TALPHERA INC

Ticker: TLPH CUSIP: 00444T209 Class: COM NEW

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (10)

Empery Asset Management, LP
Value ($000) $1,520 Shares 1,333,497
DIADEMA PARTNERS LP
Value ($000) $156 Shares 136,923
Persistent Asset Partners Ltd
Value ($000) $42 Shares 36,630
CANTOR FITZGERALD, L. P.
Value ($000) $658 Shares 577,490
JANE STREET GROUP, LLC
Value ($000) $97 Shares 84,938
CITADEL ADVISORS LLC
Value ($000) $87 Shares 76,445
SUSQUEHANNA INTERNATIONAL GROUP, LLP
Value ($000) $64 Shares 56,432
TWO SIGMA INVESTMENTS, LP
Value ($000) $28 Shares 24,588
GSA CAPITAL PARTNERS LLP
Value ($000) $0 Shares 20,973
SRS Capital Advisors, Inc.
Value ($000) $0 Shares 81

Increased Positions (11)

Dauntless Investment Group, LLC
Value ($000) $660 (+639.4%) Shares 579,320 (+479.3%)
AIGH Capital Management LLC
Value ($000) $5,314 (+33.6%) Shares 4,661,502 (+4.6%)
VANGUARD GROUP INC
Value ($000) $757 (+194.7%) Shares 663,677 (+131.9%)
RENAISSANCE TECHNOLOGIES LLC
Value ($000) $293 (+554.2%) Shares 257,380 (+412.6%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $391 (+163.0%) Shares 342,987 (+107.0%)
SIMPLEX TRADING, LLC
Value ($000) $98 (+9780900.0%) Shares 85,799 (+6892.6%)
NORTHERN TRUST CORP
Value ($000) $60 (+516.2%) Shares 52,580 (+382.8%)
Mariner, LLC
Value ($000) $66 (+196.1%) Shares 58,000 (+132.0%)
GROUP ONE TRADING, L.P.
Value ($000) $65 (+138.9%) Shares 57,173 (+88.0%)
WELLS FARGO & COMPANY/MN
Value ($000) $1 (+160.1%) Shares 983 (+103.5%)
BANK OF AMERICA CORP /DE/
Value ($000) $0 (+143.3%) Shares 335 (+90.3%)

Decreased Positions (6)

Rosalind Advisors, Inc.
Value ($000) $4,080 (+4.2%) Shares 3,579,273 (-18.4%)
Values First Advisors, Inc.
Value ($000) $93 (+5.9%) Shares 81,208 (-17.0%)
UBS Group AG
Value ($000) $8 (-68.5%) Shares 6,818 (-75.3%)
Tower Research Capital LLC (TRC)
Value ($000) $3 (-42.0%) Shares 2,801 (-54.5%)
SBI Securities Co., Ltd.
Value ($000) $0 (-60.6%) Shares 78 (-69.2%)
Global Retirement Partners, LLC
Value ($000) $0 (-60.0%) Shares 23 (-68.5%)

Exited Positions (7)

PFG Investments, LLC
Value ($000) $9 Shares 10,000
Sterling Capital Management LLC
Value ($000) $2 Shares 2,000
NewEdge Advisors, LLC
Value ($000) $0 Shares 500
Virtu Financial LLC
Value ($000) $0 Shares 32,811
OSAIC HOLDINGS, INC.
Value ($000) $0 Shares 26
BARCLAYS PLC
Value ($000) $0 Shares 11
CITIGROUP INC
Value ($000) $0 Shares 1