Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q4 2014 (← Previous) (Next →)

Filing Date: Feb 17, 2015

Total Value: $1.704B (100.0% shares, 0.0% debt)

Holdings (46)

UTHR UNITED THERAPEUTICS CORP DEL 10.7%
Value $182M Shares 1,403,128 Share Price $129.49 Est. Cost/Share $75.71 Unrealized @ Report Date +70.2%
— AUXILIUM PHARMACEUTICALS INC 9.9%
Value $169M Shares 4,915,931 Share Price $34.38 Est. Cost/Share $17.66 Unrealized @ Report Date —
— CUBIST PHARMACEUTICALS INC 7.7%
Value $131M Shares 1,303,668 Share Price $100.65 Est. Cost/Share $59.40 Unrealized @ Report Date —
— CLOVIS ONCOLOGY INC 6.9%
Value $118M Shares 2,102,857 Share Price $56.00 Est. Cost/Share $47.24 Unrealized @ Report Date —
BMRN BIOMARIN PHARMACEUTICAL INC 6.9%
Value $118M Shares 1,302,197 Share Price $90.40 * Est. Cost/Share $64.35 Unrealized @ Report Date +29.2%
— ABIOMED INC 5.5%
Value $93.63M Shares 2,460,124 Share Price $38.06 Est. Cost/Share $21.84 Unrealized @ Report Date —
— CYBERONICS INC 5.3%
Value $89.54M Shares 1,608,101 Share Price $55.68 Est. Cost/Share $52.15 Unrealized @ Report Date —
— AMAG PHARMACEUTICALS INC 5.0%
Value $84.99M Shares 1,994,200 Share Price $42.62 Est. Cost/Share $26.16 Unrealized @ Report Date —
— ANACOR PHARMACEUTICALS INC 4.8%
Value $81.33M Shares 2,521,822 Share Price $32.25 Est. Cost/Share $13.71 Unrealized @ Report Date —
INSM INSMED INC 4.2%
Value $71.56M Shares 4,625,648 Share Price $15.47 * Est. Cost/Share $14.64 Unrealized @ Report Date -3.1%
— WRIGHT MED GROUP INC 3.2%
Value $54.81M Shares 2,039,751 Share Price $26.87 Est. Cost/Share $28.27 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 3.2%
Value $54.23M Shares 3,786,908 Share Price $14.32 * Est. Cost/Share $8.33 Unrealized @ Report Date +42.1%
— NPS PHARMACEUTICALS INC 2.5%
Value $42.58M Shares 1,190,263 Share Price $35.77 Est. Cost/Share $27.84 Unrealized @ Report Date —
— KYTHERA BIOPHARMACEUTICALS I 2.3%
Value $38.91M Shares 1,121,884 Share Price $34.68 Est. Cost/Share $37.65 Unrealized @ Report Date —
— SEQUENOM INC 2.2%
Value $36.73M Shares 9,925,742 Share Price $3.70 Est. Cost/Share $3.91 Unrealized @ Report Date —
— CELLADON CORP 1.6%
Value $27.42M Shares 1,403,800 Share Price $19.53 Est. Cost/Share $11.92 Unrealized @ Report Date —
— CELGENE CORP 1.4%
Value $24.11M Shares 215,500 Share Price $111.86 Est. Cost/Share $92.73 Unrealized @ Report Date —
STAA STAAR SURGICAL CO 1.4%
Value $23.96M Shares 2,629,622 Share Price $9.11 * Est. Cost/Share $8.11 Unrealized @ Report Date +19.3%
GILD GILEAD SCIENCES INC 1.3%
Value $22.11M Shares 234,600 Share Price $94.26 * Est. Cost/Share $59.95 Unrealized @ Report Date +19.9%
— SHIRE PLC 1.1%
Value $18.19M Shares 85,600 Share Price $212.54 Est. Cost/Share $227.79 Unrealized @ Report Date —
— MOMENTA PHARMACEUTICALS INC 1.0%
Value $17.52M Shares 1,455,176 Share Price $12.04 Est. Cost/Share $14.44 Unrealized @ Report Date —
— ALIMERA SCIENCES INC 1.0%
Value $16.7M Shares 3,013,793 Share Price $5.54 Est. Cost/Share $4.88 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.0%
