Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q4 2023 (← Previous) (Next →)
Filing Date: Feb 14, 2024
Total Value: $6.402B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| RCKT | ROCKET PHARMACEUTICALS INC | 17,687,772 | $530M | 8.3% | $17.75 | +24.3% | COM | 77313F106 |
| IMCR | IMMUNOCORE HLDGS PLC | 6,096,387 | $417M | 6.5% | $43.23 | — | ADS | 45258D105 |
| — | MIRATI THERAPEUTICS INC | 6,768,514 | $398M | 6.2% | $59.30 | — | COM | 60468T105 |
| AXSM | AXSOME THERAPEUTICS INC | 4,489,596 | $357M | 5.6% | $55.43 | +20.6% | COM | 05464T104 |
| ACAD | ACADIA PHARMACEUTICALS INC | 11,253,551 | $352M | 5.5% | $20.61 | +15.9% | COM | 004225108 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 6,887,086 | $329M | 5.1% | $50.64 | -23.4% | COM | 90400D108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,640,559 | $314M | 4.9% | $95.85 | +77.7% | COM | 02043Q107 |
| ARGX | ARGENX SE | 667,195 | $254M | 4.0% | $344.30 | — | SPONSORED ADR | 04016X101 |
| BRKR | BRUKER CORP | 3,344,095 | $246M | 3.8% | $72.95 | -12.9% | COM | 116794108 |
| CYTK | CYTOKINETICS INC | 2,525,080 | $211M | 3.3% | $26.72 | +35.5% | COM NEW | 23282W605 |
| PTCT | PTC THERAPEUTICS INC | 7,423,970 | $205M | 3.2% | $38.04 | -39.9% | COM | 69366J200 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 815,191 | $189M | 2.9% | $202.47 | -13.6% | COM | 558868105 |
| ARVN | ARVINAS INC | 4,213,483 | $173M | 2.7% | $23.38 | 0.0% | COM | 04335A105 |
| MASI | MASIMO CORP | 1,462,400 | $171M | 2.7% | $166.52 | -44.0% | COM | 574795100 |
| PEN | PENUMBRA INC | 662,664 | $167M | 2.6% | $259.17 | -14.7% | COM | 70975L107 |
| NTRA | NATERA INC | 2,593,323 | $162M | 2.5% | $42.76 | +16.8% | COM | 632307104 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 3,463,201 | $137M | 2.1% | $11.47 | +156.4% | COM NEW | 15117B202 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 5,315,514 | $122M | 1.9% | $21.97 | -20.4% | COM | 74366E102 |
| — | CARGO THERAPEUTICS INC | 5,175,832 | $120M | 1.9% | $23.15 | — | COM | 14179K101 |
| VCEL | VERICEL CORP | 3,212,794 | $114M | 1.8% | $13.91 | +150.4% | COM | 92346J108 |
| — | SAGE THERAPEUTICS INC | 5,197,019 | $113M | 1.8% | $20.58 | — | COM | 78667J108 |
| ALKS | ALKERMES PLC | 3,901,523 | $108M | 1.7% | $26.74 | -2.8% | SHS | G01767105 |
| — | AVADEL PHARMACEUTICALS PLC | 6,947,918 | $98.1M | 1.5% | $9.17 | — | SPONSORED ADR | 05337M104 |
| TXG | 10X GENOMICS INC | 1,549,951 | $86.74M | 1.4% | $60.97 | -28.6% | CL A COM | 88025U109 |
| — | AKERO THERAPEUTICS INC | 3,592,759 | $83.89M | 1.3% | $23.35 | — | COM | 00973Y108 |
| — | MERUS N V | 2,373,625 | $65.27M | 1.0% | $25.42 | — | COM | N5749R100 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,494,138 | $64.57M | 1.0% | $27.31 | +7.2% | COM | G31249108 |
| TARS | TARSUS PHARMACEUTICALS INC | 3,152,341 | $63.83M | 1.0% | $24.34 | -31.4% | COM | 87650L103 |
| — | 89BIO INC | 5,578,931 | $62.32M | 1.0% | $11.17 | — | COM | 282559103 |
| RNAM | AVIDITY BIOSCIENCES INC | 6,689,789 | $60.54M | 0.9% | $25.00 | -73.3% | COM | 05370A108 |
| APGE | APOGEE THERAPEUTICS INC | 2,142,591 | $59.86M | 0.9% | $22.03 | -9.0% | COM | 03770N101 |
