PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 15, 2025

Total Value: $1.377B (97.3% shares, 2.7% debt)

Holdings (66)

LLY ELI LILLY & CO 16.4%
Value $226M Shares 273,778 Share Price $825.91 Est. Cost/Share $156.24 Unrealized @ Report Date +429.1%
ABBV ABBVIE INC 5.0%
Value $69.51M Shares 331,741 Share Price $209.52 * Est. Cost/Share $133.14 Unrealized @ Report Date +42.3%
THC TENET HEALTHCARE CORP 4.8%
Value $66.08M Shares 491,334 Share Price $134.50 * Est. Cost/Share $51.38 Unrealized @ Report Date +156.3%
MCK MCKESSON CORP 4.8%
Value $65.62M Shares 97,498 Share Price $672.99 * Est. Cost/Share $163.53 Unrealized @ Report Date +276.6%
AXSM AXSOME THERAPEUTICS INC 4.7%
Value $64.91M Shares 556,545 Share Price $116.63 * Est. Cost/Share $49.35 Unrealized @ Report Date +130.9%
XLV SELECT SECTOR SPDR TR 4.6%
Value $62.74M Shares 429,700 Share Price $146.01 Est. Cost/Share $137.57 Unrealized @ Report Date —
VRTX VERTEX PHARMACEUTICALS INC 4.5%
Value $61.57M Shares 126,989 Share Price $484.82 * Est. Cost/Share $369.42 Unrealized @ Report Date +26.1%
ISRG INTUITIVE SURGICAL INC 3.3%
Value $46.1M Shares 93,073 Share Price $495.27 * Est. Cost/Share $358.21 Unrealized @ Report Date +54.4%
PEN PENUMBRA INC 3.2%
Value $44.46M Shares 166,261 Share Price $267.41 Est. Cost/Share $192.69 Unrealized @ Report Date +40.4%
SLNO SOLENO THERAPEUTICS INC 3.1%
Value $42.53M Shares 595,206 Share Price $71.45 * Est. Cost/Share $50.31 Unrealized @ Report Date -3.2%
ARGX ARGENX SE 3.0%
Value $40.84M Shares 68,999 Share Price $591.86 Est. Cost/Share $395.24 Unrealized @ Report Date —
ELV ELEVANCE HEALTH INC 2.8%
Value $38.37M Shares 88,222 Share Price $434.96 * Est. Cost/Share $394.28 Unrealized @ Report Date 0.0%
BBIO BRIDGEBIO PHARMA INC 2.3%
Value $31.39M Shares 908,135 Share Price $34.57 * Est. Cost/Share $31.20 Unrealized @ Report Date +8.1%
UHS UNIVERSAL HLTH SVCS INC 2.1%
Value $29.22M Shares 155,520 Share Price $187.90 * Est. Cost/Share $132.63 Unrealized @ Report Date +37.0%
ASND ASCENDIS PHARMA A/S 2.1%
Value $29.13M Shares 186,916 Share Price $155.86 Est. Cost/Share $154.02 Unrealized @ Report Date —
EW EDWARDS LIFESCIENCES CORP 2.0%
Value $27.54M Shares 379,954 Share Price $72.48 Est. Cost/Share $74.28 Unrealized @ Report Date -3.6%
— ASCENDIS PHARMA A/S 2.0%
Value $27.34M Shares 23,000,000 Share Price $1.19 Est. Cost/Share $1.14 Unrealized @ Report Date —
HCA HCA HEALTHCARE INC 1.9%
Value $26.77M Shares 77,464 Share Price $345.55 * Est. Cost/Share $229.48 Unrealized @ Report Date +39.2%
ALNY ALNYLAM PHARMACEUTICALS INC 1.7%
Value $23.53M Shares 87,145 Share Price $270.02 * Est. Cost/Share $257.00 Unrealized @ Report Date 0.0%
MOH MOLINA HEALTHCARE INC 1.7%
Value $23.09M Shares 70,088 Share Price $329.39 * Est. Cost/Share $221.27 Unrealized @ Report Date +36.5%
DHR DANAHER CORPORATION 1.7%
Value $23.06M Shares 112,475 Share Price $205.00 * Est. Cost/Share $143.93 Unrealized @ Report Date +50.8%
CVS CVS HEALTH CORP 1.5%
