PFM Health Sciences, LP Quant / Systematic

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
GKOS	GLAUKOS CORP	201,676	$22,771	2.3%	$95.54	0.0%	COM	377322102
MDT	MEDTRONIC PLC	213,796	$20,537	2.0%	$97.14	0.0%	SHS	G5960L103
SYK	STRYKER CORPORATION	50,852	$17,873	1.8%	$363.46	0.0%	COM	863667101
UNH	UNITEDHEALTH GROUP INC	50,539	$16,683	1.7%	$337.21	0.0%	COM	91324P102
CNC	CENTENE CORP DEL	372,300	$15,320	1.5%	$31.71	+18.0%	CALL	15135B101
DXCM	DEXCOM INC	227,357	$15,090	1.5%	$64.65	0.0%	COM	252131107
CAH	CARDINAL HEALTH INC	62,341	$12,811	1.3%	$187.72	0.0%	COM	14149Y108
TFX	TELEFLEX INCORPORATED	102,395	$12,496	1.2%	$121.00	0.0%	COM	879369106
GILD	GILEAD SCIENCES INC	71,018	$8,717	0.9%	$120.88	0.0%	COM	375558103
JAZZ	JAZZ PHARMACEUTICALS PLC	50,511	$8,587	0.9%	$153.31	0.0%	SHS USD	G50871105
SNY	SANOFI SA	176,413	$8,549	0.9%	$48.46	—	SPONSORED ADR	80105N105
IQV	IQVIA HLDGS INC	37,852	$8,532	0.9%	$217.58	0.0%	COM	46266C105
ITGR	INTEGER HLDGS CORP	106,585	$8,359	0.8%	$79.69	0.0%	COM	45826H109
BLLN	BILLIONTOONE INC	87,547	$7,165	0.7%	$101.40	0.0%	CL A	090168105
ALGN	ALIGN TECHNOLOGY INC	42,304	$6,606	0.7%	$143.30	0.0%	COM	016255101
PSNL	PERSONALIS INC	805,817	$6,414	0.6%	$8.75	0.0%	COM	71535D106
ELAN	ELANCO ANIMAL HEALTH INC	207,311	$4,691	0.5%	$21.76	0.0%	COM	28414H103
BTSG	BRIGHTSPRING HEALTH SVCS INC	118,525	$4,439	0.4%	$33.54	0.0%	COM	10950A106
ABVX	ABIVAX SA	31,878	$4,299	0.4%	$134.86	—	SPONSORED ADS	00370M103
MDGL	MADRIGAL PHARMACEUTICALS INC	7,258	$4,227	0.4%	$510.76	0.0%	COM	558868105
MOH	MOLINA HEALTHCARE INC	22,802	$3,957	0.4%	$164.37	0.0%	COM	60855R100
CLDX	CELLDEX THERAPEUTICS INC NEW	133,161	$3,617	0.4%	$26.34	0.0%	COM NEW	15117B202
MDLN	MEDLINE INC	85,000	$3,570	0.4%	$42.23	0.0%	COM CL A	58507V107
BLTE	BELITE BIO INC	19,823	$3,171	0.3%	$159.96	—	SPONSORED ADS	07782B104
FTRE	FORTREA HLDGS INC	165,439	$2,854	0.3%	$12.35	0.0%	COMMON STOCK	34965K107
CGEM	CULLINAN THERAPEUTICS INC	227,003	$2,349	0.2%	$9.02	0.0%	COM	230031106
TARS	TARSUS PHARMACEUTICALS INC	27,338	$2,238	0.2%	$74.67	0.0%	COM	87650L103
MLYS	MINERALYS THERAPEUTICS INC	47,637	$1,729	0.2%	$40.10	0.0%	COM	603170101
TECX	TECTONIC THERAPEUTIC INC	42,724	$891	0.1%	$18.58	0.0%	COM	878972108
NPCE	NEUROPACE INC	11,329	$175	0.0%	$13.37	0.0%	COM	641288105
TMCI	TREACE MED CONCEPTS INC	50,000	$123	0.0%	$4.34	0.0%	COM	89455T109

