PFM Health Sciences, LP Quant / Systematic

Location: San Francisco, CA

CIK: 0001442756 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value: $2.264B (96.0% shares, 4.0% debt)

Holdings (78)

— HORIZON THERAPEUTICS PUB L 5.3%
Value $119M Shares 1,091,840 Share Price $109.14 Est. Cost/Share $64.47 Unrealized @ Report Date —
LLY LILLY ELI & CO 4.5%
Value $103M Shares 298,643 Share Price $343.42 * Est. Cost/Share $156.24 Unrealized @ Report Date +111.2%
PEN PENUMBRA INC 4.4%
Value $100M Shares 360,030 Share Price $278.69 * Est. Cost/Share $191.39 Unrealized @ Report Date +33.4%
CYTK CYTOKINETICS INC 3.7%
Value $84.44M Shares 2,399,545 Share Price $35.19 * Est. Cost/Share $24.28 Unrealized @ Report Date +68.0%
HUM HUMANA INC 3.6%
Value $80.62M Shares 166,066 Share Price $485.46 Est. Cost/Share $349.66 Unrealized @ Report Date +36.8%
CNC CENTENE CORP DEL 3.1%
Value $70.32M Shares 1,112,480 Share Price $63.21 * Est. Cost/Share $66.53 Unrealized @ Report Date +6.7%
IRTC IRHYTHM TECHNOLOGIES INC 2.7%
Value $60.21M Shares 485,468 Share Price $124.03 * Est. Cost/Share $91.74 Unrealized @ Report Date +18.2%
— OAK STR HEALTH INC 2.6%
Value $57.94M Shares 58,500,000 Share Price $0.99 Est. Cost/Share $0.78 Unrealized @ Report Date —
UNH UNITEDHEALTH GROUP INC 2.4%
Value $54.85M Shares 116,067 Share Price $472.59 * Est. Cost/Share $318.94 Unrealized @ Report Date +43.4%
EW EDWARDS LIFESCIENCES CORP 2.4%
Value $53.66M Shares 648,633 Share Price $82.73 * Est. Cost/Share $76.05 Unrealized @ Report Date +3.4%
DXCM DEXCOM INC 2.2%
Value $49.24M Shares 423,816 Share Price $116.18 * Est. Cost/Share $111.25 Unrealized @ Report Date +0.6%
MRK MERCK & CO INC 2.2%
Value $49.06M Shares 461,118 Share Price $106.39 * Est. Cost/Share $83.37 Unrealized @ Report Date +18.4%
CAH CARDINAL HEALTH INC 2.1%
Value $48.3M Shares 639,783 Share Price $75.50 * Est. Cost/Share $44.62 Unrealized @ Report Date +60.3%
ABBV ABBVIE INC 2.0%
Value $46.04M Shares 288,903 Share Price $159.37 * Est. Cost/Share $132.72 Unrealized @ Report Date +4.1%
ISRG INTUITIVE SURGICAL INC 2.0%
Value $45.69M Shares 178,863 Share Price $255.47 * Est. Cost/Share $244.74 Unrealized @ Report Date +0.7%
— SEAGEN INC 2.0%
Value $44.72M Shares 220,883 Share Price $202.47 Est. Cost/Share $172.31 Unrealized @ Report Date —
DHR DANAHER CORPORATION 2.0%
Value $44.28M Shares 175,690 Share Price $252.04 * Est. Cost/Share $143.93 Unrealized @ Report Date +55.7%
HUM HUMANA INC 1.9%
Value $42.67M Shares 87,900 Share Price $485.46 Est. Cost/Share $349.66 Unrealized @ Report Date +36.8%
QURE UNIQURE NV 1.9%
Value $42.5M Shares 2,110,070 Share Price $20.14 * Est. Cost/Share $16.59 Unrealized @ Report Date +26.5%
SNDX SYNDAX PHARMACEUTICALS INC 1.8%
Value $41.11M Shares 1,946,652 Share Price $21.12 * Est. Cost/Share $22.40 Unrealized @ Report Date +11.1%
IQV IQVIA HLDGS INC 1.8%
Value $39.98M Shares 201,037 Share Price $198.89 * Est. Cost/Share $144.71 Unrealized @ Report Date +47.7%
HCA HCA HEALTHCARE INC 1.7%
Value $39.16M Shares 148,500 Share Price $263.68 * Est. Cost/Share $214.29 Unrealized @ Report Date +15.7%
ARGX ARGENX SE 1.7%
Value $39.02M Shares 104,732 Share Price $372.58 Est. Cost/Share $378.88 Unrealized @ Report Date —
MOH MOLINA HEALTHCARE INC 1.7%
Value $38.46M Shares 143,779 Share Price $267.49 * Est. Cost/Share $221.27 Unrealized @ Report Date +29.9%
MCK MCKESSON CORP 1.7%
Value $37.67M Shares 105,811 Share Price $356.05 Est. Cost/Share $163.53 Unrealized @ Report Date +117.8%
PRTA PROTHENA CORP PLC 1.7%
