PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q2 2026 (← Previous)

Filing Date: Aug 14, 2026

Total Value: $1.165B (100.0% shares, 0.0% debt)

Holdings (98)

New Positions (35)

ASND ASCENDIS PHARMA A/S 5.3%
Value $62.19M Shares 233,171 Est. Cost Unrealized
HUM HUMANA INC 3.2%
Value $37.49M Shares 94,375 Est. Cost Unrealized
MTD METTLER TOLEDO INTERNATIONAL 1.5%
Value $17.05M Shares 13,344 Est. Cost Unrealized
MRK MERCK & CO INC 1.4%
Value $16.33M Shares 127,118 Est. Cost Unrealized
CYTK CYTOKINETICS INC 1.4%
Value $16.33M Shares 191,686 Est. Cost Unrealized
LNTH LANTHEUS HLDGS INC 1.4%
Value $16.24M Shares 146,403 Est. Cost Unrealized
CVS CVS HEALTH CORP 1.2%
Value $14.22M Shares 137,457 Est. Cost Unrealized
GILD GILEAD SCIENCES INC 1.0%
Value $11.48M Shares 90,858 Est. Cost Unrealized
TFX TELEFLEX INCORPORATED 0.9%
Value $10.1M Shares 79,708 Est. Cost Unrealized
COR CENCORA INC 0.7%
Value $7.952M Shares 28,100 Est. Cost Unrealized
IRTC IRHYTHM HOLDINGS INC 0.7%
Value $7.755M Shares 65,196 Est. Cost Unrealized
WST WEST PHARMACEUTICAL SVSC INC 0.6%
Value $7.443M Shares 20,733 Est. Cost Unrealized
TAK TAKEDA PHARMACEUTICAL CO LTD 0.6%
Value $7.12M Shares 444,173 Est. Cost Unrealized
HNGE HINGE HEALTH INC 0.6%
Value $6.877M Shares 82,860 Est. Cost Unrealized
ARQT ARCUTIS BIOTHERAPEUTICS INC 0.5%
Value $6.347M Shares 242,069 Est. Cost Unrealized
IART INTEGRA LIFESCIENCES HLDGS C 0.5%
Value $6.263M Shares 348,746 Est. Cost Unrealized
MGTX MEIRAGTX HLDGS PLC 0.5%
Value $6.151M Shares 455,286 Est. Cost Unrealized
OCS OCULIS HOLDING AG 0.5%
Value $6.048M Shares 436,042 Est. Cost Unrealized
CNC CENTENE CORP DEL 0.5%
Value $5.662M Shares 88,200 Est. Cost Unrealized
GH GUARDANT HEALTH INC 0.5%
Value $5.506M Shares 36,701 Est. Cost Unrealized
CELC CELCUITY INC 0.5%
Value $5.456M Shares 52,155 Est. Cost Unrealized
RCUS ARCUS BIOSCIENCES INC 0.4%
Value $4.69M Shares 152,129 Est. Cost Unrealized
CRL CHARLES RIV LABS INTL INC 0.4%
Value $4.252M Shares 18,747 Est. Cost Unrealized
ELAN ELANCO ANIMAL HEALTH INC 0.4%
Value $4.245M Shares 172,489 Est. Cost Unrealized
BIO BIO RAD LABS INC 0.4%
Value $4.109M Shares 13,995 Est. Cost Unrealized
SYRE SPYRE THERAPEUTICS INC 0.4%
Value $4.103M Shares 46,217 Est. Cost Unrealized
MIRM MIRUM PHARMACEUTICALS INC 0.3%
Value $3.692M Shares 31,536 Est. Cost Unrealized
DNLI DENALI THERAPEUTICS INC 0.2%
Value $2.597M Shares 100,966 Est. Cost Unrealized
OMDA OMADA HEALTH INC 0.2%
Value $2.512M Shares 114,442 Est. Cost Unrealized
ERAS ERASCA INC 0.2%
Value $2.456M Shares 134,088 Est. Cost Unrealized
COR CENCORA INC 0.2%
Value $2.09M Shares 7,385 Est. Cost Unrealized
BCRX BIOCRYST PHARMACEUTICALS INC 0.2%
Value $2.074M Shares 207,357 Est. Cost Unrealized
OMCL OMNICELL COM 0.2%
Value $2.036M Shares 49,040 Est. Cost Unrealized
CVRX CVRX INC 0.2%
Value $1.9M Shares 369,572 Est. Cost Unrealized
HIMS HIMS & HERS HEALTH INC 0.1%
Value $1.715M Shares 49,454 Est. Cost Unrealized