Increased Positions (13)

TMO THERMO FISHER SCIENTIFIC INC 2.2%

Value ($000) $21,970 (+1857.5%) Shares 37,915 (+1538.5%) Est. Cost $559.03 Unrealized +1.1%

NBIX NEUROCRINE BIOSCIENCES INC 2.3%

Value ($000) $23,146 (+188.0%) Shares 163,197 (+185.1%) Est. Cost $139.95 Unrealized +3.5%

AMRX AMNEAL PHARMACEUTICALS INC 1.8%

Value ($000) $18,465 (+418.4%) Shares 1,465,480 (+311.9%) Est. Cost $10.84 Unrealized +5.5%

INBX INHIBRX BIOSCIENCES INC 2.1%

Value ($000) $20,976 (+159.9%) Shares 265,517 (+10.8%) Est. Cost $19.46 Unrealized +250.0%

CNC CENTENE CORP DEL 3.0%

Value ($000) $29,851 (+45.7%) Shares 725,424 (+26.3%) Est. Cost $31.71 Unrealized +18.0%

ASND ASCENDIS PHARMA A/S 3.8%

Value ($000) $37,890 (+31.2%) Shares 177,685 (+22.3%) Est. Cost $167.20 Unrealized —

WAT WATERS CORP 1.6%

Value ($000) $16,412 (+78.0%) Shares 43,208 (+40.5%) Est. Cost $342.44 Unrealized +7.5%

ADMA ADMA BIOLOGICS INC 2.3%

Value ($000) $23,181 (+33.9%) Shares 1,270,894 (+7.6%) Est. Cost $17.12 Unrealized -1.6%

SLNO SOLENO THERAPEUTICS INC 1.1%

Value ($000) $11,477 (-30.2%) Shares 247,893 (+1.8%) Est. Cost $50.39 Unrealized +8.8%

COO COOPER COS INC 0.8%

Value ($000) $8,262 (+62.0%) Shares 100,802 (+35.6%) Est. Cost $71.88 Unrealized +4.1%

VKTX VIKING THERAPEUTICS INC 0.7%

Value ($000) $6,647 (+37.8%) Shares 188,956 (+3.0%) Est. Cost $29.29 Unrealized +21.0%

DNTH DIANTHUS THERAPEUTICS INC 0.4%

Value ($000) $4,104 (+53.7%) Shares 99,576 (+46.8%) Est. Cost $29.77 Unrealized +30.2%

CGON CG ONCOLOGY INC 0.7%

Value ($000) $6,808 (+7.1%) Shares 163,967 (+3.9%) Est. Cost $29.53 Unrealized +40.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
TMO	THERMO FISHER SCIENTIFIC INC	37,915 (+1538.5%)	$21,970 (+1857.5%)	2.2%	$559.03	+1.1%	COM	883556102
NBIX	NEUROCRINE BIOSCIENCES INC	163,197 (+185.1%)	$23,146 (+188.0%)	2.3%	$139.95	+3.5%	COM	64125C109
AMRX	AMNEAL PHARMACEUTICALS INC	1,465,480 (+311.9%)	$18,465 (+418.4%)	1.8%	$10.84	+5.5%	COM STK CL A	03168L105
INBX	INHIBRX BIOSCIENCES INC	265,517 (+10.8%)	$20,976 (+159.9%)	2.1%	$19.46	+250.0%	COM	45720N103
CNC	CENTENE CORP DEL	725,424 (+26.3%)	$29,851 (+45.7%)	3.0%	$31.71	+18.0%	COM	15135B101
ASND	ASCENDIS PHARMA A/S	177,685 (+22.3%)	$37,890 (+31.2%)	3.8%	$167.20	—	SPONSORED ADR	04351P101
WAT	WATERS CORP	43,208 (+40.5%)	$16,412 (+78.0%)	1.6%	$342.44	+7.5%	COM	941848103
ADMA	ADMA BIOLOGICS INC	1,270,894 (+7.6%)	$23,181 (+33.9%)	2.3%	$17.12	-1.6%	COM	000899104
SLNO	SOLENO THERAPEUTICS INC	247,893 (+1.8%)	$11,477 (-30.2%)	1.1%	$50.39	+8.8%	COM	834203309
COO	COOPER COS INC	100,802 (+35.6%)	$8,262 (+62.0%)	0.8%	$71.88	+4.1%	COM	216648501
VKTX	VIKING THERAPEUTICS INC	188,956 (+3.0%)	$6,647 (+37.8%)	0.7%	$29.29	+21.0%	COM	92686J106
DNTH	DIANTHUS THERAPEUTICS INC	99,576 (+46.8%)	$4,104 (+53.7%)	0.4%	$29.77	+30.2%	COM	252828108
CGON	CG ONCOLOGY INC	163,967 (+3.9%)	$6,808 (+7.1%)	0.7%	$29.53	+40.1%	COM	156944100

