Location: Palo Alto, CA
CIK: 0001306923 · Show all filings
Period: Q1 2026 (← Previous) (Next →)
Filing Date: May 15, 2026
Total Value: $654M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| INSM | INSMED INC | 415,269 | $67.9M | 10.4% | $163.52 * | $17.79 | +793.9% | COM PAR $.01 | 457669307 |
| ACAD | ACADIA PHARMACEUTICALS INC | 2,872,695 | $63.95M | 9.8% | $22.26 * | $26.72 | -5.7% | COM | 004225108 |
| PTCT | PTC THERAPEUTICS INC | 921,607 | $62.79M | 9.6% | $68.13 * | $46.78 | +57.6% | COM | 69366J200 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 685,182 | $38.71M | 5.9% | $56.49 * | $83.16 | -29.4% | COM | 09061G101 |
| UTHR | UNITED THERAPEUTICS CORP | 62,809 | $37.24M | 5.7% | $592.98 * | $118.03 | +307.1% | COM | 91307C102 |
| ANAB | ANAPTYSBIO INC | 638,161 | $35.39M | 5.4% | $55.46 * | $19.77 | +149.7% | COM | 032724106 |
| MIRM | MIRUM PHARMACEUTICALS INC | 325,175 | $30.04M | 4.6% | $92.38 * | $73.46 | +31.5% | COM | 604749101 |
| DYN | DYNE THERAPEUTICS INC | 1,652,972 | $29.97M | 4.6% | $18.13 * | $13.45 | +27.3% | COM | 26818M108 |
| BIIB | BIOGEN INC | 140,719 | $25.8M | 3.9% | $183.33 | $256.18 | -28.5% | COM | 09062X103 |
| IRON | DISC MEDICINE INC | 401,719 | $25.69M | 3.9% | $63.94 * | $63.80 | +16.1% | COM | 254604101 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 6,349,563 | $22.29M | 3.4% | $3.51 * | $4.09 | -34.4% | COM | 462260100 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 864,986 | $20.21M | 3.1% | $23.36 * | $16.22 | +28.0% | COM | 87164F105 |
| ANNX | ANNEXON INC | 2,948,090 | $16.33M | 2.5% | $5.54 * | $4.19 | +37.1% | COM | 03589W102 |
| FOLD | AMICUS THERAPEUTICS INC | 1,113,045 | $16.09M | 2.5% | $14.46 | $9.63 | +48.6% | COM | 03152W109 |
| NVCR | NOVOCURE LTD | 1,280,439 | $13.96M | 2.1% | $10.90 * | $34.92 | -64.0% | ORD SHS | G6674U108 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 596,495 | $12.5M | 1.9% | $20.95 * | $29.43 | -20.6% | COM | 90400D108 |
| PRTA | PROTHENA CORP PLC | 1,208,568 | $11.75M | 1.8% | $9.72 * | $20.95 | -56.5% | SHS | G72800108 |
| BCAX | BICARA THERAPEUTICS INC | 550,408 | $10.95M | 1.7% | $19.89 * | $16.72 | -2.6% | COM | 055477103 |
| CLDX | CELLDEX THERAPEUTICS INC | 296,408 | $9.402M | 1.4% | $31.72 * | $25.41 | 0.0% | COM NEW | 15117B202 |
| CDNA | CAREDX INC | 531,870 | $9.233M | 1.4% | $17.36 * | $15.56 | +26.5% | COM | 14167L103 |
| ALKS | ALKERMES PLC | 242,560 | $8.577M | 1.3% | $35.36 * | $24.20 | +33.7% | SHS | G01767105 |
| CMPX | COMPASS THERAPEUTICS INC | 1,514,504 | $8.012M | 1.2% | $5.29 * | $4.62 | +29.9% | COM | 20454B104 |
| AGIO | AGIOS PHARMACEUTICALS INC | 213,601 | $7.226M | 1.1% | $33.83 * | $33.17 | -15.5% | COM | 00847X104 |
| ALGN | ALIGN TECHNOLOGY INC | 41,520 | $7.118M | 1.1% | $171.43 | $150.48 | +16.1% | COM | 016255101 |
| CAPR | CAPRICOR THERAPEUTICS INC | 229,763 | $6.985M | 1.1% | $30.40 * | $13.24 | +88.0% | COM NEW | 14070B309 |
