Location: Luxembourg
CIK: 0001053906 · Show all filings
Period: Q2 2022 (← Previous) (Next →)
Filing Date: Aug 11, 2022
Total Value: $1.872B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ARGX | ARGENX SE | 400,000 | $152M | 8.1% | $216.30 | — | SPONSORED ADR | 04016X101 |
| LXRX | LEXICON PHARMACEUTICALS INC | 71,178,364 | $132M | 7.1% | $6.62 | -71.2% | COM NEW | 528872302 |
| ONC | BEIGENE LTD | 650,000 | $105M | 5.6% | $156.62 | — | SPONSORED ADR | 07725L102 |
| — | WW INTL INC | 14,818,300 | $94.69M | 5.1% | $37.82 | — | COM | 98262P101 |
| — | SEAGEN INC | 525,000 | $92.89M | 5.0% | $160.93 | — | COM | 81181C104 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 600,000 | $87.51M | 4.7% | $97.14 | +46.0% | COM | 02043Q107 |
| — | MIRATI THERAPEUTICS INC | 1,100,000 | $73.84M | 3.9% | $166.44 | — | COM | 60468T105 |
| — | BELLUS HEALTH INC NEW | 7,000,000 | $64.68M | 3.5% | $5.24 | — | COM NEW | 07987C204 |
| FATE | FATE THERAPEUTICS INC | 2,600,000 | $64.43M | 3.4% | $28.23 | -2.3% | COM | 31189P102 |
| CYTK | CYTOKINETICS INC | 1,275,000 | $50.09M | 2.7% | $29.98 | +34.3% | COM NEW | 23282W605 |
| SRRK | SCHOLAR ROCK HLDG CORP | 8,750,034 | $48.04M | 2.6% | $10.79 | -33.4% | COM | 80706P103 |
| C | CITIGROUP INC | 1,000,000 | $45.99M | 2.5% | — | — | Call | 172967424 |
| FOLD | AMICUS THERAPEUTICS INC | 4,000,000 | $42.96M | 2.3% | $11.63 | -29.2% | COM | 03152W109 |
| SEER | SEER INC | 4,750,000 | $42.51M | 2.3% | $63.62 | -85.6% | COM CL A | 81578P106 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,500,000 | $39.66M | 2.1% | $16.33 | — | COM | 15678U128 |
| — | IGM BIOSCIENCES INC | 2,000,000 | $36.06M | 1.9% | $61.09 | — | COM | 449585108 |
| — | MORPHIC HLDG INC | 1,650,000 | $35.8M | 1.9% | $23.38 | — | COM | 61775R105 |
| KRYS | KRYSTAL BIOTECH INC | 500,000 | $32.83M | 1.8% | $56.38 | +10.3% | COM | 501147102 |
| — | DIREXION SHS ETF TR | 4,000,000 | $26.96M | 1.4% | — | — | Call | 25490K323 |
| FHTX | FOGHORN THERAPEUTICS INC | 1,720,720 | $23.4M | 1.2% | $19.16 | -32.6% | COM | 344174107 |
| — | SPRINGWORKS THERAPEUTICS INC | 900,000 | $22.16M | 1.2% | $53.27 | — | COM | 85205L107 |
| GOSS | GOSSAMER BIO INC | 2,358,968 | $19.75M | 1.1% | $17.62 | -56.0% | COM | 38341P102 |
| KYMR | KYMERA THERAPEUTICS INC | 1,000,000 | $19.69M | 1.1% | $51.28 | -54.4% | COM | 501575104 |
| KURA | KURA ONCOLOGY INC | 1,050,000 | $19.25M | 1.0% | $18.14 | -20.7% | COM | 50127T109 |
| — | EQRX INC | 4,000,000 | $18.76M | 1.0% | $6.82 | — | COM | 26886C107 |