Value $21.16M Shares 312,305 Share Price $67.75 * Est. Cost/Share $57.99 Unrealized @ Report Date 0.0%
BDX BECTON DICKINSON & CO 1.5%
Value $20.98M Shares 91,571 Share Price $229.06 Est. Cost/Share $227.37 Unrealized @ Report Date 0.0%
IQV IQVIA HLDGS INC 1.4%
Value $19.72M Shares 111,854 Share Price $176.30 * Est. Cost/Share $144.71 Unrealized @ Report Date +34.1%
WAT WATERS CORP 1.4%
Value $19.11M Shares 51,858 Share Price $368.57 * Est. Cost/Share $332.10 Unrealized @ Report Date +16.6%
UNH UNITEDHEALTH GROUP INC 1.4%
Value $18.8M Shares 35,904 Share Price $523.75 * Est. Cost/Share $439.75 Unrealized @ Report Date +13.6%
OM OUTSET MED INC 1.4%
Value $18.64M Shares 1,685,727 Share Price $11.06 * Est. Cost/Share $11.92 Unrealized @ Report Date 0.0%
HUM HUMANA INC 1.2%
Value $16.73M Shares 63,238 Share Price $264.60 Est. Cost/Share $349.66 Unrealized @ Report Date -23.7%
SNDX SYNDAX PHARMACEUTICALS INC 0.8%
Value $11.38M Shares 926,424 Share Price $12.29 * Est. Cost/Share $15.77 Unrealized @ Report Date -10.6%
OSCR OSCAR HEALTH INC 0.8%
Value $11.29M Shares 860,821 Share Price $13.11 * Est. Cost/Share $11.23 Unrealized @ Report Date +32.2%
— INDIVIOR PLC 0.8%
Value $11.05M Shares 1,159,833 Share Price $9.53 Est. Cost/Share $9.53 Unrealized @ Report Date —
AZN ASTRAZENECA PLC 0.8%
Value $11.04M Shares 150,200 Share Price $73.50 Est. Cost/Share $73.50 Unrealized @ Report Date —
TMO THERMO FISHER SCIENTIFIC INC 0.8%
Value $10.9M Shares 21,897 Share Price $497.60 * Est. Cost/Share $517.29 Unrealized @ Report Date +4.3%
XRT SPDR SER TR 0.8%
Value $10.86M Shares 157,200 Share Price $69.09 Est. Cost/Share $69.09 Unrealized @ Report Date —
— SAREPTA THERAPEUTICS INC 0.7%
Value $9.31M Shares 10,000,000 Share Price $0.93 Est. Cost/Share $1.21 Unrealized @ Report Date —
CNC CENTENE CORP DEL 0.6%
Value $8.22M Shares 135,398 Share Price $60.71 Est. Cost/Share $62.36 Unrealized @ Report Date -3.1%
CNTA CENTESSA PHARMACEUTICALS PLC 0.6%
Value $8.204M Shares 570,546 Share Price $14.38 Est. Cost/Share $12.81 Unrealized @ Report Date —
ICLR ICON PLC 0.5%
Value $7.181M Shares 41,038 Share Price $174.99 * Est. Cost/Share $218.41 Unrealized @ Report Date -11.2%
QURE UNIQURE NV 0.5%
Value $6.36M Shares 599,967 Share Price $10.60 * Est. Cost/Share $10.89 Unrealized @ Report Date +28.7%
INBX INHIBRX BIOSCIENCES INC 0.4%
Value $6.146M Shares 439,283 Share Price $13.99 * Est. Cost/Share $14.21 Unrealized @ Report Date -4.4%
PRAX PRAXIS PRECISION MEDICINES I 0.4%
Value $6.092M Shares 160,866 Share Price $37.87 * Est. Cost/Share $29.44 Unrealized @ Report Date +112.2%
NEO NEOGENOMICS INC 0.4%
Value $5.555M Shares 585,381 Share Price $9.49 * Est. Cost/Share $12.49 Unrealized @ Report Date 0.0%
ERAS ERASCA INC 0.3%
Value $4.781M Shares 3,489,559 Share Price $1.37 * Est. Cost/Share $9.44 Unrealized @ Report Date -81.8%
BHVN BIOHAVEN LTD 0.3%
Value $4.743M Shares 197,307 Share Price $24.04 * Est. Cost/Share $46.66 Unrealized @ Report Date -24.4%