Exited Positions (25)

XBI SPDR SERIES TRUST 7.2%

Value ($000) $71,883 Shares 717,400 Est. Cost — Unrealized —

MCK MCKESSON CORP 5.6%

Value ($000) $55,865 Shares 72,313 Est. Cost $163.53 Unrealized +398.7%

HUM HUMANA INC 2.9%

Value ($000) $28,619 Shares 110,000 Est. Cost $306.16 Unrealized -14.6%

COR CENCORA INC 2.5%

Value ($000) $25,156 Shares 80,493 Est. Cost $289.07 Unrealized +17.8%

ELV ELEVANCE HEALTH INC FORMERLY 2.0%

Value ($000) $19,638 Shares 60,776 Est. Cost $308.14 Unrealized +9.3%

NTRA NATERA INC 1.9%

Value ($000) $18,607 Shares 115,596 Est. Cost $156.13 Unrealized +33.6%

SPY SPDR S&P 500 ETF TR 1.4%

Value ($000) $14,130 Shares 21,210 Est. Cost $627.15 Unrealized —

IWM ISHARES TR 1.4%

Value ($000) $13,719 Shares 56,700 Est. Cost — Unrealized —

— MERUS N V 1.2%

Value ($000) $12,309 Shares 130,742 Est. Cost $52.60 Unrealized —

BSX BOSTON SCIENTIFIC CORP 1.2%

Value ($000) $11,911 Shares 122,000 Est. Cost $103.56 Unrealized -5.3%

— AKERO THERAPEUTICS INC 1.2%

Value ($000) $11,779 Shares 248,079 Est. Cost $53.36 Unrealized —

REGN REGENERON PHARMACEUTICALS 1.1%

Value ($000) $11,184 Shares 19,890 Est. Cost $564.28 Unrealized +20.3%

IRTC IRHYTHM TECHNOLOGIES INC 1.1%

Value ($000) $11,179 Shares 64,998 Est. Cost $129.23 Unrealized +37.1%

— VERONA PHARMA PLC 0.9%

Value ($000) $8,581 Shares 80,416 Est. Cost $94.58 Unrealized —

TEVA TEVA PHARMACEUTICAL INDS LTD 0.7%

Value ($000) $7,208 Shares 356,818 Est. Cost $16.76 Unrealized —

ARQT ARCUTIS BIOTHERAPEUTICS INC 0.7%

Value ($000) $6,795 Shares 360,460 Est. Cost $14.02 Unrealized +82.6%

WST WEST PHARMACEUTICAL SVSC INC 0.5%

Value ($000) $4,818 Shares 18,365 Est. Cost $242.79 Unrealized +12.6%

AZN ASTRAZENECA PLC 0.5%

Value ($000) $4,741 Shares 61,795 Est. Cost $76.72 Unrealized —

ELVN ENLIVEN THERAPEUTICS INC 0.3%

Value ($000) $3,203 Shares 156,463 Est. Cost $20.16 Unrealized -1.2%

BSX BOSTON SCIENTIFIC CORP 0.3%

Value ($000) $2,797 Shares 28,648 Est. Cost $103.56 Unrealized -5.3%

LQDA LIQUIDIA CORPORATION 0.2%

Value ($000) $1,735 Shares 76,300 Est. Cost — Unrealized —

HIMS HIMS & HERS HEALTH INC 0.1%

Value ($000) $1,300 Shares 22,915 Est. Cost $51.24 Unrealized -16.4%

