PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value: $1.614B (97.9% shares, 2.1% debt)

Holdings (83)

LLY ELI LILLY & CO 14.3%
Value $231M Shares 298,643 Share Price $772.00 * Est. Cost/Share $156.24 Unrealized @ Report Date +425.6%
IEF ISHARES TR 5.7%
Value $92.45M Shares 1,000,000 Share Price $92.45 Est. Cost/Share — Unrealized @ Report Date —
XLV SELECT SECTOR SPDR TR 4.0%
Value $63.93M Shares 464,700 Share Price $137.57 Est. Cost/Share $137.57 Unrealized @ Report Date —
THC TENET HEALTHCARE CORP 3.8%
Value $62.02M Shares 491,334 Share Price $126.23 * Est. Cost/Share $51.38 Unrealized @ Report Date +189.4%
ABBV ABBVIE INC 3.7%
Value $58.95M Shares 331,741 Share Price $177.70 Est. Cost/Share $133.14 Unrealized @ Report Date +33.3%
MCK MCKESSON CORP 3.4%
Value $55.57M Shares 97,498 Share Price $569.91 * Est. Cost/Share $163.53 Unrealized @ Report Date +240.8%
VRTX VERTEX PHARMACEUTICALS INC 3.2%
Value $51.14M Shares 126,989 Share Price $402.70 * Est. Cost/Share $369.42 Unrealized @ Report Date +25.5%
ISRG INTUITIVE SURGICAL INC 3.0%
Value $48.58M Shares 93,073 Share Price $521.96 Est. Cost/Share $358.21 Unrealized @ Report Date +45.4%
EW EDWARDS LIFESCIENCES CORP 2.7%
Value $43.99M Shares 594,172 Share Price $74.03 * Est. Cost/Share $74.28 Unrealized @ Report Date -5.8%
AXSM AXSOME THERAPEUTICS INC 2.5%
Value $39.55M Shares 467,427 Share Price $84.61 * Est. Cost/Share $37.03 Unrealized @ Report Date +148.3%
PEN PENUMBRA INC 2.4%
Value $39.48M Shares 166,261 Share Price $237.48 * Est. Cost/Share $192.69 Unrealized @ Report Date +18.0%
ARGX ARGENX SE 2.4%
Value $39.17M Shares 63,699 Share Price $615.00 Est. Cost/Share $378.88 Unrealized @ Report Date —
EW EDWARDS LIFESCIENCES CORP 2.4%
Value $38.9M Shares 525,400 Share Price $74.03 * Est. Cost/Share $74.28 Unrealized @ Report Date -5.8%
UHS UNIVERSAL HLTH SVCS INC 2.4%
Value $38.39M Shares 213,983 Share Price $179.42 * Est. Cost/Share $132.63 Unrealized @ Report Date +52.8%
UNH UNITEDHEALTH GROUP INC 2.4%
Value $38.24M Shares 75,588 Share Price $505.86 * Est. Cost/Share $439.75 Unrealized @ Report Date +25.7%
UNH UNITEDHEALTH GROUP INC 1.8%
Value $28.99M Shares 57,300 Share Price $505.86 * Est. Cost/Share $439.75 Unrealized @ Report Date +25.7%
DHR DANAHER CORPORATION 1.8%
Value $28.81M Shares 125,515 Share Price $229.55 * Est. Cost/Share $143.93 Unrealized @ Report Date +69.5%
NVO NOVO-NORDISK A S 1.8%
Value $28.81M Shares 334,900 Share Price $86.02 Est. Cost/Share — Unrealized @ Report Date —
ICLR ICON PLC 1.7%
Value $26.98M Shares 128,637 Share Price $209.71 * Est. Cost/Share $218.41 Unrealized @ Report Date +6.9%
DXCM DEXCOM INC 1.6%
Value $25.57M Shares 328,763 Share Price $77.77 * Est. Cost/Share $74.04 Unrealized @ Report Date 0.0%
— ASCENDIS PHARMA A/S 1.6%
