Avidity Partners Management LP Quant / Systematic

CIK: 0001791827 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 15, 2025

Total Value ($000): $524,679 (100.0% shares, 0.0% debt)

Holdings (67)

BSX BOSTON SCIENTIFIC CORP 6.5%
Value ($000) $33,896 Shares 336,000 Est. Cost $49.10 Unrealized +105.1%
DNTH DIANTHUS THERAPEUTICS INC 5.9%
Value ($000) $31,217 Shares 1,720,902 Est. Cost $18.09 Unrealized +21.9%
UNH UNITEDHEALTH GROUP INC 5.0%
Value ($000) $26,449 Shares 50,500 Est. Cost $548.30 Unrealized -8.9%
CGON CG ONCOLOGY INC 4.6%
Value ($000) $24,023 Shares 980,942 Est. Cost $39.58 Unrealized -28.9%
HUM HUMANA INC 4.1%
Value ($000) $21,433 Shares 81,000 Est. Cost $348.89 Unrealized -23.5%
HUM HUMANA INC 4.0%
Value ($000) $21,168 Shares 80,000 Est. Cost $348.89 Unrealized -23.5%
NTRA NATERA INC 3.2%
Value ($000) $16,856 Shares 119,200 Est. Cost $55.01 Unrealized +192.2%
REGN REGENERON PHARMACEUTICALS 3.1%
Value ($000) $16,109 Shares 25,400 Est. Cost $734.10 Unrealized -6.8%
EXAS EXACT SCIENCES CORP 2.9%
Value ($000) $15,281 Shares 353,000 Est. Cost $55.79 Unrealized -9.2%
BEAM BEAM THERAPEUTICS INC 2.6%
Value ($000) $13,857 Shares 709,517 Est. Cost $26.20 Unrealized 0.0%
GKOS GLAUKOS CORP 2.5%
Value ($000) $13,188 Shares 134,000 Est. Cost $101.65 Unrealized +31.2%
DXCM DEXCOM INC 2.3%
Value ($000) $12,292 Shares 180,000 Est. Cost $113.20 Unrealized -27.9%
RARE ULTRAGENYX PHARMACEUTICAL IN 2.2%
Value ($000) $11,663 Shares 322,100 Est. Cost $51.17 Unrealized -18.7%
SNDX SYNDAX PHARMACEUTICALS INC 2.2%
Value ($000) $11,364 Shares 925,000 Est. Cost $18.49 Unrealized -23.7%
COR CENCORA INC 2.1%
Value ($000) $10,929 Shares 39,300 Est. Cost $249.56 Unrealized 0.0%
JAZZ JAZZ PHARMACEUTICALS PLC 1.9%
Value ($000) $9,932 Shares 80,000 Est. Cost $142.84 Unrealized -8.7%
THC TENET HEALTHCARE CORP 1.8%
Value ($000) $9,684 Shares 72,000 Est. Cost $51.02 Unrealized +158.1%
NBIX NEUROCRINE BIOSCIENCES INC 1.8%
Value ($000) $9,478 Shares 85,700 Est. Cost $96.63 Unrealized +31.1%
DHR DANAHER CORPORATION 1.7%
Value ($000) $9,123 Shares 44,500 Est. Cost $217.74 Unrealized -0.4%
AXSM AXSOME THERAPEUTICS INC 1.7%
Value ($000) $8,981 Shares 77,000 Est. Cost $55.95 Unrealized +103.6%
GMAB GENMAB A/S 1.6%
Value ($000) $8,480 Shares 433,100 Est. Cost — Unrealized —
INSM INSMED INC 1.6%
Value ($000) $8,163 Shares 107,000 Est. Cost $48.37 Unrealized +58.2%
OGN ORGANON & CO 1.5%
Value ($000) $7,966 Shares 535,000 Est. Cost $15.11 Unrealized 0.0%
TMO THERMO FISHER SCIENTIFIC INC 1.5%
Value ($000) $7,713 Shares 15,500 Est. Cost $529.04 Unrealized +2.0%
XENE XENON PHARMACEUTICALS INC 1.5%
Value ($000) $7,683 Shares 229,000 Est. Cost $37.48 Unrealized +1.3%
XBI SPDR SER TR 1.5%
Value ($000) $7,623 Shares 94,000 Est. Cost $81.10 Unrealized —
CNTA CENTESSA PHARMACEUTICALS PLC 1.4%
Value ($000) $7,607 Shares 529,000 Est. Cost $15.99 Unrealized —
RVMD REVOLUTION MEDICINES INC 1.4%
Value ($000) $7,532 Shares 213,000 Est. Cost $30.74 Unrealized +32.0%
TEVA TEVA PHARMACEUTICAL INDS LTD 1.4%
Value ($000) $7,393 Shares 481,000 Est. Cost $15.37 Unrealized —
AVTR AVANTOR INC 1.4%
Value ($000) $7,343 Shares 453,000 Est. Cost $21.56 Unrealized -12.1%
IDYA IDEAYA BIOSCIENCES INC 1.4%
Value ($000) $7,289 Shares 445,000 Est. Cost $26.67 Unrealized -20.1%
DOCS DOXIMITY INC 1.4%
Value ($000) $7,109 Shares 122,500 Est. Cost $63.15 Unrealized 0.0%
JANX JANUX THERAPEUTICS INC 1.3%