| SDGR | SCHRODINGER INC | 700,000 | $18.49M | 1.0% | $37.76 | -28.8% | COM | 80810D103 |
| — | GENERATION BIO CO | 2,814,191 | $18.46M | 1.0% | $21.00 | — | COM | 37148K100 |
| ERAS | ERASCA INC | 3,172,221 | $17.67M | 0.9% | $20.63 | -68.3% | COM | 29479A108 |
| DNLI | DENALI THERAPEUTICS INC | 600,000 | $17.66M | 0.9% | $31.47 | -16.8% | COM | 24823R105 |
| REPL | REPLIMUNE GROUP INC | 900,000 | $15.73M | 0.8% | $20.83 | -21.1% | COM | 76029N106 |
| — | SAGE THERAPEUTICS INC | 450,000 | $14.54M | 0.8% | $68.21 | — | COM | 78667J108 |
| NTLA | INTELLIA THERAPEUTICS INC | 275,000 | $14.23M | 0.8% | $33.42 | +51.9% | COM | 45826J105 |
| EVO | EVOTEC AG | 1,149,425 | $13.77M | 0.7% | $23.75 | — | SPONSORED ADS | 30050E105 |
| RLAY | RELAY THERAPEUTICS INC | 700,000 | $11.72M | 0.6% | $35.08 | -38.9% | COM | 75943R102 |
| — | MERSANA THERAPEUTICS INC | 2,200,000 | $10.16M | 0.5% | $14.43 | — | COM | 59045L106 |
| AUPH | AURINIA PHARMACEUTICALS INC | 1,000,000 | $10.05M | 0.5% | $17.08 | -34.5% | COM | 05156V102 |
| — | REPARE THERAPEUTICS INC | 700,000 | $9.793M | 0.5% | $28.89 | — | COM | 760273102 |
| WVE | WAVE LIFE SCIENCES LTD | 3,000,000 | $9.75M | 0.5% | $3.30 | -41.8% | SHS | Y95308105 |
| NBP | I MAB | 850,000 | $9.605M | 0.5% | $36.36 | — | SPONSORED ADS | 44975P103 |
| — | TALARIS THERAPEUTICS INC | 2,064,262 | $9.31M | 0.5% | $14.69 | — | COM | 87410C104 |
| — | ALLOVIR INC | 2,323,371 | $9.061M | 0.5% | $27.50 | — | COM | 019818103 |
| — | OMEGA THERAPEUTICS INC | 2,273,530 | $8.639M | 0.5% | $18.85 | — | COM | 68217N105 |
| — | ITEOS THERAPEUTICS INC | 400,000 | $8.24M | 0.4% | $24.67 | — | COM | 46565G104 |
| — | ATARA BIOTHERAPEUTICS INC | 1,000,000 | $7.79M | 0.4% | $17.77 | — | COM | 046513107 |
| — | OMEGA ALPHA SPAC | 750,000 | $7.388M | 0.4% | $9.90 | — | CL A | G6749V107 |
| — | IKENA ONCOLOGY INC | 1,549,513 | $6.864M | 0.4% | $28.25 | — | COM | 45175G108 |
| — | SELECTA BIOSCIENCES INC | 4,883,200 | $6.397M | 0.3% | $3.12 | — | COM | 816212104 |
| — | VERVE THERAPEUTICS INC | 400,000 | $6.112M | 0.3% | $60.25 | — | COM | 92539P101 |
| — | Y-MABS THERAPEUTICS INC | 400,000 | $6.052M | 0.3% | $24.99 | — | COM | 984241109 |
| — | EXSCIENTIA PLC | 550,000 | $5.99M | 0.3% | $19.76 | — | ADS | 30223G102 |
| — | AGENUS INC | 3,000,000 | $5.82M | 0.3% | $3.98 | — | COM NEW | 00847G705 |
| — | AMBRX BIOPHARMA INC | 2,152,291 | $5.704M | 0.3% | $13.20 | — | SPONSORED ADS | 02290A102 |
