PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value: $1.301B (98.8% shares, 1.2% debt)

Holdings (72)

LLY ELI LILLY & CO 13.2%
Value $172M Shares 225,139 Share Price $763.00 * Est. Cost/Share $156.24 Unrealized @ Report Date +375.1%
THC TENET HEALTHCARE CORP 7.2%
Value $93.73M Shares 461,654 Share Price $203.04 * Est. Cost/Share $52.95 Unrealized @ Report Date +235.1%
XBI SPDR SERIES TRUST 5.5%
Value $71.88M Shares 717,400 Share Price $100.20 Est. Cost/Share — Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 5.0%
Value $64.41M Shares 530,332 Share Price $121.45 * Est. Cost/Share $54.98 Unrealized @ Report Date +104.9%
MCK MCKESSON CORP 4.3%
Value $55.86M Shares 72,313 Share Price $772.54 * Est. Cost/Share $163.53 Unrealized @ Report Date +329.9%
PEN PENUMBRA INC 3.8%
Value $49.42M Shares 195,085 Share Price $253.32 Est. Cost/Share $201.49 Unrealized @ Report Date +25.2%
UTHR UNITED THERAPEUTICS CORP DEL 3.1%
Value $40.1M Shares 95,650 Share Price $419.21 * Est. Cost/Share $322.06 Unrealized @ Report Date +4.4%
ISRG INTUITIVE SURGICAL INC 2.7%
Value $34.62M Shares 77,403 Share Price $447.23 * Est. Cost/Share $358.21 Unrealized @ Report Date +34.0%
EW EDWARDS LIFESCIENCES CORP 2.3%
Value $29.66M Shares 381,324 Share Price $77.77 Est. Cost/Share $74.29 Unrealized @ Report Date +5.2%
ASND ASCENDIS PHARMA A/S 2.2%
Value $28.89M Shares 145,311 Share Price $198.81 Est. Cost/Share $156.94 Unrealized @ Report Date —
HUM HUMANA INC 2.2%
Value $28.62M Shares 110,000 Share Price $260.17 Est. Cost/Share $306.16 Unrealized @ Report Date -14.7%
HCA HCA HEALTHCARE INC 2.2%
Value $28.03M Shares 65,773 Share Price $426.20 * Est. Cost/Share $229.48 Unrealized @ Report Date +68.4%
CVS CVS HEALTH CORP 2.0%
Value $26.14M Shares 346,679 Share Price $75.39 * Est. Cost/Share $60.15 Unrealized @ Report Date +12.8%
COR CENCORA INC 1.9%
Value $25.16M Shares 80,493 Share Price $312.53 * Est. Cost/Share $289.07 Unrealized @ Report Date +1.5%
OM OUTSET MED INC 1.9%
Value $24.43M Shares 1,729,921 Share Price $14.12 * Est. Cost/Share $12.06 Unrealized @ Report Date +29.3%
UHS UNIVERSAL HLTH SVCS INC 1.8%
Value $23.77M Shares 116,260 Share Price $204.44 * Est. Cost/Share $179.65 Unrealized @ Report Date 0.0%
ICLR ICON PLC 1.8%
Value $23.39M Shares 133,683 Share Price $175.00 * Est. Cost/Share $174.03 Unrealized @ Report Date -3.8%
CNC CENTENE CORP DEL 1.6%
Value $20.49M Shares 574,360 Share Price $35.68 * Est. Cost/Share $30.20 Unrealized @ Report Date 0.0%
MRK MERCK & CO INC 1.5%
Value $19.85M Shares 236,468 Share Price $83.93 * Est. Cost/Share $81.01 Unrealized @ Report Date 0.0%
ELV ELEVANCE HEALTH INC FORMERLY 1.5%
Value $19.64M Shares 60,776 Share Price $323.12 * Est. Cost/Share $308.14 Unrealized @ Report Date 0.0%
NTRA NATERA INC 1.4%
Value $18.61M Shares 115,596 Share Price $160.97 Est. Cost/Share $156.13 Unrealized @ Report Date +1.3%
ADMA ADMA BIOLOGICS INC 1.3%
Value $17.31M Shares 1,181,011 Share Price $14.66 * Est. Cost/Share $17.14 Unrealized @ Report Date 0.0%
NEO NEOGENOMICS INC 1.3%
Value $17.05M Shares 2,208,530 Share Price $7.72 * Est. Cost/Share $8.55 Unrealized @ Report Date -18.0%
BBIO BRIDGEBIO PHARMA INC 1.3%
