Location: Larkspur, CA
CIK: 0001425738 · Show all filings
Period: Q3 2022 (← Previous) (Next →)
Filing Date: Nov 14, 2022
Total Value: $2.578B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FATE | FATE THERAPEUTICS INC | 12,957,222 | $290M | 11.3% | $22.41 * | $13.22 | +118.5% | COM | 31189P102 |
| FOLD | AMICUS THERAPEUTICS INC | 21,719,191 | $227M | 8.8% | $10.44 * | $10.66 | +4.5% | COM | 03152W109 |
| KRYS | KRYSTAL BIOTECH INC | 1,899,545 | $132M | 5.1% | $69.70 * | $43.92 | +64.5% | COM | 501147102 |
| ARGX | ARGENX SE | 280,026 | $98.86M | 3.8% | $353.05 | $87.46 | — | SPONSORED ADR | 04016X101 |
| PLRX | PLIANT THERAPEUTICS INC | 4,508,204 | $94.18M | 3.7% | $20.89 * | $24.18 | -20.9% | COM | 729139105 |
| XENE | XENON PHARMACEUTICALS INC | 2,370,614 | $85.58M | 3.3% | $36.10 | $32.01 | +12.3% | COM | 98420N105 |
| BEAM | BEAM THERAPEUTICS INC | 1,772,987 | $84.47M | 3.3% | $47.64 * | $25.01 | +128.1% | COM | 07373V105 |
| LIVN | LIVANOVA PLC | 1,536,362 | $78M | 3.0% | $50.77 * | $76.69 | -22.6% | SHS | G5509L101 |
| — | IGM BIOSCIENCES INC | 3,334,355 | $75.82M | 2.9% | $22.74 | $22.36 | — | COM | 449585108 |
| — | 1LIFE HEALTHCARE INC | 4,087,625 | $70.1M | 2.7% | $17.15 | $10.28 | — | COM | 68269G107 |
| REPL | REPLIMUNE GROUP INC | 3,645,309 | $62.95M | 2.4% | $17.27 * | $21.94 | -13.1% | COM | 76029N106 |
| KYMR | KYMERA THERAPEUTICS INC | 2,876,637 | $62.62M | 2.4% | $21.77 * | $32.56 | -19.0% | COM | 501575104 |
| — | IVERIC BIO INC | 3,399,900 | $60.99M | 2.4% | $17.94 | $17.33 | — | COM | 46583P102 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,985,151 | $55.8M | 2.2% | $28.11 * | $11.60 | +164.4% | COM NEW | 15117B202 |
| — | DECIPHERA PHARMACEUTICALS IN | 2,973,029 | $55M | 2.1% | $18.50 | $19.88 | — | COM | 24344T101 |
| — | AKERO THERAPEUTICS INC | 1,591,085 | $54.18M | 2.1% | $34.05 | $28.43 | — | COM | 00973Y108 |
| — | VERVE THERAPEUTICS INC | 1,505,126 | $51.7M | 2.0% | $34.35 | $57.66 | — | COM | 92539P101 |
| RGNX | REGENXBIO INC | 1,917,212 | $50.67M | 2.0% | $26.43 * | $33.26 | -10.8% | COM | 75901B107 |
| VTYX | VENTYX BIOSCIENCES INC | 1,365,000 | $47.65M | 1.8% | $34.91 * | $22.14 | 0.0% | COM | 92332V107 |
| — | IMMUNOGEN INC | 8,548,145 | $40.86M | 1.6% | $4.78 | $5.30 | — | COM | 45253H101 |
| NRIX | NURIX THERAPEUTICS INC | 3,006,684 | $39.18M | 1.5% | $13.03 * | $27.39 | -42.2% | COM | 67080M103 |
| ADCT | ADC THERAPEUTICS SA | 7,512,029 | $36.21M | 1.4% | $4.82 * | $37.09 | -80.5% | SHS | H0036K147 |