HUM HUMANA INC 0.1%

Value ($000) $949 Shares 3,648 Est. Cost $306.16 Unrealized -14.6%

— MIND MEDICINE MINDMED INC 0.1%

Value ($000) $886 Shares 75,138 Est. Cost $11.79 Unrealized —

HOWL WEREWOLF THERAPEUTICS INC 0.1%

Value ($000) $790 Shares 401,110 Est. Cost $4.07 Unrealized -70.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
XBI	SPDR SERIES TRUST	717,400	$71,883	7.2%	—	—	CALL	78464A870
MCK	MCKESSON CORP	72,313	$55,865	5.6%	$163.53	+398.7%	—	58155Q103
HUM	HUMANA INC	110,000	$28,619	2.9%	$306.16	-14.6%	CALL	444859102
COR	CENCORA INC	80,493	$25,156	2.5%	$289.07	+17.8%	—	03073E105
ELV	ELEVANCE HEALTH INC FORMERLY	60,776	$19,638	2.0%	$308.14	+9.3%	—	036752103
NTRA	NATERA INC	115,596	$18,607	1.9%	$156.13	+33.6%	—	632307104
SPY	SPDR S&P 500 ETF TR	21,210	$14,130	1.4%	$627.15	—	—	78462F103
IWM	ISHARES TR	56,700	$13,719	1.4%	—	—	PUT	464287655
—	MERUS N V	130,742	$12,309	1.2%	$52.60	—	—	N5749R100
BSX	BOSTON SCIENTIFIC CORP	122,000	$11,911	1.2%	$103.56	-5.3%	CALL	101137107
—	AKERO THERAPEUTICS INC	248,079	$11,779	1.2%	$53.36	—	—	00973Y108
REGN	REGENERON PHARMACEUTICALS	19,890	$11,184	1.1%	$564.28	+20.3%	—	75886F107
IRTC	IRHYTHM TECHNOLOGIES INC	64,998	$11,179	1.1%	$129.23	+37.1%	—	450056106
—	VERONA PHARMA PLC	80,416	$8,581	0.9%	$94.58	—	—	925050106
TEVA	TEVA PHARMACEUTICAL INDS LTD	356,818	$7,208	0.7%	$16.76	—	—	881624209
ARQT	ARCUTIS BIOTHERAPEUTICS INC	360,460	$6,795	0.7%	$14.02	+82.6%	—	03969K108
WST	WEST PHARMACEUTICAL SVSC INC	18,365	$4,818	0.5%	$242.79	+12.6%	—	955306105
AZN	ASTRAZENECA PLC	61,795	$4,741	0.5%	$76.72	—	—	046353108
ELVN	ENLIVEN THERAPEUTICS INC	156,463	$3,203	0.3%	$20.16	-1.2%	—	29337E102
BSX	BOSTON SCIENTIFIC CORP	28,648	$2,797	0.3%	$103.56	-5.3%	—	101137107
LQDA	LIQUIDIA CORPORATION	76,300	$1,735	0.2%	—	—	PUT	53635D202
HIMS	HIMS & HERS HEALTH INC	22,915	$1,300	0.1%	$51.24	-16.4%	—	433000106
HUM	HUMANA INC	3,648	$949	0.1%	$306.16	-14.6%	—	444859102
—	MIND MEDICINE MINDMED INC	75,138	$886	0.1%	$11.79	—	—	60255C885
HOWL	WEREWOLF THERAPEUTICS INC	401,110	$790	0.1%	$4.07	-70.1%	—	95075A107

Decreased Positions (34)

LLY ELI LILLY & CO 7.3%

Value ($000) $73,389 (-57.3%) Shares 68,289 (-69.7%) Est. Cost $156.24 Unrealized +511.6%

