Location: San Francisco, CA
CIK: 0001442756 · Show all filings
Period: Q3 2022 (← Previous) (Next →)
Filing Date: Nov 14, 2022
Total Value: $2.764B (94.3% shares, 5.7% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| CYTK | CYTOKINETICS INC | 2,465,016 | $119M | 4.3% | $48.45 | $24.28 | +98.2% | COM NEW | 23282W605 |
| LLY | LILLY ELI & CO | 298,643 | $96.57M | 3.5% | $323.35 * | $156.24 | +97.2% | COM | 532457108 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 1,115,949 | $94.6M | 3.4% | $84.77 * | $84.08 | +5.9% | COM | 09061G101 |
| RCUS | ARCUS BIOSCIENCES INC | 3,383,233 | $88.5M | 3.2% | $26.16 | $22.22 | +19.0% | COM | 03969F109 |
| CNC | CENTENE CORP DEL | 1,112,480 | $86.56M | 3.1% | $77.81 * | $66.53 | +34.3% | COM | 15135B101 |
| HUM | HUMANA INC | 166,066 | $80.57M | 2.9% | $485.19 * | $349.66 | +34.2% | COM | 444859102 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 571,936 | $76.23M | 2.8% | $133.29 * | $145.97 | +4.2% | SHS USD | G50871105 |
| AXSM | AXSOME THERAPEUTICS INC | 1,659,733 | $74.06M | 2.7% | $44.62 * | $34.93 | +43.0% | COM | 05464T104 |
| PEN | PENUMBRA INC | 360,030 | $68.26M | 2.5% | $189.60 * | $191.39 | -16.2% | COM | 70975L107 |
| — | HORIZON THERAPEUTICS PUB L | 1,091,840 | $67.57M | 2.4% | $61.89 | $64.47 | — | SHS | G46188101 |
| CRBU | CARIBOU BIOSCIENCES INC | 6,000,000 | $63.3M | 2.3% | $10.55 * | $19.24 | -51.6% | COM | 142038108 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 493,721 | $61.85M | 2.2% | $125.28 * | $91.74 | +57.4% | COM | 450056106 |
| ERAS | ERASCA INC | 7,264,981 | $56.67M | 2.1% | $7.80 * | $16.12 | -50.0% | COM | 29479A108 |
| UNH | UNITEDHEALTH GROUP INC | 111,554 | $56.34M | 2.0% | $505.04 | $311.60 | +58.9% | COM | 91324P102 |
| PRTA | PROTHENA CORP PLC | 840,238 | $50.94M | 1.8% | $60.63 * | $30.65 | +3.2% | SHS | G72800108 |
| — | SEAGEN INC | 365,215 | $49.97M | 1.8% | $136.83 | $167.84 | — | COM | 81181C104 |
| — | OAK STR HEALTH INC | 63,000,000 | $48.86M | 1.8% | $0.78 | $0.78 | — | NOTE 3/1 | 67181AAB3 |
| MOH | MOLINA HEALTHCARE INC | 143,779 | $47.42M | 1.7% | $329.84 * | $221.27 | +45.5% | COM | 60855R100 |
| — | AERIE PHARMACEUTICALS INC | 48,150,000 | $47.38M | 1.7% | $0.98 | $0.81 | — | NOTE 1.500%10/0 | 00771VAB4 |
| — | BIOMARIN PHARMACEUTICAL INC | 45,910,000 | $45.6M | 1.6% | $0.99 | $1.04 | — | NOTE 0.599% 8/0 | 09061GAH4 |
| XLK | SELECT SECTOR SPDR TR | 383,500 | $45.55M | 1.6% | $118.78 | — | — | Put | 81369Y803 |
| DHR | DANAHER CORPORATION | 175,690 | $45.38M | 1.6% | $258.29 * | $143.93 | +67.2% | COM | 235851102 |
| QURE | UNIQURE NV | 2,393,311 | $44.9M | 1.6% | $18.76 * | $16.59 | +26.7% | SHS | N90064101 |
| BIIB | BIOGEN INC | 166,800 | $44.54M | 1.6% | $267.00 * | $212.38 | 0.0% | Call | 09062X103 |
| CAH | CARDINAL HEALTH INC | 639,783 | $42.66M | 1.5% | $66.68 * | $44.62 | +32.8% | COM | 14149Y108 |
| ABBV | ABBVIE INC | 317,163 | $42.57M | 1.5% | $134.21 * | $132.55 | -4.1% | COM | 00287Y109 |