Value $25.33M Shares 23,000,000 Share Price $1.10 Est. Cost/Share $1.14 Unrealized @ Report Date —
NBIX NEUROCRINE BIOSCIENCES INC 1.4%
Value $22.77M Shares 166,803 Share Price $136.50 * Est. Cost/Share $123.68 Unrealized @ Report Date 0.0%
IQV IQVIA HLDGS INC 1.4%
Value $21.98M Shares 111,854 Share Price $196.51 * Est. Cost/Share $144.71 Unrealized @ Report Date +45.7%
WAT WATERS CORP 1.4%
Value $21.91M Shares 59,053 Share Price $370.98 Est. Cost/Share $332.10 Unrealized @ Report Date +10.1%
IJH ISHARES TR 1.3%
Value $21.66M Shares 347,637 Share Price $62.31 Est. Cost/Share $62.31 Unrealized @ Report Date —
HUM HUMANA INC 1.3%
Value $21.07M Shares 83,037 Share Price $253.71 * Est. Cost/Share $349.66 Unrealized @ Report Date -24.6%
HCA HCA HEALTHCARE INC 1.3%
Value $20.84M Shares 69,441 Share Price $300.15 * Est. Cost/Share $219.09 Unrealized @ Report Date +58.0%
MOH MOLINA HEALTHCARE INC 1.3%
Value $20.4M Shares 70,088 Share Price $291.05 * Est. Cost/Share $221.27 Unrealized @ Report Date +39.6%
RSP INVESCO EXCHANGE TRADED FD T 1.2%
Value $18.93M Shares 108,041 Share Price $175.23 Est. Cost/Share $175.23 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP DEL 1.1%
Value $18.52M Shares 52,500 Share Price $352.84 * Est. Cost/Share $367.56 Unrealized @ Report Date 0.0%
CAH CARDINAL HEALTH INC 1.1%
Value $17.52M Shares 148,173 Share Price $118.27 * Est. Cost/Share $114.81 Unrealized @ Report Date 0.0%
BHVN BIOHAVEN LTD 1.0%
Value $16.13M Shares 431,916 Share Price $37.35 * Est. Cost/Share $46.66 Unrealized @ Report Date 0.0%
XBI SPDR SER TR 1.0%
Value $16.13M Shares 179,100 Share Price $90.06 Est. Cost/Share $98.80 Unrealized @ Report Date —
SLNO SOLENO THERAPEUTICS INC 0.9%
Value $13.82M Shares 307,503 Share Price $44.95 * Est. Cost/Share $51.81 Unrealized @ Report Date 0.0%
KWEB KRANESHARES TRUST 0.8%
Value $12.71M Shares 434,700 Share Price $29.24 Est. Cost/Share $29.24 Unrealized @ Report Date —
SRPT SAREPTA THERAPEUTICS INC 0.8%
Value $12.18M Shares 100,172 Share Price $121.59 Est. Cost/Share $127.08 Unrealized @ Report Date -3.6%
IWM ISHARES TR 0.8%
Value $12.11M Shares 54,800 Share Price $220.96 Est. Cost/Share — Unrealized @ Report Date —
SYK STRYKER CORPORATION 0.7%
Value $11.65M Shares 32,349 Share Price $360.05 Est. Cost/Share $305.79 Unrealized @ Report Date +19.8%
VEEV VEEVA SYS INC 0.7%
Value $11.64M Shares 55,383 Share Price $210.25 * Est. Cost/Share $212.18 Unrealized @ Report Date +3.6%
OSCR OSCAR HEALTH INC 0.7%
Value $11.57M Shares 860,821 Share Price $13.44 * Est. Cost/Share $11.23 Unrealized @ Report Date +43.4%
XLV SELECT SECTOR SPDR TR 0.7%
Value $11.53M Shares 83,806 Share Price $137.57 Est. Cost/Share $137.57 Unrealized @ Report Date —
ERAS ERASCA INC 0.7%
