PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value: $1.003B (98.5% shares, 1.5% debt)

Holdings (78)

THC TENET HEALTHCARE CORP 7.9%
Value $79.04M Shares 397,767 Share Price $198.72 Est. Cost/Share $52.95 Unrealized @ Report Date +281.7%
LLY ELI LILLY & CO 7.3%
Value $73.39M Shares 68,289 Share Price $1074.68 * Est. Cost/Share $156.24 Unrealized @ Report Date +511.6%
AXSM AXSOME THERAPEUTICS INC 4.6%
Value $45.95M Shares 251,562 Share Price $182.64 * Est. Cost/Share $54.98 Unrealized @ Report Date +153.9%
PEN PENUMBRA INC 4.5%
Value $45.14M Shares 145,171 Share Price $310.91 * Est. Cost/Share $201.49 Unrealized @ Report Date +37.1%
ASND ASCENDIS PHARMA A/S 3.8%
Value $37.89M Shares 177,685 Share Price $213.24 Est. Cost/Share $167.20 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP DEL 3.3%
Value $33.01M Shares 67,743 Share Price $487.25 * Est. Cost/Share $322.06 Unrealized @ Report Date +44.6%
CNC CENTENE CORP DEL 3.0%
Value $29.85M Shares 725,424 Share Price $41.15 * Est. Cost/Share $31.71 Unrealized @ Report Date +18.0%
BBIO BRIDGEBIO PHARMA INC 2.3%
Value $23.44M Shares 306,506 Share Price $76.49 * Est. Cost/Share $31.20 Unrealized @ Report Date +110.4%
ADMA ADMA BIOLOGICS INC 2.3%
Value $23.18M Shares 1,270,894 Share Price $18.24 * Est. Cost/Share $17.12 Unrealized @ Report Date -1.6%
NBIX NEUROCRINE BIOSCIENCES INC 2.3%
Value $23.15M Shares 163,197 Share Price $141.83 * Est. Cost/Share $139.95 Unrealized @ Report Date +3.5%
GKOS GLAUKOS CORP 2.3%
Value $22.77M Shares 201,676 Share Price $112.91 * Est. Cost/Share $95.54 Unrealized @ Report Date 0.0%
TMO THERMO FISHER SCIENTIFIC INC 2.2%
Value $21.97M Shares 37,915 Share Price $579.45 * Est. Cost/Share $559.03 Unrealized @ Report Date +1.1%
EW EDWARDS LIFESCIENCES CORP 2.1%
Value $21.04M Shares 246,835 Share Price $85.25 * Est. Cost/Share $74.29 Unrealized @ Report Date +10.5%
ICLR ICON PLC 2.1%
Value $21.02M Shares 115,336 Share Price $182.22 * Est. Cost/Share $174.03 Unrealized @ Report Date +2.3%
INBX INHIBRX BIOSCIENCES INC 2.1%
Value $20.98M Shares 265,517 Share Price $79.00 * Est. Cost/Share $19.46 Unrealized @ Report Date +250.0%
MDT MEDTRONIC PLC 2.0%
Value $20.54M Shares 213,796 Share Price $96.06 Est. Cost/Share $97.14 Unrealized @ Report Date 0.0%
NEO NEOGENOMICS INC 2.0%
Value $19.92M Shares 1,694,051 Share Price $11.76 * Est. Cost/Share $8.55 Unrealized @ Report Date +26.2%
MRK MERCK & CO INC 2.0%
Value $19.77M Shares 187,834 Share Price $105.26 * Est. Cost/Share $81.01 Unrealized @ Report Date +15.1%
AMRX AMNEAL PHARMACEUTICALS INC 1.8%
Value $18.47M Shares 1,465,480 Share Price $12.60 * Est. Cost/Share $10.84 Unrealized @ Report Date +5.5%
SYK STRYKER CORPORATION 1.8%
Value $17.87M Shares 50,852 Share Price $351.47 * Est. Cost/Share $363.46 Unrealized @ Report Date 0.0%
UNH UNITEDHEALTH GROUP INC 1.7%
Value $16.68M Shares 50,539 Share Price $330.11 * Est. Cost/Share $337.21 Unrealized @ Report Date 0.0%
WAT WATERS CORP 1.6%
Value $16.41M Shares 43,208 Share Price $379.83 * Est. Cost/Share $342.44 Unrealized @ Report Date +7.5%
CNC CENTENE CORP DEL 1.5%
Value $15.32M Shares 372,300 Share Price $41.15 * Est. Cost/Share $31.71 Unrealized @ Report Date +18.0%
— ASCENDIS PHARMA A/S 1.5%
Value $15.13M Shares 10,655,000 Share Price $1.42 Est. Cost/Share $1.14 Unrealized @ Report Date —
DXCM DEXCOM INC 1.5%
Value $15.09M Shares 227,357 Share Price $66.37 * Est. Cost/Share $64.65 Unrealized @ Report Date 0.0%
CNTA CENTESSA PHARMACEUTICALS PLC 1.5%
