Location: San Francisco, CA
CIK: 0001587114 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $3.138B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | 11,284,280 | $557M | 17.8% | $10.98 | +404.8% | SHS | G72800108 |
| ANAB | ANAPTYSBIO INC | 7,521,024 | $261M | 8.3% | $23.15 | +37.0% | COM | 032724106 |
| RCUS | ARCUS BIOSCIENCES INC | 5,523,358 | $224M | 7.1% | $28.65 | +35.4% | COM | 03969F109 |
| XNCR | XENCOR INC | 4,906,106 | $197M | 6.3% | $34.08 | +11.2% | COM | 98401F105 |
| APLS | APELLIS PHARMACEUTICALS INC | 4,033,882 | $191M | 6.1% | $39.37 | 0.0% | COM | 03753U106 |
| — | MORPHIC HLDG INC | 3,951,566 | $187M | 6.0% | $29.75 | — | COM | 61775R105 |
| GLPG | GALAPAGOS NV | 2,224,403 | $123M | 3.9% | $53.36 | — | SPON ADR | 36315X101 |
| NUVB | NUVATION BIO INC | 13,896,543 | $118M | 3.8% | $11.16 | -17.7% | COM CL A | 67080N101 |
| ALEC | ALECTOR INC | 4,994,970 | $103M | 3.3% | $20.12 | +12.1% | COM | 014442107 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 2,639,706 | $90.28M | 2.9% | $37.64 | -16.0% | COM | 74366E102 |
| CRSP | CRISPR THERAPEUTICS AG | 1,077,483 | $81.65M | 2.6% | $87.36 | 0.0% | NAMEN AKT | H17182108 |
| — | GRITSTONE BIO INC | 6,012,232 | $77.32M | 2.5% | $7.05 | — | COM | 39868T105 |
| ACAD | ACADIA PHARMACEUTICALS INC | 3,060,593 | $71.43M | 2.3% | $20.11 | 0.0% | COM | 004225108 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,759,505 | $65.59M | 2.1% | $27.15 | -12.0% | COM | 05370A108 |
| — | ITEOS THERAPEUTICS INC | 1,303,157 | $60.67M | 1.9% | $25.73 | — | COM | 46565G104 |
| RLAY | RELAY THERAPEUTICS INC | 1,779,084 | $54.64M | 1.7% | $35.94 | -12.1% | COM | 75943R102 |
| KURA | KURA ONCOLOGY INC | 3,724,437 | $52.14M | 1.7% | $22.14 | -26.8% | COM | 50127T109 |
| ORIC | ORIC PHARMACEUTICALS INC | 3,468,944 | $50.99M | 1.6% | $30.24 | -48.4% | COM | 68622P109 |
| — | 2SEVENTY BIO ORD | 1,917,063 | $49.13M | 1.6% | $25.63 | — | COMMON STOCK ADDED | 901384107 |
| AVIR | ATEA PHARMACEUTICALS INC | 5,376,134 | $48.06M | 1.5% | $15.58 | 0.0% | COM | 04683R106 |
| DSGN | DESIGN THERAPEUTICS INC | 2,152,997 | $46.1M | 1.5% | $24.86 | -30.9% | COM | 25056L103 |
| — | SAGE THERAPEUTICS INC | 940,636 | $40.02M | 1.3% | $42.54 | — | COM | 78667J108 |
| JANX | JANUX THERAPEUTICS INC | 1,411,975 | $27.86M | 0.9% | $22.27 | -5.9% | COM | 47103J105 |
| — | PARDES BIOSCIENCES ORD | 1,597,139 | $26.14M | 0.8% | $16.37 | — | COM ADDED | 69945Q105 |
| VTYX | VENTYX BIOSCIENCES ORD | 1,300,000 | $25.82M | 0.8% | $18.95 | 0.0% | COM ADDED | 92332V107 |
| EWTX | EDGEWISE THERAPEUTICS INC | 1,279,175 | $19.55M | 0.6% | $31.81 | -43.4% | COM | 28036F105 |
| OVID | OVID THERAPEUTICS INC | 6,082,200 | $19.52M | 0.6% | $3.32 | +3.2% | COM | 690469101 |
| — | AKOUOS INC | 1,975,984 | $16.8M | 0.5% | $22.50 | — | COM | 00973J101 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 590,169 | $16.77M | 0.5% | $24.65 | 0.0% | COM | 22663K107 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 98,146 | $16.64M | 0.5% | $185.86 | 0.0% | COM | 02043Q107 |
| — | SOLID BIOSCIENCES INC | 9,202,702 | $16.11M | 0.5% | $7.31 | — | COM | 83422E105 |
| HALO | HALOZYME THERAPEUTICS INC | 392,000 | $15.76M | 0.5% | $37.33 | 0.0% | COM | 40637H109 |
| LEGN | LEGEND BIOTECH CORP | 307,594 | $14.34M | 0.5% | $46.61 | — | SPONSORED ADS | 52490G102 |
| TNGX | TANGO THERAPEUTICS INC | 1,300,000 | $14.22M | 0.5% | $11.99 | +0.3% | COM | 87583X109 |
| ERAS | ERASCA INC | 700,000 | $10.91M | 0.3% | $20.63 | -17.0% | COM | 29479A108 |
| ARVN | ARVINAS INC | 130,300 | $10.7M | 0.3% | $81.37 | 0.0% | COM | 04335A105 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 882,176 | $9.933M | 0.3% | $20.63 | — | SPONSORED ADS | 152309100 |