| — | ACHILLES THERAPEUTICS PLC | 2,255,375 | $5.684M | 0.3% | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | KRONOS BIO INC | 1,542,954 | $5.616M | 0.3% | $27.50 | — | COM | 50107A104 |
| DSGN | DESIGN THERAPEUTICS INC | 400,000 | $5.6M | 0.3% | $31.14 | -56.6% | COM | 25056L103 |
| OVID | OVID THERAPEUTICS INC | 2,500,000 | $5.375M | 0.3% | $6.69 | -63.9% | COM | 690469101 |
| — | OATLY GROUP AB | 1,500,000 | $5.19M | 0.3% | $24.46 | — | SPONSORED ADS | 67421J108 |
| SQZB | SQZ BIOTECHNOLOGIES CO | 1,606,309 | $5.108M | 0.3% | $28.98 | — | COM | 78472W104 |
| — | ALPINE IMMUNE SCIENCES INC | 593,030 | $5.047M | 0.3% | $8.79 | — | COM | 02083G100 |
| — | MARINUS PHARMACEUTICALS INC | 1,000,000 | $4.84M | 0.3% | $14.99 | — | COM NEW | 56854Q200 |
| — | CONTRAFECT CORP | 1,500,000 | $4.605M | 0.2% | $4.97 | — | COM NEW | 212326300 |
| — | LEAP THERAPEUTICS INC | 4,000,000 | $4.6M | 0.2% | $2.55 | — | COM | 52187K101 |
| — | LYELL IMMUNOPHARMA INC | 700,000 | $4.564M | 0.2% | $16.24 | — | COM | 55083R104 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 1,646,517 | $4.05M | 0.2% | $30.42 | -92.4% | COM | 09203E105 |
| ALXO | ALX ONCOLOGY HLDGS INC | 500,000 | $4.045M | 0.2% | $64.13 | -83.0% | COM | 00166B105 |
| TSHA | TAYSHA GENE THERAPIES INC | 1,040,882 | $3.872M | 0.2% | $23.52 | -83.1% | COM SHS | 877619106 |
| — | SYROS PHARMACEUTICALS INC | 4,000,000 | $3.851M | 0.2% | $4.32 | — | COM | 87184Q107 |
| SE | SEA LTD | 57,500 | $3.844M | 0.2% | $119.79 | — | SPONSORED ADS | 81141R100 |
| NBTX | NANOBIOTIX | 1,000,000 | $3.8M | 0.2% | $16.50 | — | SPONSORED ADS | 63009J107 |
| PFTA | PORTAGE FINTECH ACQUISITN CO | 380,000 | $3.705M | 0.2% | $10.00 | — | CLASS A ORD SHS | G7185D106 |
| RXRX | RECURSION PHARMACEUTICALS IN | 450,000 | $3.663M | 0.2% | $19.06 | -64.9% | CL A | 75629V104 |
| RNAM | AVIDITY BIOSCIENCES INC | 250,000 | $3.633M | 0.2% | $26.70 | -44.3% | COM | 05370A108 |
| ACIU | AC IMMUNE SA | 1,000,000 | $3.61M | 0.2% | $11.29 | -69.7% | SHS | H00263105 |
| DYN | DYNE THERAPEUTICS INC | 525,000 | $3.607M | 0.2% | $20.85 | -67.0% | COM | 26818M108 |
| — | ADVERUM BIOTECHNOLOGIES INC | 3,000,000 | $3.6M | 0.2% | $9.97 | — | COM | 00773U108 |
| — | APTINYX INC | 6,116,493 | $3.412M | 0.2% | $2.87 | — | COM | 03836N103 |
| STOK | STOKE THERAPEUTICS INC | 250,000 | $3.303M | 0.2% | $24.59 | -38.2% | COM | 86150R107 |
| IVVD | ADAGIO THERAPEUTICS INC | 1,000,000 | $3.28M | 0.2% | $6.12 | -48.7% | COM | 00534A102 |
| CGEM | CULLINAN ONCOLOGY INC | 250,000 | $3.205M | 0.2% | $28.21 | -59.8% | COM | 230031106 |
