Location: Larkspur, CA
CIK: 0001425738 · Show all filings
Period: Q1 2023 (← Previous) (Next →)
Filing Date: May 15, 2023
Total Value: $2.305B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 18,346,861 | $203M | 8.8% | $11.09 * | $10.66 | +15.7% | COM | 03152W109 |
| KRYS | KRYSTAL BIOTECH INC | 1,913,280 | $153M | 6.6% | $80.06 | $43.92 | +78.9% | COM | 501147102 |
| — | IVERIC BIO INC | 4,205,206 | $102M | 4.4% | $24.33 | $18.33 | — | COM | 46583P102 |
| — | DECIPHERA PHARMACEUTICALS IN | 5,582,105 | $86.24M | 3.7% | $15.45 | $17.91 | — | COM | 24344T101 |
| — | AKERO THERAPEUTICS INC | 2,044,389 | $78.22M | 3.4% | $38.26 | $38.86 | — | COM | 00973Y108 |
| PLRX | PLIANT THERAPEUTICS INC | 2,925,648 | $77.82M | 3.4% | $26.60 * | $24.18 | +17.8% | COM | 729139105 |
| FATE | FATE THERAPEUTICS INC | 12,957,222 | $73.86M | 3.2% | $5.70 * | $13.22 | -54.4% | COM | 31189P102 |
| KYMR | KYMERA THERAPEUTICS INC | 2,410,769 | $71.43M | 3.1% | $29.63 * | $32.56 | -0.9% | COM | 501575104 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,879,739 | $67.63M | 2.9% | $35.98 * | $11.60 | +272.1% | COM NEW | 15117B202 |
| REPL | REPLIMUNE GROUP INC | 3,811,988 | $67.32M | 2.9% | $17.66 * | $21.66 | +9.8% | COM | 76029N106 |
| ZYME | ZYMEWORKS INC | 6,067,918 | $54.85M | 2.4% | $9.04 * | $7.03 | +24.1% | COM | 98985Y108 |
| PEN | PENUMBRA INC | 187,992 | $52.39M | 2.3% | $278.69 * | $167.26 | +52.6% | COM | 70975L107 |
| LIVN | LIVANOVA PLC | 1,186,418 | $51.7M | 2.2% | $43.58 * | $74.93 | -32.4% | SHS | G5509L101 |
| BEAM | BEAM THERAPEUTICS INC | 1,612,094 | $49.36M | 2.1% | $30.62 * | $25.01 | +57.8% | COM | 07373V105 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 335,159 | $49.04M | 2.1% | $146.33 | $150.38 | -1.6% | SHS USD | G50871105 |
| ARGX | ARGENX SE | 130,540 | $48.64M | 2.1% | $372.58 | $87.46 | — | SPONSORED ADR | 04016X101 |
| XENE | XENON PHARMACEUTICALS INC | 1,325,832 | $47.45M | 2.1% | $35.79 * | $32.01 | +15.4% | COM | 98420N105 |
| — | IGM BIOSCIENCES INC | 3,334,355 | $45.81M | 2.0% | $13.74 | $22.36 | — | COM | 449585108 |
| — | OAK STR HEALTH INC | 1,061,295 | $41.05M | 1.8% | $38.68 | $42.24 | — | COM | 67181A107 |
| — | CATALENT INC | 610,304 | $40.1M | 1.7% | $65.71 | $65.71 | — | COM | 148806102 |
| DXCM | DEXCOM INC | 336,048 | $39.04M | 1.7% | $116.18 * | $111.94 | 0.0% | COM | 252131107 |
| SYK | STRYKER CORPORATION | 136,464 | $38.96M | 1.7% | $285.47 * | $215.28 | +19.7% | COM | 863667101 |
| STOK | STOKE THERAPEUTICS INC | 4,145,396 | $34.53M | 1.5% | $8.33 * | $11.74 | -23.1% | COM | 86150R107 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 335,170 | $32.59M | 1.4% | $97.24 * | $103.67 | 0.0% | COM | 09061G101 |