Value $37.54M Shares 774,546 Share Price $48.47 * Est. Cost/Share $31.77 Unrealized @ Report Date +66.3%
AXSM AXSOME THERAPEUTICS INC 1.7%
Value $37.38M Shares 606,081 Share Price $61.68 * Est. Cost/Share $34.93 Unrealized @ Report Date +88.1%
BDX BECTON DICKINSON & CO 1.7%
Value $37.38M Shares 151,013 Share Price $247.54 * Est. Cost/Share $232.23 Unrealized @ Report Date 0.0%
— DYNAVAX TECHNOLOGIES CORP 1.6%
Value $37.33M Shares 3,805,370 Share Price $9.81 Est. Cost/Share $8.25 Unrealized @ Report Date —
TMO THERMO FISHER SCIENTIFIC INC 1.6%
Value $35.82M Shares 62,143 Share Price $576.37 * Est. Cost/Share $505.13 Unrealized @ Report Date +10.6%
— IVERIC BIO INC 1.6%
Value $35.66M Shares 1,465,483 Share Price $24.33 Est. Cost/Share $21.60 Unrealized @ Report Date —
UNH UNITEDHEALTH GROUP INC 1.4%
Value $30.58M Shares 64,700 Share Price $472.59 * Est. Cost/Share $318.94 Unrealized @ Report Date +43.4%
UHS UNIVERSAL HLTH SVCS INC 1.3%
Value $29.7M Shares 233,685 Share Price $127.10 * Est. Cost/Share $125.56 Unrealized @ Report Date +8.4%
WAT WATERS CORP 1.3%
Value $29.3M Shares 94,624 Share Price $309.63 * Est. Cost/Share $237.41 Unrealized @ Report Date +36.2%
AVTR AVANTOR INC 1.3%
Value $28.57M Shares 1,351,326 Share Price $21.14 * Est. Cost/Share $23.15 Unrealized @ Report Date -1.6%
RCUS ARCUS BIOSCIENCES INC 1.3%
Value $28.45M Shares 1,559,947 Share Price $18.24 * Est. Cost/Share $22.22 Unrealized @ Report Date -14.0%
CRBU CARIBOU BIOSCIENCES INC 1.2%
Value $26.61M Shares 5,012,118 Share Price $5.31 * Est. Cost/Share $17.80 Unrealized @ Report Date -65.0%
— KARUNA THERAPEUTICS INC 1.1%
Value $25.1M Shares 138,209 Share Price $181.64 Est. Cost/Share $124.27 Unrealized @ Report Date —
— POINT BIOPHARMA GLOBAL INC 1.0%
Value $23.3M Shares 3,204,790 Share Price $7.27 Est. Cost/Share $7.72 Unrealized @ Report Date —
LEGN LEGEND BIOTECH CORP 1.0%
Value $22.77M Shares 472,161 Share Price $48.22 Est. Cost/Share $48.22 Unrealized @ Report Date —
ACHC ACADIA HEALTHCARE COMPANY IN 1.0%
Value $22.47M Shares 310,935 Share Price $72.25 * Est. Cost/Share $77.95 Unrealized @ Report Date 0.0%
ASND ASCENDIS PHARMA A/S 1.0%
Value $21.67M Shares 202,115 Share Price $107.22 Est. Cost/Share $107.22 Unrealized @ Report Date —
THC TENET HEALTHCARE CORP 0.9%
Value $21.21M Shares 356,941 Share Price $59.42 * Est. Cost/Share $38.03 Unrealized @ Report Date +46.2%
ICUI ICU MED INC 0.9%
Value $20.24M Shares 122,703 Share Price $164.96 * Est. Cost/Share $172.03 Unrealized @ Report Date 0.0%
APLS APELLIS PHARMACEUTICALS INC 0.8%
Value $18.75M Shares 284,269 Share Price $65.96 * Est. Cost/Share $55.39 Unrealized @ Report Date +4.2%
BCRX BIOCRYST PHARMACEUTICALS INC 0.8%
Value $18.03M Shares 2,162,411 Share Price $8.34 * Est. Cost/Share $10.32 Unrealized @ Report Date -6.7%
— NEVRO CORP 0.7%
Value $16.45M Shares 17,500,000 Share Price $0.94 Est. Cost/Share $0.93 Unrealized @ Report Date —
ACLX ARCELLX INC 0.7%
Value $16.2M Shares 525,816 Share Price $30.81 Est. Cost/Share $22.94 Unrealized @ Report Date +32.3%
BMRN BIOMARIN PHARMACEUTICAL INC 0.7%
Value $15.52M Shares 159,566 Share Price $97.24 * Est. Cost/Share $84.08 Unrealized @ Report Date +23.3%
— BIOMARIN PHARMACEUTICAL INC 0.7%
Value $15.43M Shares 15,000,000 Share Price $1.03 Est. Cost/Share $1.04 Unrealized @ Report Date —
ELV ELEVANCE HEALTH INC 0.7%
Value $14.98M Shares 32,583 Share Price $459.81 Est. Cost/Share $450.89 Unrealized @ Report Date +1.0%
— BLUEBIRD BIO INC 0.6%