Value $14.8M Shares 591,601 Share Price $25.01 Est. Cost/Share $18.33 Unrealized @ Report Date —
— INDIVIOR PLC 1.3%
Value $12.94M Shares 360,695 Share Price $35.88 Est. Cost/Share $10.28 Unrealized @ Report Date —
CAH CARDINAL HEALTH INC 1.3%
Value $12.81M Shares 62,341 Share Price $205.50 * Est. Cost/Share $187.72 Unrealized @ Report Date 0.0%
UHS UNIVERSAL HLTH SVCS INC 1.2%
Value $12.52M Shares 57,409 Share Price $218.02 Est. Cost/Share $179.65 Unrealized @ Report Date +23.0%
TFX TELEFLEX INCORPORATED 1.2%
Value $12.5M Shares 102,395 Share Price $122.04 Est. Cost/Share $121.00 Unrealized @ Report Date 0.0%
RVMD REVOLUTION MEDICINES INC 1.2%
Value $12.06M Shares 151,453 Share Price $79.65 * Est. Cost/Share $39.15 Unrealized @ Report Date +67.5%
SLNO SOLENO THERAPEUTICS INC 1.1%
Value $11.48M Shares 247,893 Share Price $46.30 * Est. Cost/Share $50.39 Unrealized @ Report Date +8.8%
PRAX PRAXIS PRECISION MEDICINES I 0.9%
Value $9.185M Shares 31,163 Share Price $294.74 * Est. Cost/Share $29.44 Unrealized @ Report Date +532.7%
ISRG INTUITIVE SURGICAL INC 0.9%
Value $8.728M Shares 15,410 Share Price $566.36 * Est. Cost/Share $358.21 Unrealized @ Report Date +48.6%
GILD GILEAD SCIENCES INC 0.9%
Value $8.717M Shares 71,018 Share Price $122.74 Est. Cost/Share $120.88 Unrealized @ Report Date 0.0%
JAZZ JAZZ PHARMACEUTICALS PLC 0.9%
Value $8.587M Shares 50,511 Share Price $170.00 * Est. Cost/Share $153.31 Unrealized @ Report Date 0.0%
CVS CVS HEALTH CORP 0.9%
Value $8.552M Shares 107,767 Share Price $79.36 Est. Cost/Share $60.15 Unrealized @ Report Date +30.8%
SNY SANOFI SA 0.9%
Value $8.549M Shares 176,413 Share Price $48.46 Est. Cost/Share $48.46 Unrealized @ Report Date —
IQV IQVIA HLDGS INC 0.9%
Value $8.532M Shares 37,852 Share Price $225.41 * Est. Cost/Share $217.58 Unrealized @ Report Date 0.0%
ITGR INTEGER HLDGS CORP 0.8%
Value $8.359M Shares 106,585 Share Price $78.43 Est. Cost/Share $79.69 Unrealized @ Report Date 0.0%
COO COOPER COS INC 0.8%
Value $8.262M Shares 100,802 Share Price $81.96 * Est. Cost/Share $71.88 Unrealized @ Report Date +4.1%
VEEV VEEVA SYS INC 0.7%
Value $7.253M Shares 32,489 Share Price $223.23 * Est. Cost/Share $281.43 Unrealized @ Report Date -5.7%
OSCR OSCAR HEALTH INC 0.7%
Value $7.183M Shares 499,837 Share Price $14.37 * Est. Cost/Share $11.78 Unrealized @ Report Date +46.9%
BLLN BILLIONTOONE INC 0.7%
Value $7.165M Shares 87,547 Share Price $81.84 * Est. Cost/Share $101.40 Unrealized @ Report Date 0.0%
CGON CG ONCOLOGY INC 0.7%
Value $6.808M Shares 163,967 Share Price $41.52 Est. Cost/Share $29.53 Unrealized @ Report Date +40.1%
VKTX VIKING THERAPEUTICS INC 0.7%
Value $6.647M Shares 188,956 Share Price $35.18 Est. Cost/Share $29.29 Unrealized @ Report Date +21.0%
ALGN ALIGN TECHNOLOGY INC 0.7%
Value $6.606M Shares 42,304 Share Price $156.15 * Est. Cost/Share $143.30 Unrealized @ Report Date 0.0%
HCA HCA HEALTHCARE INC 0.6%
Value $6.473M Shares 13,865 Share Price $466.86 Est. Cost/Share $229.48 Unrealized @ Report Date +102.1%
PSNL PERSONALIS INC 0.6%
Value $6.414M Shares 805,817 Share Price $7.96 * Est. Cost/Share $8.75 Unrealized @ Report Date 0.0%
VERA VERA THERAPEUTICS INC 0.5%
Value $5.453M Shares 107,690 Share Price $50.64 * Est. Cost/Share $23.13 Unrealized @ Report Date +53.6%
CMPS COMPASS PATHWAYS PLC 0.5%
Value $5.379M Shares 779,618 Share Price $6.90 Est. Cost/Share $4.25 Unrealized @ Report Date —
SNDX SYNDAX PHARMACEUTICALS INC 0.5%
Value $5.105M Shares 242,967 Share Price $21.01 * Est. Cost/Share $13.09 Unrealized @ Report Date +33.3%
