Location: San Francisco, CA
CIK: 0001442756 · Show all filings
Period: Q4 2022 (← Previous) (Next →)
Filing Date: Feb 14, 2023
Total Value: $2.793B (96.3% shares, 3.7% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | HORIZON THERAPEUTICS PUB L | 1,091,840 | $124M | 4.4% | $113.80 | $64.47 | — | SHS | G46188101 |
| CYTK | CYTOKINETICS INC | 2,399,545 | $110M | 3.9% | $45.82 * | $24.28 | +76.9% | COM NEW | 23282W605 |
| LLY | LILLY ELI & CO | 298,643 | $109M | 3.9% | $365.84 * | $156.24 | +121.3% | COM | 532457108 |
| MRK | MERCK & CO INC | 871,500 | $96.69M | 3.5% | $110.95 * | $79.47 | +16.8% | Call | 58933Y105 |
| CNC | CENTENE CORP DEL | 1,112,480 | $91.23M | 3.3% | $82.01 | $66.53 | +22.8% | COM | 15135B101 |
| HUM | HUMANA INC | 166,066 | $85.06M | 3.0% | $512.19 | $349.66 | +45.3% | COM | 444859102 |
| AXSM | AXSOME THERAPEUTICS INC | 1,092,831 | $84.29M | 3.0% | $77.13 * | $34.93 | +71.1% | COM | 05464T104 |
| PEN | PENUMBRA INC | 360,030 | $80.09M | 2.9% | $222.46 * | $191.39 | +2.2% | COM | 70975L107 |
| JNJ | JOHNSON & JOHNSON | 450,000 | $79.49M | 2.8% | $176.65 * | $148.65 | +5.7% | Put | 478160104 |
| UNH | UNITEDHEALTH GROUP INC | 116,067 | $61.54M | 2.2% | $530.18 * | $318.94 | +56.9% | COM | 91324P102 |
| RCUS | ARCUS BIOSCIENCES INC | 2,703,287 | $55.9M | 2.0% | $20.68 * | $22.22 | +23.9% | COM | 03969F109 |
| ABBV | ABBVIE INC | 329,344 | $53.23M | 1.9% | $161.61 * | $132.72 | +3.4% | COM | 00287Y109 |
| — | LABORATORY CORP AMER HLDGS | 225,000 | $52.98M | 1.9% | $235.48 | $235.48 | — | Call | 50540R409 |
| PEN | PENUMBRA INC | 237,500 | $52.83M | 1.9% | $222.46 * | $191.39 | +2.2% | Call | 70975L107 |
| PRTA | PROTHENA CORP PLC | 875,464 | $52.75M | 1.9% | $60.25 * | $31.77 | +84.3% | SHS | G72800108 |
| QURE | UNIQURE NV | 2,302,314 | $52.19M | 1.9% | $22.67 * | $16.59 | +30.0% | SHS | N90064101 |
| CAH | CARDINAL HEALTH INC | 639,783 | $49.18M | 1.8% | $76.87 * | $44.62 | +60.4% | COM | 14149Y108 |
| — | OAK STR HEALTH INC | 63,000,000 | $48M | 1.7% | $0.76 | $0.78 | — | NOTE 3/1 | 67181AAB3 |
| MOH | MOLINA HEALTHCARE INC | 143,779 | $47.48M | 1.7% | $330.22 * | $221.27 | +53.5% | COM | 60855R100 |
| IQV | IQVIA HLDGS INC | 229,081 | $46.94M | 1.7% | $204.89 | $144.71 | +40.2% | COM | 46266C105 |
| CI | CIGNA CORP NEW | 141,300 | $46.82M | 1.7% | $331.34 * | $226.04 | +32.2% | COM | 125523100 |
| DHR | DANAHER CORPORATION | 175,690 | $46.63M | 1.7% | $265.42 * | $143.93 | +58.5% | COM | 235851102 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 493,721 | $46.25M | 1.7% | $93.67 * | $91.74 | +18.6% | COM | 450056106 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1,814,634 | $46.18M | 1.7% | $25.45 * | $22.22 | +5.0% | COM | 87164F105 |
| BIIB | BIOGEN INC | 155,659 | $43.11M | 1.5% | $276.92 | $219.73 | +28.5% | COM | 09062X103 |
| MRK | MERCK & CO INC | 367,634 | $40.79M | 1.5% | $110.95 * | $79.47 | +16.8% | COM | 58933Y105 |
| — | DYNAVAX TECHNOLOGIES CORP | 3,805,370 | $40.49M | 1.4% | $10.64 | $8.25 | — | COM NEW | 268158201 |
| MCK | MCKESSON CORP | 105,811 | $39.69M | 1.4% | $375.12 * | $163.53 | +124.5% | COM | 58155Q103 |