| IQV | IQVIA HLDGS INC | 229,081 | $41.5M | 1.5% | $181.14 * | $144.71 | +51.4% | COM | 46266C105 |
| AVTR | AVANTOR INC | 2,079,657 | $40.76M | 1.5% | $19.60 * | $23.15 | +15.7% | COM | 05352A100 |
| — | VERVE THERAPEUTICS INC | 1,168,808 | $40.15M | 1.5% | $34.35 | $22.95 | — | COM | 92539P101 |
| — | DYNAVAX TECHNOLOGIES CORP | 3,805,370 | $39.73M | 1.4% | $10.44 | $8.25 | — | COM NEW | 268158201 |
| EW | EDWARDS LIFESCIENCES CORP | 480,256 | $39.68M | 1.4% | $82.63 * | $75.31 | +27.8% | COM | 28176E108 |
| PEN | PENUMBRA INC | 207,500 | $39.34M | 1.4% | $189.60 * | $191.39 | -16.2% | Call | 70975L107 |
| CI | CIGNA CORP NEW | 141,300 | $39.21M | 1.4% | $277.47 * | $226.04 | +17.1% | COM | 125523100 |
| BIIB | BIOGEN INC | 139,326 | $37.2M | 1.3% | $267.00 * | $212.38 | 0.0% | COM | 09062X103 |
| ARGX | ARGENX SE | 104,732 | $36.98M | 1.3% | $353.05 | $378.88 | — | SPONSORED ADR | 04016X101 |
| MCK | MCKESSON CORP | 105,811 | $35.96M | 1.3% | $339.87 | $163.53 | +108.7% | COM | 58155Q103 |
| — | POINT BIOPHARMA GLOBAL INC | 4,515,216 | $34.9M | 1.3% | $7.73 | $7.73 | — | COM | 730541109 |
| VEEV | VEEVA SYS INC | 202,387 | $33.37M | 1.2% | $164.88 * | $184.01 | +8.6% | CL A COM | 922475108 |
| HCA | HCA HEALTHCARE INC | 175,235 | $32.21M | 1.2% | $183.79 * | $193.55 | 0.0% | COM | 40412C101 |
| WAT | WATERS CORP | 117,634 | $31.71M | 1.1% | $269.53 * | $237.41 | +34.5% | COM | 941848103 |
| AZN | ASTRAZENECA PLC | 576,800 | $31.63M | 1.1% | $54.84 | $59.47 | — | SPONSORED ADR | 046353108 |
| TMO | THERMO FISHER SCIENTIFIC INC | 62,143 | $31.52M | 1.1% | $507.19 * | $505.13 | +9.7% | COM | 883556102 |
| MRK | MERCK & CO INC | 360,520 | $31.05M | 1.1% | $86.12 * | $79.21 | +1.5% | COM | 58933Y105 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1,289,073 | $30.98M | 1.1% | $24.03 * | $21.76 | +3.1% | COM | 87164F105 |
| — | KARUNA THERAPEUTICS INC | 130,293 | $29.31M | 1.1% | $224.93 | $120.78 | — | COM | 48576A100 |
| THC | TENET HEALTHCARE CORP | 544,583 | $28.09M | 1.0% | $51.58 * | $30.97 | +91.7% | COM NEW | 88033G407 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 2,162,411 | $27.25M | 1.0% | $12.60 * | $10.32 | +24.8% | COM | 09058V103 |
| — | NEVRO CORP | 563,560 | $26.26M | 1.0% | $46.60 | $110.34 | — | COM | 64157F103 |
| ICLR | ICON PLC | 134,740 | $24.76M | 0.9% | $183.78 * | $192.01 | +13.3% | SHS | G4705A100 |
| ICUI | ICU MED INC | 160,250 | $24.13M | 0.9% | $150.60 * | $183.96 | -9.6% | COM | 44930G107 |
| JNJ | JOHNSON & JOHNSON | 137,746 | $22.5M | 0.8% | $163.36 * | $148.65 | +2.9% | COM | 478160104 |
| PRCT | PROCEPT BIOROBOTICS CORP | 517,526 | $21.46M | 0.8% | $41.46 * | $37.46 | +6.5% | COM | 74276L105 |
| NTLA | INTELLIA THERAPEUTICS INC | 344,868 | $19.3M | 0.7% | $55.96 * | $67.62 | -8.3% | COM | 45826J105 |
| — | OAK STR HEALTH INC | 722,844 | $17.72M | 0.6% | $24.52 | $27.59 | — | COM | 67181A107 |
| — | GENERATION BIO CO | 3,013,712 | $16M | 0.6% | $5.31 | $6.61 | — | COM | 37148K100 |