Increased Positions (21)

UNH UNITEDHEALTH GROUP INC 3.1%
Value $36.69M (+133.6%) Shares 88,276 (+52.1%) Est. Cost Unrealized
ICLR ICON PUB LTD CO 2.0%
Value $23.71M (+272.6%) Shares 136,482 (+137.4%) Est. Cost Unrealized
RVMD REVOLUTION MEDICINES INC 2.3%
Value $26.82M (+95.9%) Shares 143,222 (+1.7%) Est. Cost Unrealized
SYK STRYKER CORPORATION 1.5%
Value $17.83M (+147.2%) Shares 56,637 (+157.9%) Est. Cost Unrealized
WAT WATERS CORP 1.9%
Value $22.44M (+89.5%) Shares 59,825 (+50.5%) Est. Cost Unrealized
OSCR OSCAR HEALTH INC 1.3%
Value $14.8M (+158.2%) Shares 519,016 (+3.8%) Est. Cost Unrealized
DFTX DEFINIUM THERAPEUTICS INC 1.0%
Value $11.71M (+201.9%) Shares 249,020 (+21.3%) Est. Cost Unrealized
TMO THERMO FISHER SCIENTIFIC INC 1.2%
Value $14.29M (+96.0%) Shares 28,496 (+92.1%) Est. Cost Unrealized
ARWR ARROWHEAD PHARMACEUTICALS IN 0.9%
Value $10.73M (+166.3%) Shares 131,667 (+104.8%) Est. Cost Unrealized
NVO NOVO-NORDISK A S 1.1%
Value $12.7M (+75.3%) Shares 265,016 (+34.4%) Est. Cost Unrealized
EPRX EUPRAXIA PHARMACEUTICALS INC 0.7%
Value $8.002M (+104.4%) Shares 1,210,661 (+123.8%) Est. Cost Unrealized
ROIV ROIVANT SCIENCES LTD 0.8%
Value $9.485M (+65.1%) Shares 268,008 (+29.2%) Est. Cost Unrealized
COO COOPER COS INC 1.4%
Value $15.84M (+30.4%) Shares 220,890 (+30.1%) Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 2.3%
Value $27.09M (+14.8%) Shares 49,991 (+25.6%) Est. Cost Unrealized
KOD KODIAK SCIENCES INC 0.6%
Value $7.532M (+72.2%) Shares 193,315 (+68.5%) Est. Cost Unrealized
ABVX ABIVAX SA 0.5%
Value $5.765M (+94.2%) Shares 43,264 (+62.3%) Est. Cost Unrealized
ILMN ILLUMINA INC 0.5%
Value $6.161M (+73.1%) Shares 35,040 (+21.4%) Est. Cost Unrealized
VERA VERA THERAPEUTICS INC 0.8%
Value $9.624M (+36.8%) Shares 224,289 (+28.3%) Est. Cost Unrealized
MMSI MERIT MED SYS INC 1.2%
Value $13.66M (+22.0%) Shares 197,038 (+21.3%) Est. Cost Unrealized
CLDX CELLDEX THERAPEUTICS INC NEW 1.1%
Value $12.75M (+23.7%) Shares 342,751 (+5.5%) Est. Cost Unrealized
PRAX PRAXIS PRECISION MEDICINES I 1.1%
Value $12.91M (+13.1%) Shares 38,575 (+8.9%) Est. Cost Unrealized

Exited Positions (20)

