Location: Larkspur, CA
CIK: 0001425738 · Show all filings
Period: Q4 2022 (← Previous) (Next →)
Filing Date: Feb 14, 2023
Total Value: $2.445B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 20,249,789 | $247M | 10.1% | $12.21 * | $10.66 | +5.6% | COM | 03152W109 |
| KRYS | KRYSTAL BIOTECH INC | 1,896,645 | $150M | 6.1% | $79.22 * | $43.92 | +69.0% | COM | 501147102 |
| — | AKERO THERAPEUTICS INC | 2,632,912 | $144M | 5.9% | $54.80 | $38.86 | — | COM | 00973Y108 |
| REPL | REPLIMUNE GROUP INC | 4,831,709 | $131M | 5.4% | $27.20 * | $21.66 | -4.1% | COM | 76029N106 |
| FATE | FATE THERAPEUTICS INC | 12,957,222 | $131M | 5.3% | $10.09 * | $13.22 | +42.0% | COM | 31189P102 |
| — | IVERIC BIO INC | 4,502,111 | $96.39M | 3.9% | $21.41 | $18.33 | — | COM | 46583P102 |
| XENE | XENON PHARMACEUTICALS INC | 2,360,414 | $93.07M | 3.8% | $39.43 * | $32.01 | +13.8% | COM | 98420N105 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,977,451 | $88.13M | 3.6% | $44.57 * | $11.60 | +207.9% | COM NEW | 15117B202 |
| PLRX | PLIANT THERAPEUTICS INC | 3,878,599 | $74.97M | 3.1% | $19.33 * | $24.18 | -13.5% | COM | 729139105 |
| BEAM | BEAM THERAPEUTICS INC | 1,770,587 | $69.25M | 2.8% | $39.11 * | $25.01 | +79.1% | COM | 07373V105 |
| KYMR | KYMERA THERAPEUTICS INC | 2,673,837 | $66.74M | 2.7% | $24.96 * | $32.56 | -18.1% | COM | 501575104 |
| LIVN | LIVANOVA PLC | 1,106,409 | $61.45M | 2.5% | $55.54 * | $76.69 | -33.4% | SHS | G5509L101 |
| — | DECIPHERA PHARMACEUTICALS IN | 3,593,317 | $58.89M | 2.4% | $16.39 | $19.28 | — | COM | 24344T101 |
| — | IGM BIOSCIENCES INC | 3,334,355 | $56.72M | 2.3% | $17.01 | $22.36 | — | COM | 449585108 |
| ARGX | ARGENX SE | 148,517 | $56.26M | 2.3% | $378.83 | $87.46 | — | SPONSORED ADR | 04016X101 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 318,945 | $50.81M | 2.1% | $159.31 * | $150.50 | -2.6% | SHS USD | G50871105 |
| PEN | PENUMBRA INC | 221,809 | $49.34M | 2.0% | $222.46 * | $167.26 | +16.9% | COM | 70975L107 |
| ZYME | ZYMEWORKS DEL INC | 6,175,918 | $48.54M | 2.0% | $7.86 * | $7.03 | 0.0% | COM | 98985Y108 |
| RGNX | REGENXBIO INC | 1,913,512 | $43.4M | 1.8% | $22.68 | $33.26 | -32.0% | COM | 75901B107 |
| — | IMMUNOGEN INC | 8,532,817 | $42.32M | 1.7% | $4.96 | $5.30 | — | COM | 45253H101 |
| PRME | PRIME MEDICINE INC | 2,209,350 | $41.05M | 1.7% | $18.58 * | $18.06 | 0.0% | COM | 74168J101 |
| — | REPARE THERAPEUTICS INC | 2,684,396 | $39.49M | 1.6% | $14.71 | $30.51 | — | COM | 760273102 |
| — | 1LIFE HEALTHCARE INC | 2,326,625 | $38.88M | 1.6% | $16.71 | $10.28 | — | COM | 68269G107 |
| NRIX | NURIX THERAPEUTICS INC | 3,000,784 | $32.95M | 1.3% | $10.98 * | $27.39 | -56.0% | COM | 67080M103 |
| — | OAK STR HEALTH INC | 1,420,617 | $30.56M | 1.2% | $21.51 | $42.24 | — | COM | 67181A107 |
| VTYX | VENTYX BIOSCIENCES INC | 894,974 | $29.35M | 1.2% | $32.79 * | $22.14 | +33.8% | COM | 92332V107 |
| ADCT | ADC THERAPEUTICS SA | 7,590,849 | $29.15M | 1.2% | $3.84 * | $36.74 | -89.1% | SHS | H0036K147 |
| SYK | STRYKER CORPORATION | 105,880 | $25.89M | 1.1% | $244.49 * | $203.02 | +8.2% | COM | 863667101 |
| TRDA | ENTRADA THERAPEUTICS INC | 1,854,108 | $25.07M | 1.0% | $13.52 | $17.12 | — | COM | 29384C108 |
| — | GRITSTONE BIO INC | 6,931,460 | $23.91M | 1.0% | $3.45 | $8.41 | — | COM | 39868T105 |
| — | VERVE THERAPEUTICS INC | 1,221,903 | $23.64M | 1.0% | $19.35 | $57.66 | — | COM | 92539P101 |
| CNC | CENTENE CORP DEL | 281,260 | $23.07M | 0.9% | $82.01 | $77.15 | +5.9% | COM | 15135B101 |
| — | AUGMEDIX INC | 14,380,327 | $22.43M | 0.9% | $1.56 | $3.15 | — | COM | 05105P107 |
