Location: Boston, MA
CIK: 0001346824 · Show all filings
Period: Q2 2023 (← Previous) (Next →)
Filing Date: Aug 14, 2023
Total Value: $5.296B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | 11,225,357 | $1.002B | 18.9% | $79.32 | — | COM | 04351P101 |
| LEGN | LEGEND BIOTECH CORP | 6,264,707 | $432M | 8.2% | $58.19 | — | COM | 52490G102 |
| PCVX | VAXCYTE INC | 7,891,254 | $394M | 7.4% | $35.36 | +34.1% | SPONSORED ADS | 92243G108 |
| — | DICE THERAPEUTICS INC | 7,856,612 | $365M | 6.9% | $31.90 | — | COM | 23345J104 |
| — | 89BIO INC | 11,416,948 | $216M | 4.1% | $16.58 | — | COM | 282559103 |
| BIIB | BIOGEN INC | 532,892 | $152M | 2.9% | $216.32 | +37.7% | SPONSORED ADR | 09062X103 |
| — | AEROVATE THERAPEUTICS INC | 8,263,982 | $142M | 2.7% | $22.83 | — | COM | 008064107 |
| — | VERONA PHARMA PLC | 6,317,990 | $134M | 2.5% | $7.68 | — | COM | 925050106 |
| — | CUREVAC N V | 12,245,955 | $128M | 2.4% | $6.97 | — | COM | N2451R105 |
| TYRA | TYRA BIOSCIENCES INC | 7,236,454 | $123M | 2.3% | $19.11 | -24.1% | COM | 90240B106 |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 9,000,000 | $107M | 2.0% | $11.79 | +12.5% | ORD SHS | N62509109 |
| CTKB | CYTEK BIOSCIENCES INC | 12,297,721 | $105M | 2.0% | $20.70 | -56.7% | COM | 23285D109 |
| JANX | JANUX THERAPEUTICS INC | 8,670,644 | $103M | 1.9% | $22.27 | -40.0% | COM | 47103J105 |
| GERN | GERON CORP | 31,544,806 | $101M | 1.9% | $2.29 | +24.3% | COM | 374163103 |
| — | INHIBRX INC | 3,853,867 | $100M | 1.9% | $24.64 | — | SHS | 45720L107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 5,676,067 | $93.6M | 1.8% | $23.94 | -24.6% | COM | 76243J105 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 7,809,852 | $93.25M | 1.8% | $17.63 | -25.9% | COM | 23954D109 |
| RXST | RXSIGHT INC | 3,052,796 | $87.92M | 1.7% | $13.76 | +61.6% | COM | 78349D107 |
| COGT | COGENT COMMUNICATIONS HLDGS | 6,416,147 | $75.97M | 1.4% | $13.15 | -12.8% | COM | 19240Q201 |
| PEPG | PEPGEN INC | 8,131,952 | $72.7M | 1.4% | $11.15 | +17.2% | COM | 713317105 |
| AXSM | AXSOME THERAPEUTICS INC | 1,000,000 | $71.86M | 1.4% | $73.77 | 0.0% | CLASS A ORD SHS | 05464T104 |
| RNAM | AVIDITY BIOSCIENCES INC | 6,416,998 | $71.16M | 1.3% | $16.99 | -26.2% | COM | 05370A108 |
| — | VOR BIOPHARMA INC | 22,748,880 | $70.29M | 1.3% | $24.47 | — | COM | 929033108 |
| GHRS | GH RESEARCH PLC | 5,587,333 | $66.29M | 1.3% | $17.97 | -42.9% | SPONSORED ADR | G3855L106 |
| WVE | WAVE LIFE SCIENCES LTD | 17,202,009 | $62.62M | 1.2% | $8.85 | -54.4% | COM | Y95308105 |
| ACRV | ACRIVON THERAPEUTICS INC | 4,810,508 | $62.34M | 1.2% | $12.69 | -4.7% | COM | 004890109 |
| — | ICOSAVAX INC | 5,963,565 | $59.22M | 1.1% | $28.89 | — | COM | 45114M109 |
