NAUTILUS BIOTECHNOLOGY INC

Ticker: NAUT CUSIP: 63909J108 Class: Common Stock

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (11)

SENTINEL TRUST CO LBA
Value ($000) $1 Shares 750,000
OMERS ADMINISTRATION Corp
Value ($000) $204 Shares 104,785
TWO SIGMA SECURITIES, LLC
Value ($000) $32 Shares 16,239
Lighthouse Investment Partners, LLC
Value ($000) $78 Shares 40,200
MARSHALL WACE, LLP
Value ($000) $228 Shares 117,059
Garde Capital, Inc.
Value ($000) $35 Shares 18,000
Point72 Asset Management, L.P.
Value ($000) $119 Shares 60,833
SUSQUEHANNA INTERNATIONAL GROUP, LLP
Value ($000) $84 Shares 42,916
CAPTRUST FINANCIAL ADVISORS
Value ($000) $66 Shares 34,011
Hudson Bay Capital Management LP
Value ($000) $37 Shares 19,062
GROUP ONE TRADING, L.P.
Value ($000) $8 Shares 3,880

Increased Positions (18)

GOLDMAN SACHS GROUP INC
Value ($000) $580 (+483.2%) Shares 297,437 (+152.7%)
VANGUARD GROUP INC
Value ($000) $5,067 (+146.6%) Shares 2,598,223 (+6.8%)
Qube Research & Technologies Ltd
Value ($000) $240 (+450.0%) Shares 123,121 (+138.3%)
CITIGROUP INC
Value ($000) $120 (+16009.5%) Shares 61,712 (+6881.0%)
JANE STREET GROUP, LLC
Value ($000) $403 (+222.1%) Shares 206,837 (+39.6%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $1,989 (+143.3%) Shares 1,019,996 (+5.4%)
Caprock Group, LLC
Value ($000) $86 (+639.8%) Shares 44,090 (+158.0%)
BNP PARIBAS ARBITRAGE, SA
Value ($000) $54 (+4264.8%) Shares 27,711 (+1791.5%)
STATE STREET CORP
Value ($000) $392 (+159.8%) Shares 201,255 (+12.6%)
BANK OF AMERICA CORP /DE/
Value ($000) $39 (+5632.7%) Shares 20,167 (+2380.6%)
Callan Family Office, LLC
Value ($000) $51 (+304.2%) Shares 25,970 (+75.1%)
MORGAN STANLEY
Value ($000) $75 (+246.1%) Shares 38,584 (+50.0%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $1,094 (+133.8%) Shares 560,909 (+1.3%)
BRIDGEWAY CAPITAL MANAGEMENT, LLC
Value ($000) $254 (+140.0%) Shares 130,000 (+4.0%)
UBS Group AG
Value ($000) $10 (+2436.0%) Shares 5,163 (+998.5%)
ROYAL BANK OF CANADA
Value ($000) $6 (+500.0%) Shares 3,274 (+79.7%)
ACADIAN ASSET MANAGEMENT LLC
Value ($000) $1 (+484.7%) Shares 611,984 (+151.6%)
Virtu Financial LLC
Value ($000) $0 (+170.6%) Shares 23,532 (+19.6%)

Decreased Positions (15)

RENAISSANCE TECHNOLOGIES LLC
Value ($000) $507 (-40.5%) Shares 259,900 (-74.2%)
Corient Private Wealth LLC
Value ($000) $224 (-17.0%) Shares 114,788 (-64.0%)
GSA CAPITAL PARTNERS LLP
Value ($000) $0 (+10.5%) Shares 124,051 (-52.1%)
Squarepoint Ops LLC
Value ($000) $22 (-80.2%) Shares 11,316 (-91.4%)
BARCLAYS PLC
Value ($000) $94 (-68.9%) Shares 48,254 (-54.6%)
DIMENSIONAL FUND ADVISORS LP
Value ($000) $556 (+80.7%) Shares 285,439 (-21.7%)
XTX Topco Ltd
Value ($000) $66 (+69.6%) Shares 33,608 (-26.5%)
BlackRock, Inc.
Value ($000) $369 (+117.0%) Shares 189,431 (-6.0%)
NORTHERN TRUST CORP
Value ($000) $209 (+109.6%) Shares 107,011 (-9.2%)
Tower Research Capital LLC (TRC)
Value ($000) $0 (-99.8%) Shares 5 (-99.9%)
FMR LLC
Value ($000) $7 (-7.1%) Shares 3,486 (-59.7%)
Palumbo Wealth Management LLC
Value ($000) $80 (+125.4%) Shares 41,133 (-2.3%)
Vanguard Capital Wealth Advisors
Value ($000) $25 (+122.3%) Shares 13,000 (-3.7%)
EverSource Wealth Advisors, LLC
Value ($000) $0 (-50.3%) Shares 49 (-78.6%)
CWM, LLC
Value ($000) $0 Shares 55 (-69.8%)

Exited Positions (7)

JACOBS LEVY EQUITY MANAGEMENT, INC
Value ($000) $254 Shares 301,012
CITADEL ADVISORS LLC
Value ($000) $215 Shares 254,161
JPMORGAN CHASE & CO
Value ($000) $2 Shares 2,121
Aventura Private Wealth, LLC
Value ($000) $0 Shares 350
SRS Capital Advisors, Inc.
Value ($000) $0 Shares 148
True Wealth Design, LLC
Value ($000) $0 Shares 17
Cloud Capital Management, LLC
Value ($000) $0 Shares 49