PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 15, 2021

Total Value: $3.401B (96.5% shares, 3.5% debt)

Holdings (85)

— HORIZON THERAPEUTICS PUB L 5.0%
Value $171M Shares 1,561,290 Share Price $109.54 Est. Cost/Share $64.47 Unrealized @ Report Date —
— OUTSET MED INC 4.3%
Value $147M Shares 2,966,712 Share Price $49.44 Est. Cost/Share $45.84 Unrealized @ Report Date —
LLY LILLY ELI & CO 3.6%
Value $121M Shares 525,455 Share Price $231.05 * Est. Cost/Share $156.24 Unrealized @ Report Date +51.5%
RCUS ARCUS BIOSCIENCES INC 3.5%
Value $120M Shares 3,431,010 Share Price $34.87 * Est. Cost/Share $22.17 Unrealized @ Report Date +40.4%
CYTK CYTOKINETICS INC 3.3%
Value $113M Shares 3,159,701 Share Price $35.74 * Est. Cost/Share $24.28 Unrealized @ Report Date +21.3%
ABBV ABBVIE INC 2.9%
Value $98.86M Shares 916,496 Share Price $107.87 * Est. Cost/Share $72.26 Unrealized @ Report Date +34.5%
ERAS ERASCA INC 2.9%
Value $98.17M Shares 5,191,405 Share Price $18.91 * Est. Cost/Share $20.63 Unrealized @ Report Date 0.0%
HCA HCA HEALTHCARE INC 2.8%
Value $94.78M Shares 390,507 Share Price $242.72 * Est. Cost/Share $114.42 Unrealized @ Report Date +105.7%
MYGN MYRIAD GENETICS INC 2.7%
Value $92.77M Shares 2,872,918 Share Price $32.29 * Est. Cost/Share $28.44 Unrealized @ Report Date +16.8%
CRBU CARIBOU BIOSCIENCES INC 2.6%
Value $88.18M Shares 4,092,309 Share Price $21.55 * Est. Cost/Share $24.45 Unrealized @ Report Date 0.0%
IQV IQVIA HLDGS INC 2.5%
Value $85.73M Shares 357,916 Share Price $239.54 * Est. Cost/Share $142.23 Unrealized @ Report Date +77.5%
AVTR AVANTOR INC 2.5%
Value $85.06M Shares 2,079,657 Share Price $40.90 * Est. Cost/Share $23.15 Unrealized @ Report Date +68.8%
NBIX NEUROCRINE BIOSCIENCES INC 2.4%
Value $82.87M Shares 864,079 Share Price $95.91 Est. Cost/Share $104.37 Unrealized @ Report Date -9.5%
UHS UNIVERSAL HLTH SVCS INC 2.1%
Value $72.06M Shares 520,786 Share Price $138.37 * Est. Cost/Share $123.62 Unrealized @ Report Date +19.6%
MCK MCKESSON CORP 2.0%
Value $69.62M Shares 349,181 Share Price $199.38 * Est. Cost/Share $163.53 Unrealized @ Report Date +19.3%
— GILEAD SCIENCES INC 2.0%
Value $67.31M Shares 963,700 Share Price $69.85 Est. Cost/Share — Unrealized @ Report Date —
— DYNAVAX TECHNOLOGIES CORP 1.9%
Value $63.08M Shares 3,283,570 Share Price $19.21 Est. Cost/Share $7.32 Unrealized @ Report Date —
— SEAGEN INC 1.8%
Value $61.91M Shares 364,630 Share Price $169.80 Est. Cost/Share $157.88 Unrealized @ Report Date —
— UNITEDHEALTH GROUP INC 1.8%
Value $61.42M Shares 157,200 Share Price $390.74 Est. Cost/Share — Unrealized @ Report Date —
CNC CENTENE CORP DEL 1.8%
Value $61.37M Shares 984,871 Share Price $62.31 * Est. Cost/Share $65.65 Unrealized @ Report Date +1.8%
— SELECT SECTOR SPDR TR 1.8%
