PFM Health Sciences, LP Quant / Systematic

Location: SAN FRANCISCO, CA

CIK: 0001442756 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 15, 2026

Total Value: $1.097B (98.5% shares, 1.5% debt)

Holdings (83)

New Positions (25)

XBI SPDR SERIES TRUST 5.3%
Value $58.16M Shares 455,300 Est. Cost Unrealized
XLV SELECT SECTOR SPDR TR 3.2%
Value $35.03M Shares 238,900 Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 2.5%
Value $27.22M Shares 45,900 Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 1.7%
Value $18.8M Shares 31,700 Est. Cost Unrealized
INDV INDIVIOR PHARMACEUTICALS INC 1.6%
Value $17.52M Shares 574,666 Est. Cost Unrealized
ABT ABBOTT LABORATORIES 1.3%
Value $14.42M Shares 140,432 Est. Cost Unrealized
ACHC ACADIA HEALTHCARE COMPANY IN 1.2%
Value $13.63M Shares 582,745 Est. Cost Unrealized
NTRA NATERA INC 1.1%
Value $12M Shares 60,004 Est. Cost Unrealized
HSIC SCHEIN HENRY INC 1.0%
Value $11.28M Shares 153,114 Est. Cost Unrealized
MMSI MERIT MED SYS INC 1.0%
Value $11.2M Shares 162,469 Est. Cost Unrealized
TERN TERNS PHARMACEUTICALS INC 0.8%
Value $9.119M Shares 172,962 Est. Cost Unrealized
ORKA ORUKA THERAPEUTICS INC 0.8%
Value $8.537M Shares 174,052 Est. Cost Unrealized
TNGX TANGO THERAPEUTICS INC 0.8%
Value $8.499M Shares 406,245 Est. Cost Unrealized
NVO NOVO-NORDISK A S 0.7%
Value $7.246M Shares 197,181 Est. Cost Unrealized
ALHC ALIGNMENT HEALTHCARE INC 0.6%
Value $6.34M Shares 359,826 Est. Cost Unrealized
ROIV ROIVANT SCIENCES LTD 0.5%
Value $5.746M Shares 207,446 Est. Cost Unrealized
ASND ASCENDIS PHARMA A/S 0.5%
Value $5.124M Shares 22,400 Est. Cost Unrealized
KOD KODIAK SCIENCES INC 0.4%
Value $4.373M Shares 114,719 Est. Cost Unrealized
ARWR ARROWHEAD PHARMACEUTICALS IN 0.4%
Value $4.03M Shares 64,279 Est. Cost Unrealized
EPRX EUPRAXIA PHARMACEUTICALS INC 0.4%
Value $3.916M Shares 540,871 Est. Cost Unrealized
DFTX DEFINIUM THERAPEUTICS INC 0.4%
Value $3.88M Shares 205,317 Est. Cost Unrealized
CAPR CAPRICOR THERAPEUTICS INC 0.3%
Value $3.764M Shares 123,831 Est. Cost Unrealized
ILMN ILLUMINA INC 0.3%
Value $3.558M Shares 28,869 Est. Cost Unrealized
HCA HCA HEALTHCARE INC 0.2%
Value $2.177M Shares 4,600 Est. Cost Unrealized
GMED GLOBUS MED INC 0.1%
Value $1.458M Shares 16,923 Est. Cost Unrealized

Increased Positions (32)