| INSM | INSMED INC | 1,865,108 | $57.8M | 0.9% | $20.78 | +24.8% | COM PAR $.01 | 457669307 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 5,620,640 | $51.32M | 0.8% | $11.90 | -42.6% | COM | 68572M106 |
| SYRE | SPYRE THERAPEUTICS INC | 2,232,760 | $48.05M | 0.8% | $13.78 | 0.0% | COM NEW | 00773J202 |
| FULC | FULCRUM THERAPEUTICS INC | 5,469,956 | $36.92M | 0.6% | $10.55 | -57.9% | COM | 359616109 |
| TSHA | TAYSHA GENE THERAPIES INC | 16,893,185 | $29.9M | 0.5% | $1.87 | +6.7% | COM SHS | 877619106 |
| DHR | DANAHER CORPORATION | 118,584 | $27.43M | 0.4% | $210.35 | 0.0% | COM | 235851102 |
| TMO | THERMO FISHER SCIENTIFIC INC | 50,000 | $26.54M | 0.4% | $545.57 | -11.9% | COM | 883556102 |
| URGN | UROGEN PHARMA LTD | 1,726,808 | $25.9M | 0.4% | $14.41 | -9.9% | COM | M96088105 |
| RDNT | RADNET INC | 663,602 | $23.07M | 0.4% | $31.57 | 0.0% | COM | 750491102 |
| — | SPRINGWORKS THERAPEUTICS INC | 625,000 | $22.81M | 0.4% | $36.50 | — | COM | 85205L107 |
| STOK | STOKE THERAPEUTICS INC | 4,131,045 | $21.73M | 0.3% | $24.53 | -82.6% | COM | 86150R107 |
| TNGX | TANGO THERAPEUTICS INC | 1,966,752 | $19.47M | 0.3% | $8.68 | 0.0% | COM | 87583X109 |
| GHRS | GH RESEARCH PLC | 3,327,129 | $19.3M | 0.3% | $17.34 | -59.3% | ORDINARY SHARES | G3855L106 |
| ROIV | ROIVANT SCIENCES LTD | 1,454,273 | $16.33M | 0.3% | $8.28 | +17.7% | SHS | G76279101 |
| IMTX | IMMATICS N.V | 1,484,911 | $15.64M | 0.2% | $9.90 | -7.0% | SHS | N44445109 |
| — | ESSA PHARMA INC | 2,298,662 | $15.17M | 0.2% | $6.60 | — | COM NEW | 29668H708 |
| GH | GUARDANT HEALTH INC | 492,977 | $13.34M | 0.2% | $85.83 | -69.4% | COM | 40131M109 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 605,816 | $13.19M | 0.2% | $15.79 | 0.0% | COM | 92790C104 |
| — | ALLURION TECHNOLOGIES INC | 3,457,707 | $12.93M | 0.2% | $4.30 | — | COM SHS | 02008G102 |
| — | SHOCKWAVE MED INC | 65,060 | $12.4M | 0.2% | $199.10 | — | COM | 82489T104 |
| — | TOURMALINE BIO INC | 398,850 | $10.44M | 0.2% | $26.18 | — | COM | 89157D105 |
| — | ADICET BIO INC | 4,134,631 | $7.814M | 0.1% | $16.61 | — | COM | 007002108 |
| — | ACELYRIN INC | 978,310 | $7.298M | 0.1% | $20.90 | — | COM | 00445A100 |
| IMUX | IMMUNIC INC | 4,335,255 | $6.503M | 0.1% | $8.90 | -86.2% | COM | 4525EP101 |
| — | CUTERA INC | 1,817,585 | $6.407M | 0.1% | $46.88 | — | COM | 232109108 |
| — | SAB BIOTHERAPEUTICS INC | 9,178,282 | $6.31M | 0.1% | $0.69 | — | COM | 78397T103 |
| MIST | MILESTONE PHARMACEUTICALS IN | 3,256,102 | $5.438M | 0.1% | $20.06 | -86.5% | COM | 59935V107 |
| XGN | EXAGEN INC | 1,504,602 | $2.994M | 0.0% | $11.83 | -85.4% | COM | 30068X103 |
| APYX | APYX MEDICAL CORPORATION | 1,025,963 | $2.688M | 0.0% | $7.55 | -67.9% | COM | 03837C106 |
| — | ARYA SCIENCES ACQU CORP IV | 127,970 | $1.395M | 0.0% | $10.47 | — | CL A | G31659108 |
| SGHT | SIGHT SCIENCES INC | 164,806 | $850K | 0.0% | $3.09 | 0.0% | COM | 82657M105 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 350,000 | $172K | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |
| — | SIENTRA INC | 81,016 | $49,420 | 0.0% | $2.78 | — | COM | 82621J204 |