| — | ITEOS THERAPEUTICS INC | 4,417,259 | $58.48M | 1.1% | $24.67 | — | COM | 46565G104 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 3,069,531 | $55.47M | 1.0% | $18.41 | 0.0% | COM | 35104E100 |
| MLYS | MINERALYS THERAPEUTICS INC | 3,178,476 | $54.19M | 1.0% | $16.83 | -11.2% | COM | 603170101 |
| — | ALPINE IMMUNE SCIENCES INC | 4,691,178 | $48.23M | 0.9% | $7.23 | — | COM | 02083G100 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 2,007,946 | $47.77M | 0.9% | $25.89 | -0.9% | COM | 92790C104 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 9,770,773 | $47M | 0.9% | $16.64 | -71.2% | COMMON STOCK | 00509G209 |
| ACRS | ACLARIS THERAPEUTICS INC | 4,398,453 | $45.61M | 0.9% | $13.86 | -34.7% | SPONSORED ADS | 00461U105 |
| — | IMMUNOGEN INC | 2,329,958 | $43.97M | 0.8% | $5.49 | — | COM | 45253H101 |
| ELVN | ENLIVEN THERAPEUTICS INC | 2,122,465 | $43.32M | 0.8% | $20.34 | -0.6% | COM | 29337E102 |
| FULC | FULCRUM THERAPEUTICS INC | 11,609,704 | $38.31M | 0.7% | $7.35 | -60.0% | CLASS A COM | 359616109 |
| CLYM | ELIEM THERAPEUTICS INC | 13,150,849 | $36.82M | 0.7% | $20.66 | -85.3% | ADS | 28658R106 |
| TNYA | TENAYA THERAPEUTICS INC | 6,067,483 | $35.62M | 0.7% | $7.47 | -22.2% | COM | 87990A106 |
| ANTX | AN2 THERAPEUTICS INC | 3,773,517 | $32.07M | 0.6% | $15.13 | -52.5% | COM | 037326105 |
| PLRX | PLIANT THERAPEUTICS INC | 1,762,000 | $31.93M | 0.6% | $28.47 | -16.9% | COM | 729139105 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 3,370,506 | $29.32M | 0.6% | $11.52 | -47.0% | COM | 30233G209 |
| SPRY | ARS PHARMACEUTICALS INC | 3,009,678 | $20.16M | 0.4% | $6.49 | +2.3% | COM | 82835W108 |
| HOWL | WEREWOLF THERAPEUTICS INC | 6,144,881 | $18.74M | 0.4% | $10.47 | -73.1% | COM | 95075A107 |
| DSGN | DESIGN THERAPEUTICS INC | 2,971,231 | $18.72M | 0.4% | $27.75 | -77.9% | COM | 25056L103 |
| SLDB | SOLID BIOSCIENCES INC | 3,426,286 | $17.95M | 0.3% | $6.55 | -14.1% | COM | 83422E204 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 3,525,754 | $17.81M | 0.3% | $22.74 | -91.0% | COM | 09203E105 |
| NKTX | NKARTA INC | 7,805,129 | $17.09M | 0.3% | $24.86 | -82.3% | COM | 65487U108 |
| CELC | CELCUITY INC | 1,400,001 | $15.37M | 0.3% | $10.24 | +1.5% | COM | 15102K100 |
| — | IGM BIOSCIENCES INC | 937,500 | $8.653M | 0.2% | $9.23 | — | COM | 449585108 |
| — | CONNECT BIOPHARMA HLDGS LTD | 6,991,003 | $7.9M | 0.1% | $19.09 | — | COM | 207523101 |
| — | TALARIS THERAPEUTICS INC | 2,333,175 | $7.093M | 0.1% | $3.04 | — | COM | 87410C104 |
| — | NANOSTRING TECHNOLOGIES | 1,723,373 | $6.98M | 0.1% | $10.06 | — | ORDINARY SHARES | 63009R109 |
| NAMSW | NEWAMSTERDAM PHARMA COMPANY | 333,333 | $697K | 0.0% | $0.87 | — | ORD SHS | N62509117 |