| — | RUBIUS THERAPEUTICS INC | 3,701,580 | $3.149M | 0.2% | $20.48 | — | COM | 78116T103 |
| — | HOOKIPA PHARMA INC | 1,849,616 | $3.015M | 0.2% | $4.24 | — | COM | 43906K100 |
| — | PRAXIS PRECISION MEDICINES I | 1,200,000 | $2.94M | 0.2% | $41.24 | — | COM | 74006W108 |
| — | VIGIL NEUROSCIENCE INC | 1,121,191 | $2.893M | 0.2% | $7.03 | — | COM | 92673K108 |
| MIR | MIRION TECHNOLOGIES INC | 500,000 | $2.88M | 0.2% | $10.74 | -31.5% | COM CL A | 60471A101 |
| — | VOR BIOPHARMA INC | 550,000 | $2.734M | 0.1% | $43.10 | — | COM | 929033108 |
| — | CINCOR PHARMA INC | 137,010 | $2.581M | 0.1% | $18.84 | — | COM | 17240Y109 |
| SANA | SANA BIOTECHNOLOGY INC | 400,000 | $2.572M | 0.1% | $32.56 | -80.4% | COM | 799566104 |
| IMUX | IMMUNIC INC | 700,000 | $2.429M | 0.1% | $10.33 | -38.0% | COM | 4525EP101 |
| — | ZYMEWORKS INC | 450,000 | $2.385M | 0.1% | $43.78 | — | COM | 98985W102 |
| BBIO | BRIDGEBIO PHARMA INC | 250,000 | $2.27M | 0.1% | $32.20 | -74.0% | COM | 10806X102 |
| — | TCR2 THERAPEUTICS INC | 750,000 | $2.175M | 0.1% | $19.56 | — | COM | 87808K106 |
| — | INSTIL BIO INC | 450,000 | $2.079M | 0.1% | $25.08 | — | COM | 45783C101 |
| — | SENTI BIOSCIENCES INC | 1,055,555 | $2.074M | 0.1% | $1.96 | — | COM | 81726A100 |
| ADAG | ADAGENE INC | 1,000,000 | $2.066M | 0.1% | $17.07 | — | ADS | 005329107 |
| IMMP | IMMUTEP LTD | 1,000,000 | $2.03M | 0.1% | $3.87 | — | SPONSORED ADS | 45257L108 |
| — | 111 INC | 966,349 | $1.991M | 0.1% | $9.49 | — | ADS | 68247Q102 |
| — | NEXIMMUNE INC | 1,200,000 | $1.932M | 0.1% | $19.08 | — | COM | 65344D109 |
| — | GRAPHITE BIO INC | 700,000 | $1.925M | 0.1% | $30.73 | — | COM | 38870X104 |
| — | HARPOON THERAPEUTICS INC | 1,000,000 | $1.91M | 0.1% | $15.27 | — | COM | 41358P106 |
| — | FUSION PHARMACEUTICALS INC | 750,000 | $1.868M | 0.1% | $9.98 | — | COM | 36118A100 |
| — | SOLID BIOSCIENCES INC | 3,000,000 | $1.847M | 0.1% | $4.75 | — | COM | 83422E105 |
| — | GRITSTONE BIO INC | 750,000 | $1.815M | 0.1% | $12.86 | — | COM | 39868T105 |
| ORIC | ORIC PHARMACEUTICALS INC | 400,000 | $1.792M | 0.1% | $24.42 | -83.7% | COM | 68622P109 |
| MREO | MEREO BIOPHARMA GROUP PLC | 1,500,000 | $1.68M | 0.1% | $3.37 | — | ADS | 589492107 |
| CRDF | CARDIFF ONCOLOGY INC | 750,000 | $1.65M | 0.1% | $6.60 | -74.6% | COM | 14147L108 |
| — | 23ANDME HOLDING CO | 661,009 | $1.639M | 0.1% | $6.66 | — | CLASS A COM | 90138Q108 |
| — | KINNATE BIOPHARMA INC | 125,000 | $1.576M | 0.1% | $39.78 | — | COM | 49705R105 |
