Palo Alto Investors LP Long-Term Concentrated

CIK: 0001306923 · Show all filings

Period: Q4 2014 (← Previous) (Next →)

Filing Date: Feb 17, 2015

Total Value ($000): $1,703,520 (100.0% shares, 0.0% debt)

Holdings (46)

UTHR UNITED THERAPEUTICS CORP DEL 10.7%
Value ($000) $181,691 Shares 1,403,128 Est. Cost $75.71 Unrealized +70.2%
— AUXILIUM PHARMACEUTICALS INC 9.9%
Value ($000) $169,034 Shares 4,915,931 Est. Cost $17.66 Unrealized —
— CUBIST PHARMACEUTICALS INC 7.7%
Value ($000) $131,214 Shares 1,303,668 Est. Cost $59.40 Unrealized —
— CLOVIS ONCOLOGY INC 6.9%
Value ($000) $117,760 Shares 2,102,857 Est. Cost $47.24 Unrealized —
BMRN BIOMARIN PHARMACEUTICAL INC 6.9%
Value ($000) $117,719 Shares 1,302,197 Est. Cost $64.35 Unrealized +29.2%
— ABIOMED INC 5.5%
Value ($000) $93,632 Shares 2,460,124 Est. Cost $21.84 Unrealized —
— CYBERONICS INC 5.3%
Value ($000) $89,539 Shares 1,608,101 Est. Cost $52.15 Unrealized —
— AMAG PHARMACEUTICALS INC 5.0%
Value ($000) $84,993 Shares 1,994,200 Est. Cost $26.16 Unrealized —
— ANACOR PHARMACEUTICALS INC 4.8%
Value ($000) $81,329 Shares 2,521,822 Est. Cost $13.71 Unrealized —
INSM INSMED INC 4.2%
Value ($000) $71,559 Shares 4,625,648 Est. Cost $14.64 Unrealized -3.1%
— WRIGHT MED GROUP INC 3.2%
Value ($000) $54,808 Shares 2,039,751 Est. Cost $28.27 Unrealized —
VNDA VANDA PHARMACEUTICALS INC 3.2%
Value ($000) $54,229 Shares 3,786,908 Est. Cost $8.33 Unrealized +42.1%
— NPS PHARMACEUTICALS INC 2.5%
Value ($000) $42,576 Shares 1,190,263 Est. Cost $27.84 Unrealized —
— KYTHERA BIOPHARMACEUTICALS I 2.3%
Value ($000) $38,907 Shares 1,121,884 Est. Cost $37.65 Unrealized —
— SEQUENOM INC 2.2%
Value ($000) $36,725 Shares 9,925,742 Est. Cost $3.91 Unrealized —
— CELLADON CORP 1.6%
Value ($000) $27,416 Shares 1,403,800 Est. Cost $11.92 Unrealized —
— CELGENE CORP 1.4%
Value ($000) $24,106 Shares 215,500 Est. Cost $92.73 Unrealized —
STAA STAAR SURGICAL CO 1.4%
Value ($000) $23,956 Shares 2,629,622 Est. Cost $8.11 Unrealized +19.3%
GILD GILEAD SCIENCES INC 1.3%
Value ($000) $22,113 Shares 234,600 Est. Cost $59.95 Unrealized +19.9%
— SHIRE PLC 1.1%
Value ($000) $18,193 Shares 85,600 Est. Cost $227.79 Unrealized —
— MOMENTA PHARMACEUTICALS INC 1.0%
Value ($000) $17,520 Shares 1,455,176 Est. Cost $14.44 Unrealized —
— ALIMERA SCIENCES INC 1.0%
Value ($000) $16,696 Shares 3,013,793 Est. Cost $4.88 Unrealized —
FOLD AMICUS THERAPEUTICS INC 1.0%
Value ($000) $16,277 Shares 1,956,376 Est. Cost $3.07 Unrealized +123.3%
— MEDIVATION INC 0.9%
Value ($000) $16,067 Shares 161,300 Est. Cost $82.41 Unrealized —
— ARIAD PHARMACEUTICALS INC 0.9%
Value ($000) $15,332 Shares 2,231,717 Est. Cost $6.82 Unrealized —
PRTA PROTHENA CORP PLC 0.8%
Value ($000) $14,350 Shares 691,218 Est. Cost $22.18 Unrealized -5.9%
— ACELRX PHARMACEUTICALS INC 0.8%
Value ($000) $14,325 Shares 2,128,539 Est. Cost $5.78 Unrealized —
— INTUITIVE SURGICAL INC 0.8%
Value ($000) $13,779 Shares 26,050 Est. Cost $433.70 Unrealized —
ALGN ALIGN TECHNOLOGY INC 0.8%
Value ($000) $13,100 Shares 234,300 Est. Cost $52.61 Unrealized +0.5%
— RIGEL PHARMACEUTICALS INC 0.7%
Value ($000) $11,750 Shares 5,176,319 Est. Cost $3.43 Unrealized —
— OREXIGEN THERAPEUTICS INC 0.7%
Value ($000) $11,704 Shares 1,931,324 Est. Cost $6.46 Unrealized —
— ZELTIQ AESTHETICS INC 0.6%
Value ($000) $11,010 Shares 394,486 Est. Cost $24.11 Unrealized —
EXAS EXACT SCIENCES CORP 0.6%
Value ($000) $10,737 Shares 391,276 Est. Cost $12.83 Unrealized +89.6%
— SALIX PHARMACEUTICALS INC 0.5%
Value ($000) $8,816 Shares 76,700 Est. Cost $114.94 Unrealized —
— THORATEC CORP 0.5%
Value ($000) $8,727 Shares 268,861 Est. Cost $32.46 Unrealized —
— QLT INC 0.4%
Value ($000) $6,950 Shares 1,733,208 Est. Cost $4.40 Unrealized —
— HISTOGENICS CORP 0.3%
Value ($000) $5,000 Shares 454,545 Est. Cost $11.00 Unrealized —
— XOMA CORP DEL 0.2%
Value ($000) $2,852 Shares 794,500 Est. Cost $4.07 Unrealized —
— BIOSPECIFICS TECHNOLOGIES CO 0.1%
Value ($000) $1,948 Shares 50,436 Est. Cost $34.45 Unrealized —
— HYPERION THERAPEUTICS INC 0.1%
Value ($000) $1,505 Shares 62,700 Est. Cost $22.00 Unrealized —
— INTREXON CORP 0.1%
Value ($000) $1,203 Shares 43,700 Est. Cost $27.53 Unrealized —
CYTK CYTOKINETICS INC 0.1%
Value ($000) $991 Shares 123,686 Est. Cost $6.71 Unrealized -36.1%
— AVEO PHARMACEUTICALS INC 0.0%
Value ($000) $562 Shares 669,449 Est. Cost $2.50 Unrealized —
— NXSTAGE MEDICAL INC 0.0%
Value ($000) $362 Shares 20,200 Est. Cost $17.92 Unrealized —
— MALLINCKRODT PUB LTD CO 0.0%
Value ($000) $355 Shares 3,588 Est. Cost $90.02 Unrealized —
— SOPHIRIS BIO INC 0.0%
Value ($000) $103 Shares 191,600 Est. Cost $3.88 Unrealized —