| ARGX | ARGENX SE | 104,732 | $39.68M | 1.4% | $378.83 | $378.88 | — | SPONSORED ADR | 04016X101 |
| EW | EDWARDS LIFESCIENCES CORP | 530,030 | $39.55M | 1.4% | $74.61 * | $75.48 | +2.1% | COM | 28176E108 |
| AZN | ASTRAZENECA PLC | 576,800 | $39.11M | 1.4% | $67.80 | $59.47 | — | SPONSORED ADR | 046353108 |
| — | BIOMARIN PHARMACEUTICAL INC | 35,910,000 | $38.2M | 1.4% | $1.06 | $1.04 | — | NOTE 0.599% 8/0 | 09061GAH4 |
| UNH | UNITEDHEALTH GROUP INC | 69,600 | $36.9M | 1.3% | $530.18 * | $318.94 | +56.9% | Call | 91324P102 |
| ELV | ELEVANCE HEALTH INC | 67,115 | $34.43M | 1.2% | $512.97 * | $450.89 | +7.4% | COM | 036752103 |
| TMO | THERMO FISHER SCIENTIFIC INC | 62,143 | $34.22M | 1.2% | $550.69 * | $505.13 | +3.9% | COM | 883556102 |
| AVTR | AVANTOR INC | 1,607,612 | $33.9M | 1.2% | $21.09 | $23.15 | -10.6% | COM | 05352A100 |
| — | POINT BIOPHARMA GLOBAL INC | 4,633,802 | $33.78M | 1.2% | $7.29 | $7.72 | — | COM | 730541109 |
| WAT | WATERS CORP | 94,624 | $32.42M | 1.2% | $342.58 * | $237.41 | +33.3% | COM | 941848103 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 310,401 | $32.12M | 1.2% | $103.49 * | $84.08 | +11.7% | COM | 09061G101 |
| ISRG | INTUITIVE SURGICAL INC | 114,450 | $30.37M | 1.1% | $265.35 * | $243.83 | 0.0% | COM NEW | 46120E602 |
| CRBU | CARIBOU BIOSCIENCES INC | 4,459,783 | $28.01M | 1.0% | $6.28 * | $19.24 | -53.7% | COM | 142038108 |
| A | AGILENT TECHNOLOGIES INC | 183,504 | $27.46M | 1.0% | $149.65 * | $139.69 | 0.0% | COM | 00846U101 |
| — | KARUNA THERAPEUTICS INC | 130,293 | $25.6M | 0.9% | $196.50 | $120.78 | — | COM | 48576A100 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 243,000 | $25.15M | 0.9% | $103.49 * | $84.08 | +11.7% | Call | 09061G101 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 2,162,411 | $24.82M | 0.9% | $11.48 * | $10.32 | +20.9% | COM | 09058V103 |
| — | SEAGEN INC | 192,384 | $24.72M | 0.9% | $128.51 | $167.84 | — | COM | 81181C104 |
| JNJ | JOHNSON & JOHNSON | 137,746 | $24.33M | 0.9% | $176.65 * | $148.65 | +5.7% | COM | 478160104 |
| AXSM | AXSOME THERAPEUTICS INC | 299,000 | $23.06M | 0.8% | $77.13 * | $34.93 | +71.1% | Call | 05464T104 |
| HCA | HCA HEALTHCARE INC | 91,945 | $22.06M | 0.8% | $239.96 * | $193.55 | +12.7% | COM | 40412C101 |
| PRCT | PROCEPT BIOROBOTICS CORP | 517,526 | $21.5M | 0.8% | $41.54 * | $37.46 | +14.6% | COM | 74276L105 |
| ERAS | ERASCA INC | 4,797,460 | $20.68M | 0.7% | $4.31 * | $16.12 | -57.9% | COM | 29479A108 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 128,500 | $20.47M | 0.7% | $159.31 * | $145.97 | +0.4% | Put | G50871105 |
| — | IVERIC BIO INC | 917,557 | $19.64M | 0.7% | $21.41 | $19.97 | — | COM | 46583P102 |
| ACLX | ARCELLX INC | 616,515 | $19.1M | 0.7% | $30.98 * | $22.94 | 0.0% | COMMON STOCK | 03940C100 |
| UHS | UNIVERSAL HLTH SVCS INC | 124,421 | $17.53M | 0.6% | $140.89 * | $116.28 | 0.0% | CL B | 913903100 |
| APLS | APELLIS PHARMACEUTICALS INC | 318,422 | $16.47M | 0.6% | $51.71 * | $55.39 | -4.2% | COM | 03753U106 |
| ABBV | ABBVIE INC | 100,000 | $16.16M | 0.6% | $161.61 * | $132.72 | +3.4% | Call | 00287Y109 |
