Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q3 2022 (← Previous) (Next →)
Filing Date: Nov 14, 2022
Total Value: $4.338B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,683,362 | $337M | 7.8% | $95.85 | +99.0% | COM | 02043Q107 |
| PTCT | PTC THERAPEUTICS INC | 5,620,580 | $282M | 6.5% | $36.25 | +35.1% | COM | 69366J200 |
| RCKT | ROCKET PHARMACEUTICALS INC | 15,802,802 | $252M | 5.8% | $17.68 | -11.7% | COM | 77313F106 |
| TMO | THERMO FISHER SCIENTIFIC INC | 435,500 | $221M | 5.1% | $545.57 | +1.6% | COM | 883556102 |
| IMCR | IMMUNOCORE HLDGS PLC | 4,451,483 | $209M | 4.8% | $38.10 | — | ADS | 45258D105 |
| MASI | MASIMO CORP | 1,439,993 | $203M | 4.7% | $167.75 | -12.9% | COM | 574795100 |
| — | PROMETHEUS BIOSCIENCES INC | 3,189,605 | $188M | 4.3% | $17.52 | — | COM | 74349U108 |
| ARGX | ARGENX SE | 467,195 | $165M | 3.8% | $322.94 | — | SPONSORED ADR | 04016X101 |
| PEN | PENUMBRA INC | 698,371 | $132M | 3.1% | $259.17 | -38.1% | COM | 70975L107 |
| — | MIRATI THERAPEUTICS INC | 1,882,663 | $131M | 3.0% | $101.79 | — | COM | 60468T105 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,369,138 | $129M | 3.0% | $25.47 | +134.6% | COM | G31249108 |
| CYTK | CYTOKINETICS INC | 2,574,198 | $125M | 2.9% | $26.72 | +80.1% | COM NEW | 23282W605 |
| ILMN | ILLUMINA INC | 564,375 | $108M | 2.5% | $341.04 | -42.0% | COM | 452327109 |
| RLMD | RELMADA THERAPEUTICS INC | 2,644,475 | $97.9M | 2.3% | $29.80 | -7.0% | COM | 75955J402 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 2,359,996 | $97.73M | 2.3% | $68.83 | -25.3% | COM | 90400D108 |
| NTRA | NATERA INC | 2,209,283 | $96.81M | 2.2% | $42.90 | +11.0% | COM | 632307104 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 3,084,215 | $86.7M | 2.0% | $8.74 | +250.9% | COM NEW | 15117B202 |
| RNAM | AVIDITY BIOSCIENCES INC | 5,170,784 | $84.44M | 1.9% | $27.03 | -29.2% | COM | 05370A108 |
| AXSM | AXSOME THERAPEUTICS INC | 1,882,164 | $83.98M | 1.9% | $41.51 | +20.4% | COM | 05464T104 |
| — | CUTERA INC | 1,770,400 | $80.73M | 1.9% | $47.55 | — | COM | 232109108 |
| VCEL | VERICEL CORP | 3,099,904 | $71.92M | 1.7% | $12.98 | +110.3% | COM | 92346J108 |
| — | IVERIC BIO INC | 3,625,000 | $65.03M | 1.5% | $17.94 | — | COM | 46583P102 |
| — | AXONICS INC | 884,974 | $62.34M | 1.4% | $21.35 | — | COM | 05465P101 |
| — | ADICET BIO INC | 4,241,472 | $60.31M | 1.4% | $16.61 | — | COM | 007002108 |
| ACAD | ACADIA PHARMACEUTICALS INC | 3,670,938 | $60.06M | 1.4% | $18.68 | -13.3% | COM | 004225108 |
| VTYX | VENTYX BIOSCIENCES INC | 1,551,778 | $54.17M | 1.2% | $18.95 | +16.8% | COM | 92332V107 |
| PMVP | PMV PHARMACEUTICALS INC | 4,356,920 | $51.85M | 1.2% | $23.66 | -38.9% | COM | 69353Y103 |
| RGNX | REGENXBIO INC | 1,845,366 | $48.77M | 1.1% | $34.74 | -14.6% | COM | 75901B107 |
| STOK | STOKE THERAPEUTICS INC | 3,651,823 | $46.89M | 1.1% | $27.59 | -42.2% | COM | 86150R107 |
| — | CINCOR PHARMA INC | 1,389,705 | $45.61M | 1.1% | $17.54 | — | COM | 17240Y109 |
| GMED | GLOBUS MED INC | 747,685 | $44.54M | 1.0% | $57.59 | +4.6% | CL A | 379577208 |
| MIST | MILESTONE PHARMACEUTICALS IN | 4,315,102 | $39.66M | 0.9% | $20.06 | -62.2% | COM | 59935V107 |
| GH | GUARDANT HEALTH INC | 725,887 | $39.07M | 0.9% | $95.11 | -46.0% | COM | 40131M109 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 4,176,837 | $35.21M | 0.8% | $22.73 | -58.4% | COM | 74366E102 |
| TARS | TARSUS PHARMACEUTICALS INC | 2,023,179 | $34.64M | 0.8% | $28.48 | -44.2% | COM | 87650L103 |
| FULC | FULCRUM THERAPEUTICS INC | 3,985,910 | $32.25M | 0.7% | $12.83 | -44.2% | COM | 359616109 |
| BCYC | BICYCLE THERAPEUTICS PLC | 1,276,276 | $29.69M | 0.7% | $55.45 | — | SPONSORED ADS | 088786108 |
| — | AVADEL PHARMACEUTICALS PLC | 5,741,939 | $28.77M | 0.7% | $7.74 | — | SPONSORED ADR | 05337M104 |
| GHRS | GH RESEARCH PLC | 2,168,957 | $25.2M | 0.6% | $20.43 | -38.2% | ORDINARY SHARES | G3855L106 |
| CCCC | C4 THERAPEUTICS INC | 2,819,472 | $24.73M | 0.6% | $27.93 | -62.8% | COM STK | 12529R107 |
| TXG | 10X GENOMICS INC | 639,654 | $18.22M | 0.4% | $79.87 | -52.3% | CL A COM | 88025U109 |
| — | 2SEVENTY BIO INC | 1,229,508 | $17.89M | 0.4% | $17.06 | — | COMMON STOCK | 901384107 |
| TNDM | TANDEM DIABETES CARE INC | 322,000 | $15.41M | 0.4% | $82.98 | -33.9% | COM NEW | 875372203 |
| APYX | APYX MEDICAL CORPORATION | 3,398,279 | $15.26M | 0.4% | $7.55 | -5.1% | COM | 03837C106 |
| — | OUTSET MED INC | 909,652 | $14.49M | 0.3% | $51.37 | — | COM | 690145107 |
| CSTL | CASTLE BIOSCIENCES INC | 516,995 | $13.48M | 0.3% | $25.00 | +12.1% | COM | 14843C105 |
| DMTKQ | DERMTECH INC | 3,118,666 | $12.35M | 0.3% | $9.75 | — | COM | 24984K105 |
| — | JOUNCE THERAPEUTICS INC | 5,106,341 | $11.95M | 0.3% | $6.72 | — | COM | 481116101 |
| — | OLINK HLDG AB | 981,918 | $11.92M | 0.3% | $27.52 | — | SPONSORED ADS | 680710100 |
| — | THIRD HARMONIC BIO INC | 609,687 | $11.57M | 0.3% | $18.97 | — | COM | 88427A107 |
| — | OYSTER PT PHARMA INC | 2,044,312 | $11.49M | 0.3% | $30.67 | — | COM | 69242L106 |
| WHWK | AADI BIOSCIENCE INC | 764,701 | $10.8M | 0.2% | $30.48 | -56.9% | COM | 00032Q104 |
| — | ALLAKOS INC | 1,643,500 | $10.06M | 0.2% | $6.12 | — | COM | 01671P100 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 1,214,572 | $9.923M | 0.2% | $20.37 | -54.9% | COM | 61225M102 |
| — | HEALTH SCIENCES ACQ CORP 2 | 1,000,000 | $9.9M | 0.2% | $9.90 | — | ORD SHS | G4411D109 |
| IMUX | IMMUNIC INC | 2,761,968 | $8.728M | 0.2% | $12.47 | -66.4% | COM | 4525EP101 |
| LUNG | PULMONX CORP | 460,847 | $7.678M | 0.2% | $48.68 | -62.2% | COM | 745848101 |
| — | RENOVACOR INC | 3,000,803 | $7.562M | 0.2% | $8.10 | — | COM | 75989E106 |
| URGN | UROGEN PHARMA LTD | 857,464 | $7.134M | 0.2% | $15.85 | -47.8% | COM | M96088105 |
| TNYA | TENAYA THERAPEUTICS INC | 2,458,750 | $7.13M | 0.2% | $21.49 | -78.3% | COM | 87990A106 |
| — | SCIENCE 37 HOLDINGS INC | 4,328,387 | $6.969M | 0.2% | $11.76 | — | COM | 808644108 |
| — | RESEARCH ALLIANCE CORP II | 637,000 | $6.262M | 0.1% | $10.25 | — | COM CL A | 760873109 |
| — | BCLS ACQUISITION CORP | 612,500 | $6.137M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| BWAY | BRAINSWAY LTD | 1,602,381 | $5.785M | 0.1% | $9.54 | — | SPONSORED ADS | 10501L106 |
| — | AKOYA BIOSCIENCES INC | 483,815 | $5.685M | 0.1% | $13.32 | — | COM | 00974H104 |
| MASS | 908 DEVICES INC | 312,000 | $5.132M | 0.1% | $20.05 | -3.1% | COM | 65443P102 |
| — | ARYA SCIENCES ACQU CORP IV | 500,000 | $4.955M | 0.1% | $10.47 | — | CL A | G31659108 |
| — | SUMMIT HEALTHCRE ACQUISTN CO | 500,000 | $4.925M | 0.1% | $10.01 | — | UNIT 06/03/2026 | G8566R128 |
| — | ARYA SCIENCES ACQUISITN CORP | 500,000 | $4.9M | 0.1% | $9.88 | — | CLASS A ORD SHS | G31658100 |
| SGHT | SIGHT SCIENCES INC | 665,323 | $4.225M | 0.1% | $32.87 | -74.3% | COM | 82657M105 |
| — | 5 01 ACQUISITION CORP | 392,000 | $3.92M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 500,000 | $3.88M | 0.1% | $6.29 | +12.0% | CLASS A ORD | 61559X104 |
| IMTX | IMMATICS N.V | 350,000 | $3.5M | 0.1% | $10.53 | +2.4% | SHS | N44445109 |
| TELA | TELA BIO INC | 390,364 | $3.326M | 0.1% | $12.40 | -33.1% | COM | 872381108 |
| — | MEDICUS SCIENCES ACQUISITION | 300,000 | $2.97M | 0.1% | $9.65 | — | CL A SHS | G5960S108 |
| JNJ | JOHNSON & JOHNSON | 18,127 | $2.961M | 0.1% | $119.09 | +28.4% | COM | 478160104 |
| XGN | EXAGEN INC | 1,048,662 | $2.842M | 0.1% | $15.73 | -64.5% | COM | 30068X103 |
| ROIV | ROIVANT SCIENCES LTD | 802,717 | $2.585M | 0.1% | $8.32 | -53.5% | SHS | G76279101 |
| — | LANDOS BIOPHARMA INC | 3,975,722 | $2.584M | 0.1% | $8.96 | — | COM | 515069102 |
| — | ESSA PHARMA INC | 1,311,294 | $2.387M | 0.1% | $28.61 | — | COM NEW | 29668H708 |
| NYXH | NYXOAH S A | 344,911 | $2.173M | 0.1% | $31.50 | -72.7% | SHS | B6S7WD106 |
| — | ASLAN PHARMACEUTICALS LTD | 3,015,987 | $1.806M | 0.0% | $3.35 | — | ADS | 04522R101 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 600,000 | $1.272M | 0.0% | $10.83 | -76.8% | COM | 63909J108 |
| — | MIROMATRIX MED INC | 280,000 | $1.226M | 0.0% | $11.65 | — | COM | 60471P108 |
| — | RENOVACOR INC | 350,000 | $28,000 | 0.0% | $0.64 | — | *W EXP 99/99/999 | 75989E114 |
| — | MEDICUS SCIENCES ACQUISITION | 33,331 | $1,000 | 0.0% | $1.02 | — | *W EXP 02/12/202 | G5960S124 |