ISRG INTUITIVE SURGICAL INC 0.9%

Value ($000) $8,728 (-74.8%) Shares 15,410 (-80.1%) Est. Cost $358.21 Unrealized +48.6%

OM OUTSET MED INC 0.2%

Value ($000) $1,969 (-91.9%) Shares 530,796 (-69.3%) Est. Cost $12.06 Unrealized -28.9%

HCA HCA HEALTHCARE INC 0.6%

Value ($000) $6,473 (-76.9%) Shares 13,865 (-78.9%) Est. Cost $229.48 Unrealized +102.1%

AXSM AXSOME THERAPEUTICS INC 4.6%

Value ($000) $45,945 (-28.7%) Shares 251,562 (-52.6%) Est. Cost $54.98 Unrealized +153.9%

CVS CVS HEALTH CORP 0.9%

Value ($000) $8,552 (-67.3%) Shares 107,767 (-68.9%) Est. Cost $60.15 Unrealized +30.8%

THC TENET HEALTHCARE CORP 7.9%

Value ($000) $79,044 (-15.7%) Shares 397,767 (-13.8%) Est. Cost $52.95 Unrealized +281.7%

UHS UNIVERSAL HLTH SVCS INC 1.2%

Value ($000) $12,516 (-47.3%) Shares 57,409 (-50.6%) Est. Cost $179.65 Unrealized +23.0%

VERA VERA THERAPEUTICS INC 0.5%

Value ($000) $5,453 (-63.5%) Shares 107,690 (-79.0%) Est. Cost $23.13 Unrealized +53.6%

EW EDWARDS LIFESCIENCES CORP 2.1%

Value ($000) $21,043 (-29.0%) Shares 246,835 (-35.3%) Est. Cost $74.29 Unrealized +10.5%

OSCR OSCAR HEALTH INC 0.7%

Value ($000) $7,183 (-53.8%) Shares 499,837 (-39.1%) Est. Cost $11.78 Unrealized +46.9%

UTHR UNITED THERAPEUTICS CORP DEL 3.3%

Value ($000) $33,008 (-17.7%) Shares 67,743 (-29.2%) Est. Cost $322.06 Unrealized +44.6%

BBIO BRIDGEBIO PHARMA INC 2.3%

Value ($000) $23,445 (+38.0%) Shares 306,506 (-6.3%) Est. Cost $31.20 Unrealized +110.4%

PRAX PRAXIS PRECISION MEDICINES I 0.9%

Value ($000) $9,185 (+186.1%) Shares 31,163 (-48.6%) Est. Cost $29.44 Unrealized +532.7%

VEEV VEEVA SYS INC 0.7%

Value ($000) $7,253 (-41.3%) Shares 32,489 (-21.7%) Est. Cost $281.43 Unrealized -5.7%

AMLX AMYLYX PHARMACEUTICALS INC 0.2%

Value ($000) $1,625 (-72.6%) Shares 134,549 (-69.2%) Est. Cost $3.56 Unrealized +281.7%

PEN PENUMBRA INC 4.5%

Value ($000) $45,135 (-8.7%) Shares 145,171 (-25.6%) Est. Cost $201.49 Unrealized +37.1%

CMPS COMPASS PATHWAYS PLC 0.5%

Value ($000) $5,379 (-43.5%) Shares 779,618 (-53.1%) Est. Cost $4.25 Unrealized —

RZLT REZOLUTE INC 0.0%

Value ($000) $487 (-88.6%) Shares 206,265 (-54.4%) Est. Cost $3.83 Unrealized +104.5%

RVMD REVOLUTION MEDICINES INC 1.2%

Value ($000) $12,063 (-22.0%) Shares 151,453 (-54.3%) Est. Cost $39.15 Unrealized +67.5%

NEO NEOGENOMICS INC 2.0%

Value ($000) $19,922 (+16.8%) Shares 1,694,051 (-23.3%) Est. Cost $8.55 Unrealized +26.2%

ICLR ICON PLC 2.1%

Value ($000) $21,017 (-10.2%) Shares 115,336 (-13.7%) Est. Cost $174.03 Unrealized +2.3%