| — | NEVRO CORP | 17,500,000 | $16.06M | 0.6% | $0.92 | $0.93 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| ICLR | ICON PLC | 81,725 | $15.88M | 0.6% | $194.25 * | $192.01 | +3.3% | SHS | G4705A100 |
| CRL | CHARLES RIV LABS INTL INC | 72,820 | $15.87M | 0.6% | $217.90 | $218.37 | 0.0% | COM | 159864107 |
| DXCM | DEXCOM INC | 135,465 | $15.34M | 0.5% | $113.24 * | $109.79 | 0.0% | COM | 252131107 |
| EDIT | EDITAS MEDICINE INC | 1,466,732 | $13.01M | 0.5% | $8.87 * | $14.06 | -21.9% | COM | 28106W103 |
| THC | TENET HEALTHCARE CORP | 254,525 | $12.42M | 0.4% | $48.79 * | $30.97 | +49.3% | COM NEW | 88033G407 |
| LUNG | PULMONX CORP | 1,455,770 | $12.27M | 0.4% | $8.43 * | $10.73 | -11.4% | COM | 745848101 |
| — | OAK STR HEALTH INC | 565,239 | $12.16M | 0.4% | $21.51 | $27.59 | — | COM | 67181A107 |
| — | GENERATION BIO CO | 2,903,192 | $11.41M | 0.4% | $3.93 | $6.61 | — | COM | 37148K100 |
| THC | TENET HEALTHCARE CORP | 225,900 | $11.02M | 0.4% | $48.79 * | $30.97 | +49.3% | Call | 88033G407 |
| CELC | CELCUITY INC | 712,111 | $9.977M | 0.4% | $14.01 * | $10.08 | +1.6% | COM | 15102K100 |
| — | ESSA PHARMA INC | 3,844,332 | $9.688M | 0.3% | $2.52 | $2.58 | — | COM NEW | 29668H708 |
| PRTA | PROTHENA CORP PLC | 152,300 | $9.176M | 0.3% | $60.25 * | $31.77 | +84.3% | Call | G72800108 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 4,843,510 | $7.072M | 0.3% | $1.46 | $2.66 | — | SPONDS ADR | 00653A107 |
| — | PRAXIS PRECISION MEDICINES I | 2,777,467 | $6.61M | 0.2% | $2.38 | $5.94 | — | COM | 74006W108 |
| — | BLUEPRINT MEDICINES CORP | 130,366 | $5.711M | 0.2% | $43.81 | $65.89 | — | COM | 09627Y109 |
| — | VERVE THERAPEUTICS INC | 217,302 | $4.205M | 0.2% | $19.35 | $22.95 | — | COM | 92539P101 |
| CMPS | COMPASS PATHWAYS PLC | 509,625 | $4.092M | 0.1% | $8.03 | $10.21 | — | SPONSORED ADS | 20451W101 |
| — | LABORATORY CORP AMER HLDGS | 13,561 | $3.193M | 0.1% | $235.48 | $235.48 | — | COM NEW | 50540R409 |
| PMVP | PMV PHARMACEUTICALS INC | 333,716 | $2.903M | 0.1% | $8.70 * | $19.43 | -45.1% | COM | 69353Y103 |
| HOWL | WEREWOLF THERAPEUTICS INC | 1,293,293 | $2.651M | 0.1% | $2.05 * | $6.36 | -58.8% | COM | 95075A107 |
| — | BLUEBIRD BIO INC | 244,867 | $1.694M | 0.1% | $6.92 | $6.92 | — | COM | 09609G100 |
| — | ITEOS THERAPEUTICS INC | 70,922 | $1.385M | 0.0% | $19.53 | $20.60 | — | COM | 46565G104 |
| IOBT | IO BIOTECH INC | 507,640 | $1.168M | 0.0% | $2.30 * | $8.35 | -68.3% | COM | 449778109 |
| KROS | KEROS THERAPEUTICS INC | 15,999 | $768K | 0.0% | $48.02 * | $46.71 | 0.0% | COM | 492327101 |
| XENE | XENON PHARMACEUTICALS INC | 17,488 | $690K | 0.0% | $39.43 * | $36.42 | 0.0% | COM | 98420N105 |
| — | BELLUS HEALTH INC NEW | 63,864 | $525K | 0.0% | $8.22 | $8.22 | — | COM NEW | 07987C204 |
| — | JOUNCE THERAPEUTICS INC | 345,926 | $384K | 0.0% | $1.11 | $9.53 | — | COM | 481116101 |
| SANA | SANA BIOTECHNOLOGY INC | 62,776 | $248K | 0.0% | $3.95 * | $7.01 | -30.2% | COM | 799566104 |
| — | VECTIVBIO HLDG AG | 25,541 | $221K | 0.0% | $8.67 | $8.67 | — | ORD SHS | H9060V101 |
| BHVN | BIOHAVEN LTD | 10,988 | $153K | 0.0% | $13.88 | $14.12 | 0.0% | COM | G1110E107 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 13,337 | $85,223 | 0.0% | $6.39 * | $7.81 | 0.0% | COM | 462260100 |