| — | ZYMEWORKS INC | 5,765,818 | $35.46M | 1.4% | $6.15 | $10.92 | — | COM | 98985W102 |
| PEN | PENUMBRA INC | 178,792 | $33.9M | 1.3% | $189.60 * | $160.46 | 0.0% | COM | 70975L107 |
| — | REPARE THERAPEUTICS INC | 2,684,396 | $32.56M | 1.3% | $12.13 | $30.51 | — | COM | 760273102 |
| ELV | ELEVANCE HEALTH INC | 70,487 | $32.02M | 1.2% | $454.24 | $296.65 | +53.5% | COM | 036752103 |
| — | SCIENCE 37 HOLDINGS INC | 19,808,234 | $31.89M | 1.2% | $1.61 | $12.47 | — | COM | 808644108 |
| PRTA | PROTHENA CORP PLC | 525,575 | $31.87M | 1.2% | $60.63 * | $18.81 | +68.0% | SHS | G72800108 |
| SYK | STRYKER CORPORATION | 157,321 | $31.86M | 1.2% | $202.54 | $203.02 | 0.0% | COM | 863667101 |
| TRDA | ENTRADA THERAPEUTICS INC | 1,954,419 | $30.8M | 1.2% | $15.76 | $17.12 | — | COM | 29384C108 |
| — | MEDAVAIL HOLDINGS INC | 34,604,516 | $26.85M | 1.0% | $0.78 | $5.65 | — | COM | 58406B103 |
| — | OAK STR HEALTH INC | 1,061,295 | $26.02M | 1.0% | $24.52 | $49.25 | — | COM | 67181A107 |
| ABSI | ABSCI CORPORATION | 8,031,094 | $25.14M | 1.0% | $3.13 * | $19.41 | -81.1% | COM | 00091E109 |
| SKIN | THE BEAUTY HEALTH COMPANY | 2,109,564 | $24.87M | 1.0% | $11.79 * | $15.00 | -15.7% | COM CL A | 88331L108 |
| — | ATARA BIOTHERAPEUTICS INC | 6,242,756 | $23.6M | 0.9% | $3.78 | $23.37 | — | COM | 046513107 |
| CNC | CENTENE CORP DEL | 282,460 | $21.98M | 0.9% | $77.81 * | $77.15 | +15.8% | COM | 15135B101 |
| SRRK | SCHOLAR ROCK HLDG CORP | 3,140,026 | $21.76M | 0.8% | $6.93 * | $16.67 | -50.0% | COM | 80706P103 |
| ANNX | ANNEXON INC | 3,503,190 | $21.65M | 0.8% | $6.18 * | $21.71 | -75.1% | COM | 03589W102 |
| — | AUGMEDIX INC | 14,380,327 | $20.85M | 0.8% | $1.45 | $3.15 | — | COM | 05105P107 |
| — | RAPT THERAPEUTICS INC | 784,832 | $18.88M | 0.7% | $24.06 | $21.67 | — | COM | 75382E109 |
| IONS | IONIS PHARMACEUTICALS INC | 407,659 | $18.03M | 0.7% | $44.23 * | $42.14 | 0.0% | COM | 462222100 |
| — | GRITSTONE BIO INC | 6,952,760 | $17.87M | 0.7% | $2.57 | $8.41 | — | COM | 39868T105 |
| STVN | STEVANATO GROUP S P A | 946,825 | $16.04M | 0.6% | $16.94 | $23.29 | -28.3% | ORD SHS | T9224W109 |
| — | ALLAKOS INC | 2,545,275 | $15.58M | 0.6% | $6.12 | $50.94 | — | COM | 01671P100 |
| STTK | SHATTUCK LABS INC | 5,619,914 | $15.17M | 0.6% | $2.70 * | $32.14 | -88.3% | COM | 82024L103 |
| — | ALLOVIR INC | 1,907,969 | $15.05M | 0.6% | $7.89 | $16.35 | — | COM | 019818103 |