| IMVT | IMMUNOVANT INC | 1,140,819 | $9.72M | 0.3% | $9.02 | -8.5% | COM | 45258J102 |
| VYGR | VOYAGER THERAPEUTICS INC | 3,557,507 | $9.641M | 0.3% | $2.70 | — | COM | 92915B106 |
| NRIX | NURIX THERAPEUTICS INC | 309,540 | $8.961M | 0.3% | $29.56 | +2.6% | COM | 67080M103 |
| — | GRAPHITE BIO INC | 688,900 | $8.563M | 0.3% | $12.43 | — | COM | 38870X104 |
| — | NUVATION BIO INC | 963,333 | $8.188M | 0.3% | $10.45 | — | *W EXP 07/07/202 | 67080N119 |
| SPRY | SILVERBACK THERAPEUTICS INC | 1,060,010 | $7.06M | 0.2% | $33.36 | -75.6% | COM | 82835W108 |
| CCCC | C4 THERAPEUTICS INC | 200,000 | $6.44M | 0.2% | $29.00 | +36.4% | COM STK | 12529R107 |
| — | FRAZIER LIFESCIENCES ACQU CO | 587,615 | $5.729M | 0.2% | $9.80 | — | SHS | G3710A105 |
| — | APPLIED MOLECULAR TRANS INC | 400,000 | $5.592M | 0.2% | $13.98 | — | COM | 03824M109 |
| — | KRONOS BIO INC | 387,357 | $5.264M | 0.2% | $29.87 | — | COM | 50107A104 |
| — | JIYA ACQUISITION CORP | 500,000 | $4.885M | 0.2% | $10.30 | — | COM CL A | 47760M102 |
| — | NEOLEUKIN THERAPEUTICS INC | 860,619 | $4.148M | 0.1% | $7.28 | — | COM | 64049K104 |
| — | HEALTH SCIENCES ACQ CORP 2 ORD | 400,000 | $4.032M | 0.1% | $11.00 | — | SHS | G4411D109 |
| — | GRITSTONE BIO INC | 307,000 | $3.948M | 0.1% | $7.05 | — | Call | 39868T105 |
| ACIU | AC IMMUNE SA | 749,585 | $3.71M | 0.1% | $5.79 | +0.3% | SHS | H00263105 |
| — | VERVE THERAPEUTICS INC | 100,000 | $3.687M | 0.1% | $60.25 | — | COM | 92539P101 |
| — | KINNATE BIOPHARMA INC | 175,000 | $3.101M | 0.1% | $25.42 | — | COM | 49705R105 |
| DYN | DYNE THERAPEUTICS INC | 215,000 | $2.556M | 0.1% | $21.96 | -36.0% | COM | 26818M108 |
| MLTX | HELIX ACQUISITION CORP | 200,000 | $1.978M | 0.1% | $11.37 | — | COM CL A | G4444C102 |
| — | 5 01 ACQUISITION CORP | 200,000 | $1.97M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | BCLS ACQUISITION CORP | 200,000 | $1.96M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | EUCRATES BIOMEDICAL ACQU COR | 200,000 | $1.952M | 0.1% | $9.98 | — | SHS | G3141W106 |
| — | ADVERUM BIOTECHNOLOGIES INC | 1,046,700 | $1.842M | 0.1% | $1.76 | — | COM | 00773U108 |
| — | ARYA SCIENCES ACQU CORP IV | 150,000 | $1.487M | 0.0% | $10.47 | — | CL A | G31659108 |
| PMVP | PMV PHARMACEUTICALS INC | 50,000 | $1.155M | 0.0% | $36.80 | -34.3% | COM | 69353Y103 |
| CRBU | CARIBOU BIOSCIENCES INC | 75,000 | $1.132M | 0.0% | $24.45 | -20.4% | COM | 142038108 |
| — | ALIGOS THERAPEUTICS INC | 91,044 | $1.081M | 0.0% | $11.87 | — | COM | 01626L105 |
| — | REPARE THERAPEUTICS INC | 50,000 | $1.055M | 0.0% | $31.02 | — | COM | 760273102 |
| — | TURMERIC ACQUISITION CORP | 100,000 | $982K | 0.0% | $9.77 | — | CL A | G9127T108 |
| — | VTV THERAPEUTICS INC | 834,333 | $830K | 0.0% | $0.99 | — | CL A | 918385105 |
| — | CAREMAX INC | 100,000 | $768K | 0.0% | $12.90 | — | *W EXP 06/08/202 | 14171W111 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 37,593 | $768K | 0.0% | $20.94 | 0.0% | COM | 61225M102 |
| — | BOLT BIOTHERAPEUTICS INC | 150,000 | $735K | 0.0% | $32.91 | — | COM | 097702104 |
| — | EUCRATES BIOMEDICAL ACQU COR | 66,666 | $651K | 0.0% | $9.98 | — | *W EXP 10/23/202 | G3141W122 |
| — | FRAZIER LIFESCIENCES ACQU CO | 66,665 | $650K | 0.0% | $9.77 | — | *W EXP 11/30/202 | G3710A113 |
| PCVX | VAXCYTE INC | 20,800 | $495K | 0.0% | $23.26 | 0.0% | COM | 92243G108 |
| — | OMEGA ALPHA SPAC | 50,000 | $489K | 0.0% | $9.90 | — | CL A | G6749V107 |
| SRZNW | SURROZEN INC | 66,665 | $429K | 0.0% | $7.07 | — | COM | 86889P117 |
| — | TURMERIC ACQUISITION CORP | 33,333 | $327K | 0.0% | $9.78 | — | *W EXP 10/08/202 | G9127T124 |