| — | ALLAKOS INC | 2,545,275 | $21.43M | 0.9% | $8.42 | $50.94 | — | COM | 01671P100 |
| — | ATARA BIOTHERAPEUTICS INC | 6,242,756 | $20.48M | 0.8% | $3.28 | $23.37 | — | COM | 046513107 |
| ELV | ELEVANCE HEALTH INC | 38,970 | $19.99M | 0.8% | $512.97 * | $296.65 | +63.3% | COM | 036752103 |
| IMVT | IMMUNOVANT INC | 1,088,131 | $19.31M | 0.8% | $17.75 * | $12.59 | 0.0% | COM | 45258J102 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,095,820 | $18.97M | 0.8% | $9.05 * | $16.67 | -51.9% | COM | 80706P103 |
| ANNX | ANNEXON INC | 3,503,190 | $18.11M | 0.7% | $5.17 * | $21.71 | -74.7% | COM | 03589W102 |
| STVN | STEVANATO GROUP S P A | 942,525 | $16.94M | 0.7% | $17.97 * | $23.29 | -29.3% | ORD SHS | T9224W109 |
| ABSI | ABSCI CORPORATION | 8,031,094 | $16.87M | 0.7% | $2.10 * | $19.41 | -85.9% | COM | 00091E109 |
| — | RAPT THERAPEUTICS INC | 784,832 | $15.54M | 0.6% | $19.80 | $21.67 | — | COM | 75382E109 |
| RVMD | REVOLUTION MEDICINES INC | 625,000 | $14.89M | 0.6% | $23.82 * | $21.98 | -3.3% | COM | 76155X100 |
| STTK | SHATTUCK LABS INC | 5,619,914 | $12.93M | 0.5% | $2.30 * | $32.14 | -92.2% | COM | 82024L103 |
| — | MEDAVAIL HOLDINGS INC | 34,604,516 | $10.37M | 0.4% | $0.30 | $5.65 | — | COM | 58406B103 |
| IONS | IONIS PHARMACEUTICALS INC | 266,187 | $10.05M | 0.4% | $37.77 * | $42.14 | -0.2% | COM | 462222100 |
| — | LAVA THERAPEUTICS NV | 2,816,196 | $9.857M | 0.4% | $3.50 | $15.19 | — | SHS | N51517105 |
| — | ALLOVIR INC | 1,907,969 | $9.788M | 0.4% | $5.13 | $16.35 | — | COM | 019818103 |
| — | SCIENCE 37 HOLDINGS INC | 19,808,234 | $8.224M | 0.3% | $0.42 | $12.47 | — | COM | 808644108 |
| ALXO | ALX ONCOLOGY HLDGS INC | 607,470 | $6.846M | 0.3% | $11.27 | $51.82 | -78.3% | COM | 00166B105 |
| STOK | STOKE THERAPEUTICS INC | 642,430 | $5.93M | 0.2% | $9.23 * | $26.54 | -60.8% | COM | 86150R107 |
| NUVB | NUVATION BIO INC | 3,031,009 | $5.82M | 0.2% | $1.92 * | $11.18 | -81.9% | COM CL A | 67080N101 |
| CABA | CABALETTA BIO INC | 464,252 | $4.294M | 0.2% | $9.25 * | $11.85 | -69.3% | COM | 12674W109 |
| — | INVITAE CORP | 2,280,403 | $4.242M | 0.2% | $1.86 | $39.75 | — | COM | 46185L103 |
| — | SOMALOGIC INC | 1,500,000 | $3.765M | 0.2% | $2.51 | $12.36 | — | CLASS A COM | 83444K105 |
| TKNO | ALPHA TEKNOVA INC | 558,099 | $3.148M | 0.1% | $5.64 * | $25.30 | -82.5% | COM | 02080L102 |
| STXS | STEREOTAXIS INC | 1,487,495 | $3.079M | 0.1% | $2.07 * | $3.05 | -36.0% | COM NEW | 85916J409 |
| GRFS | GRIFOLS S A | 325,600 | $2.768M | 0.1% | $8.50 | $8.50 | — | SP ADR REP B NVT | 398438408 |
| TOI | THE ONCOLOGY INSTITUTE INC | 1,583,158 | $2.612M | 0.1% | $1.65 * | $8.92 | -68.5% | COM | 68236X100 |
| — | HOOKIPA PHARMA INC | 3,114,768 | $2.523M | 0.1% | $0.81 | $4.06 | — | COM | 43906K100 |
| IVVD | INVIVYD INC | 1,440,725 | $2.161M | 0.1% | $1.50 * | $37.11 | -92.5% | COM | 00534A102 |
| — | ACHILLES THERAPEUTICS PLC | 1,608,089 | $1.447M | 0.1% | $0.90 | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | SONENDO INC | 498,131 | $1.41M | 0.1% | $2.83 | $5.76 | — | COM | 835431107 |
| BVS | BIOVENTUS INC | 535,950 | $1.399M | 0.1% | $2.61 * | $14.24 | -69.3% | COM CL A | 09075A108 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 1,046,587 | $1.392M | 0.1% | $1.33 * | $2.16 | -34.6% | COM | 98422E103 |
| — | NEOLEUKIN THERAPEUTICS INC | 1,850,566 | $942K | 0.0% | $0.51 | $11.83 | — | COM | 64049K104 |
| — | TCR2 THERAPEUTICS INC | 731,379 | $731K | 0.0% | $1.00 | $17.10 | — | COM | 87808K106 |
| CTSO | CYTOSORBENTS CORP | 266,365 | $413K | 0.0% | $1.55 * | $9.04 | -83.6% | COM NEW | 23283X206 |
| — | ATRECA INC | 442,653 | $354K | 0.0% | $0.80 | $15.87 | — | CL A COM | 04965G109 |