Value $60.13M Shares 1,602,200 Share Price $37.53 Est. Cost/Share — Unrealized @ Report Date —
EW EDWARDS LIFESCIENCES CORP 1.7%
Value $58.08M Shares 513,005 Share Price $113.21 Est. Cost/Share $66.52 Unrealized @ Report Date +71.6%
UNH UNITEDHEALTH GROUP INC 1.7%
Value $56.77M Shares 145,295 Share Price $390.74 Est. Cost/Share $311.60 Unrealized @ Report Date +23.5%
HUM HUMANA INC 1.6%
Value $54.26M Shares 139,420 Share Price $389.15 * Est. Cost/Share $339.61 Unrealized @ Report Date +19.8%
DHR DANAHER CORPORATION 1.6%
Value $53.49M Shares 175,690 Share Price $304.44 * Est. Cost/Share $143.93 Unrealized @ Report Date +85.4%
— MIRATI THERAPEUTICS INC 1.6%
Value $53.17M Shares 300,545 Share Price $176.91 Est. Cost/Share $168.17 Unrealized @ Report Date —
ICUI ICU MED INC 1.5%
Value $51.48M Shares 220,587 Share Price $233.38 * Est. Cost/Share $183.12 Unrealized @ Report Date +14.5%
— HORIZON THERAPEUTICS PUB L 1.4%
Value $48.13M Shares 439,400 Share Price $109.54 Est. Cost/Share — Unrealized @ Report Date —
— BIOMARIN PHARMACEUTICAL INC 1.4%
Value $47.67M Shares 45,910,000 Share Price $1.04 Est. Cost/Share $1.04 Unrealized @ Report Date —
PEN PENUMBRA INC 1.4%
Value $47.19M Shares 177,088 Share Price $266.50 Est. Cost/Share $227.41 Unrealized @ Report Date +18.2%
AZN ASTRAZENECA PLC 1.4%
Value $47.19M Shares 785,748 Share Price $60.06 Est. Cost/Share $57.66 Unrealized @ Report Date —
GILD GILEAD SCIENCES INC 1.4%
Value $46.56M Shares 666,601 Share Price $69.85 * Est. Cost/Share $53.94 Unrealized @ Report Date +10.1%
— NEVRO CORP 1.3%
Value $45.71M Shares 392,786 Share Price $116.38 Est. Cost/Share $134.81 Unrealized @ Report Date —
THC TENET HEALTHCARE CORP 1.3%
Value $44.32M Shares 667,073 Share Price $66.44 * Est. Cost/Share $29.15 Unrealized @ Report Date +143.3%
— AERIE PHARMACEUTICALS INC 1.3%
Value $44.26M Shares 48,150,000 Share Price $0.92 Est. Cost/Share $0.81 Unrealized @ Report Date —
WAT WATERS CORP 1.2%
Value $42.03M Shares 117,634 Share Price $357.30 * Est. Cost/Share $237.41 Unrealized @ Report Date +65.0%
ICLR ICON PLC 1.2%
Value $41.45M Shares 158,183 Share Price $262.02 * Est. Cost/Share $192.01 Unrealized @ Report Date +26.6%
NVAX NOVAVAX INC 1.2%
Value $40.88M Shares 197,208 Share Price $207.31 * Est. Cost/Share $134.12 Unrealized @ Report Date +64.3%
TMO THERMO FISHER SCIENTIFIC INC 1.2%
Value $40.82M Shares 71,442 Share Price $571.33 * Est. Cost/Share $505.13 Unrealized @ Report Date +7.4%
— BRISTOL-MYERS SQUIBB CO 1.1%
Value $36.21M Shares 612,000 Share Price $59.17 Est. Cost/Share — Unrealized @ Report Date —
SNDX SYNDAX PHARMACEUTICALS INC 1.0%
Value $35.48M Shares 1,856,738 Share Price $19.11 * Est. Cost/Share $21.27 Unrealized @ Report Date -21.7%
SOPH SOPHIA GENETICS SA 1.0%
Value $35.45M Shares 2,022,552 Share Price $17.53 Est. Cost/Share $17.59 Unrealized @ Report Date 0.0%
