BAKER BROS. ADVISORS LP Diversified Active

Location: New York, NY

CIK: 0001263508 · Show all filings

Period: Q2 2013 (Next →)

Filing Date: Aug 14, 2013

Total Value: $5.056B (79.3% shares, 20.7% debt)

Holdings (75)

Pharmacyclics Inc. 16.9%
Value $856M Shares 10,771,138 Est. Cost $79.47 Unrealized
Seattle Genetics Inc. 12.0%
Value $608M Shares 19,322,947 Est. Cost $31.46 Unrealized
Genomic Health Inc. 8.6%
Value $433M Shares 13,650,835 Est. Cost $31.71 Unrealized
Incyte Genomics Notes 4.75% 10/1/2015 7.9%
Value $402M Shares 157,758,000 Est. Cost $2.55 Unrealized
Synageva Biopharma Corp. 7.7%
Value $387M Shares 9,223,182 Est. Cost $41.98 Unrealized
ACAD Acadia Pharmaceuticals Inc. 7.2%
Value $362M Shares 19,955,126 Est. Cost $13.77 Unrealized 0.0%
Salix 2.75% 5/15/15 6.6%
Value $334M Shares 219,440,000 Est. Cost $1.52 Unrealized
INCY Incyte Corp. 6.4%
Value $326M Shares 14,810,559 Est. Cost $21.85 Unrealized 0.0%
Viropharma Inc. 4.8%
Value $244M Shares 8,528,603 Est. Cost $28.65 Unrealized
Auxilium 1.5% 7/15/2018 1.7%
Value $88.1M Shares 91,590,000 Est. Cost $0.96 Unrealized
Xoma Corp. 1.5%
Value $73.6M Shares 20,274,581 Est. Cost $3.63 Unrealized
GILD Gilead Sciences Inc. 1.3%
Value $63.87M Shares 1,245,800 Est. Cost $36.21 Unrealized 0.0%
Biomarin Pharmaceuticals Notes 1.875% 4/23/2017 1.3%
Value $63.22M Shares 22,898,000 Est. Cost $2.76 Unrealized
Aegerion Pharmaceuticals 1.2%
Value $58.55M Shares 924,343 Est. Cost $63.34 Unrealized
HALO Halozyme Therapeutics Inc. 1.0%
Value $52.1M Shares 6,553,150 Est. Cost $6.37 Unrealized 0.0%
Repros Therapeutics 1.0%
Value $51.27M Shares 2,778,654 Est. Cost $18.45 Unrealized
Medivation 2.625% 4/1/17 1.0%
Value $50.05M Shares 39,500,000 Est. Cost $1.27 Unrealized
Gilead 1.625% 5/1/16 1.0%
Value $48.66M Shares 21,500,000 Est. Cost $2.26 Unrealized
Intermune Inc Notes 2.5% 12/15/17 0.9%
Value $43.9M Shares 41,000,000 Est. Cost $1.07 Unrealized
BMRN Biomarin Pharmaceuticals 0.9%
Value $43.66M Shares 783,311 Est. Cost $62.32 Unrealized 0.0%
CERS Cerus 0.7%
Value $37.37M Shares 8,455,306 Est. Cost $4.84 Unrealized 0.0%
Clovis Oncology 0.7%
Value $35.17M Shares 525,113 Est. Cost $66.98 Unrealized
VNDA Vanda Pharmaceuticals, Inc. 0.6%
Value $32.05M Shares 3,966,179 Est. Cost $6.73 Unrealized 0.0%
Ariad Pharmaceuticals Inc. 0.5%
Value $25.36M Shares 1,450,000 Est. Cost $17.49 Unrealized
Stemline Therapeutics Inc. 0.4%
Value $21.46M Shares 900,000 Est. Cost $23.84 Unrealized
Intercept Pharmaceuticals, Inc. 0.4%
Value $20.75M Shares 462,847 Est. Cost $44.84 Unrealized
Medivation Inc. 0.4%
Value $19.6M Shares 398,331 Est. Cost $49.20 Unrealized
Progenics Pharmaceuticals, Inc. 0.4%
Value $18.73M Shares 4,200,000 Est. Cost $4.46 Unrealized
Derma Sciences 0.4%
Value $18.14M Shares 1,358,857 Est. Cost $13.35 Unrealized
Intermune Inc Notes 5% 3/1/15 0.4%
Value $17.76M Shares 16,860,000 Est. Cost $1.05 Unrealized
Avanir Pharmaceuticals 0.3%
Value $16.46M Shares 3,578,591 Est. Cost $4.60 Unrealized
INFIQ Infinity Pharmaceuticals Inc. 0.3%
Value $16.46M Shares 1,016,433 Est. Cost $30.95 Unrealized 0.0%
Questcor Pharmaceuticals, Inc. 0.3%
Value $14.35M Shares 315,846 Est. Cost $45.44 Unrealized
Synergy Pharmaceuticals 0.2%
Value $11.27M Shares 2,608,271 Est. Cost $4.32 Unrealized
Chelsea Therapeutics 0.2%
Value $10.98M Shares 4,775,787 Est. Cost $2.30 Unrealized