Value $14.58M Shares 4,585,782 Share Price $3.18 Est. Cost/Share $3.38 Unrealized @ Report Date —
ERAS ERASCA INC 0.6%
Value $14.44M Shares 4,797,460 Share Price $3.01 * Est. Cost/Share $16.12 Unrealized @ Report Date -77.4%
ICLR ICON PLC 0.6%
Value $13.76M Shares 64,417 Share Price $213.59 * Est. Cost/Share $192.01 Unrealized @ Report Date +15.9%
LLY LILLY ELI & CO 0.6%
Value $13.63M Shares 39,700 Share Price $343.42 * Est. Cost/Share $156.24 Unrealized @ Report Date +111.2%
— ESSA PHARMA INC 0.5%
Value $12.36M Shares 4,161,461 Share Price $2.97 Est. Cost/Share $2.61 Unrealized @ Report Date —
— MIRATI THERAPEUTICS INC 0.5%
Value $11.86M Shares 318,948 Share Price $37.18 Est. Cost/Share $37.18 Unrealized @ Report Date —
— GENERATION BIO CO 0.5%
Value $11.39M Shares 2,648,297 Share Price $4.30 Est. Cost/Share $6.61 Unrealized @ Report Date —
PRCT PROCEPT BIOROBOTICS CORP 0.4%
Value $9.082M Shares 319,782 Share Price $28.40 * Est. Cost/Share $37.46 Unrealized @ Report Date -5.8%
EDIT EDITAS MEDICINE INC 0.3%
Value $7.546M Shares 1,040,794 Share Price $7.25 * Est. Cost/Share $14.06 Unrealized @ Report Date -36.7%
IMVT IMMUNOVANT INC 0.3%
Value $7.172M Shares 462,431 Share Price $15.51 * Est. Cost/Share $17.35 Unrealized @ Report Date 0.0%
THC TENET HEALTHCARE CORP 0.3%
Value $6.572M Shares 110,600 Share Price $59.42 * Est. Cost/Share $38.03 Unrealized @ Report Date +46.2%
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.3%
Value $6.532M Shares 5,992,571 Share Price $1.09 Est. Cost/Share $2.36 Unrealized @ Report Date —
— OUTSET MED INC 0.3%
Value $5.98M Shares 324,982 Share Price $18.40 Est. Cost/Share $18.40 Unrealized @ Report Date —
HOWL WEREWOLF THERAPEUTICS INC 0.3%
Value $5.765M Shares 2,217,220 Share Price $2.60 * Est. Cost/Share $4.95 Unrealized @ Report Date -39.8%
XENE XENON PHARMACEUTICALS INC 0.2%
Value $3.584M Shares 100,147 Share Price $35.79 * Est. Cost/Share $36.85 Unrealized @ Report Date +0.2%
CELC CELCUITY INC 0.1%
Value $3.187M Shares 310,965 Share Price $10.25 * Est. Cost/Share $10.08 Unrealized @ Report Date +8.7%
— BELLUS HEALTH INC NEW 0.1%
Value $3.167M Shares 439,813 Share Price $7.20 Est. Cost/Share $7.35 Unrealized @ Report Date —
— VERVE THERAPEUTICS INC 0.1%
Value $2.683M Shares 186,087 Share Price $14.42 Est. Cost/Share $22.95 Unrealized @ Report Date —
CMPS COMPASS PATHWAYS PLC 0.1%
Value $2.443M Shares 246,064 Share Price $9.93 Est. Cost/Share $10.21 Unrealized @ Report Date —
— INHIBRX INC 0.1%
Value $2.292M Shares 121,447 Share Price $18.87 Est. Cost/Share $18.87 Unrealized @ Report Date —
PMVP PMV PHARMACEUTICALS INC 0.1%
Value $1.994M Shares 418,027 Share Price $4.77 * Est. Cost/Share $16.93 Unrealized @ Report Date -58.4%
— PRAXIS PRECISION MEDICINES I 0.1%
Value $1.761M Shares 2,176,594 Share Price $0.81 Est. Cost/Share $5.94 Unrealized @ Report Date —
— VECTIVBIO HLDG AG 0.0%
Value $1.123M Shares 131,922 Share Price $8.51 Est. Cost/Share $8.54 Unrealized @ Report Date —
IOBT IO BIOTECH INC 0.0%
Value $952K Shares 507,640 Share Price $1.88 * Est. Cost/Share $8.35 Unrealized @ Report Date -70.2%
KROS KEROS THERAPEUTICS INC 0.0%
Value $869K Shares 20,350 Share Price $42.70 * Est. Cost/Share $47.52 Unrealized @ Report Date +6.3%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.0%
Value $868K Shares 142,055 Share Price $6.11 * Est. Cost/Share $6.98 Unrealized @ Report Date -1.2%
SANA SANA BIOTECHNOLOGY INC 0.0%
Value $45,669 Shares 13,966 Share Price $3.27 * Est. Cost/Share $7.01 Unrealized @ Report Date -43.0%