| TVTX | TRAVERE THERAPEUTICS INC | 230,453 | $6.847M | 1.0% | $29.71 * | $27.44 | +13.1% | COM | 89422G107 |
| TSHA | TAYSHA GENE THERAPIES INC | 1,391,382 | $6.219M | 1.0% | $4.47 * | $2.31 | +106.4% | COM SHS | 877619106 |
| ACRS | ACLARIS THERAPEUTICS INC | 1,613,430 | $6.05M | 0.9% | $3.75 * | $1.50 | +122.7% | COM | 00461U105 |
| DNLI | DENALI THERAPEUTICS INC | 234,582 | $4.504M | 0.7% | $19.20 * | $15.17 | +29.4% | COM | 24823R105 |
| XENE | XENON PHARMACEUTICALS INC | 51,345 | $2.986M | 0.5% | $58.15 * | $42.00 | -0.0% | COM | 98420N105 |
| ORKA | ORUKA THERAPEUTICS INC | 59,985 | $2.942M | 0.4% | $49.05 * | $14.82 | +118.9% | COM | 687604108 |
| STOK | STOKE THERAPEUTICS INC | 84,631 | $2.756M | 0.4% | $32.56 * | $9.90 | +221.6% | COM | 86150R107 |
| EW | EDWARDS LIFESCIENCES CORP | 33,640 | $2.694M | 0.4% | $80.08 * | $72.66 | +12.8% | COM | 28176E108 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 18,117 | $2.387M | 0.4% | $131.74 | $129.01 | +4.1% | COM | 64125C109 |
| NUVB | NUVATION BIO INC | 508,846 | $2.183M | 0.3% | $4.29 * | $2.12 | +192.4% | COM CL A | 67080N101 |
| CYTK | CYTOKINETICS INC | 32,195 | $2.122M | 0.3% | $65.91 * | $64.44 | 0.0% | COM NEW | 23282W605 |
| EHTH | EHEALTH INC | 1,482,797 | $1.913M | 0.3% | $1.29 * | $38.13 | -92.6% | COM | 28238P109 |
| CRSP | CRISPR THERAPEUTICS AG | 39,605 | $1.884M | 0.3% | $47.57 * | $38.70 | +38.2% | NAMEN AKT | H17182108 |
| BNTX | BIONTECH SE-ADR | 19,614 | $1.743M | 0.3% | $88.88 | $118.77 | — | SPONSORED ADS | 09075V102 |
| PYXS | PYXIS ONCOLOGY INC | 1,010,510 | $1.475M | 0.2% | $1.46 * | $2.98 | -48.7% | COMMON STOCK | 747324101 |
| VSTM | VERASTEM INC | 246,093 | $1.304M | 0.2% | $5.30 * | $6.48 | 0.0% | COM NEW | 92337C203 |
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | 201,890 | $937K | 0.1% | $4.64 | $16.07 | — | SPONSORED ADS | 088786108 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,787 | $935K | 0.1% | $523.47 * | $492.48 | 0.0% | COM | 558868105 |
| HUM | HUMANA INC | 3,985 | $691K | 0.1% | $173.39 * | $369.63 | -39.5% | COM | 444859102 |
| CMPS | COMPASS PATHWAYS PLC ADR | 115,616 | $639K | 0.1% | $5.53 | $6.90 | — | SPONSORED ADS | 20451W101 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 104,410 | $606K | 0.1% | $5.80 * | $7.21 | 0.0% | COM | 98422E103 |
| ABEO | ABEONA THERAPEUTICS INC | 108,865 | $488K | 0.1% | $4.48 * | $6.04 | -14.5% | COM NEW | 00289Y206 |
| INSP | INSPIRE MEDICAL SYSTEMS INC | 8,772 | $452K | 0.1% | $51.58 * | $95.68 | -19.1% | COM | 457730109 |
| URGN | UROGEN PHARMA LTD | 24,500 | $441K | 0.1% | $17.98 * | $27.01 | -22.9% | COM | M96088105 |
| PRQR | PROQR THERAPEUTICS NV | 188,807 | $306K | 0.0% | $1.62 | $2.18 | -25.2% | SHS EURO | N71542109 |
| ALDX | ALDEYRA THERAPEUTICS INC | 155,709 | $263K | 0.0% | $1.69 * | $5.95 | -16.6% | COM | 01438T106 |