GPCR STRUCTURE THERAPEUTICS INC 0.5%
Value $4.747M Shares 68,248 Share Price $69.55 Est. Cost/Share $23.23 Unrealized @ Report Date —
ELAN ELANCO ANIMAL HEALTH INC 0.5%
Value $4.691M Shares 207,311 Share Price $22.63 * Est. Cost/Share $21.76 Unrealized @ Report Date 0.0%
BTSG BRIGHTSPRING HEALTH SVCS INC 0.4%
Value $4.439M Shares 118,525 Share Price $37.45 * Est. Cost/Share $33.54 Unrealized @ Report Date 0.0%
RYTM RHYTHM PHARMACEUTICALS INC 0.4%
Value $4.304M Shares 40,210 Share Price $107.04 Est. Cost/Share $92.84 Unrealized @ Report Date +14.3%
ABVX ABIVAX SA 0.4%
Value $4.299M Shares 31,878 Share Price $134.86 Est. Cost/Share $134.86 Unrealized @ Report Date —
MDGL MADRIGAL PHARMACEUTICALS INC 0.4%
Value $4.227M Shares 7,258 Share Price $582.34 * Est. Cost/Share $510.76 Unrealized @ Report Date 0.0%
DNTH DIANTHUS THERAPEUTICS INC 0.4%
Value $4.104M Shares 99,576 Share Price $41.21 * Est. Cost/Share $29.77 Unrealized @ Report Date +30.2%
MOH MOLINA HEALTHCARE INC 0.4%
Value $3.957M Shares 22,802 Share Price $173.54 * Est. Cost/Share $164.37 Unrealized @ Report Date 0.0%
CLDX CELLDEX THERAPEUTICS INC NEW 0.4%
Value $3.617M Shares 133,161 Share Price $27.16 * Est. Cost/Share $26.34 Unrealized @ Report Date 0.0%
MDLN MEDLINE INC 0.4%
Value $3.57M Shares 85,000 Share Price $42.00 Est. Cost/Share $42.23 Unrealized @ Report Date 0.0%
ARGX ARGENX SE 0.4%
Value $3.534M Shares 4,202 Share Price $840.95 Est. Cost/Share $395.24 Unrealized @ Report Date —
BLTE BELITE BIO INC 0.3%
Value $3.171M Shares 19,823 Share Price $159.96 Est. Cost/Share $159.96 Unrealized @ Report Date —
FTRE FORTREA HLDGS INC 0.3%
Value $2.854M Shares 165,439 Share Price $17.25 * Est. Cost/Share $12.35 Unrealized @ Report Date 0.0%
MBX MBX BIOSCIENCES INC 0.2%
Value $2.501M Shares 79,310 Share Price $31.54 * Est. Cost/Share $13.37 Unrealized @ Report Date +81.5%
CGEM CULLINAN THERAPEUTICS INC 0.2%
Value $2.349M Shares 227,003 Share Price $10.35 * Est. Cost/Share $9.02 Unrealized @ Report Date 0.0%
TARS TARSUS PHARMACEUTICALS INC 0.2%
Value $2.238M Shares 27,338 Share Price $81.88 * Est. Cost/Share $74.67 Unrealized @ Report Date 0.0%
OM OUTSET MED INC 0.2%
Value $1.969M Shares 530,796 Share Price $3.71 * Est. Cost/Share $12.06 Unrealized @ Report Date -28.9%
MLYS MINERALYS THERAPEUTICS INC 0.2%
Value $1.729M Shares 47,637 Share Price $36.29 * Est. Cost/Share $40.10 Unrealized @ Report Date 0.0%
AMLX AMYLYX PHARMACEUTICALS INC 0.2%
Value $1.625M Shares 134,549 Share Price $12.08 * Est. Cost/Share $3.56 Unrealized @ Report Date +281.7%
CRBU CARIBOU BIOSCIENCES INC 0.2%
Value $1.523M Shares 957,787 Share Price $1.59 * Est. Cost/Share $14.05 Unrealized @ Report Date -85.1%
QURE UNIQURE NV 0.1%
Value $945K Shares 39,499 Share Price $23.93 * Est. Cost/Share $10.89 Unrealized @ Report Date +254.3%
TECX TECTONIC THERAPEUTIC INC 0.1%
Value $891K Shares 42,724 Share Price $20.86 * Est. Cost/Share $18.58 Unrealized @ Report Date 0.0%
IRON DISC MEDICINE INC 0.1%
Value $874K Shares 11,002 Share Price $79.41 * Est. Cost/Share $47.64 Unrealized @ Report Date +77.4%
RZLT REZOLUTE INC 0.0%
Value $487K Shares 206,265 Share Price $2.36 * Est. Cost/Share $3.83 Unrealized @ Report Date +104.5%
NPCE NEUROPACE INC 0.0%
Value $175K Shares 11,329 Share Price $15.44 * Est. Cost/Share $13.37 Unrealized @ Report Date 0.0%
TMCI TREACE MED CONCEPTS INC 0.0%
Value $123K Shares 50,000 Share Price $2.45 * Est. Cost/Share $4.34 Unrealized @ Report Date 0.0%