| SRPT | SAREPTA THERAPEUTICS INC | 231,595 | $31.92M | 1.4% | $137.83 * | $129.72 | 0.0% | COM | 803607100 |
| BMY | BRISTOL-MYERS SQUIBB CO | 449,442 | $31.15M | 1.4% | $69.31 * | $61.50 | 0.0% | COM | 110122108 |
| RGNX | REGENXBIO INC | 1,640,725 | $31.03M | 1.3% | $18.91 * | $33.26 | -33.5% | COM | 75901B107 |
| — | IMMUNOGEN INC | 8,046,217 | $30.9M | 1.3% | $3.84 | $5.30 | — | COM | 45253H101 |
| ELV | ELEVANCE HEALTH INC | 66,398 | $30.53M | 1.3% | $459.81 | $362.14 | +25.7% | COM | 036752103 |
| VTYX | VENTYX BIOSCIENCES INC | 815,774 | $27.33M | 1.2% | $33.50 * | $22.14 | +75.6% | COM | 92332V107 |
| TRDA | ENTRADA THERAPEUTICS INC | 1,831,608 | $26.56M | 1.2% | $14.50 | $17.12 | — | COM | 29384C108 |
| ADCT | ADC THERAPEUTICS SA | 13,565,249 | $26.45M | 1.1% | $1.95 * | $22.19 | -83.4% | SHS | H0036K147 |
| HUM | HUMANA INC | 52,079 | $25.28M | 1.1% | $485.46 | $478.45 | 0.0% | COM | 444859102 |
| — | AUGMEDIX INC | 14,380,327 | $25.02M | 1.1% | $1.74 | $3.15 | — | COM | 05105P107 |
| SRRK | SCHOLAR ROCK HLDG CORP | 3,124,226 | $24.99M | 1.1% | $8.00 * | $14.52 | -30.2% | COM | 80706P103 |
| — | REPARE THERAPEUTICS INC | 2,533,050 | $24.93M | 1.1% | $9.84 | $30.51 | — | COM | 760273102 |
| PRME | PRIME MEDICINE INC | 1,992,843 | $24.51M | 1.1% | $12.30 * | $18.06 | -9.8% | COM | 74168J101 |
| NRIX | NURIX THERAPEUTICS INC | 2,749,384 | $24.41M | 1.1% | $8.88 * | $27.39 | -62.0% | COM | 67080M103 |
| STVN | STEVANATO GROUP S P A | 901,932 | $23.36M | 1.0% | $25.90 * | $23.29 | -8.6% | ORD SHS | T9224W109 |
| CRL | CHARLES RIV LABS INTL INC | 115,328 | $23.28M | 1.0% | $201.82 * | $226.63 | 0.0% | COM | 159864107 |
| IMVT | IMMUNOVANT INC | 1,317,031 | $20.43M | 0.9% | $15.51 * | $13.42 | +29.3% | COM | 45258J102 |
| — | GRITSTONE BIO INC | 6,926,926 | $19.26M | 0.8% | $2.78 | $8.41 | — | COM | 39868T105 |
| CNC | CENTENE CORP DEL | 277,351 | $17.53M | 0.8% | $63.21 * | $77.15 | -8.0% | COM | 15135B101 |
| STTK | SHATTUCK LABS INC | 5,619,914 | $16.52M | 0.7% | $2.94 * | $32.14 | -89.0% | COM | 82024L103 |
| — | ATARA BIOTHERAPEUTICS INC | 5,612,056 | $16.27M | 0.7% | $2.90 | $23.37 | — | COM | 046513107 |
| — | VERVE THERAPEUTICS INC | 1,120,679 | $16.16M | 0.7% | $14.42 | $57.66 | — | COM | 92539P101 |
| IQV | IQVIA HLDGS INC | 71,657 | $14.25M | 0.6% | $198.89 * | $213.73 | 0.0% | COM | 46266C105 |
| ABSI | ABSCI CORPORATION | 8,031,094 | $14.05M | 0.6% | $1.75 * | $19.41 | -87.5% | COM | 00091E109 |
| — | 89BIO INC | 900,000 | $13.71M | 0.6% | $15.23 | $15.23 | — | COM | 282559103 |
