Location: San Francisco, CA
CIK: 0001587114 · Show all filings
Period: Q1 2022 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $3.197B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | 11,584,280 | $424M | 13.3% | $11.63 | +209.8% | SHS | G72800108 |
| APLS | APELLIS PHARMACEUTICALS INC | 5,183,431 | $263M | 8.2% | $40.43 | +9.2% | COM | 03753U106 |
| GLPG | GALAPAGOS NV | 3,195,624 | $198M | 6.2% | $55.99 | — | SPON ADR | 36315X101 |
| ANAB | ANAPTYSBIO INC | 7,521,024 | $186M | 5.8% | $23.15 | +30.7% | COM | 032724106 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,069,634 | $162M | 5.1% | $76.58 | 0.0% | COM | 803607100 |
| — | MORPHIC HLDG INC | 3,951,566 | $159M | 5.0% | $29.75 | — | COM | 61775R105 |
| ACAD | ACADIA PHARMACEUTICALS INC | 5,991,479 | $145M | 4.5% | $22.11 | +9.4% | COM | 004225108 |
| XNCR | XENCOR INC | 4,968,756 | $133M | 4.1% | $34.06 | -5.3% | COM | 98401F105 |
| KURA | KURA ONCOLOGY INC | 6,638,371 | $107M | 3.3% | $18.76 | -23.0% | COM | 50127T109 |
| RCUS | ARCUS BIOSCIENCES INC | 3,265,101 | $103M | 3.2% | $28.65 | +17.0% | COM | 03969F109 |
| ARVN | ARVINAS INC | 1,503,929 | $101M | 3.2% | $69.30 | -1.7% | COM | 04335A105 |
| ZLAB | ZAI LAB LTD | 2,223,212 | $97.78M | 3.1% | $43.98 | — | ADR | 98887Q104 |
| ALEC | ALECTOR INC | 5,738,448 | $81.77M | 2.6% | $19.56 | -19.2% | COM | 014442107 |
| NUVB | NUVATION BIO INC | 13,896,543 | $73.1M | 2.3% | $11.16 | -49.7% | COM CL A | 67080N101 |
| RLAY | RELAY THERAPEUTICS INC | 2,291,441 | $68.58M | 2.1% | $33.33 | -27.2% | COM | 75943R102 |
| — | REATA PHARMACEUTICALS INC | 1,975,611 | $64.72M | 2.0% | $32.76 | — | CL A | 75615P103 |
| — | 2SEVENTY BIO INC | 3,495,943 | $59.64M | 1.9% | $21.76 | — | COMMON STOCK | 901384107 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,646,260 | $57.64M | 1.8% | $35.01 | — | COM | 15678U128 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,759,505 | $50.97M | 1.6% | $27.15 | -37.4% | COM | 05370A108 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,340,639 | $45.78M | 1.4% | $14.25 | -52.3% | COM | 04683R106 |
| — | MIRATI THERAPEUTICS INC | 500,622 | $41.16M | 1.3% | $82.22 | — | COM | 60468T105 |
| ARGX | ARGENX SE | 125,000 | $39.41M | 1.2% | $315.31 | — | SPONSORED ADR | 04016X101 |
| DSGN | DESIGN THERAPEUTICS INC | 2,371,445 | $38.3M | 1.2% | $23.98 | -36.1% | COM | 25056L103 |
| RVMD | REVOLUTION MEDICINES INC | 1,274,097 | $32.5M | 1.0% | $21.77 | 0.0% | COM | 76155X100 |
| PCVX | VAXCYTE INC | 1,304,741 | $31.51M | 1.0% | $21.87 | -0.1% | COM | 92243G108 |
| VYGR | VOYAGER THERAPEUTICS INC | 3,557,507 | $27.11M | 0.8% | $2.70 | — | COM | 92915B106 |
| BCYC | BICYCLE THERAPEUTICS PLC | 547,453 | $24.02M | 0.8% | $43.88 | — | SPONSORED ADS | 088786108 |