Value $16.99M Shares 327,174 Share Price $51.94 * Est. Cost/Share $31.20 Unrealized @ Report Date +56.3%
SLNO SOLENO THERAPEUTICS INC 1.3%
Value $16.45M Shares 243,401 Share Price $67.60 * Est. Cost/Share $50.31 Unrealized @ Report Date +47.4%
CNTA CENTESSA PHARMACEUTICALS PLC 1.2%
Value $16.16M Shares 666,196 Share Price $24.25 Est. Cost/Share $18.33 Unrealized @ Report Date —
— ASCENDIS PHARMA A/S 1.2%
Value $15.7M Shares 11,515,000 Share Price $1.36 Est. Cost/Share $1.14 Unrealized @ Report Date —
OSCR OSCAR HEALTH INC 1.2%
Value $15.53M Shares 820,642 Share Price $18.93 * Est. Cost/Share $11.78 Unrealized @ Report Date +40.0%
RVMD REVOLUTION MEDICINES INC 1.2%
Value $15.46M Shares 331,069 Share Price $46.70 * Est. Cost/Share $39.15 Unrealized @ Report Date 0.0%
VERA VERA THERAPEUTICS INC 1.1%
Value $14.93M Shares 513,685 Share Price $29.06 * Est. Cost/Share $23.13 Unrealized @ Report Date 0.0%
SPY SPDR S&P 500 ETF TR 1.1%
Value $14.13M Shares 21,210 Share Price $666.18 Est. Cost/Share $627.15 Unrealized @ Report Date —
IWM ISHARES TR 1.1%
Value $13.72M Shares 56,700 Share Price $241.96 Est. Cost/Share — Unrealized @ Report Date —
— INDIVIOR PLC 1.0%
Value $13.54M Shares 561,526 Share Price $24.11 Est. Cost/Share $10.28 Unrealized @ Report Date —
VEEV VEEVA SYS INC 1.0%
Value $12.36M Shares 41,503 Share Price $297.91 * Est. Cost/Share $281.43 Unrealized @ Report Date 0.0%
— MERUS N V 0.9%
Value $12.31M Shares 130,742 Share Price $94.15 Est. Cost/Share $52.60 Unrealized @ Report Date —
BSX BOSTON SCIENTIFIC CORP 0.9%
Value $11.91M Shares 122,000 Share Price $97.63 * Est. Cost/Share $103.56 Unrealized @ Report Date 0.0%
— AKERO THERAPEUTICS INC 0.9%
Value $11.78M Shares 248,079 Share Price $47.48 Est. Cost/Share $53.36 Unrealized @ Report Date —
REGN REGENERON PHARMACEUTICALS 0.9%
Value $11.18M Shares 19,890 Share Price $562.27 Est. Cost/Share $564.28 Unrealized @ Report Date 0.0%
IRTC IRHYTHM TECHNOLOGIES INC 0.9%
Value $11.18M Shares 64,998 Share Price $171.99 * Est. Cost/Share $129.23 Unrealized @ Report Date +23.0%
CMPS COMPASS PATHWAYS PLC 0.7%
Value $9.528M Shares 1,662,836 Share Price $5.73 Est. Cost/Share $4.25 Unrealized @ Report Date —
WAT WATERS CORP 0.7%
Value $9.219M Shares 30,751 Share Price $299.81 Est. Cost/Share $332.10 Unrealized @ Report Date -9.1%
— VERONA PHARMA PLC 0.7%
Value $8.581M Shares 80,416 Share Price $106.71 Est. Cost/Share $94.58 Unrealized @ Report Date —
INBX INHIBRX BIOSCIENCES INC 0.6%
Value $8.071M Shares 239,644 Share Price $33.68 * Est. Cost/Share $14.21 Unrealized @ Report Date +73.2%
NBIX NEUROCRINE BIOSCIENCES INC 0.6%
Value $8.036M Shares 57,246 Share Price $140.38 * Est. Cost/Share $130.83 Unrealized @ Report Date +3.6%
TEVA TEVA PHARMACEUTICAL INDS LTD 0.6%
Value $7.208M Shares 356,818 Share Price $20.20 Est. Cost/Share $16.76 Unrealized @ Report Date —
ARQT ARCUTIS BIOTHERAPEUTICS INC 0.5%
Value $6.795M Shares 360,460 Share Price $18.85 * Est. Cost/Share $14.02 Unrealized @ Report Date +12.5%
CGON CG ONCOLOGY INC 0.5%
Value $6.359M Shares 157,874 Share Price $40.28 * Est. Cost/Share $29.07 Unrealized @ Report Date 0.0%
AMLX AMYLYX PHARMACEUTICALS INC 0.5%
Value $5.927M Shares 436,156 Share Price $13.59 * Est. Cost/Share $3.56 Unrealized @ Report Date +164.5%