Value $11.02M Shares 4,390,427 Share Price $2.51 * Est. Cost/Share $9.44 Unrealized @ Report Date -71.0%
TMO THERMO FISHER SCIENTIFIC INC 0.7%
Value $10.95M Shares 21,040 Share Price $520.23 * Est. Cost/Share $516.37 Unrealized @ Report Date +6.0%
PRAX PRAXIS PRECISION MEDICINES I 0.6%
Value $9.197M Shares 119,509 Share Price $76.96 * Est. Cost/Share $18.01 Unrealized @ Report Date +301.8%
CNC CENTENE CORP DEL 0.5%
Value $8.754M Shares 144,501 Share Price $60.58 * Est. Cost/Share $62.36 Unrealized @ Report Date 0.0%
TEVA TEVA PHARMACEUTICAL INDS LTD 0.5%
Value $8.75M Shares 397,024 Share Price $22.04 Est. Cost/Share $22.04 Unrealized @ Report Date —
— SAREPTA THERAPEUTICS INC 0.5%
Value $8.529M Shares 7,750,000 Share Price $1.10 Est. Cost/Share $1.29 Unrealized @ Report Date —
BBIO BRIDGEBIO PHARMA INC 0.5%
Value $7.964M Shares 290,242 Share Price $27.44 * Est. Cost/Share $25.84 Unrealized @ Report Date 0.0%
SPY SPDR S&P 500 ETF TR 0.5%
Value $7.283M Shares 12,427 Share Price $586.08 Est. Cost/Share $586.08 Unrealized @ Report Date —
ASND ASCENDIS PHARMA A/S 0.4%
Value $7.213M Shares 52,392 Share Price $137.67 Est. Cost/Share $149.31 Unrealized @ Report Date —
CNTA CENTESSA PHARMACEUTICALS PLC 0.4%
Value $6.227M Shares 371,766 Share Price $16.75 Est. Cost/Share $11.97 Unrealized @ Report Date —
CRBU CARIBOU BIOSCIENCES INC 0.4%
Value $6.164M Shares 3,876,462 Share Price $1.59 * Est. Cost/Share $14.05 Unrealized @ Report Date -85.7%
— SPRINGWORKS THERAPEUTICS INC 0.3%
Value $5.42M Shares 150,000 Share Price $36.13 Est. Cost/Share — Unrealized @ Report Date —
KWEB KRANESHARES TRUST 0.3%
Value $5.292M Shares 180,974 Share Price $29.24 Est. Cost/Share $29.24 Unrealized @ Report Date —
QURE UNIQURE NV 0.3%
Value $5.001M Shares 283,158 Share Price $17.66 * Est. Cost/Share $7.39 Unrealized @ Report Date +16.8%
XENE XENON PHARMACEUTICALS INC 0.3%
Value $4.586M Shares 116,998 Share Price $39.20 * Est. Cost/Share $36.66 Unrealized @ Report Date +12.8%
ACLX ARCELLX INC 0.3%
Value $4.341M Shares 56,603 Share Price $76.69 * Est. Cost/Share $29.92 Unrealized @ Report Date +188.7%
HOWL WEREWOLF THERAPEUTICS INC 0.3%
Value $4.3M Shares 2,905,465 Share Price $1.48 * Est. Cost/Share $4.07 Unrealized @ Report Date -49.9%
BNTX BIONTECH SE 0.2%
Value $3.773M Shares 33,109 Share Price $113.95 Est. Cost/Share $113.95 Unrealized @ Report Date —
— BLUEPRINT MEDICINES CORP 0.2%
Value $3.737M Shares 42,840 Share Price $87.22 Est. Cost/Share $87.22 Unrealized @ Report Date —
— INTRA-CELLULAR THERAPIES INC 0.2%
Value $3.392M Shares 40,610 Share Price $83.52 Est. Cost/Share $68.90 Unrealized @ Report Date —
MGX METAGENOMI INC 0.2%
Value $3.198M Shares 885,803 Share Price $3.61 * Est. Cost/Share $11.50 Unrealized @ Report Date -79.0%
PMVP PMV PHARMACEUTICALS INC 0.2%