| EWTX | EDGEWISE THERAPEUTICS INC | 2,359,808 | $22.89M | 0.7% | $23.14 | -44.4% | COM | 28036F105 |
| EXEL | EXELIXIS INC | 951,333 | $21.57M | 0.7% | $19.53 | 0.0% | COM | 30161Q104 |
| JANX | JANUX THERAPEUTICS INC | 1,421,319 | $20.38M | 0.6% | $22.27 | -26.5% | COM | 47103J105 |
| GERN | GERON CORP | 14,285,714 | $19.43M | 0.6% | $1.11 | 0.0% | COM | 374163103 |
| OVID | OVID THERAPEUTICS INC | 6,117,400 | $19.21M | 0.6% | $3.32 | -5.3% | COM | 690469101 |
| — | SPRINGWORKS THERAPEUTICS INC | 325,881 | $18.39M | 0.6% | $56.44 | — | COM | 85205L107 |
| ORIC | ORIC PHARMACEUTICALS INC | 3,418,068 | $18.25M | 0.6% | $30.24 | -70.2% | COM | 68622P109 |
| VTYX | VENTYX BIOSCIENCES INC | 1,300,000 | $17.64M | 0.6% | $18.95 | -29.5% | COM | 92332V107 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 790,209 | $17.34M | 0.5% | $23.54 | -14.0% | COM | 22663K107 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 895,503 | $17.25M | 0.5% | $16.92 | 0.0% | COM | 03969K108 |
| — | SURFACE ONCOLOGY INC | 4,653,000 | $13.68M | 0.4% | $2.94 | — | COM | 86877M209 |
| PMVP | PMV PHARMACEUTICALS INC | 649,786 | $13.53M | 0.4% | $19.11 | -7.7% | COM | 69353Y103 |
| — | HOOKIPA PHARMA INC | 5,000,000 | $11.4M | 0.4% | $2.28 | — | COM | 43906K100 |
| — | CHINOOK THERAPEUTICS INC | 690,000 | $11.29M | 0.4% | $16.36 | — | COM | 16961L106 |
| — | AKOUOS INC | 1,975,984 | $9.386M | 0.3% | $22.50 | — | COM | 00973J101 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 381,711 | $9.039M | 0.3% | $37.64 | -25.1% | COM | 74366E102 |
| — | ALIGOS THERAPEUTICS INC | 3,948,360 | $8.489M | 0.3% | $2.37 | — | COM | 01626L105 |
| — | NGM BIOPHARMACEUTICALS INC | 541,108 | $8.252M | 0.3% | $15.25 | — | COM | 62921N105 |
| — | IGM BIOSCIENCES INC | 298,597 | $7.981M | 0.2% | $26.73 | — | COM | 449585108 |
| ERAS | ERASCA INC | 678,441 | $5.835M | 0.2% | $20.63 | -43.8% | COM | 29479A108 |
| TNGX | TANGO THERAPEUTICS INC | 761,971 | $5.776M | 0.2% | $11.99 | -27.7% | COM | 87583X109 |
| — | FRAZIER LIFESCIENCES ACQU CO CL A | 587,615 | $5.776M | 0.2% | $9.80 | — | SHS | G3710A105 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 115,236 | $5.317M | 0.2% | $53.94 | 0.0% | COM | 98943L107 |
| — | GRAPHITE BIO INC | 1,024,279 | $5.224M | 0.2% | $10.03 | — | COM | 38870X104 |
| — | NUVATION BIO INC | 963,333 | $5.067M | 0.2% | $10.45 | — | *W EXP 07/07/202 | 67080N119 |
| — | JIYA ACQUISITION CORP | 500,000 | $4.915M | 0.2% | $10.30 | — | COM CL A | 47760M102 |
| CCCC | C4 THERAPEUTICS INC | 200,000 | $4.852M | 0.2% | $29.00 | -16.3% | COM STK | 12529R107 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 454,545 | $4.077M | 0.1% | $20.63 | — | SPONSORED ADS | 152309100 |
| — | HEALTH SCIENCES ACQ CORP 2 ORD | 400,000 | $3.964M | 0.1% | $11.00 | — | SHS | G4411D109 |