Value ($000) $6,966 Shares 258,000 Est. Cost $39.67 Unrealized -5.0%
HQY HEALTHEQUITY INC 1.3%
Value ($000) $6,893 Shares 78,000 Est. Cost $102.56 Unrealized 0.0%
— BLUEPRINT MEDICINES CORP 1.2%
Value ($000) $6,063 Shares 68,500 Est. Cost $57.39 Unrealized —
ARVN ARVINAS INC 1.0%
Value ($000) $5,265 Shares 750,000 Est. Cost $47.79 Unrealized -67.2%
UTHR UNITED THERAPEUTICS CORP DEL 1.0%
Value ($000) $5,179 Shares 16,800 Est. Cost $342.70 Unrealized 0.0%
PHAT PHATHOM PHARMACEUTICALS INC 1.0%
Value ($000) $5,016 Shares 800,000 Est. Cost $20.69 Unrealized -70.7%
SNDX SYNDAX PHARMACEUTICALS INC 0.9%
Value ($000) $4,912 Shares 400,000 Est. Cost $18.49 Unrealized -23.7%
IMUX IMMUNIC INC 0.9%
Value ($000) $4,855 Shares 4,454,408 Est. Cost $1.30 Unrealized -16.9%
BRKR BRUKER CORP 0.9%
Value ($000) $4,800 Shares 115,000 Est. Cost $56.42 Unrealized -8.2%
CATX PERSPECTIVE THERAPEUTICS INC 0.9%
Value ($000) $4,680 Shares 2,197,270 Est. Cost $14.32 Unrealized -79.0%
CNTX CONTEXT THERAPEUTICS INC 0.9%
Value ($000) $4,576 Shares 7,477,200 Est. Cost $1.72 Unrealized -49.5%
ORKA ORUKA THERAPEUTICS INC 0.7%
Value ($000) $3,613 Shares 352,124 Est. Cost $34.79 Unrealized -64.2%
QURE UNIQURE NV 0.7%
Value ($000) $3,564 Shares 336,200 Est. Cost $9.06 Unrealized +54.7%
BHVN BIOHAVEN LTD 0.7%
Value ($000) $3,486 Shares 145,000 Est. Cost $35.42 Unrealized -0.4%
ARVN ARVINAS INC 0.6%
Value ($000) $2,900 Shares 413,162 Est. Cost $47.79 Unrealized -67.2%
ACAD ACADIA PHARMACEUTICALS INC 0.5%
Value ($000) $2,807 Shares 169,000 Est. Cost $18.17 Unrealized 0.0%
RPRX ROYALTY PHARMA PLC 0.5%
Value ($000) $2,708 Shares 87,000 Est. Cost $31.70 Unrealized 0.0%
BBIO BRIDGEBIO PHARMA INC 0.5%
Value ($000) $2,593 Shares 75,000 Est. Cost $33.72 Unrealized 0.0%
KZR KEZAR LIFE SCIENCES INC 0.5%
Value ($000) $2,453 Shares 502,600 Est. Cost $7.45 Unrealized -18.5%
— AKERO THERAPEUTICS INC 0.4%
Value ($000) $2,307 Shares 57,000 Est. Cost $27.82 Unrealized —
SLNO SOLENO THERAPEUTICS INC 0.4%
Value ($000) $2,286 Shares 32,000 Est. Cost $48.69 Unrealized 0.0%
CAPR CAPRICOR THERAPEUTICS INC 0.4%
Value ($000) $2,268 Shares 239,000 Est. Cost $13.88 Unrealized 0.0%
LXEO LEXEO THERAPEUTICS INC 0.4%
Value ($000) $2,238 Shares 645,000 Est. Cost $4.43 Unrealized 0.0%
VERA VERA THERAPEUTICS INC 0.4%
Value ($000) $2,186 Shares 91,000 Est. Cost $44.28 Unrealized -27.4%
RGNX REGENXBIO INC 0.4%
Value ($000) $1,859 Shares 260,000 Est. Cost $17.79 Unrealized -58.2%
IONS IONIS PHARMACEUTICALS INC 0.3%
Value ($000) $1,810 Shares 60,000 Est. Cost $32.75 Unrealized 0.0%
MIRM MIRUM PHARMACEUTICALS INC 0.3%
Value ($000) $1,802 Shares 40,000 Est. Cost $27.38 Unrealized +72.1%
NAMS NEWAMSTERDAM PHARMA COMPANY 0.3%
Value ($000) $1,392 Shares 68,000 Est. Cost $19.16 Unrealized +16.0%
AGL AGILON HEALTH INC 0.3%
Value ($000) $1,321 Shares 305,100 Est. Cost $3.48 Unrealized 0.0%
SCYX SCYNEXIS INC 0.2%
Value ($000) $1,170 Shares 1,228,910 Est. Cost $2.82 Unrealized -61.7%
PCVX VAXCYTE INC 0.2%
Value ($000) $868 Shares 23,000 Est. Cost $79.95 Unrealized 0.0%
KPTI KARYOPHARM THERAPEUTICS INC 0.1%
Value ($000) $503 Shares 134,566 Est. Cost $8.54 Unrealized 0.0%
ELVN ENLIVEN THERAPEUTICS INC 0.0%
Value ($000) $222 Shares 11,300 Est. Cost $21.52 Unrealized 0.0%
HYPR HYPERFINE INC 0.0%
Value ($000) $159 Shares 222,174 Est. Cost $9.78 Unrealized -89.5%
RVPH REVIVA PHARMACEUTCLS HLDGS I 0.0%
Value ($000) $132 Shares 138,000 Est. Cost $1.57 Unrealized 0.0%