COO COOPER COS INC 0.4%
Value $5.098M Shares 74,363 Share Price $68.56 * Est. Cost/Share $70.83 Unrealized @ Report Date 0.0%
RYTM RHYTHM PHARMACEUTICALS INC 0.4%
Value $4.864M Shares 48,162 Share Price $100.99 * Est. Cost/Share $92.84 Unrealized @ Report Date 0.0%
VKTX VIKING THERAPEUTICS INC 0.4%
Value $4.823M Shares 183,538 Share Price $26.28 * Est. Cost/Share $29.11 Unrealized @ Report Date +2.5%
WST WEST PHARMACEUTICAL SVSC INC 0.4%
Value $4.818M Shares 18,365 Share Price $262.33 * Est. Cost/Share $242.79 Unrealized @ Report Date 0.0%
AZN ASTRAZENECA PLC 0.4%
Value $4.741M Shares 61,795 Share Price $76.72 Est. Cost/Share $76.72 Unrealized @ Report Date —
ARGX ARGENX SE 0.4%
Value $4.723M Shares 6,403 Share Price $737.56 Est. Cost/Share $395.24 Unrealized @ Report Date —
RZLT REZOLUTE INC 0.3%
Value $4.256M Shares 452,733 Share Price $9.40 * Est. Cost/Share $3.83 Unrealized @ Report Date +73.7%
SNDX SYNDAX PHARMACEUTICALS INC 0.3%
Value $3.946M Shares 256,488 Share Price $15.39 * Est. Cost/Share $13.09 Unrealized @ Report Date 0.0%
MBX MBX BIOSCIENCES INC 0.3%
Value $3.876M Shares 221,505 Share Price $17.50 * Est. Cost/Share $13.37 Unrealized @ Report Date 0.0%
AMRX AMNEAL PHARMACEUTICALS INC 0.3%
Value $3.562M Shares 355,818 Share Price $10.01 * Est. Cost/Share $8.98 Unrealized @ Report Date 0.0%
GPCR STRUCTURE THERAPEUTICS INC 0.2%
Value $3.222M Shares 115,073 Share Price $28.00 Est. Cost/Share $23.23 Unrealized @ Report Date —
PRAX PRAXIS PRECISION MEDICINES I 0.2%
Value $3.211M Shares 60,578 Share Price $53.00 * Est. Cost/Share $29.44 Unrealized @ Report Date +64.7%
ELVN ENLIVEN THERAPEUTICS INC 0.2%
Value $3.203M Shares 156,463 Share Price $20.47 Est. Cost/Share $20.16 Unrealized @ Report Date 0.0%
CRBU CARIBOU BIOSCIENCES INC 0.2%
Value $3.166M Shares 1,358,831 Share Price $2.33 * Est. Cost/Share $14.05 Unrealized @ Report Date -86.6%
BSX BOSTON SCIENTIFIC CORP 0.2%
Value $2.797M Shares 28,648 Share Price $97.63 * Est. Cost/Share $103.56 Unrealized @ Report Date 0.0%
QURE UNIQURE NV 0.2%
Value $2.706M Shares 46,353 Share Price $58.37 * Est. Cost/Share $10.89 Unrealized @ Report Date +66.7%
DNTH DIANTHUS THERAPEUTICS INC 0.2%
Value $2.67M Shares 67,840 Share Price $39.35 * Est. Cost/Share $25.56 Unrealized @ Report Date 0.0%
IRON DISC MEDICINE INC 0.2%
Value $2.15M Shares 32,539 Share Price $66.08 * Est. Cost/Share $47.64 Unrealized @ Report Date +24.9%
LQDA LIQUIDIA CORPORATION 0.1%
Value $1.735M Shares 76,300 Share Price $22.74 Est. Cost/Share — Unrealized @ Report Date —
HIMS HIMS & HERS HEALTH INC 0.1%
Value $1.3M Shares 22,915 Share Price $56.72 * Est. Cost/Share $51.24 Unrealized @ Report Date 0.0%
TMO THERMO FISHER SCIENTIFIC INC 0.1%
Value $1.122M Shares 2,314 Share Price $485.02 * Est. Cost/Share $464.78 Unrealized @ Report Date 0.0%
HUM HUMANA INC 0.1%
Value $949K Shares 3,648 Share Price $260.17 Est. Cost/Share $306.16 Unrealized @ Report Date -14.7%
— MIND MEDICINE MINDMED INC 0.1%
Value $886K Shares 75,138 Share Price $11.79 Est. Cost/Share $11.79 Unrealized @ Report Date —
HOWL WEREWOLF THERAPEUTICS INC 0.1%
Value $790K Shares 401,110 Share Price $1.97 * Est. Cost/Share $4.07 Unrealized @ Report Date -66.4%