— BLUEPRINT MEDICINES CORP 0.3%
Value $4.112M Shares 46,453 Share Price $88.51 Est. Cost/Share $87.32 Unrealized @ Report Date —
PMVP PMV PHARMACEUTICALS INC 0.3%
Value $3.599M Shares 3,301,942 Share Price $1.09 * Est. Cost/Share $3.94 Unrealized @ Report Date -65.5%
SRPT SAREPTA THERAPEUTICS INC 0.2%
Value $3.243M Shares 50,809 Share Price $63.82 * Est. Cost/Share $127.08 Unrealized @ Report Date -17.2%
XENE XENON PHARMACEUTICALS INC 0.2%
Value $3.095M Shares 92,236 Share Price $33.55 * Est. Cost/Share $36.66 Unrealized @ Report Date +3.6%
AMLX AMYLYX PHARMACEUTICALS INC 0.2%
Value $2.953M Shares 834,135 Share Price $3.54 Est. Cost/Share $3.56 Unrealized @ Report Date 0.0%
IOBT IO BIOTECH INC 0.2%
Value $2.552M Shares 2,341,107 Share Price $1.09 * Est. Cost/Share $2.96 Unrealized @ Report Date -68.1%
XRT SPDR SER TR 0.2%
Value $2.52M Shares 36,471 Share Price $69.09 Est. Cost/Share $69.09 Unrealized @ Report Date —
HOWL WEREWOLF THERAPEUTICS INC 0.2%
Value $2.437M Shares 2,506,520 Share Price $0.97 * Est. Cost/Share $4.07 Unrealized @ Report Date -67.8%
CRBU CARIBOU BIOSCIENCES INC 0.2%
Value $2.289M Shares 2,506,435 Share Price $0.91 * Est. Cost/Share $14.05 Unrealized @ Report Date -90.8%
SGMT SAGIMET BIOSCIENCES INC 0.2%
Value $2.116M Shares 649,006 Share Price $3.26 * Est. Cost/Share $12.35 Unrealized @ Report Date -66.0%
CAPR CAPRICOR THERAPEUTICS INC 0.1%
Value $1.335M Shares 140,681 Share Price $9.49 * Est. Cost/Share $10.43 Unrealized @ Report Date +33.1%
CMPS COMPASS PATHWAYS PLC 0.1%
Value $1.291M Shares 451,267 Share Price $2.86 Est. Cost/Share $8.52 Unrealized @ Report Date —
MGX METAGENOMI INC 0.1%
Value $1.205M Shares 885,803 Share Price $1.36 * Est. Cost/Share $11.50 Unrealized @ Report Date -79.3%
— SPRINGWORKS THERAPEUTICS INC 0.1%
Value $1.167M Shares 26,437 Share Price $44.13 Est. Cost/Share $44.13 Unrealized @ Report Date —
KROS KEROS THERAPEUTICS INC 0.1%
Value $1.063M Shares 104,323 Share Price $10.19 * Est. Cost/Share $50.86 Unrealized @ Report Date -77.2%
ACLX ARCELLX INC 0.1%
Value $1.016M Shares 15,488 Share Price $65.60 * Est. Cost/Share $29.92 Unrealized @ Report Date +126.4%
— VERVE THERAPEUTICS INC 0.1%
Value $711K Shares 155,495 Share Price $4.57 Est. Cost/Share $4.79 Unrealized @ Report Date —
GPCR STRUCTURE THERAPEUTICS INC 0.1%
Value $699K Shares 40,400 Share Price $17.31 Est. Cost/Share $17.31 Unrealized @ Report Date —
CELC CELCUITY INC 0.0%
Value $539K Shares 53,349 Share Price $10.11 * Est. Cost/Share $15.17 Unrealized @ Report Date -25.4%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.0%
Value $440K Shares 132,152 Share Price $3.33 * Est. Cost/Share $11.64 Unrealized @ Report Date -55.7%
— TURNSTONE BIOLOGICS CORP 0.0%
Value $382K Shares 932,348 Share Price $0.41 Est. Cost/Share $3.52 Unrealized @ Report Date —
BOLD BOUNDLESS BIO INC 0.0%
Value $363K Shares 240,513 Share Price $1.51 * Est. Cost/Share $9.83 Unrealized @ Report Date -78.9%