Value $3.14M Shares 2,079,245 Share Price $1.51 * Est. Cost/Share $5.46 Unrealized @ Report Date -71.0%
INSM INSMED INC 0.2%
Value $3.022M Shares 43,774 Share Price $69.04 * Est. Cost/Share $38.78 Unrealized @ Report Date +85.7%
TGTX TG THERAPEUTICS INC 0.2%
Value $2.97M Shares 98,674 Share Price $30.10 * Est. Cost/Share $21.84 Unrealized @ Report Date +31.4%
SGMT SAGIMET BIOSCIENCES INC 0.2%
Value $2.921M Shares 649,006 Share Price $4.50 * Est. Cost/Share $12.35 Unrealized @ Report Date -59.0%
SNDX SYNDAX PHARMACEUTICALS INC 0.2%
Value $2.735M Shares 206,871 Share Price $13.22 * Est. Cost/Share $21.56 Unrealized @ Report Date -20.6%
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.2%
Value $2.625M Shares 4,871,969 Share Price $0.54 Est. Cost/Share $1.72 Unrealized @ Report Date —
ALKS ALKERMES PLC 0.1%
Value $2.321M Shares 80,719 Share Price $28.76 Est. Cost/Share $28.40 Unrealized @ Report Date +1.2%
JAZZ JAZZ PHARMACEUTICALS PLC 0.1%
Value $2.167M Shares 17,597 Share Price $123.15 * Est. Cost/Share $117.86 Unrealized @ Report Date 0.0%
IOBT IO BIOTECH INC 0.1%
Value $2.154M Shares 2,341,107 Share Price $0.92 * Est. Cost/Share $2.96 Unrealized @ Report Date -66.4%
INBX INHIBRX BIOSCIENCES INC 0.1%
Value $2.087M Shares 135,546 Share Price $15.40 Est. Cost/Share $15.62 Unrealized @ Report Date -2.5%
CELC CELCUITY INC 0.1%
Value $2.078M Shares 158,746 Share Price $13.09 * Est. Cost/Share $15.17 Unrealized @ Report Date -7.0%
CMPS COMPASS PATHWAYS PLC 0.1%
Value $1.706M Shares 451,267 Share Price $3.78 Est. Cost/Share $8.52 Unrealized @ Report Date —
KROS KEROS THERAPEUTICS INC 0.1%
Value $1.651M Shares 104,323 Share Price $15.83 * Est. Cost/Share $50.86 Unrealized @ Report Date +2.2%
BBIO BRIDGEBIO PHARMA INC 0.1%
Value $1.372M Shares 50,000 Share Price $27.44 * Est. Cost/Share $25.84 Unrealized @ Report Date 0.0%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.1%
Value $978K Shares 132,152 Share Price $7.40 * Est. Cost/Share $11.64 Unrealized @ Report Date -20.4%
— GENERATION BIO CO 0.1%
Value $835K Shares 787,914 Share Price $1.06 Est. Cost/Share $6.61 Unrealized @ Report Date —
CAPR CAPRICOR THERAPEUTICS INC 0.0%
Value $750K Shares 54,357 Share Price $13.80 * Est. Cost/Share $4.95 Unrealized @ Report Date +254.3%
— VERVE THERAPEUTICS INC 0.0%
Value $711K Shares 125,999 Share Price $5.64 Est. Cost/Share $4.84 Unrealized @ Report Date —
BOLD BOUNDLESS BIO INC 0.0%
Value $697K Shares 240,513 Share Price $2.90 Est. Cost/Share $9.83 Unrealized @ Report Date -70.4%
— BLUEBIRD BIO INC 0.0%
Value $632K Shares 75,758 Share Price $8.34 Est. Cost/Share $8.34 Unrealized @ Report Date —
— TURNSTONE BIOLOGICS CORP 0.0%
Value $463K Shares 932,348 Share Price $0.50 Est. Cost/Share $3.52 Unrealized @ Report Date —