HRTX HERON THERAPEUTICS INC 0.9%
Value $32M Shares 2,993,546 Share Price $10.69 * Est. Cost/Share $16.85 Unrealized @ Report Date -27.7%
— JOUNCE THERAPEUTICS INC 0.8%
Value $28.6M Shares 3,848,822 Share Price $7.43 Est. Cost/Share $9.84 Unrealized @ Report Date —
— CANO HEALTH INC 0.8%
Value $26.55M Shares 2,094,279 Share Price $12.68 Est. Cost/Share $12.10 Unrealized @ Report Date —
— NEUROCRINE BIOSCIENCES INC 0.7%
Value $25.08M Shares 261,500 Share Price $95.91 Est. Cost/Share — Unrealized @ Report Date —
— AERIE PHARMACEUTICALS INC 0.7%
Value $24.88M Shares 2,182,684 Share Price $11.40 Est. Cost/Share $19.89 Unrealized @ Report Date —
NTLA INTELLIA THERAPEUTICS INC 0.7%
Value $23.91M Shares 178,222 Share Price $134.15 * Est. Cost/Share $67.12 Unrealized @ Report Date +125.6%
— CATALENT INC 0.7%
Value $23.66M Shares 177,800 Share Price $133.07 Est. Cost/Share $133.07 Unrealized @ Report Date —
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.7%
Value $22.77M Shares 4,403,574 Share Price $5.17 Est. Cost/Share $5.53 Unrealized @ Report Date —
— KARUNA THERAPEUTICS INC 0.6%
Value $21.66M Shares 177,091 Share Price $122.33 Est. Cost/Share $119.76 Unrealized @ Report Date —
— IONIS PHARMACEUTICALS INC 0.6%
Value $21.13M Shares 23,000,000 Share Price $0.92 Est. Cost/Share $0.96 Unrealized @ Report Date —
ALLO ALLOGENE THERAPEUTICS INC 0.6%
Value $19.94M Shares 775,819 Share Price $25.70 * Est. Cost/Share $31.44 Unrealized @ Report Date -24.5%
BFLY BUTTERFLY NETWORK INC 0.6%
Value $19.09M Shares 1,828,311 Share Price $10.44 * Est. Cost/Share $19.79 Unrealized @ Report Date -41.7%
MOH MOLINA HEALTHCARE INC 0.6%
Value $19.02M Shares 70,088 Share Price $271.32 * Est. Cost/Share $130.27 Unrealized @ Report Date +102.7%
— IVERIC BIO INC 0.5%
Value $18.48M Shares 1,138,112 Share Price $16.24 Est. Cost/Share $16.24 Unrealized @ Report Date —
STVN STEVANATO GROUP S P A 0.4%
Value $13.89M Shares 549,002 Share Price $25.31 * Est. Cost/Share $23.29 Unrealized @ Report Date 0.0%
SGHT SIGHT SCIENCES INC 0.3%
Value $10.98M Shares 483,538 Share Price $22.70 * Est. Cost/Share $32.87 Unrealized @ Report Date 0.0%
AVIR ATEA PHARMACEUTICALS INC 0.3%
Value $10.61M Shares 302,532 Share Price $35.06 * Est. Cost/Share $27.74 Unrealized @ Report Date 0.0%
GH GUARDANT HEALTH INC 0.3%
Value $10.56M Shares 84,455 Share Price $125.01 * Est. Cost/Share $123.89 Unrealized @ Report Date -4.1%
ZLAB ZAI LAB LTD 0.3%
Value $10.47M Shares 99,375 Share Price $105.39 Est. Cost/Share $135.34 Unrealized @ Report Date —
— DYNAVAX TECHNOLOGIES CORP 0.3%
Value $10.02M Shares 521,800 Share Price $19.21 Est. Cost/Share — Unrealized @ Report Date —
— FS DEVELOPMENT CORP II 0.3%
Value $9.95M Shares 1,000,000 Share Price $9.95 Est. Cost/Share $9.96 Unrealized @ Report Date —
DXCM DEXCOM INC 0.3%