JAZZ JAZZ PHARMACEUTICALS PLC 3.1%
Value $33.68M (+292.2%) Shares 178,144 (+252.7%) Est. Cost Unrealized
MDGL MADRIGAL PHARMACEUTICALS INC 1.6%
Value $17.87M (+322.9%) Shares 34,146 (+370.5%) Est. Cost Unrealized
DNTH DIANTHUS THERAPEUTICS INC 1.3%
Value $14.45M (+252.0%) Shares 172,137 (+72.9%) Est. Cost Unrealized
RYTM RHYTHM PHARMACEUTICALS INC 1.1%
Value $11.88M (+176.1%) Shares 136,621 (+239.8%) Est. Cost Unrealized
CLDX CELLDEX THERAPEUTICS INC NEW 0.9%
Value $10.31M (+185.0%) Shares 324,957 (+144.0%) Est. Cost Unrealized
NEO NEOGENOMICS INC 1.2%
Value $13.24M (-33.5%) Shares 1,784,552 (+5.3%) Est. Cost Unrealized
BLTE BELITE BIO INC 0.9%
Value $9.476M (+198.8%) Shares 59,432 (+199.8%) Est. Cost Unrealized
NBIX NEUROCRINE BIOSCIENCES INC 2.6%
Value $28.41M (+22.8%) Shares 215,678 (+32.2%) Est. Cost Unrealized
CGON CG ONCOLOGY INC 1.0%
Value $11.23M (+65.0%) Shares 165,925 (+1.2%) Est. Cost Unrealized
COO COOPER COS INC 1.1%
Value $12.14M (+47.0%) Shares 169,829 (+68.5%) Est. Cost Unrealized
BTSG BRIGHTSPRING HEALTH SVCS INC 0.7%
Value $7.982M (+79.8%) Shares 187,335 (+58.1%) Est. Cost Unrealized
ITGR INTEGER HLDGS CORP 1.1%
Value $11.89M (+42.2%) Shares 135,081 (+26.7%) Est. Cost Unrealized
TARS TARSUS PHARMACEUTICALS INC 0.5%
Value $5.628M (+151.4%) Shares 80,226 (+193.5%) Est. Cost Unrealized
PRAX PRAXIS PRECISION MEDICINES I 1.0%
Value $11.42M (+24.3%) Shares 35,438 (+13.7%) Est. Cost Unrealized
CMPS COMPASS PATHWAYS PLC 0.7%
Value $7.56M (+40.5%) Shares 1,367,099 (+75.4%) Est. Cost Unrealized
MLYS MINERALYS THERAPEUTICS INC 0.4%
Value $3.865M (+123.6%) Shares 142,677 (+199.5%) Est. Cost Unrealized
VKTX VIKING THERAPEUTICS INC 0.8%
Value $8.561M (+28.8%) Shares 263,106 (+39.2%) Est. Cost Unrealized
ASCENDIS PHARMA A/S 1.5%
Value $16.92M (+11.8%) Shares 11,505,000 (+8.0%) Est. Cost Unrealized
VERA VERA THERAPEUTICS INC 0.6%
Value $7.035M (+29.0%) Shares 174,867 (+62.4%) Est. Cost Unrealized
GPCR STRUCTURE THERAPEUTICS INC 0.6%
Value $6.092M (+28.3%) Shares 126,383 (+85.2%) Est. Cost Unrealized
AXSM AXSOME THERAPEUTICS INC. 4.1%
Value $44.67M (-2.8%) Shares 264,304 (+5.1%) Est. Cost Unrealized
UNH UNITEDHEALTH GROUP INC 1.4%
Value $15.7M (-5.9%) Shares 58,038 (+14.8%) Est. Cost Unrealized
PSNL PERSONALIS INC 0.5%
Value $5.543M (-13.6%) Shares 870,097 (+8.0%) Est. Cost Unrealized
EW EDWARDS LIFESCIENCES CORP 1.9%
Value $20.38M (-3.1%) Shares 254,510 (+3.1%) Est. Cost Unrealized
TECX TECTONIC THERAPEUTIC INC 0.1%
Value $1.426M (+60.0%) Shares 46,129 (+8.0%) Est. Cost Unrealized
GKOS GLAUKOS CORP 2.1%
Value $23.22M (+2.0%) Shares 215,685 (+6.9%) Est. Cost Unrealized
INBX INHIBRX BIOSCIENCES INC 1.9%
Value $20.53M (-2.1%) Shares 305,431 (+15.0%) Est. Cost Unrealized
AMLX AMYLYX PHARMACEUTICALS INC 0.2%
Value $2.019M (+24.2%) Shares 145,275 (+8.0%) Est. Cost Unrealized
OM OUTSET MED INC 0.2%
Value $2.283M (+16.0%) Shares 594,630 (+12.0%) Est. Cost Unrealized
MDLN MEDLINE INC 0.4%
Value $3.862M (+8.2%) Shares 86,777 (+2.1%) Est. Cost Unrealized
QURE UNIQURE NV 0.1%
Value $697K (-26.3%) Shares 42,635 (+7.9%) Est. Cost Unrealized
ARGX ARGENX SE 0.3%
Value $3.312M (-6.3%) Shares 4,535 (+7.9%) Est. Cost Unrealized

Exited Positions (20)