QURE UNIQURE NV 0.1%

Value ($000) $945 (-65.1%) Shares 39,499 (-14.8%) Est. Cost $10.89 Unrealized +254.3%

CRBU CARIBOU BIOSCIENCES INC 0.2%

Value ($000) $1,523 (-51.9%) Shares 957,787 (-29.5%) Est. Cost $14.05 Unrealized -85.1%

GPCR STRUCTURE THERAPEUTICS INC 0.5%

Value ($000) $4,747 (+47.3%) Shares 68,248 (-40.7%) Est. Cost $23.23 Unrealized —

MBX MBX BIOSCIENCES INC 0.2%

Value ($000) $2,501 (-35.5%) Shares 79,310 (-64.2%) Est. Cost $13.37 Unrealized +81.5%

CNTA CENTESSA PHARMACEUTICALS PLC 1.5%

Value ($000) $14,796 (-8.4%) Shares 591,601 (-11.2%) Est. Cost $18.33 Unrealized —

IRON DISC MEDICINE INC 0.1%

Value ($000) $874 (-59.4%) Shares 11,002 (-66.2%) Est. Cost $47.64 Unrealized +77.4%

ARGX ARGENX SE 0.4%

Value ($000) $3,534 (-25.2%) Shares 4,202 (-34.4%) Est. Cost $395.24 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 0.5%

Value ($000) $5,105 (+29.4%) Shares 242,967 (-5.3%) Est. Cost $13.09 Unrealized +33.3%

— INDIVIOR PLC 1.3%

Value ($000) $12,942 (-4.4%) Shares 360,695 (-35.8%) Est. Cost $10.28 Unrealized —

— ASCENDIS PHARMA A/S 1.5%

Value ($000) $15,135 (-3.6%) Shares 10,655,000 (-7.5%) Est. Cost $1.14 Unrealized —

RYTM RHYTHM PHARMACEUTICALS INC 0.4%

Value ($000) $4,304 (-11.5%) Shares 40,210 (-16.5%) Est. Cost $92.84 Unrealized +14.3%

