Opaleye Management Inc. Quant / Systematic

Location: Boston, MA

CIK: 0001595855 · Show all filings

Period: Q4 2013 (Next →)

Filing Date: Feb 14, 2014

Total Value: $127.4B (100.0% shares, 0.0% debt)

Holdings (23)

— GENTIUM S P A 23.0%

Value $29.24B Shares 505,000 Est. Cost $57900.00 Unrealized —

GERN GERON CORP 10.4%

Value $13.2B Shares 2,640,000 Est. Cost $4.29 Unrealized 0.0%

— PHARMACYCLICS INC 10.2%

Value $12.96B Shares 120,000 Est. Cost $108000.00 Unrealized —

— ARIAD PHARMACEUTICALS INC 9.3%

Value $11.86B Shares 1,670,000 Est. Cost $7100.00 Unrealized —

— NPS PHARMACEUTICALS INC 4.7%

Value $5.945B Shares 205,000 Est. Cost $29000.00 Unrealized —

OMER OMEROS CORP 4.0%

Value $5.06B Shares 460,000 Est. Cost $9.65 Unrealized 0.0%

LAB FLUIDIGM CORP DEL 4.0%

Value $5.035B Shares 132,500 Est. Cost $29.45 Unrealized 0.0%

LGND LIGAND PHARMACEUTICALS INC 3.8%

Value $4.86B Shares 90,000 Est. Cost $32.58 Unrealized 0.0%

— CEMPRA INC 3.7%

Value $4.745B Shares 365,000 Est. Cost $13000.00 Unrealized —

— CARDIOVASCULAR SYS INC DEL 3.5%

Value $4.455B Shares 135,000 Est. Cost $33000.00 Unrealized —

— SUNSHINE HEART INC 3.2%

Value $4.123B Shares 425,100 Est. Cost $9700.00 Unrealized —

— INTERCEPT PHARMACEUTICALS INC 2.9%

Value $3.642B Shares 56,900 Est. Cost $64000.00 Unrealized —

— INSPIREMD INC 2.3%

Value $2.949B Shares 1,134,400 Est. Cost $2600.00 Unrealized —

— NOVADAQ TECHNOLOGIES INC 2.2%

Value $2.849B Shares 167,600 Est. Cost $17000.00 Unrealized —

CPRX CATALYST PHARM PARTNERS INC 2.1%

Value $2.64B Shares 1,353,900 Est. Cost $2.02 Unrealized 0.0%

— CELGENE CORP 1.8%

Value $2.24B Shares 800,000 Est. Cost $2800.00 Unrealized —

— BIND THERAPEUTICS INC 1.7%

Value $2.123B Shares 155,000 Est. Cost $13700.00 Unrealized —

— BIOLINERX LTD 1.6%

Value $2.068B Shares 713,000 Est. Cost $2900.00 Unrealized —

— TETRAPHASE PHARMACEUTICALS INC 1.6%

Value $1.996B Shares 153,500 Est. Cost $13000.00 Unrealized —

INFIQ INFINITY PHARMACEUTICALS INC 1.3%

Value $1.671B Shares 130,000 Est. Cost $14.12 Unrealized 0.0%

— MEDIVATION INC 1.3%

Value $1.6B Shares 25,000 Est. Cost $64000.00 Unrealized —

— KALOBIOS PHARMACEUTICALS INC 0.9%

Value $1.169B Shares 285,000 Est. Cost $4100.00 Unrealized —

— CELATOR PHARMACEUTICALS INC 0.8%

Value $961M Shares 310,000 Est. Cost $3100.00 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	GENTIUM S P A	505,000	$29.24B	23.0%	$57900.00	—	SPONSORED ADR	37250B104
GERN	GERON CORP	2,640,000	$13.2B	10.4%	$4.29	0.0%	COM	374163103
—	PHARMACYCLICS INC	120,000	$12.96B	10.2%	$108000.00	—	COM	716933106
—	ARIAD PHARMACEUTICALS INC	1,670,000	$11.86B	9.3%	$7100.00	—	COM	04033A100
—	NPS PHARMACEUTICALS INC	205,000	$5.945B	4.7%	$29000.00	—	COM	62936P103
OMER	OMEROS CORP	460,000	$5.06B	4.0%	$9.65	0.0%	COM	682143102
LAB	FLUIDIGM CORP DEL	132,500	$5.035B	4.0%	$29.45	0.0%	COM	34385P108
LGND	LIGAND PHARMACEUTICALS INC	90,000	$4.86B	3.8%	$32.58	0.0%	COM	53220K504
—	CEMPRA INC	365,000	$4.745B	3.7%	$13000.00	—	COM	15130J109
—	CARDIOVASCULAR SYS INC DEL	135,000	$4.455B	3.5%	$33000.00	—	COM	141619106
—	SUNSHINE HEART INC	425,100	$4.123B	3.2%	$9700.00	—	COM	86782U106
—	INTERCEPT PHARMACEUTICALS INC	56,900	$3.642B	2.9%	$64000.00	—	COM	45845P108
—	INSPIREMD INC	1,134,400	$2.949B	2.3%	$2600.00	—	COM NEW	45779A309
—	NOVADAQ TECHNOLOGIES INC	167,600	$2.849B	2.2%	$17000.00	—	COM	66987G102
CPRX	CATALYST PHARM PARTNERS INC	1,353,900	$2.64B	2.1%	$2.02	0.0%	COM	14888U101
—	CELGENE CORP	800,000	$2.24B	1.8%	$2800.00	—	RIGHT 12/31/2030	151020112
—	BIND THERAPEUTICS INC	155,000	$2.123B	1.7%	$13700.00	—	COM	05548N107
—	BIOLINERX LTD	713,000	$2.068B	1.6%	$2900.00	—	SPONSORED ADR	09071M106
—	TETRAPHASE PHARMACEUTICALS INC	153,500	$1.996B	1.6%	$13000.00	—	COM	88165N105
INFIQ	INFINITY PHARMACEUTICALS INC	130,000	$1.671B	1.3%	$14.12	0.0%	COM	45665G303
—	MEDIVATION INC	25,000	$1.6B	1.3%	$64000.00	—	COM	58501N101
—	KALOBIOS PHARMACEUTICALS INC	285,000	$1.169B	0.9%	$4100.00	—	COM	48344T100
—	CELATOR PHARMACEUTICALS INC	310,000	$961M	0.8%	$3100.00	—	COM	15089R102