ADMA ADMA BIOLOGICS INC 2.1%
Value $23.18M Shares 1,270,894 Est. Cost Unrealized
MDT MEDTRONIC PLC 1.9%
Value $20.54M Shares 213,796 Est. Cost Unrealized
MRK MERCK & CO INC 1.8%
Value $19.77M Shares 187,834 Est. Cost Unrealized
CNC CENTENE CORP DEL 1.4%
Value $15.32M Shares 372,300 Est. Cost Unrealized
INDIVIOR PLC 1.2%
Value $12.94M Shares 360,695 Est. Cost Unrealized
UHS UNIVERSAL HLTH SVCS INC 1.1%
Value $12.52M Shares 57,409 Est. Cost Unrealized
TFX TELEFLEX INCORPORATED 1.1%
Value $12.5M Shares 102,395 Est. Cost Unrealized
ISRG INTUITIVE SURGICAL INC 0.8%
Value $8.728M Shares 15,410 Est. Cost Unrealized
GILD GILEAD SCIENCES INC 0.8%
Value $8.717M Shares 71,018 Est. Cost Unrealized
CVS CVS HEALTH CORP 0.8%
Value $8.552M Shares 107,767 Est. Cost Unrealized
SNY SANOFI SA 0.8%
Value $8.549M Shares 176,413 Est. Cost Unrealized
IQV IQVIA HLDGS INC 0.8%
Value $8.532M Shares 37,852 Est. Cost Unrealized
VEEV VEEVA SYS INC 0.7%
Value $7.253M Shares 32,489 Est. Cost Unrealized
ALGN ALIGN TECHNOLOGY INC 0.6%
Value $6.606M Shares 42,304 Est. Cost Unrealized
ELAN ELANCO ANIMAL HEALTH INC 0.4%
Value $4.691M Shares 207,311 Est. Cost Unrealized
MOH MOLINA HEALTHCARE INC 0.4%
Value $3.957M Shares 22,802 Est. Cost Unrealized
FTRE FORTREA HLDGS INC 0.3%
Value $2.854M Shares 165,439 Est. Cost Unrealized
IRON DISC MEDICINE INC 0.1%
Value $874K Shares 11,002 Est. Cost Unrealized
NPCE NEUROPACE INC 0.0%
Value $175K Shares 11,329 Est. Cost Unrealized
TMCI TREACE MED CONCEPTS INC 0.0%
Value $123K Shares 50,000 Est. Cost Unrealized

Decreased Positions (19)

CNC CENTENE CORP DEL 0.8%
Value $8.627M (-71.1%) Shares 263,486 (-63.7%) Est. Cost Unrealized
TMO THERMO FISHER SCIENTIFIC INC 0.7%
Value $7.29M (-66.8%) Shares 14,832 (-60.9%) Est. Cost Unrealized
ICLR ICON PLC 0.6%
Value $6.363M (-69.7%) Shares 57,500 (-50.1%) Est. Cost Unrealized
LLY ELI LILLY & CO 5.5%
Value $60.49M (-17.6%) Shares 65,762 (-3.7%) Est. Cost Unrealized
SYK STRYKER CORPORATION 0.7%
Value $7.215M (-59.6%) Shares 21,957 (-56.8%) Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 2.2%
Value $23.6M (-28.5%) Shares 39,805 (-41.2%) Est. Cost Unrealized
AMRX AMNEAL PHARMACEUTICALS INC 1.1%
Value $11.56M (-37.4%) Shares 930,096 (-36.5%) Est. Cost Unrealized
CNTA CENTESSA PHARMACEUTICALS PLC 1.9%
Value $20.98M (+41.8%) Shares 528,224 (-10.7%) Est. Cost Unrealized
CAH CARDINAL HEALTH INC 0.6%
Value $6.749M (-47.3%) Shares 31,941 (-48.8%) Est. Cost Unrealized
DXCM DEXCOM INC 0.9%
Value $9.403M (-37.7%) Shares 149,734 (-34.1%) Est. Cost Unrealized
WAT WATERS CORP 1.1%
Value $11.84M (-27.8%) Shares 39,763 (-8.0%) Est. Cost Unrealized
BBIO BRIDGEBIO PHARMA INC 1.7%
Value $19.14M (-18.4%) Shares 257,747 (-15.9%) Est. Cost Unrealized
ASND ASCENDIS PHARMA A/S 3.2%
Value $34.77M (-8.2%) Shares 152,034 (-14.4%) Est. Cost Unrealized
RVMD REVOLUTION MEDICINES INC 1.2%
Value $13.69M (+13.5%) Shares 140,770 (-7.1%) Est. Cost Unrealized
ABVX ABIVAX SA 0.3%
Value $2.969M (-30.9%) Shares 26,664 (-16.4%) Est. Cost Unrealized
PEN PENUMBRA INC 4.2%
Value $45.9M (+1.7%) Shares 139,779 (-3.7%) Est. Cost Unrealized
MBX MBX BIOSCIENCES INC 0.2%
Value $2.146M (-14.2%) Shares 71,894 (-9.4%) Est. Cost Unrealized
HCA HCA HEALTHCARE INC 0.6%
Value $6.318M (-2.4%) Shares 13,351 (-3.7%) Est. Cost Unrealized
RZLT REZOLUTE INC 0.0%
Value $393K (-19.3%) Shares 128,726 (-37.6%) Est. Cost Unrealized