XBI SPDR SERIES TRUST 5.0%
Value $58.16M Shares 455,300 Est. Cost Unrealized
XLV SELECT SECTOR SPDR TR 3.0%
Value $35.03M Shares 238,900 Est. Cost Unrealized
ASND ASCENDIS PHARMA A/S 3.0%
Value $34.77M Shares 152,034 Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 2.3%
Value $27.22M Shares 45,900 Est. Cost Unrealized
GKOS GLAUKOS CORP 2.0%
Value $23.22M Shares 215,685 Est. Cost Unrealized
CNTA CENTESSA PHARMACEUTICALS PLC 1.8%
Value $20.98M Shares 528,224 Est. Cost Unrealized
UTHR UNITED THERAPEUTICS CORP DEL 1.6%
Value $18.8M Shares 31,700 Est. Cost Unrealized
ASCENDIS PHARMA A/S 1.5%
Value $16.92M Shares 11,505,000 Est. Cost Unrealized
NEO NEOGENOMICS INC 1.1%
Value $13.24M Shares 1,784,552 Est. Cost Unrealized
DXCM DEXCOM INC 0.8%
Value $9.403M Shares 149,734 Est. Cost Unrealized
TERN TERNS PHARMACEUTICALS INC 0.8%
Value $9.119M Shares 172,962 Est. Cost Unrealized
SLNO SOLENO THERAPEUTICS INC 0.7%
Value $8.309M Shares 248,180 Est. Cost Unrealized
BLLN BILLIONTOONE INC 0.6%
Value $6.952M Shares 88,069 Est. Cost Unrealized
CAH CARDINAL HEALTH INC 0.6%
Value $6.749M Shares 31,941 Est. Cost Unrealized
ALHC ALIGNMENT HEALTHCARE INC 0.5%
Value $6.34M Shares 359,826 Est. Cost Unrealized
PSNL PERSONALIS INC 0.5%
Value $5.543M Shares 870,097 Est. Cost Unrealized
ASND ASCENDIS PHARMA A/S 0.4%
Value $5.124M Shares 22,400 Est. Cost Unrealized
MDLN MEDLINE INC 0.3%
Value $3.862M Shares 86,777 Est. Cost Unrealized
HCA HCA HEALTHCARE INC 0.2%
Value $2.177M Shares 4,600 Est. Cost Unrealized
GMED GLOBUS MED INC 0.1%
Value $1.458M Shares 16,923 Est. Cost Unrealized

Decreased Positions (41)