| ANNX | ANNEXON INC | 3,503,190 | $13.49M | 0.6% | $3.85 * | $21.71 | -74.7% | COM | 03589W102 |
| — | RAPT THERAPEUTICS INC | 688,132 | $12.63M | 0.5% | $18.35 | $21.67 | — | COM | 75382E109 |
| — | ALLAKOS INC | 2,286,177 | $10.17M | 0.4% | $4.45 | $50.94 | — | COM | 01671P100 |
| — | MEDAVAIL HOLDINGS INC | 34,604,516 | $9.918M | 0.4% | $0.29 | $5.65 | — | COM | 58406B103 |
| BSX | BOSTON SCIENTIFIC CORP | 171,780 | $8.594M | 0.4% | $50.03 * | $47.13 | 0.0% | COM | 101137107 |
| ILMN | ILLUMINA INC | 33,496 | $7.789M | 0.3% | $232.55 * | $204.65 | 0.0% | COM | 452327109 |
| — | ALLOVIR INC | 1,907,969 | $7.517M | 0.3% | $3.94 | $16.35 | — | COM | 019818103 |
| — | SCIENCE 37 HOLDINGS INC | 19,808,234 | $5.578M | 0.2% | $0.28 | $12.47 | — | COM | 808644108 |
| GRFS | GRIFOLS S A | 720,784 | $5.312M | 0.2% | $7.37 | $7.88 | — | SP ADR REP B NVT | 398438408 |
| NUVB | NUVATION BIO INC | 3,031,009 | $5.031M | 0.2% | $1.66 * | $11.18 | -81.9% | COM CL A | 67080N101 |
| — | SOMALOGIC INC | 1,870,839 | $4.771M | 0.2% | $2.55 | $10.41 | — | CLASS A COM | 83444K105 |
| — | LAVA THERAPEUTICS NV | 2,074,372 | $3.443M | 0.1% | $1.66 | $15.19 | — | SHS | N51517105 |
| — | INVITAE CORP | 2,280,403 | $3.079M | 0.1% | $1.35 | $39.75 | — | COM | 46185L103 |
| STXS | STEREOTAXIS INC | 1,487,495 | $3.034M | 0.1% | $2.04 * | $3.05 | -26.3% | COM NEW | 85916J409 |
| ALXO | ALX ONCOLOGY HLDGS INC | 586,977 | $2.653M | 0.1% | $4.52 * | $51.82 | -85.4% | COM | 00166B105 |
| CABA | CABALETTA BIO INC | 274,252 | $2.268M | 0.1% | $8.27 * | $11.85 | -21.0% | COM | 12674W109 |
| — | HOOKIPA PHARMA INC | 2,552,949 | $1.879M | 0.1% | $0.74 | $4.06 | — | COM | 43906K100 |
| IVVD | INVIVYD INC | 1,440,725 | $1.729M | 0.1% | $1.20 * | $37.11 | -95.1% | COM | 00534A102 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 1,046,587 | $1.706M | 0.1% | $1.63 * | $2.16 | -42.0% | COM | 98422E103 |
| — | ACHILLES THERAPEUTICS PLC | 1,608,089 | $1.54M | 0.1% | $0.96 | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | NEOLEUKIN THERAPEUTICS INC | 1,847,600 | $1.293M | 0.1% | $0.70 | $11.83 | — | COM | 64049K104 |
| TKNO | ALPHA TEKNOVA INC | 373,244 | $1.105M | 0.0% | $2.96 * | $25.30 | -80.2% | COM | 02080L102 |
| — | SONENDO INC | 498,131 | $996K | 0.0% | $2.00 | $5.76 | — | COM | 835431107 |
| — | TCR2 THERAPEUTICS INC | 658,336 | $988K | 0.0% | $1.50 | $17.10 | — | COM | 87808K106 |
| CTSO | CYTOSORBENTS CORP | 181,639 | $612K | 0.0% | $3.37 * | $9.04 | -66.8% | COM NEW | 23283X206 |
| — | ATRECA INC | 442,653 | $505K | 0.0% | $1.14 | $15.87 | — | CL A COM | 04965G109 |
| TOI | THE ONCOLOGY INSTITUTE INC | 318,082 | $216K | 0.0% | $0.68 * | $8.92 | -85.7% | COM | 68236X100 |