | 1.0% | $56.53 | +56.1% | COM | 30063P105 |
| — | INVITAE CORP | 2,800,243 | $42.76M | 1.0% | $23.39 | — | COM | 46185L103 |
| PEN | PENUMBRA INC | 148,500 | $42.67M | 1.0% | $55.16 | +379.3% | COM | 70975L107 |
| — | SHOCKWAVE MED INC | 222,500 | $39.68M | 0.9% | $51.72 | — | COM | 82489T104 |
| — | SEAGEN INC | 256,000 | $39.58M | 0.9% | $174.66 | — | COM | 81181C104 |
| SRPT | SAREPTA THERAPEUTICS INC | 424,000 | $38.18M | 0.9% | $60.98 | +40.2% | COM | 803607100 |
| ARVN | ARVINAS INC | 457,200 | $37.55M | 0.9% | $32.84 | +147.8% | COM | 04335A105 |
| — | CYTOKINETICS INC | 8,000,000 | $35.66M | 0.8% | $1.32 | — | NOTE 4.000%11/1 | 23282WAA8 |
| WRBY | WARBY PARKER INC | 724,000 | $33.71M | 0.8% | $53.59 | -2.9% | CL A COM | 93403J106 |
| HCAT | HEALTH CATALYST INC | 850,200 | $33.69M | 0.8% | $35.51 | +28.3% | COM | 42225T107 |
| — | VERVE THERAPEUTICS INC | 902,926 | $33.29M | 0.8% | $60.25 | — | COM | 92539P101 |
| — | COVETRUS INC | 1,661,700 | $33.18M | 0.8% | $21.18 | — | COM | 22304C100 |
| EHC | ENCOMPASS HEALTH CORP | 502,500 | $32.79M | 0.8% | $45.98 | +7.5% | COM | 29261A100 |
| PHR | PHREESIA INC | 770,000 | $32.08M | 0.7% | $31.31 | +89.7% | COM | 71944F106 |
| PRTA | PROTHENA CORP PLC | 647,730 | $32M | 0.7% | $11.75 | +372.0% | SHS | G72800108 |
| — | ACCOLADE INC | 1,197,000 | $31.55M | 0.7% | $38.59 | — | COM | 00437E102 |
| DXCM | DEXCOM INC | 56,750 | $30.47M | 0.7% | $104.55 | +37.4% | COM | 252131107 |
| TVTX | TRAVERE THERAPEUTICS INC | 951,650 | $29.54M | 0.7% | $24.60 | +14.5% | COM | 89422G107 |
| — | ABCAM PLC | 1,252,500 | $29.5M | 0.7% | $21.34 | — | ADS | 000380204 |
| CNMD | CONMED CORP | 202,500 | $28.71M | 0.7% | $114.93 | +18.7% | COM | 207410101 |
| — | GRAPHITE BIO INC | 2,078,910 | $25.84M | 0.6% | $30.73 | — | COM | 38870X104 |
| — | SIERRA ONCOLOGY INC | 1,184,793 | $25.76M | 0.6% | $17.77 | — | COM NEW | 82640U404 |
| — | INTERSECT ENT INC | 940,000 | $25.67M | 0.6% | $22.46 | — | COM | 46071F103 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,538,814 | $24.54M | 0.6% | $12.91 | +20.5% | COM | 604749101 |
| — | PROMETHEUS BIOSCIENCES INC | 618,407 | $24.45M | 0.6% | $18.88 | — | COM | 74349U108 |
| XENE | XENON PHARMACEUTICALS INC | 771,367 | $24.1M | 0.6% | $18.27 | +63.5% | COM | 98420N105 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 264,000 | $23.32M | 0.5% | $85.70 | -3.7% | COM | 09061G101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 269,400 | $22.83M | 0.5% | $42.50 | +93.3% | COM | 558868105 |
| LUNG | PULMONX CORP | 700,000 | $22.45M | 0.5% | $48.60 | -24.9% | COM | 745848101 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,576,894 | $22.19M | 0.5% | $7.49 | — | COM NEW | 268158201 |
| WST | WEST PHARMACEUTICAL SVSC INC | 45,500 | $21.34M | 0.5% | $219.29 | +94.2% | COM | 955306105 |
| — | MERSANA THERAPEUTICS INC | 3,248,950 | $20.21M | 0.5% | $15.28 | — | COM | 59045L106 |
| GH | GUARDANT HEALTH INC | 200,000 | $20M | 0.5% | $42.73 | +142.1% | COM | 40131M109 |
| XLO | XILIO THERAPEUTICS INC | 1,191,094 | $19.06M | 0.4% | $17.03 | 0.0% | COM | 98422T100 |
| LFST | LIFESTANCE HEALTH GROUP INC | 2,000,000 | $19.04M | 0.4% | $23.27 | -54.4% | COM | 53228F101 |