| — | CYCLERION THERAPEUTICS INC | 2,779,122 | $1.525M | 0.1% | $7.29 | — | COM | 23255M105 |
| — | AXCELLA HEALTH INC | 712,500 | $1.446M | 0.1% | $6.82 | — | COM | 05454B105 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 75,000 | $1.445M | 0.1% | $22.45 | -47.1% | COM | 03237H101 |
| XLO | XILIO THERAPEUTICS INC | 450,000 | $1.314M | 0.1% | $17.03 | -77.8% | COM | 98422T100 |
| — | ARAVIVE INC | 1,311,291 | $1.295M | 0.1% | $11.29 | — | COM | 03890D108 |
| — | CURIS INC | 1,300,000 | $1.28M | 0.1% | $3.14 | — | COM NEW | 231269200 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 110,532 | $1.274M | 0.1% | $13.01 | -9.5% | COM CL A | 46333X108 |
| OLMA | OLEMA PHARMACEUTICALS INC | 260,500 | $1.06M | 0.1% | $46.89 | -93.2% | COM | 68062P106 |
| — | ORCHARD THERAPEUTICS PLC | 1,803,858 | $1.054M | 0.1% | $8.41 | — | ADS | 68570P101 |
| — | IGM BIOSCIENCES INC | 50,000 | $902K | 0.0% | $61.09 | — | Call | 449585108 |
| — | MEI PHARMA INC | 1,000,000 | $605K | 0.0% | $3.78 | — | COM NEW | 55279B202 |
| — | LAVA THERAPEUTICS NV | 200,000 | $590K | 0.0% | $15.19 | — | SHS | N51517105 |
| — | CODIAK BIOSCIENCES INC | 200,000 | $576K | 0.0% | $15.08 | — | COM | 192010106 |
| CRBU | CARIBOU BIOSCIENCES INC | 105,347 | $572K | 0.0% | $24.45 | -68.7% | COM | 142038108 |
| — | HIPPO HLDGS INC | 600,000 | $527K | 0.0% | $4.68 | — | COM | 433539103 |
| CRVS | CORVUS PHARMACEUTICALS INC | 500,000 | $495K | 0.0% | $2.96 | -58.6% | COM | 221015100 |
| — | METACRINE INC | 924,898 | $462K | 0.0% | $10.21 | — | COM | 59101E103 |
| — | MINK THERAPEUTICS INC | 289,588 | $408K | 0.0% | $4.46 | — | COM | 603693102 |
| — | YUMANITY THERAPEUTICS INC | 217,391 | $396K | 0.0% | $17.00 | — | COM | 98872L102 |
| CLF | CLEVELAND-CLIFFS INC NEW | 25,000 | $384K | 0.0% | $23.90 | 0.0% | COM | 185899101 |
| — | UNITED STS NAT GAS FD LP | 20,000 | $380K | 0.0% | $19.00 | — | UNIT PAR | 912318300 |
| — | APPLIED THERAPEUTICS INC | 400,000 | $379K | 0.0% | $20.66 | — | COM | 03828A101 |
| SPRO | SPERO THERAPEUTICS INC | 500,000 | $371K | 0.0% | $11.60 | -74.9% | COM | 84833T103 |
| BBWI | BATH & BODY WORKS INC | 12,500 | $337K | 0.0% | $39.33 | 0.0% | COM | 070830104 |
| — | SIGILON THERAPEUTICS INC | 276,000 | $229K | 0.0% | $48.03 | — | COM | 82657L107 |
| — | CIDARA THERAPEUTICS INC | 224,675 | $110K | 0.0% | $3.69 | — | COM | 171757107 |
| — | ASTRIA THERAPEUTICS INC | 33,333 | $100K | 0.0% | $8.85 | — | COM | 04635X102 |
| KLDO | KALEIDO BIOSCIENCES INC | 500,500 | $31,000 | 0.0% | $13.76 | -98.5% | COM | 483347100 |