Location: San Francisco, CA
CIK: 0001442756 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $2.937B (97.0% shares, 3.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| RCUS | ARCUS BIOSCIENCES INC | 3,431,010 | $139M | 4.7% | $40.47 * | $22.17 | +75.0% | COM | 03969F109 |
| — | OUTSET MED INC | 2,940,255 | $136M | 4.6% | $46.09 | $45.84 | — | COM | 690145107 |
| ABBV | ABBVIE INC | 916,496 | $124M | 4.2% | $135.40 * | $72.26 | +40.7% | COM | 00287Y109 |
| — | HORIZON THERAPEUTICS PUB L | 1,091,840 | $118M | 4.0% | $107.76 | $64.47 | — | SHS | G46188101 |
| CYTK | CYTOKINETICS INC | 2,465,016 | $112M | 3.8% | $45.58 * | $24.28 | +58.9% | COM NEW | 23282W605 |
| CNC | CENTENE CORP DEL | 1,112,480 | $91.67M | 3.1% | $82.40 * | $66.53 | +10.1% | COM | 15135B101 |
| AVTR | AVANTOR INC | 2,079,657 | $87.64M | 3.0% | $42.14 * | $23.15 | +70.2% | COM | 05352A100 |
| LLY | LILLY ELI & CO | 298,643 | $82.49M | 2.8% | $276.22 * | $156.24 | +56.1% | COM | 532457108 |
| PFE | PFIZER INC | 1,343,384 | $79.33M | 2.7% | $59.05 * | $40.23 | 0.0% | COM | 717081103 |
| ERAS | ERASCA INC | 5,191,405 | $76.95M | 2.6% | $14.82 * | $20.63 | -17.0% | COM | 29479A108 |
| IQV | IQVIA HLDGS INC | 238,039 | $67.16M | 2.3% | $282.14 * | $142.23 | +82.5% | COM | 46266C105 |
| HUM | HUMANA INC | 139,420 | $64.67M | 2.2% | $463.86 * | $339.61 | +25.1% | COM | 444859102 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 523,982 | $61.67M | 2.1% | $117.69 * | $91.74 | 0.0% | COM | 450056106 |
| UHS | UNIVERSAL HLTH SVCS INC | 475,340 | $61.63M | 2.1% | $129.66 * | $123.62 | +1.7% | CL B | 913903100 |
| CRBU | CARIBOU BIOSCIENCES INC | 4,092,309 | $59.42M | 2.0% | $14.52 * | $24.45 | -20.4% | COM | 142038108 |
| DHR | DANAHER CORPORATION | 175,690 | $57.8M | 2.0% | $329.01 * | $143.93 | +87.7% | COM | 235851102 |
| UNH | UNITEDHEALTH GROUP INC | 111,554 | $56.02M | 1.9% | $502.14 * | $311.60 | +35.5% | COM | 91324P102 |
| MYGN | MYRIAD GENETICS INC | 2,025,681 | $55.91M | 1.9% | $27.60 * | $28.44 | +1.9% | COM | 62855J104 |
| JNJ | JOHNSON & JOHNSON | 324,972 | $55.59M | 1.9% | $171.07 * | $145.09 | 0.0% | COM | 478160104 |
| — | DYNAVAX TECHNOLOGIES CORP | 3,805,370 | $53.54M | 1.8% | $14.07 | $8.25 | — | COM NEW | 268158201 |
| ICUI | ICU MED INC | 220,587 | $52.35M | 1.8% | $237.34 | $183.12 | +27.6% | COM | 44930G107 |
| PEN | PENUMBRA INC | 177,088 | $50.88M | 1.7% | $287.32 * | $227.41 | +16.3% | COM | 70975L107 |
| HCA | HCA HEALTHCARE INC | 195,621 | $50.26M | 1.7% | $256.92 * | $114.42 | +106.3% | COM | 40412C101 |
| ICLR | ICON PLC | 158,183 | $48.99M | 1.7% | $309.70 * | $192.01 | +45.7% | SHS | G4705A100 |
| EW | EDWARDS LIFESCIENCES CORP | 373,492 | $48.39M | 1.6% | $129.55 * | $66.52 | +75.3% | COM | 28176E108 |
| — | BIOMARIN PHARMACEUTICAL INC | 45,910,000 | $48.12M | 1.6% | $1.05 | $1.04 | — | NOTE 0.599% 8/0 | 09061GAH4 |
| — | MIRATI THERAPEUTICS INC | 315,449 | $46.27M | 1.6% | $146.69 | $167.15 | — | COM | 60468T105 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 2,103,512 | $46.05M | 1.6% | $21.89 * | $20.95 | -11.8% | COM | 87164F105 |
| AZN | ASTRAZENECA PLC | 785,748 | $45.77M | 1.6% | $58.25 | $57.66 | — | SPONSORED ADR | 046353108 |
| MCK | MCKESSON CORP | 177,000 | $44M | 1.5% | $248.57 * | $163.53 | +31.3% | COM | 58155Q103 |
| WAT | WATERS CORP | 117,634 | $43.83M | 1.5% | $372.60 * | $237.41 | +47.3% | COM | 941848103 |
| THC | TENET HEALTHCARE CORP | 525,927 | $42.96M | 1.5% | $81.69 * | $29.15 | +150.7% | COM NEW | 88033G407 |
| — | CATALENT INC | 326,700 | $41.83M | 1.4% | $128.03 | $130.77 | — | COM | 148806102 |
| — | ISHARES TR | 272,800 | $41.63M | 1.4% | $152.62 | — | — | Call | 464287906 |
| — | SEAGEN INC | 268,527 | $41.51M | 1.4% | $154.60 | $157.88 | — | COM | 81181C104 |