| LEGN | LEGEND BIOTECH CORP | 403,584 | $18.81M | 0.4% | $39.93 | — | SPONSORED ADS | 52490G102 |
| ANAB | ANAPTYSBIO INC | 538,700 | $18.72M | 0.4% | $28.24 | +12.3% | COM | 032724106 |
| RLAY | RELAY THERAPEUTICS INC | 597,767 | $18.36M | 0.4% | $34.87 | -9.4% | COM | 75943R102 |
| IMRX | IMMUNEERING CORP | 1,089,816 | $17.62M | 0.4% | $26.87 | -9.4% | CLASS A COM | 45254E107 |
| AURA | AURA BIOSCIENCES INC | 1,008,114 | $17.12M | 0.4% | $17.87 | 0.0% | COM | 05153U107 |
| CMPX | COMPASS THERAPEUTICS INC | 5,328,088 | $16.89M | 0.4% | $3.29 | 0.0% | COM | 20454B104 |
| — | ICOSAVAX INC | 735,504 | $16.83M | 0.4% | $29.59 | — | COM | 45114M109 |
| SPRO | SPERO THERAPEUTICS INC | 945,313 | $15.13M | 0.3% | $11.82 | +34.4% | COM | 84833T103 |
| — | GOSSAMER BIO INC | 15,373,000 | $15.07M | 0.3% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | AMARIN CORP PLC | 4,419,700 | $14.89M | 0.3% | $4.90 | — | SPONS ADR NEW | 023111206 |
| — | AMRYT PHARMA PLC | 1,305,825 | $14.1M | 0.3% | $12.05 | — | SPONSORED ADS | 03217L106 |
| MGNX | MACROGENICS INC | 857,205 | $13.76M | 0.3% | $22.34 | -15.7% | COM | 556099109 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 725,000 | $13.54M | 0.3% | $15.97 | +22.1% | COM | 19459J104 |
| NVCR | NOVOCURE LTD | 175,000 | $13.14M | 0.3% | $37.58 | +167.1% | ORD SHS | G6674U108 |
| WHWK | AADI BIOSCIENCE INC | 538,835 | $13.01M | 0.3% | $30.48 | -17.6% | COM | 00032Q104 |
| — | RIGEL PHARMACEUTICALS INC | 4,860,200 | $12.88M | 0.3% | $2.87 | — | COM NEW | 766559603 |
| — | AKERO THERAPEUTICS INC | 587,101 | $12.42M | 0.3% | $24.39 | — | COM | 00973Y108 |
| — | CHINOOK THERAPEUTICS INC | 720,349 | $11.75M | 0.3% | $15.86 | — | COM | 16961L106 |
| FOLD | AMICUS THERAPEUTICS INC | 1,012,506 | $11.69M | 0.3% | $11.49 | -3.0% | COM | 03152W109 |
| — | LEAP THERAPEUTICS INC | 3,520,570 | $11.41M | 0.3% | $4.01 | — | COM | 52187K101 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 1,571,918 | $10.63M | 0.2% | $16.64 | -33.9% | COM | 00509G209 |
| AUPH | AURINIA PHARMACEUTICALS INC | 457,173 | $10.46M | 0.2% | $14.49 | +63.6% | COM | 05156V102 |
| CGEM | CULLINAN ONCOLOGY INC | 646,078 | $9.969M | 0.2% | $40.60 | -50.9% | COM | 230031106 |
| — | ORION ACQUISITION CORP | 1,000,000 | $9.85M | 0.2% | $10.00 | — | UNIT 02/19/2026 | 68626A207 |
| — | RENEO PHARMACEUTICALS INC | 1,143,185 | $9.774M | 0.2% | $9.31 | — | COM | 75974E103 |
| — | EPIZYME INC | 3,807,662 | $9.519M | 0.2% | $11.67 | — | COM | 29428V104 |
| — | OLINK HLDG AB | 515,000 | $9.373M | 0.2% | $33.75 | — | SPONSORED ADS | 680710100 |
| NRIX | NURIX THERAPEUTICS INC | 321,050 | $9.294M | 0.2% | $27.41 | +10.6% | COM | 67080M103 |
| MREO | MEREO BIOPHARMA GROUP PLC | 5,585,621 | $8.937M | 0.2% | $3.08 | — | ADS | 589492107 |
| BMEA | BIOMEA FUSION INC | 1,165,582 | $8.684M | 0.2% | $17.65 | -40.1% | COM | 09077A106 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,215,588 | $8.308M | 0.2% | $8.55 | — | SPONDS ADR | 00653A107 |
| — | VINCERX PHARMA INC | 809,195 | $8.246M | 0.2% | $16.10 | — | COM NEW | 92731L106 |
| FULC | FULCRUM THERAPEUTICS INC | 456,990 | $8.084M | 0.2% | $18.95 | +4.5% | COM | 359616109 |
| NKTX | NKARTA INC | 507,248 | $7.786M | 0.2% | $29.49 | -41.8% | COM | 65487U108 |