Portola Pharmaceuticals, Inc. 0.2%
Value $9.826M Shares 399,914 Est. Cost $24.57 Unrealized
INSM Insmed Inc. 0.2%
Value $9.518M Shares 795,803 Est. Cost $10.22 Unrealized 0.0%
IRWD Ironwood Pharmaceuticals 0.2%
Value $9.157M Shares 922,160 Est. Cost $12.12 Unrealized 0.0%
BCRX Biocryst Pharmaceuticals Inc. 0.2%
Value $8.623M Shares 5,563,615 Est. Cost $1.73 Unrealized 0.0%
Threshold Pharma 0.2%
Value $8.39M Shares 1,595,048 Est. Cost $5.26 Unrealized
Synta Pharmaceuticals 0.1%
Value $6.981M Shares 1,399,040 Est. Cost $4.99 Unrealized
Array Biopharma Inc. 0.1%
Value $6.81M Shares 1,500,000 Est. Cost $4.54 Unrealized
QLT, Inc. 0.1%
Value $6.742M Shares 1,535,863 Est. Cost $4.39 Unrealized
Isis Pharmaceuticals 0.1%
Value $6.638M Shares 247,036 Est. Cost $26.87 Unrealized
Chemocentryx Inc. 0.1%
Value $5.303M Shares 375,000 Est. Cost $14.14 Unrealized
Ambit Biosciences Corp. 0.1%
Value $5.236M Shares 747,962 Est. Cost $7.00 Unrealized
Xenoport 0.1%
Value $5.119M Shares 1,034,112 Est. Cost $4.95 Unrealized
Anacor Pharmaceuticals 0.1%
Value $4.899M Shares 876,463 Est. Cost $5.59 Unrealized
PRTA Prothena Corp. PLC 0.1%
Value $4.772M Shares 369,650 Est. Cost $9.30 Unrealized 0.0%
Kythera Biopharmaceuticals 0.1%
Value $4.463M Shares 165,000 Est. Cost $27.05 Unrealized
Achillion 0.1%
Value $3.722M Shares 455,000 Est. Cost $8.18 Unrealized
PBYI Puma Biotechnology 0.1%
Value $3.697M Shares 83,333 Est. Cost $35.25 Unrealized 0.0%
MEI Pharma, Inc. 0.1%
Value $3.677M Shares 515,612 Est. Cost $7.13 Unrealized
BioDelivery Sciences Intl. Inc. 0.1%
Value $3.656M Shares 900,505 Est. Cost $4.06 Unrealized
Zogenix, Inc. 0.1%
Value $3.422M Shares 2,001,000 Est. Cost $1.71 Unrealized
Salix Pharmaceuticals, Inc. 0.1%
Value $3.015M Shares 45,571 Est. Cost $66.16 Unrealized
Idera Pharmaceuticals Inc. 0.1%
Value $2.948M Shares 4,500,000 Est. Cost $0.66 Unrealized
Ventrus Biosciences, Inc. 0.1%
Value $2.918M Shares 1,215,840 Est. Cost $2.40 Unrealized
Ligand Pharmaceuticals Inc. 0.1%
Value $2.745M Shares 73,400 Est. Cost $37.40 Unrealized
Discovery Laboratories Inc. 0.0%
Value $2.308M Shares 1,518,617 Est. Cost $1.52 Unrealized
ENTA Enanta Pharmaceuticals 0.0%
Value $2.214M Shares 125,000 Est. Cost $19.50 Unrealized 0.0%
Arqule Inc. 0.0%
Value $2.041M Shares 879,805 Est. Cost $2.32 Unrealized
Cytrx Corp. 0.0%
Value $2M Shares 1,000,000 Est. Cost $2.00 Unrealized
Receptos Inc. 0.0%
Value $1.989M Shares 100,000 Est. Cost $19.89 Unrealized
GERN Geron Corp. 0.0%
Value $1.5M Shares 1,000,000 Est. Cost $1.08 Unrealized 0.0%
FOLD Amicus Therapeutics 0.0%
Value $1.2M Shares 515,072 Est. Cost $3.07 Unrealized 0.0%
Tesaro Inc. 0.0%
Value $1.022M Shares 31,218 Est. Cost $32.74 Unrealized
Biodel Inc. 0.0%
Value $961K Shares 229,885 Est. Cost $4.18 Unrealized
OSUR Orasure Technologies Inc. 0.0%
Value $945K Shares 243,467 Est. Cost $4.46 Unrealized 0.0%
Lpath Inc. 0.0%
Value $880K Shares 200,000 Est. Cost $4.40 Unrealized
Epizyme Inc. 0.0%
Value $563K Shares 20,000 Est. Cost $28.15 Unrealized
Ziopharm Oncology Inc. 0.0%
Value $536K Shares 254,199 Est. Cost $2.11 Unrealized
Cubist Pharmaceuticals Inc. 0.0%
Value $241K Shares 5,000 Est. Cost $48.20 Unrealized
Cyclacel Pharmaceuticals Pfd. Conv. Ex 6% 0.0%
Value $151K Shares 20,979 Est. Cost $7.20 Unrealized
Aradigm Corp. 0.0%
Value $16,000 Shares 100,000 Est. Cost $0.16 Unrealized