| EDIT | EDITAS MEDICINE INC | 1,279,054 | $15.66M | 0.6% | $12.24 * | $14.51 | +7.4% | COM | 28106W103 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 180,000 | $15.26M | 0.6% | $84.77 * | $84.08 | +5.9% | Call | 09061G101 |
| MYGN | MYRIAD GENETICS INC | 742,138 | $14.16M | 0.5% | $19.08 * | $28.44 | -19.3% | COM | 62855J104 |
| HOWL | WEREWOLF THERAPEUTICS INC | 2,815,654 | $12.7M | 0.5% | $4.51 * | $6.36 | -14.6% | COM | 95075A107 |
| ELV | ELEVANCE HEALTH INC | 25,800 | $11.72M | 0.4% | $454.22 | $397.15 | +14.6% | COM | 036752103 |
| — | OUTSET MED INC | 729,413 | $11.62M | 0.4% | $15.93 | $15.93 | — | COM | 690145107 |
| — | ITEOS THERAPEUTICS INC | 537,954 | $10.25M | 0.4% | $19.05 | $20.60 | — | COM | 46565G104 |
| PMVP | PMV PHARMACEUTICALS INC | 855,164 | $10.18M | 0.4% | $11.90 * | $19.43 | -25.6% | COM | 69353Y103 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 9,320,584 | $10.02M | 0.4% | $1.08 | $2.66 | — | SPONDS ADR | 00653A107 |
| — | JOUNCE THERAPEUTICS INC | 4,094,488 | $9.581M | 0.3% | $2.34 | $9.53 | — | COM | 481116101 |
| — | BLUEPRINT MEDICINES CORP | 130,366 | $8.59M | 0.3% | $65.89 | $65.89 | — | COM | 09627Y109 |
| — | NEVRO CORP | 9,000,000 | $8.519M | 0.3% | $0.95 | $0.95 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| APLS | APELLIS PHARMACEUTICALS INC | 121,880 | $8.324M | 0.3% | $68.30 * | $59.17 | 0.0% | COM | 03753U106 |
| — | PRAXIS PRECISION MEDICINES I | 3,458,525 | $7.851M | 0.3% | $2.27 | $5.94 | — | COM | 74006W108 |
| — | CANO HEALTH INC | 776,893 | $6.736M | 0.2% | $8.67 | $8.67 | — | COM CL A | 13781Y103 |
| — | DYNAVAX TECHNOLOGIES CORP | 5,000,000 | $6.328M | 0.2% | $1.27 | $1.50 | — | NOTE 2.500% 5/1 | 268158AD4 |
| IOBT | IO BIOTECH INC | 2,159,155 | $5.851M | 0.2% | $2.71 * | $8.35 | -55.6% | COM | 449778109 |
| PRTA | PROTHENA CORP PLC | 80,500 | $4.881M | 0.2% | $60.63 * | $30.65 | +3.2% | Call | G72800108 |
| — | BCLS ACQUISITION CORP | 464,103 | $4.65M | 0.2% | $10.02 | $11.03 | — | COM CL A | G0904B105 |
| — | JIYA ACQUISITION CORP | 464,103 | $4.627M | 0.2% | $9.97 | $10.30 | — | COM CL A | 47760M102 |
| — | IVERIC BIO INC | 256,284 | $4.598M | 0.2% | $17.94 | $16.24 | — | COM | 46583P102 |
| CMPS | COMPASS PATHWAYS PLC | 397,711 | $4.267M | 0.2% | $10.73 | $10.82 | — | SPONSORED ADS | 20451W101 |
| SANA | SANA BIOTECHNOLOGY INC | 691,464 | $4.149M | 0.2% | $6.00 * | $7.01 | +2.9% | COM | 799566104 |
| LUNG | PULMONX CORP | 199,703 | $3.327M | 0.1% | $16.66 * | $18.41 | 0.0% | COM | 745848101 |
| — | ESSA PHARMA INC | 1,478,252 | $2.69M | 0.1% | $1.82 | $2.68 | — | COM NEW | 29668H708 |
| SOPH | SOPHIA GENETICS SA | 879,913 | $2.314M | 0.1% | $2.63 * | $17.39 | -79.8% | ORDINARY SHARES | H82027105 |
| SGHT | SIGHT SCIENCES INC | 227,692 | $1.446M | 0.1% | $6.35 * | $8.80 | -3.9% | COM | 82657M105 |
| CELC | CELCUITY INC | 140,426 | $1.41M | 0.1% | $10.04 * | $9.44 | 0.0% | COM | 15102K100 |
| ZLAB | ZAI LAB LTD | 23,612 | $808K | 0.0% | $34.22 | $34.22 | — | ADR | 98887Q104 |
| — | PARDES BIOSCIENCES INC | 285,170 | $528K | 0.0% | $1.85 | $10.98 | — | COM | 69945Q105 |