| TMO | THERMO FISHER SCIENTIFIC INC | 62,143 | $41.46M | 1.4% | $667.24 * | $505.13 | +22.2% | COM | 883556102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 464,940 | $41.08M | 1.4% | $88.35 * | $82.51 | 0.0% | COM | 09061G101 |
| — | AERIE PHARMACEUTICALS INC | 48,150,000 | $40.25M | 1.4% | $0.84 | $0.81 | — | NOTE 1.500%10/0 | 00771VAB4 |
| — | NEVRO CORP | 485,135 | $39.33M | 1.3% | $81.07 | $124.58 | — | COM | 64157F103 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 394,058 | $33.56M | 1.1% | $85.17 * | $104.37 | -11.9% | COM | 64125C109 |
| — | JOUNCE THERAPEUTICS INC | 3,972,868 | $33.17M | 1.1% | $8.35 | $9.79 | — | COM | 481116101 |
| CAH | CARDINAL HEALTH INC | 639,783 | $32.94M | 1.1% | $51.49 * | $44.62 | 0.0% | COM | 14149Y108 |
| HRTX | HERON THERAPEUTICS INC | 3,512,348 | $32.07M | 1.1% | $9.13 * | $15.87 | -35.7% | COM | 427746102 |
| — | SPDR SER TR | 246,100 | $27.55M | 0.9% | $111.96 | — | — | Call | 78464A900 |
| SOPH | SOPHIA GENETICS SA | 1,952,152 | $27.52M | 0.9% | $14.10 * | $17.59 | -16.2% | ORDINARY SHARES | H82027105 |
| — | KARUNA THERAPEUTICS INC | 177,091 | $23.2M | 0.8% | $131.00 | $119.76 | — | COM | 48576A100 |
| MOH | MOLINA HEALTHCARE INC | 70,088 | $22.29M | 0.8% | $318.09 * | $130.27 | +128.3% | COM | 60855R100 |
| NTLA | INTELLIA THERAPEUTICS INC | 178,222 | $21.07M | 0.7% | $118.24 * | $67.12 | +86.6% | COM | 45826J105 |
| ELV | ANTHEM INC | 42,734 | $19.81M | 0.7% | $463.54 * | $397.15 | 0.0% | COM | 036752103 |
| — | CANO HEALTH INC | 1,914,639 | $17.06M | 0.6% | $8.91 | $12.10 | — | COM CL A | 13781Y103 |
| — | IVERIC BIO INC | 1,005,216 | $16.81M | 0.6% | $16.72 | $16.24 | — | COM | 46583P102 |
| NVAX | NOVAVAX INC | 88,663 | $12.69M | 0.4% | $143.07 * | $134.12 | +28.1% | COM NEW | 670002401 |
| — | PRAXIS PRECISION MEDICINES I | 635,904 | $12.53M | 0.4% | $19.70 | $18.68 | — | COM | 74006W108 |
| BFLY | BUTTERFLY NETWORK INC | 1,828,311 | $12.23M | 0.4% | $6.69 * | $19.79 | -55.6% | COM CL A | 124155102 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 3,201,066 | $12M | 0.4% | $3.75 | $5.53 | — | SPONDS ADR | 00653A107 |
| INCY | INCYTE CORP | 129,428 | $9.5M | 0.3% | $73.40 * | $67.41 | 0.0% | COM | 45337C102 |
| — | OAK STR HEALTH INC | 279,357 | $9.258M | 0.3% | $33.14 | $33.14 | — | COM | 67181A107 |
| IOBT | IO BIOTECH INC | 1,362,144 | $7.744M | 0.3% | $5.69 * | $9.66 | 0.0% | COM | 449778109 |
| — | AERIE PHARMACEUTICALS INC | 1,088,566 | $7.642M | 0.3% | $7.02 | $19.89 | — | COM | 00771V108 |
| LUNG | PULMONX CORP | 209,193 | $6.709M | 0.2% | $32.07 * | $44.65 | -18.2% | COM | 745848101 |
| PMVP | PMV PHARMACEUTICALS INC | 288,334 | $6.661M | 0.2% | $23.10 * | $33.40 | -27.7% | COM | 69353Y103 |
| — | PARDES BIOSCIENCES INC | 361,528 | $5.918M | 0.2% | $16.37 | $16.37 | — | COM | 69945Q105 |
| GILD | GILEAD SCIENCES INC | 76,993 | $5.59M | 0.2% | $72.60 * | $53.94 | +9.0% | COM | 375558103 |
| HOWL | WEREWOLF THERAPEUTICS INC | 400,000 | $4.764M | 0.2% | $11.91 * | $13.70 | +10.2% | COM | 95075A107 |
| — | KINNATE BIOPHARMA INC | 264,293 | $4.683M | 0.2% | $17.72 | $39.78 | — | COM | 49705R105 |
| — | BCLS ACQUISITION CORP | 464,103 | $4.548M | 0.2% | $9.80 | $11.03 | — | COM CL A | G0904B105 |
| — | JIYA ACQUISITION CORP | 464,103 | $4.534M | 0.2% | $9.77 | $10.30 | — | COM CL A | 47760M102 |
| LAB | FLUIDIGM CORP DEL | 980,505 | $3.844M | 0.1% | $3.92 * | $8.84 | -47.0% | COM | 34385P108 |
| DXCM | DEXCOM INC | 4,469 | $2.4M | 0.1% | $537.03 * | $126.11 | +13.9% | COM | 252131107 |
| PRCT | PROCEPT BIOROBOTICS CORP | 65,000 | $1.626M | 0.1% | $25.02 * | $38.38 | -3.6% | COM | 74276L105 |
| — | ALLENA PHARMACEUTICALS | 284,285 | $168K | 0.0% | $0.59 | $0.96 | — | COM | 018119107 |