MRK MERCK & CO INC 2.0%

Value ($000) $19,771 (-0.4%) Shares 187,834 (-20.6%) Est. Cost $81.01 Unrealized +15.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
LLY	ELI LILLY & CO	68,289 (-69.7%)	$73,389 (-57.3%)	7.3%	$156.24	+511.6%	COM	532457108
ISRG	INTUITIVE SURGICAL INC	15,410 (-80.1%)	$8,728 (-74.8%)	0.9%	$358.21	+48.6%	COM NEW	46120E602
OM	OUTSET MED INC	530,796 (-69.3%)	$1,969 (-91.9%)	0.2%	$12.06	-28.9%	COM NEW	690145206
HCA	HCA HEALTHCARE INC	13,865 (-78.9%)	$6,473 (-76.9%)	0.6%	$229.48	+102.1%	COM	40412C101
AXSM	AXSOME THERAPEUTICS INC	251,562 (-52.6%)	$45,945 (-28.7%)	4.6%	$54.98	+153.9%	COM	05464T104
CVS	CVS HEALTH CORP	107,767 (-68.9%)	$8,552 (-67.3%)	0.9%	$60.15	+30.8%	COM	126650100
THC	TENET HEALTHCARE CORP	397,767 (-13.8%)	$79,044 (-15.7%)	7.9%	$52.95	+281.7%	COM NEW	88033G407
UHS	UNIVERSAL HLTH SVCS INC	57,409 (-50.6%)	$12,516 (-47.3%)	1.2%	$179.65	+23.0%	CL B	913903100
VERA	VERA THERAPEUTICS INC	107,690 (-79.0%)	$5,453 (-63.5%)	0.5%	$23.13	+53.6%	CL A	92337R101
EW	EDWARDS LIFESCIENCES CORP	246,835 (-35.3%)	$21,043 (-29.0%)	2.1%	$74.29	+10.5%	COM	28176E108
OSCR	OSCAR HEALTH INC	499,837 (-39.1%)	$7,183 (-53.8%)	0.7%	$11.78	+46.9%	CL A	687793109
UTHR	UNITED THERAPEUTICS CORP DEL	67,743 (-29.2%)	$33,008 (-17.7%)	3.3%	$322.06	+44.6%	COM	91307C102
BBIO	BRIDGEBIO PHARMA INC	306,506 (-6.3%)	$23,445 (+38.0%)	2.3%	$31.20	+110.4%	COM	10806X102
PRAX	PRAXIS PRECISION MEDICINES I	31,163 (-48.6%)	$9,185 (+186.1%)	0.9%	$29.44	+532.7%	COM NEW	74006W207
VEEV	VEEVA SYS INC	32,489 (-21.7%)	$7,253 (-41.3%)	0.7%	$281.43	-5.7%	CL A COM	922475108
AMLX	AMYLYX PHARMACEUTICALS INC	134,549 (-69.2%)	$1,625 (-72.6%)	0.2%	$3.56	+281.7%	COM	03237H101
PEN	PENUMBRA INC	145,171 (-25.6%)	$45,135 (-8.7%)	4.5%	$201.49	+37.1%	COM	70975L107
CMPS	COMPASS PATHWAYS PLC	779,618 (-53.1%)	$5,379 (-43.5%)	0.5%	$4.25	—	SPONSORED ADS	20451W101
RZLT	REZOLUTE INC	206,265 (-54.4%)	$487 (-88.6%)	0.0%	$3.83	+104.5%	COM NEW	76200L309
RVMD	REVOLUTION MEDICINES INC	151,453 (-54.3%)	$12,063 (-22.0%)	1.2%	$39.15	+67.5%	COM	76155X100
NEO	NEOGENOMICS INC	1,694,051 (-23.3%)	$19,922 (+16.8%)	2.0%	$8.55	+26.2%	COM NEW	64049M209
ICLR	ICON PLC	115,336 (-13.7%)	$21,017 (-10.2%)	2.1%	$174.03	+2.3%	SHS	G4705A100
QURE	UNIQURE NV	39,499 (-14.8%)	$945 (-65.1%)	0.1%	$10.89	+254.3%	SHS	N90064101
CRBU	CARIBOU BIOSCIENCES INC	957,787 (-29.5%)	$1,523 (-51.9%)	0.2%	$14.05	-85.1%	COM	142038108
GPCR	STRUCTURE THERAPEUTICS INC	68,248 (-40.7%)	$4,747 (+47.3%)	0.5%	$23.23	—	SPONSORED ADS	86366E106
MBX	MBX BIOSCIENCES INC	79,310 (-64.2%)	$2,501 (-35.5%)	0.2%	$13.37	+81.5%	COM	55287L101
CNTA	CENTESSA PHARMACEUTICALS PLC	591,601 (-11.2%)	$14,796 (-8.4%)	1.5%	$18.33	—	SPONSORED ADS	152309100
IRON	DISC MEDICINE INC	11,002 (-66.2%)	$874 (-59.4%)	0.1%	$47.64	+77.4%	COM	254604101
ARGX	ARGENX SE	4,202 (-34.4%)	$3,534 (-25.2%)	0.4%	$395.24	—	SPONSORED ADR	04016X101
SNDX	SYNDAX PHARMACEUTICALS INC	242,967 (-5.3%)	$5,105 (+29.4%)	0.5%	$13.09	+33.3%	COM	87164F105
—	INDIVIOR PLC	360,695 (-35.8%)	$12,942 (-4.4%)	1.3%	$10.28	—	ORD	G4766E116
—	ASCENDIS PHARMA A/S	10,655,000 (-7.5%)	$15,135 (-3.6%)	1.5%	$1.14	—	NOTE 2.250% 4/0	04351PAD3
RYTM	RHYTHM PHARMACEUTICALS INC	40,210 (-16.5%)	$4,304 (-11.5%)	0.4%	$92.84	+14.3%	COM	76243J105
MRK	MERCK & CO INC	187,834 (-20.6%)	$19,771 (-0.4%)	2.0%	$81.01	+15.1%	COM	58933Y105