| — | GRACELL BIOTECHNOLOGIES INC | 1,559,710 | $3.634M | 0.1% | $2.33 | — | SPONSORED ADS | 38406L103 |
| NRIX | NURIX THERAPEUTICS INC | 254,473 | $3.565M | 0.1% | $29.56 | -39.9% | COM | 67080M103 |
| — | SOLID BIOSCIENCES INC | 2,565,102 | $3.078M | 0.1% | $7.31 | — | COM | 83422E105 |
| — | KRONOS BIO INC | 326,780 | $2.363M | 0.1% | $29.87 | — | COM | 50107A104 |
| — | ITEOS THERAPEUTICS INC | 72,821 | $2.343M | 0.1% | $25.73 | — | COM | 46565G104 |
| — | VERVE THERAPEUTICS INC | 98,593 | $2.25M | 0.1% | $60.25 | — | COM | 92539P101 |
| MLTX | HELIX ACQUISITION CORP | 200,000 | $2.22M | 0.1% | $11.37 | — | COM CL A | G4444C102 |
| DYN | DYNE THERAPEUTICS INC | 215,000 | $2.073M | 0.1% | $21.96 | -61.2% | COM | 26818M108 |
| — | BCLS ACQUISITION CORP | 200,000 | $1.974M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | KINNATE BIOPHARMA INC | 175,000 | $1.971M | 0.1% | $25.42 | — | COM | 49705R105 |
| — | 5 01 ACQUISITION CORP | 200,000 | $1.97M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | EUCRATES BIOMEDICAL ACQU COR | 200,000 | $1.968M | 0.1% | $9.98 | — | SHS | G3141W106 |
| ACIU | AC IMMUNE SA | 485,005 | $1.94M | 0.1% | $5.79 | -25.3% | SHS | H00263105 |
| — | ARYA SCIENCES ACQU CORP IV | 150,000 | $1.47M | 0.0% | $10.47 | — | CL A | G31659108 |
| — | PARDES BIOSCIENCES INC | 200,000 | $1.394M | 0.0% | $16.37 | — | COM | 69945Q105 |
| — | ADVERUM BIOTECHNOLOGIES INC | 1,046,700 | $1.371M | 0.0% | $1.76 | — | COM | 00773U108 |
| — | MERSANA THERAPEUTICS INC | 326,578 | $1.303M | 0.0% | $3.99 | — | COM | 59045L106 |
| SPRY | SILVERBACK THERAPEUTICS INC | 329,537 | $1.157M | 0.0% | $33.36 | -86.9% | COM | 82835W108 |
| — | ATRECA INC | 358,780 | $1.137M | 0.0% | $3.17 | — | CL A COM | 04965G109 |
| — | APPLIED MOLECULAR TRANS INC | 131,693 | $990K | 0.0% | $13.98 | — | COM | 03824M109 |
| — | TURMERIC ACQUISITION CORP | 100,000 | $985K | 0.0% | $9.77 | — | CL A | G9127T108 |
| — | CAREMAX INC | 100,000 | $747K | 0.0% | $12.90 | — | *W EXP 06/08/202 | 14171W111 |
| — | REPARE THERAPEUTICS INC | 50,000 | $712K | 0.0% | $31.02 | — | COM | 760273102 |
| CRBU | CARIBOU BIOSCIENCES INC | 75,000 | $689K | 0.0% | $24.45 | -56.9% | COM | 142038108 |
| — | EUCRATES BIOMEDICAL ACQU COR | 66,666 | $656K | 0.0% | $9.98 | — | Call | G3141W122 |
| — | FRAZIER LIFESCIENCES ACQU CO | 66,665 | $655K | 0.0% | $9.77 | — | *W EXP 11/30/202 | G3710A113 |
| — | OMEGA ALPHA SPAC | 50,000 | $491K | 0.0% | $9.90 | — | CL A | G6749V107 |
| — | BOLT BIOTHERAPEUTICS INC | 150,000 | $411K | 0.0% | $32.91 | — | COM | 097702104 |
| — | TURMERIC ACQUISITION CORP | 33,333 | $328K | 0.0% | $9.78 | — | *W EXP 10/08/202 | G9127T124 |
| — | RADIUS HEALTH INC | 35,000 | $309K | 0.0% | $8.83 | — | COM NEW | 750469207 |
| SRZNW | SURROZEN INC | 66,665 | $201K | 0.0% | $7.07 | — | *W EXP 08/01/203 | 86889P117 |