Value $16.28M Shares 1,956,376 Share Price $8.32 * Est. Cost/Share $3.07 Unrealized @ Report Date +123.3%
— MEDIVATION INC 0.9%
Value $16.07M Shares 161,300 Share Price $99.61 Est. Cost/Share $82.41 Unrealized @ Report Date —
— ARIAD PHARMACEUTICALS INC 0.9%
Value $15.33M Shares 2,231,717 Share Price $6.87 Est. Cost/Share $6.82 Unrealized @ Report Date —
PRTA PROTHENA CORP PLC 0.8%
Value $14.35M Shares 691,218 Share Price $20.76 Est. Cost/Share $22.18 Unrealized @ Report Date -5.9%
— ACELRX PHARMACEUTICALS INC 0.8%
Value $14.32M Shares 2,128,539 Share Price $6.73 Est. Cost/Share $5.78 Unrealized @ Report Date —
— INTUITIVE SURGICAL INC 0.8%
Value $13.78M Shares 26,050 Share Price $528.94 Est. Cost/Share $433.70 Unrealized @ Report Date —
ALGN ALIGN TECHNOLOGY INC 0.8%
Value $13.1M Shares 234,300 Share Price $55.91 * Est. Cost/Share $52.61 Unrealized @ Report Date +0.5%
— RIGEL PHARMACEUTICALS INC 0.7%
Value $11.75M Shares 5,176,319 Share Price $2.27 Est. Cost/Share $3.43 Unrealized @ Report Date —
— OREXIGEN THERAPEUTICS INC 0.7%
Value $11.7M Shares 1,931,324 Share Price $6.06 Est. Cost/Share $6.46 Unrealized @ Report Date —
— ZELTIQ AESTHETICS INC 0.6%
Value $11.01M Shares 394,486 Share Price $27.91 Est. Cost/Share $24.11 Unrealized @ Report Date —
EXAS EXACT SCIENCES CORP 0.6%
Value $10.74M Shares 391,276 Share Price $27.44 * Est. Cost/Share $12.83 Unrealized @ Report Date +89.6%
— SALIX PHARMACEUTICALS INC 0.5%
Value $8.816M Shares 76,700 Share Price $114.94 Est. Cost/Share $114.94 Unrealized @ Report Date —
— THORATEC CORP 0.5%
Value $8.727M Shares 268,861 Share Price $32.46 Est. Cost/Share $32.46 Unrealized @ Report Date —
— QLT INC 0.4%
Value $6.95M Shares 1,733,208 Share Price $4.01 Est. Cost/Share $4.40 Unrealized @ Report Date —
— HISTOGENICS CORP 0.3%
Value $5M Shares 454,545 Share Price $11.00 Est. Cost/Share $11.00 Unrealized @ Report Date —
— XOMA CORP DEL 0.2%
Value $2.852M Shares 794,500 Share Price $3.59 Est. Cost/Share $4.07 Unrealized @ Report Date —
— BIOSPECIFICS TECHNOLOGIES CO 0.1%
Value $1.948M Shares 50,436 Share Price $38.62 Est. Cost/Share $34.45 Unrealized @ Report Date —
— HYPERION THERAPEUTICS INC 0.1%
Value $1.505M Shares 62,700 Share Price $24.00 Est. Cost/Share $22.00 Unrealized @ Report Date —
— INTREXON CORP 0.1%
Value $1.203M Shares 43,700 Share Price $27.53 Est. Cost/Share $27.53 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.1%
Value $991K Shares 123,686 Share Price $8.01 * Est. Cost/Share $6.71 Unrealized @ Report Date -36.1%
— AVEO PHARMACEUTICALS INC 0.0%
Value $562K Shares 669,449 Share Price $0.84 Est. Cost/Share $2.50 Unrealized @ Report Date —
— NXSTAGE MEDICAL INC 0.0%
Value $362K Shares 20,200 Share Price $17.92 Est. Cost/Share $17.92 Unrealized @ Report Date —
— MALLINCKRODT PUB LTD CO 0.0%
Value $355K Shares 3,588 Share Price $98.94 Est. Cost/Share $90.02 Unrealized @ Report Date —
— SOPHIRIS BIO INC 0.0%
Value $103K Shares 191,600 Share Price $0.54 Est. Cost/Share $3.88 Unrealized @ Report Date —