| — | PARATEK PHARMACEUTICALS INC | 1,697,105 | $7.62M | 0.2% | $6.13 | — | COM | 699374302 |
| — | AEGLEA BIOTHERAPEUTICS INC | 1,577,296 | $7.492M | 0.2% | $7.80 | — | COM | 00773J103 |
| — | ESSA PHARMA INC | 511,044 | $7.257M | 0.2% | $29.05 | — | COM NEW | 29668H708 |
| — | SPRUCE BIOSCIENCES INC | 1,622,689 | $7.237M | 0.2% | $24.10 | — | COM | 85209E109 |
| — | ATHIRA PHARMA INC | 552,252 | $7.196M | 0.2% | $18.46 | — | COM | 04746L104 |
| DSGN | DESIGN THERAPEUTICS INC | 335,247 | $7.178M | 0.2% | $31.06 | -44.7% | COM | 25056L103 |
| — | PHASEBIO PHARMACEUTICALS INC | 2,581,299 | $6.737M | 0.2% | $4.57 | — | COM | 717224109 |
| FATE | FATE THERAPEUTICS INC | 110,000 | $6.436M | 0.1% | $89.50 | -36.7% | COM | 31189P102 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 381,939 | $6.436M | 0.1% | $20.76 | -1.0% | COM | 23954D109 |
| — | APPLIED THERAPEUTICS INC | 701,680 | $6.28M | 0.1% | $31.74 | — | COM | 03828A101 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 627,180 | $6.259M | 0.1% | $23.76 | -52.7% | COM | 76243J105 |
| — | KINNATE BIOPHARMA INC | 339,846 | $6.022M | 0.1% | $39.08 | — | COM | 49705R105 |
| — | INOZYME PHARMA INC | 868,466 | $5.923M | 0.1% | $25.58 | — | COM | 45790W108 |
| CGEN | COMPUGEN LTD | 1,289,990 | $5.547M | 0.1% | $6.12 | -11.7% | ORD | M25722105 |
| — | THESEUS PHARMACEUTICALS INC | 437,329 | $5.545M | 0.1% | $12.68 | — | COM | 88369M101 |
| — | GAMIDA CELL LTD | 2,154,300 | $5.472M | 0.1% | $4.94 | — | SHS | M47364100 |
| PRLD | PRELUDE THERAPEUTICS INC | 368,959 | $4.594M | 0.1% | $29.85 | -45.5% | COM | 74065P101 |
| EDAP | EDAP TMS S A | 760,900 | $4.558M | 0.1% | $7.09 | — | SPONSORED ADR | 268311107 |
| — | TEMPEST THERAPEUTICS INC | 823,654 | $4.349M | 0.1% | $7.50 | — | COM | 87978U108 |
| — | FUSION PHARMACEUTICALS INC | 948,327 | $3.955M | 0.1% | $17.41 | — | COM | 36118A100 |
| — | F-STAR THERAPEUTICS INC | 751,889 | $3.774M | 0.1% | $8.59 | — | COM | 30315R107 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $3.589M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | ACELRX PHARMACEUTICALS INC | 6,325,902 | $3.544M | 0.1% | $1.08 | — | COM | 00444T100 |
| — | BCLS ACQUISITION CORP | 309,000 | $3.028M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| STTK | SHATTUCK LABS INC | 313,499 | $2.668M | 0.1% | $32.14 | -57.1% | COM | 82024L103 |
| — | JIYA ACQUISITION CORP | 206,200 | $2.015M | 0.0% | $10.30 | — | COM CL A | 47760M102 |
| — | POSEIDA THERAPEUTICS INC | 289,754 | $1.973M | 0.0% | $8.87 | — | COM | 73730P108 |
| — | IMARA INC | 842,302 | $1.895M | 0.0% | $4.05 | — | COM | 45249V107 |
| — | RADIUS HEALTH INC | 1,500,000 | $1.459M | 0.0% | $1.01 | — | NOTE 3.000% 9/0 | 750469AA6 |
| — | THERAVANCE BIOPHARMA INC | 1,500,000 | $1.456M | 0.0% | $1.14 | — | NOTE 3.250%11/0 | 88339KAA0 |
| — | ATRECA INC | 462,530 | $1.401M | 0.0% | $13.90 | — | CL A COM | 04965G109 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.257M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | PACIRA BIOSCIENCES INC | 1,000,000 | $1.029M | 0.0% | $0.91 | — | NOTE 2.375% 4/0 | 695127AD2 |
| — | NEVRO CORP | 500,000 | $556K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NUVATION BIO INC | 134,028 | $253K | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |