Location: Dallas, TX
CIK: 0001791827 · Show all filings
Period: Q4 2022 (← Previous) (Next →)
Filing Date: Feb 14, 2023
Total Value: $4.616B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| XBI | SPDR SER TR | 4,062,000 | $337M | 7.3% | $77.93 | — | Call | 78464A870 |
| ARGX | ARGENX SE | 625,000 | $237M | 5.1% | $363.49 | — | SPONSORED ADR | 04016X101 |
| UTHR | UNITED THERAPEUTICS CORP DEL | 785,500 | $218M | 4.7% | $200.71 | +25.8% | COM | 91307C102 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,780,000 | $213M | 4.6% | $96.63 | +21.2% | COM | 64125C109 |
| — | AKERO THERAPEUTICS INC | 3,825,000 | $210M | 4.5% | $37.86 | — | COM | 00973Y108 |
| PRTA | PROTHENA CORP PLC | 2,953,000 | $178M | 3.9% | $40.61 | +44.2% | SHS | G72800108 |
| ARVN | ARVINAS INC | 4,950,000 | $169M | 3.7% | $51.25 | -17.9% | COM | 04335A105 |
| BSX | BOSTON SCIENTIFIC CORP | 3,256,700 | $151M | 3.3% | $42.25 | +2.5% | COM | 101137107 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 5,861,000 | $149M | 3.2% | $18.43 | +26.6% | COM | 87164F105 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 2,990,000 | $139M | 3.0% | $59.10 | -33.4% | COM | 90400D108 |
| SRPT | SAREPTA THERAPEUTICS INC | 1,055,000 | $137M | 3.0% | $102.32 | +13.3% | COM | 803607100 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 430,000 | $125M | 2.7% | $97.80 | 0.0% | COM | 558868105 |
| UHS | UNIVERSAL HLTH SVCS INC | 825,600 | $116M | 2.5% | $116.28 | 0.0% | CL B | 913903100 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 727,541 | $116M | 2.5% | $149.12 | -1.7% | SHS USD | G50871105 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 5,150,000 | $104M | 2.2% | $40.26 | -46.6% | COM | 98943L107 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 1,165,000 | $95.9M | 2.1% | $72.35 | +13.9% | COM | 00404A109 |
| SGRY | SURGERY PARTNERS INC | 3,112,000 | $86.7M | 1.9% | $26.95 | -1.7% | COM | 86881A100 |
| DXCM | DEXCOM INC | 756,800 | $85.7M | 1.9% | $94.28 | +16.4% | COM | 252131107 |
| AZN | ASTRAZENECA PLC | 1,200,000 | $81.36M | 1.8% | $64.50 | — | SPONSORED ADR | 046353108 |
| LLY | LILLY ELI & CO | 217,000 | $79.39M | 1.7% | $297.68 | +16.2% | COM | 532457108 |
| PCVX | VAXCYTE INC | 1,615,400 | $77.46M | 1.7% | $33.84 | +16.0% | COM | 92243G108 |
| RNAM | AVIDITY BIOSCIENCES INC | 3,275,000 | $72.67M | 1.6% | $19.62 | -24.0% | COM | 05370A108 |
| NTRA | NATERA INC | 1,798,900 | $72.26M | 1.6% | $69.69 | -40.9% | COM | 632307104 |
| IDYA | IDEAYA BIOSCIENCES INC | 3,824,800 | $69.5M | 1.5% | $17.94 | -6.2% | COM | 45166A102 |
| IMCR | IMMUNOCORE HLDGS PLC | 1,154,000 | $65.86M | 1.4% | $41.38 | — | ADS | 45258D105 |
| ALT | ALTIMMUNE INC | 3,990,000 | $65.64M | 1.4% | $11.39 | -1.3% | COM NEW | 02155H200 |
| RVMD | REVOLUTION MEDICINES INC | 2,475,000 | $58.95M | 1.3% | $20.59 | +3.3% | COM | 76155X100 |
| — | KARUNA THERAPEUTICS INC | 299,000 | $58.75M | 1.3% | $178.30 | — | COM | 48576A100 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 1,375,000 | $55.77M | 1.2% | $54.04 | -38.7% | COM | 04280A100 |
| AXSM | AXSOME THERAPEUTICS INC | 670,000 | $51.68M | 1.1% | $49.97 | +19.6% | COM | 05464T104 |
| VRTX | VERTEX PHARMACEUTICALS INC | 172,000 | $49.67M | 1.1% | $238.59 | +27.7% | COM | 92532F100 |
| LEGN | LEGEND BIOTECH CORP | 970,000 | $48.42M | 1.0% | $49.92 | — | SPONSORED ADS | 52490G102 |
| — | KEZAR LIFE SCIENCES INC | 6,782,400 | $47.75M | 1.0% | $12.16 | — | COM | 49372L100 |
| PLRX | PLIANT THERAPEUTICS INC | 2,240,400 | $43.31M | 0.9% | $19.34 | +8.1% | COM | 729139105 |
| VTYX | VENTYX BIOSCIENCES INC | 1,285,000 | $42.14M | 0.9% | $29.62 | 0.0% | COM | 92332V107 |
| ICLR | ICON PLC | 215,000 | $41.76M | 0.9% | $198.26 | 0.0% | SHS | G4705A100 |
| DGX | QUEST DIAGNOSTICS INC | 258,000 | $40.36M | 0.9% | $135.28 | 0.0% | COM | 74834L100 |
| BIO | BIO RAD LABS INC | 92,200 | $38.77M | 0.8% | $498.57 | -19.0% | CL A | 090572207 |
| — | BELLUS HEALTH INC NEW | 4,599,998 | $37.81M | 0.8% | $4.69 | — | COM NEW | 07987C204 |
| THC | TENET HEALTHCARE CORP | 717,300 | $35M | 0.8% | $46.22 | 0.0% | COM NEW | 88033G407 |
| — | KARYOPHARM THERAPEUTICS INC | 9,633,911 | $32.76M | 0.7% | $3.40 | — | COM | 48576U106 |
| BNTX | BIONTECH SE | 215,400 | $32.36M | 0.7% | $150.22 | — | SPONSORED ADS | 09075V102 |
| — | VERVE THERAPEUTICS INC | 1,565,000 | $30.28M | 0.7% | $29.34 | — | COM | 92539P101 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,527,087 | $29.89M | 0.6% | $18.42 | 0.0% | COM | 77313F106 |
| — | INTRA-CELLULAR THERAPIES INC | 504,000 | $26.67M | 0.6% | $52.36 | — | COM | 46116X101 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 1,755,000 | $25.97M | 0.6% | $19.82 | -11.8% | COM | 03969K108 |
| — | PROMETHEUS BIOSCIENCES INC | 204,000 | $22.44M | 0.5% | $110.00 | — | COM | 74349U108 |
| NTLA | INTELLIA THERAPEUTICS INC | 638,200 | $22.27M | 0.5% | $62.55 | -24.0% | COM | 45826J105 |
| VIR | VIR BIOTECHNOLOGY INC | 850,000 | $21.51M | 0.5% | $24.51 | 0.0% | COM | 92764N102 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 1,900,000 | $21.32M | 0.5% | $23.34 | -55.8% | COM | 71722W107 |
| BHVN | BIOHAVEN LTD | 1,492,000 | $20.71M | 0.4% | $14.12 | 0.0% | COM | G1110E107 |
| CYTK | CYTOKINETICS INC | 420,700 | $19.28M | 0.4% | $47.07 | -8.8% | COM NEW | 23282W605 |
| — | DECIPHERA PHARMACEUTICALS IN | 1,126,000 | $18.46M | 0.4% | $13.15 | — | COM | 24344T101 |
| CRBU | CARIBOU BIOSCIENCES INC | 2,882,600 | $18.1M | 0.4% | $21.74 | -59.1% | COM | 142038108 |
| — | IVERIC BIO INC | 838,407 | $17.95M | 0.4% | $21.41 | — | COM | 46583P102 |
| — | POINT BIOPHARMA GLOBAL INC | 2,432,400 | $17.73M | 0.4% | $7.73 | — | COM | 730541109 |
| — | NANOSTRING TECHNOLOGIES INC | 2,057,200 | $16.4M | 0.4% | $9.60 | — | COM | 63009R109 |
| TWST | TWIST BIOSCIENCE CORP | 611,000 | $14.55M | 0.3% | $29.00 | 0.0% | COM | 90184D100 |
| BCAB | BIOATLA INC | 1,260,000 | $10.39M | 0.2% | $8.30 | 0.0% | COM | 09077B104 |
| CMPX | COMPASS THERAPEUTICS INC | 2,000,000 | $10.06M | 0.2% | $3.29 | +21.3% | COM | 20454B104 |
| SGMO | SANGAMO THERAPEUTICS INC | 2,748,300 | $8.63M | 0.2% | $4.96 | -21.8% | COM | 800677106 |
| — | ALPINE IMMUNE SCIENCES INC | 1,028,200 | $7.557M | 0.2% | $10.23 | — | COM | 02083G100 |
| — | KINNATE BIOPHARMA INC | 1,212,700 | $7.397M | 0.2% | $11.95 | — | COM | 49705R105 |
| ANTX | AN2 THERAPEUTICS INC | 743,600 | $7.087M | 0.2% | $14.92 | -10.2% | COM | 037326105 |
| IPSC | CENTURY THERAPEUTICS INC | 1,303,600 | $6.687M | 0.1% | $19.69 | -52.1% | COM | 15673T100 |
| — | MEDICUS SCIENCES ACQUISITION | 520,000 | $5.236M | 0.1% | $9.65 | — | CL A SHS | G5960S108 |
| — | GRAPHITE BIO INC | 1,575,000 | $5.229M | 0.1% | $15.48 | — | COM | 38870X104 |
| — | ARYA SCIENCES ACQU CORP IV | 500,000 | $5.05M | 0.1% | $10.47 | — | CL A | G31659108 |
| — | PANACEA ACQUISITION CORP II | 500,000 | $5.025M | 0.1% | $10.02 | — | CL A SHS | G6882C106 |
| — | ESSA PHARMA INC | 1,855,400 | $4.676M | 0.1% | $9.93 | — | COM NEW | 29668H708 |
| — | HEALTH SCIENCES ACQ CORP 2 | 400,000 | $3.992M | 0.1% | $11.00 | — | ORD SHS | G4411D109 |
| SYRS | SYROS PHARMACEUTICALS INC | 900,000 | $3.231M | 0.1% | $8.12 | -46.6% | COM NEW | 87184Q206 |
| — | CYTEIR THERAPEUTICS INC | 1,795,800 | $2.963M | 0.1% | $20.50 | — | COM | 23284P103 |
| — | CAREMAX INC | 755,329 | $2.757M | 0.1% | $12.86 | — | COM CL A | 14171W103 |
| — | SOCIAL CAP SUVRETTA HLDS CRP | 200,000 | $2.012M | 0.0% | $10.12 | — | CLASS A ORD SHS | G8253U103 |
| — | SOCIAL CAP SUVRETTA HLDS CP | 200,000 | $2.01M | 0.0% | $10.10 | — | CLASS A ORD SHS | G8253Y105 |
| SCYX | SCYNEXIS INC | 1,140,600 | $1.779M | 0.0% | $4.41 | -49.9% | COM NEW | 811292200 |
| HYPR | HYPERFINE INC | 1,503,754 | $1.263M | 0.0% | $9.78 | -90.7% | COM CL A | 44916K106 |
| FATE | FATE THERAPEUTICS INC | 104,653 | $1.056M | 0.0% | $18.78 | 0.0% | COM | 31189P102 |
| ZLAB | ZAI LAB LTD | 31,309 | $961K | 0.0% | $34.20 | — | ADR | 98887Q104 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 37,898 | $879K | 0.0% | $20.16 | 0.0% | COM | 19459J104 |
| ACIU | AC IMMUNE SA | 325,400 | $664K | 0.0% | $3.06 | -15.8% | SHS | H00263105 |
| — | REUNION NEUROSCIENCE INC | 560,300 | $504K | 0.0% | $1.43 | — | COM | 76134G103 |
| — | NUVATION BIO INC | 99,999 | $14,450 | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |
| — | MEDICUS SCIENCES ACQUISITION | 57,770 | $5,199 | 0.0% | $1.00 | — | *W EXP 02/12/202 | G5960S124 |