THC TENET HEALTHCARE CORP 2.0%
Value $23.68M (-68.5%) Shares 126,572 (-68.2%) Est. Cost Unrealized
PEN PENUMBRA INC 1.6%
Value $19.01M (-58.6%) Shares 60,221 (-56.9%) Est. Cost Unrealized
LLY ELI LILLY & CO 4.0%
Value $47.09M (-22.2%) Shares 39,258 (-40.3%) Est. Cost Unrealized
AXSM AXSOME THERAPEUTICS INC. 4.6%
Value $53.75M (+20.3%) Shares 219,596 (-16.9%) Est. Cost Unrealized
NBIX NEUROCRINE BIOSCIENCES INC 3.1%
Value $35.97M (+26.6%) Shares 213,407 (-1.1%) Est. Cost Unrealized
CNC CENTENE CORP DEL 1.4%
Value $15.97M (+85.2%) Shares 248,867 (-5.5%) Est. Cost Unrealized
ABT ABBOTT LABORATORIES 0.6%
Value $7.462M (-48.2%) Shares 82,230 (-41.4%) Est. Cost Unrealized
ORKA ORUKA THERAPEUTICS INC 1.3%
Value $15.12M (+77.1%) Shares 158,825 (-8.7%) Est. Cost Unrealized
NTRA NATERA INC 0.5%
Value $5.993M (-50.1%) Shares 22,077 (-63.2%) Est. Cost Unrealized
JAZZ JAZZ PHARMACEUTICALS PLC 3.3%
Value $38.74M (+15.0%) Shares 160,768 (-9.8%) Est. Cost Unrealized
BLTE BELITE BIO INC 0.5%
Value $5.359M (-43.4%) Shares 34,803 (-41.4%) Est. Cost Unrealized
CMPS COMPASS PATHWAYS PLC 0.3%
Value $3.503M (-53.7%) Shares 247,589 (-81.9%) Est. Cost Unrealized
AMRX AMNEAL PHARMACEUTICALS INC 0.7%
Value $8.321M (-28.0%) Shares 480,715 (-48.3%) Est. Cost Unrealized
SNDX SYNDAX PHARMACEUTICALS INC 0.2%
Value $2.589M (-54.8%) Shares 118,422 (-51.7%) Est. Cost Unrealized
HCA HCA HEALTHCARE INC 0.3%
Value $3.234M (-48.8%) Shares 8,295 (-37.9%) Est. Cost Unrealized
TARS TARSUS PHARMACEUTICALS INC 0.2%
Value $2.554M (-54.6%) Shares 40,579 (-49.4%) Est. Cost Unrealized
DNTH DIANTHUS THERAPEUTICS INC 1.0%
Value $11.82M (-18.2%) Shares 121,222 (-29.6%) Est. Cost Unrealized
EW EDWARDS LIFESCIENCES CORP 1.9%
Value $22.66M (+11.2%) Shares 250,453 (-1.6%) Est. Cost Unrealized
MLYS MINERALYS THERAPEUTICS INC 0.1%
Value $1.684M (-56.4%) Shares 62,418 (-56.3%) Est. Cost Unrealized
MDGL MADRIGAL PHARMACEUTICALS INC 1.4%
Value $15.74M (-11.9%) Shares 29,313 (-14.2%) Est. Cost Unrealized
CGON CG ONCOLOGY INC 0.8%
Value $9.115M (-18.8%) Shares 128,286 (-22.7%) Est. Cost Unrealized
BTSG BRIGHTSPRING HEALTH SVCS INC 0.8%
Value $9.897M (+24.0%) Shares 141,914 (-24.2%) Est. Cost Unrealized
ACHC ACADIA HEALTHCARE COMPANY IN 1.3%
Value $15.5M (+13.7%) Shares 524,934 (-9.9%) Est. Cost Unrealized
MBX MBX BIOSCIENCES INC 0.3%
Value $3.918M (+82.6%) Shares 70,971 (-1.3%) Est. Cost Unrealized
TNGX TANGO THERAPEUTICS INC 0.9%
Value $10.19M (+19.9%) Shares 326,047 (-19.7%) Est. Cost Unrealized
VKTX VIKING THERAPEUTICS INC 0.9%
Value $9.96M (+16.3%) Shares 255,330 (-3.0%) Est. Cost Unrealized
CRBU CARIBOU BIOSCIENCES INC 0.1%
Value $624K (-65.7%) Shares 354,687 (-63.0%) Est. Cost Unrealized
GPCR STRUCTURE THERAPEUTICS INC 0.4%
Value $4.913M (-19.3%) Shares 91,550 (-27.6%) Est. Cost Unrealized
INDV INDIVIOR PHARMACEUTICALS INC 1.4%
Value $16.46M (-6.0%) Shares 401,208 (-30.2%) Est. Cost Unrealized
ARGX ARGENX SE 0.4%
Value $4.158M (+25.6%) Shares 4,482 (-1.2%) Est. Cost Unrealized
CAPR CAPRICOR THERAPEUTICS INC 0.3%
Value $2.943M (-21.8%) Shares 122,221 (-1.3%) Est. Cost Unrealized
RYTM RHYTHM PHARMACEUTICALS INC 1.0%
Value $11.28M (-5.1%) Shares 101,550 (-25.7%) Est. Cost Unrealized
AMLX AMYLYX PHARMACEUTICALS INC 0.2%
Value $2.581M (+27.8%) Shares 143,700 (-1.1%) Est. Cost Unrealized
QURE UNIQURE NV 0.1%
Value $1.216M (+74.4%) Shares 26,396 (-38.1%) Est. Cost Unrealized
CGEM CULLINAN THERAPEUTICS INC 0.3%
Value $3.504M (+8.4%) Shares 192,442 (-15.4%) Est. Cost Unrealized
BBIO BRIDGEBIO PHARMA INC 1.6%
Value $18.87M (-1.4%) Shares 253,358 (-1.7%) Est. Cost Unrealized
RZLT REZOLUTE INC 0.1%
Value $662K (+68.6%) Shares 127,289 (-1.1%) Est. Cost Unrealized
OM OUTSET MED INC 0.2%
Value $2.515M (+10.1%) Shares 582,122 (-2.1%) Est. Cost Unrealized
TECX TECTONIC THERAPEUTIC INC 0.1%
Value $1.569M (+10.0%) Shares 45,631 (-1.1%) Est. Cost Unrealized
HSIC SCHEIN HENRY INC 1.0%
Value $11.23M (-0.5%) Shares 134,423 (-12.2%) Est. Cost Unrealized
ITGR INTEGER HLDGS CORP 1.0%
Value $11.84M (-0.4%) Shares 126,669 (-6.2%) Est. Cost Unrealized

Unchanged Positions (1)