Value $9.576M Shares 17,510 Share Price $546.89 * Est. Cost/Share $126.11 Unrealized @ Report Date 0.0%
PMVP PMV PHARMACEUTICALS INC 0.3%
Value $8.592M Shares 288,334 Share Price $29.80 * Est. Cost/Share $33.40 Unrealized @ Report Date -4.4%
— PRAXIS PRECISION MEDICINES I 0.2%
Value $8.42M Shares 455,374 Share Price $18.49 Est. Cost/Share $18.28 Unrealized @ Report Date —
— HUMANA INC 0.2%
Value $8.172M Shares 21,000 Share Price $389.14 Est. Cost/Share — Unrealized @ Report Date —
— NOVAVAX INC 0.2%
Value $7.354M Shares 4,250,000 Share Price $1.73 Est. Cost/Share $1.26 Unrealized @ Report Date —
HOWL WEREWOLF THERAPEUTICS INC 0.2%
Value $6.864M Shares 400,000 Share Price $17.16 Est. Cost/Share $13.70 Unrealized @ Report Date +24.6%
LAB FLUIDIGM CORP DEL 0.2%
Value $6.462M Shares 980,505 Share Price $6.59 Est. Cost/Share $8.84 Unrealized @ Report Date -25.6%
LFST LIFESTANCE HEALTH GROUP INC 0.2%
Value $6.432M Shares 443,595 Share Price $14.50 * Est. Cost/Share $26.42 Unrealized @ Report Date -27.1%
— KINNATE BIOPHARMA INC 0.2%
Value $6.084M Shares 264,293 Share Price $23.02 Est. Cost/Share $39.78 Unrealized @ Report Date —
LUNG PULMONX CORP 0.1%
Value $4.914M Shares 136,576 Share Price $35.98 * Est. Cost/Share $48.97 Unrealized @ Report Date -19.7%
— DECIPHERA PHARMACEUTICALS IN 0.1%
Value $4.869M Shares 143,297 Share Price $33.98 Est. Cost/Share $33.98 Unrealized @ Report Date —
BIIB BIOGEN INC 0.1%
Value $4.783M Shares 16,900 Share Price $283.02 * Est. Cost/Share $281.08 Unrealized @ Report Date +16.6%
CERT CERTARA INC 0.1%
Value $4.734M Shares 143,028 Share Price $33.10 * Est. Cost/Share $36.23 Unrealized @ Report Date -16.7%
— BCLS ACQUISITION CORP 0.1%
Value $4.641M Shares 464,103 Share Price $10.00 Est. Cost/Share $11.03 Unrealized @ Report Date —
— JIYA ACQUISITION CORP 0.1%
Value $4.539M Shares 464,103 Share Price $9.78 Est. Cost/Share $10.30 Unrealized @ Report Date —
— VECTIVBIO HLDG AG 0.1%
Value $4.208M Shares 544,706 Share Price $7.73 Est. Cost/Share $11.66 Unrealized @ Report Date —
— MIRATI THERAPEUTICS INC 0.1%
Value $2.654M Shares 15,000 Share Price $176.93 Est. Cost/Share — Unrealized @ Report Date —
BYSI BEYONDSPRING INC 0.1%
Value $2.548M Shares 161,697 Share Price $15.76 * Est. Cost/Share $17.97 Unrealized @ Report Date 0.0%
PRCT PROCEPT BIOROBOTICS CORP 0.1%
Value $2.48M Shares 65,000 Share Price $38.15 Est. Cost/Share $38.38 Unrealized @ Report Date 0.0%
SPRY SILVERBACK THERAPEUTICS INC 0.1%
Value $1.879M Shares 188,243 Share Price $9.98 * Est. Cost/Share $33.40 Unrealized @ Report Date -26.2%
— ADAPTIMMUNE THERAPEUTICS PLC 0.0%
Value $1.509M Shares 291,800 Share Price $5.17 Est. Cost/Share — Unrealized @ Report Date —
— ALLENA PHARMACEUTICALS 0.0%
Value $256K Shares 284,285 Share Price $0.90 Est. Cost/Share $0.96 Unrealized @ Report Date —