| — | LAVA THERAPEUTICS NV | 2,816,196 | $12.87M | 0.5% | $4.57 | $15.19 | — | SHS | N51517105 |
| RVMD | REVOLUTION MEDICINES INC | 625,000 | $12.32M | 0.5% | $19.72 * | $21.98 | 0.0% | COM | 76155X100 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 81,464 | $10.86M | 0.4% | $133.29 * | $161.99 | -6.1% | SHS USD | G50871105 |
| STOK | STOKE THERAPEUTICS INC | 835,830 | $10.73M | 0.4% | $12.84 * | $26.54 | -40.0% | COM | 86150R107 |
| BVS | BIOVENTUS INC | 1,299,139 | $9.094M | 0.4% | $7.00 * | $14.24 | -45.0% | COM CL A | 09075A108 |
| — | CUTERA INC | 194,573 | $8.873M | 0.3% | $45.60 | $45.60 | — | COM | 232109108 |
| HUM | HUMANA INC | 16,961 | $8.229M | 0.3% | $485.17 * | $469.33 | 0.0% | COM | 444859102 |
| TOI | THE ONCOLOGY INSTITUTE INC | 1,583,158 | $7.33M | 0.3% | $4.63 * | $8.92 | -34.1% | COM | 68236X100 |
| ALXO | ALX ONCOLOGY HLDGS INC | 752,097 | $7.198M | 0.3% | $9.57 * | $51.82 | -77.5% | COM | 00166B105 |
| NUVB | NUVATION BIO INC | 3,031,009 | $6.789M | 0.3% | $2.24 * | $11.18 | -74.5% | COM CL A | 67080N101 |
| — | HOOKIPA PHARMA INC | 4,562,248 | $6.113M | 0.2% | $1.34 | $4.06 | — | COM | 43906K100 |
| IVVD | INVIVYD INC | 1,920,960 | $6.013M | 0.2% | $3.13 * | $37.11 | -89.2% | COM | 00534A102 |
| — | INVITAE CORP | 2,280,403 | $5.61M | 0.2% | $2.46 | $39.75 | — | COM | 46185L103 |
| — | SOMALOGIC INC | 1,870,839 | $5.425M | 0.2% | $2.90 | $12.36 | — | CLASS A COM | 83444K105 |
| — | ACHILLES THERAPEUTICS PLC | 1,608,089 | $3.634M | 0.1% | $2.26 | $16.55 | — | SPONSORED ADS | 00449L102 |
| STXS | STEREOTAXIS INC | 1,487,495 | $2.677M | 0.1% | $1.80 * | $3.05 | -29.8% | COM NEW | 85916J409 |
| — | NEOLEUKIN THERAPEUTICS INC | 3,436,935 | $2.2M | 0.1% | $0.64 | $11.83 | — | COM | 64049K104 |
| — | TCR2 THERAPEUTICS INC | 1,094,645 | $1.97M | 0.1% | $1.80 | $17.10 | — | COM | 87808K106 |
| TKNO | ALPHA TEKNOVA INC | 558,099 | $1.864M | 0.1% | $3.34 * | $25.30 | -77.9% | COM | 02080L102 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 1,046,587 | $1.633M | 0.1% | $1.56 * | $2.16 | -23.4% | COM | 98422E103 |
| — | ATRECA INC | 800,306 | $1.256M | 0.0% | $1.57 | $15.87 | — | CL A COM | 04965G109 |
| — | SONENDO INC | 498,131 | $533K | 0.0% | $1.07 | $5.76 | — | COM | 835431107 |
| CABA | CABALETTA BIO INC | 696,377 | $453K | 0.0% | $0.65 * | $11.85 | -89.8% | COM | 12674W109 |
| CTSO | CYTOSORBENTS CORP | 266,365 | $362K | 0.0% | $1.36 * | $9.04 | -78.4% | COM NEW | 23283X206 |